Suzanne Devkota
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View article: Diet’s impact on gut microbial assemblage in health and disease
Diet’s impact on gut microbial assemblage in health and disease Open
The gut microbiome has been linked to everything from human behavior to athletic performance to disease pathogenesis. And yet, few universal truths have emerged regarding how the microbiome exerts its effects or responds to the host enviro…
View article: Antibiotic use during influenza infection augments lung eosinophils that impair immunity against secondary bacterial pneumonia
Antibiotic use during influenza infection augments lung eosinophils that impair immunity against secondary bacterial pneumonia Open
A leading cause of mortality after influenza infection is the development of a secondary bacterial pneumonia. In the absence of a bacterial superinfection, prescribing antibacterial therapies is not indicated but has become a common clinic…
View article: The gut microbiota and diabetes: research, translation, and clinical applications – 2023 Diabetes, Diabetes Care, and Diabetologia Expert Forum
The gut microbiota and diabetes: research, translation, and clinical applications – 2023 Diabetes, Diabetes Care, and Diabetologia Expert Forum Open
This article summarises the state of the science on the role of the gut microbiota (GM) in diabetes from a recent international expert forum organised by Diabetes , Diabetes Care , and Diabetologia , which was held at the European Associat…
View article: The Gut Microbiota and Diabetes: Research, Translation, and Clinical Applications—2023 <i>Diabetes</i>, <i>Diabetes Care</i>, and <i>Diabetologia</i> Expert Forum
The Gut Microbiota and Diabetes: Research, Translation, and Clinical Applications—2023 <i>Diabetes</i>, <i>Diabetes Care</i>, and <i>Diabetologia</i> Expert Forum Open
This article summarizes the state of the science on the role of the gut microbiota (GM) in diabetes from a recent international expert forum organized by Diabetes, Diabetes Care, and Diabetologia, which was held at the European Association…
View article: The Gut Microbiota and Diabetes: Research, Translation, and Clinical Applications—2023 <i>Diabetes</i>, <i>Diabetes Care</i>, and <i>Diabetologia</i> Expert Forum
The Gut Microbiota and Diabetes: Research, Translation, and Clinical Applications—2023 <i>Diabetes</i>, <i>Diabetes Care</i>, and <i>Diabetologia</i> Expert Forum Open
This article summarizes the state of the science on the role of the gut microbiota (GM) in diabetes from a recent international expert forum organized by Diabetes, Diabetes Care, and Diabetologia, which was held at the European Association…
View article: The intestinal microbiota contributes to the development of immune-mediated cardiovascular inflammation and vasculitis in mice
The intestinal microbiota contributes to the development of immune-mediated cardiovascular inflammation and vasculitis in mice Open
SUMMARY Alterations in the intestinal microbiota contribute to the pathogenesis of various cardiovascular disorders, but how they affect the development of Kawasaki disease (KD), an acute pediatric vasculitis, remains unclear. We report th…
View article: Pre-operative visceral adipose tissue radiodensity is a potentially novel prognostic biomarker for early endoscopic post-operative recurrence in Crohn’s disease
Pre-operative visceral adipose tissue radiodensity is a potentially novel prognostic biomarker for early endoscopic post-operative recurrence in Crohn’s disease Open
BACKGROUND Evidence suggests inflammatory mesenteric fat is involved in post-operative recurrence (POR) of Crohn’s disease (CD). However, its prognostic value is uncertain, in part, due to difficulties studying it non-invasively. AIM To ev…
View article: Microbial aromatic amino acid metabolism is modifiable in fermented food matrices to promote bioactivity
Microbial aromatic amino acid metabolism is modifiable in fermented food matrices to promote bioactivity Open
Ingestion of fermented foods impacts human immune function, yet the bioactive food components underlying these effects are not understood. Here, we interrogated whether fermented food bioactivity could be traced to a class of microbial met…
View article: Tissue microarray data and processing scripts for The molecular consequences of androgen activity in the human breast
Tissue microarray data and processing scripts for The molecular consequences of androgen activity in the human breast Open
This repository contains raw and processed data from the CODEX imaging dataset in this publication. The RAW data tables provide the resulting nuclei and membrane staining signals obtained from the nuclei segmentation described in the Metho…
View article: Tissue microarray data and processing scripts for The molecular consequences of androgen activity in the human breast
Tissue microarray data and processing scripts for The molecular consequences of androgen activity in the human breast Open
This repository contains raw and processed data from the CODEX imaging dataset in this publication. The RAW data tables provide the resulting nuclei and membrane staining signals obtained from the nuclei segmentation described in the Metho…
View article: The molecular consequences of androgen activity in the human breast
The molecular consequences of androgen activity in the human breast Open
Estrogen and progesterone have been extensively studied in the mammary gland, but the molecular effects of androgen remain largely unexplored. Transgender men are recorded as female at birth but identify as male and may undergo gender-affi…
View article: The systemic anti-microbiota IgG repertoire can identify gut bacteria that translocate across gut barrier surfaces
The systemic anti-microbiota IgG repertoire can identify gut bacteria that translocate across gut barrier surfaces Open
Unique gut microbiota compositions have been associated with inflammatory diseases, but identifying gut bacterial functions linked to immune activation in humans remains challenging. Translocation of pathogens from mucosal surfaces into pe…
View article: Gut microbiome and pancreatic cancer cachexia: An evolving relationship
Gut microbiome and pancreatic cancer cachexia: An evolving relationship Open
Nearly 80% of patients with pancreatic ductal adenocarcinoma (PDAC) develop cachexia along their disease course. Cachexia is characterized by progressive weight loss, muscle wasting, and systemic inflammation and has been linked to poorer …
View article: The molecular consequences of androgen activity in the human breast
The molecular consequences of androgen activity in the human breast Open
Summary The mammary gland has been extensively studied for estrogen and progesterone reactivity, but the molecular effects of androgen in the breast remain largely unexplored. Transgender men are recorded female at birth but identify as ma…
View article: Conceptual Exchanges for Understanding Free-Living and Host-Associated Microbiomes
Conceptual Exchanges for Understanding Free-Living and Host-Associated Microbiomes Open
Whether a microbe is free-living or associated with a host from across the tree of life, its existence depends on a limited number of elements and electron donors and acceptors. Yet divergent approaches have been used by investigators from…
View article: Psychobiology of Stress and Adolescent Depression (PSY SAD) Study: Protocol overview for an fMRI-based multi-method investigation
Psychobiology of Stress and Adolescent Depression (PSY SAD) Study: Protocol overview for an fMRI-based multi-method investigation Open
Depression is a common, often recurrent disorder that causes substantial disease burden worldwide, and this is especially true for women following the pubertal transition. According to the Social Signal Transduction Theory of Depression, s…
View article: Systemic IgG repertoire as a biomarker for translocating gut microbiota members
Systemic IgG repertoire as a biomarker for translocating gut microbiota members Open
While the microbiota has been associated with diseases states, how specific alterations in composition, function, or localization contribute to pathologies remains unclear. The ability of defined microbes to translocate has been linked to …
View article: Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22
Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22 Open
Significance Alcoholic hepatitis (AH) is a severe form of alcohol-associated liver disease (ALD) that is characterized by chronic liver injury and inflammation. The current treatment strategy for AH involves the use of corticosteroids, des…
View article: Editorial: Gastronomic Science
Editorial: Gastronomic Science Open
EDITORIAL article Front. Physiol., 27 October 2020 | https://doi.org/10.3389/fphys.2020.612921
View article: The new microbiology: cultivating the future of microbiome-directed medicine
The new microbiology: cultivating the future of microbiome-directed medicine Open
The discovery of human-associated microscopic life forms has captivated the scientific community since their first documentation in the 17th century. Subsequent isolation and cultivation of microorganisms have spurred great leaps in medici…