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View article: Suppl. Figure 4 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis
Suppl. Figure 4 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis Open
Anti-ENG therapy is active against MPNST xenografts.
View article: Supplementary Data 3 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis
Supplementary Data 3 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis Open
Dual inhibition of ENG and MEK efficiently blocks ENG-Smad1/5 and MAPK/ERK pathway activation in ST88-14 cells.
View article: Suppl. Figure 2 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis
Suppl. Figure 2 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis Open
ENG knockdown leads to downregulation of pro-angiogenic and pro-metastatic gene signatures in MPNST cells.
View article: Suppl. Figure 3 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis
Suppl. Figure 3 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis Open
ENG knockdown does not affect MPNST cell apoptosis in vivo.
View article: Suppl. Figure 5 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis
Suppl. Figure 5 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis Open
Combined anti-ENG/anti-MEK therapy inhibits MPNST growth without toxicity in vivo.
View article: Bioactive Enhanced Adjuvant Chemokine Oligonucleotide Nanoparticles (BEACONs) for Mucosal Vaccination Against Genital Herpes
Bioactive Enhanced Adjuvant Chemokine Oligonucleotide Nanoparticles (BEACONs) for Mucosal Vaccination Against Genital Herpes Open
Genital herpes, caused primarily by herpes simplex virus-2 (HSV-2), remains a highly prevalent sexually transmitted infection with no available vaccine. Previous intramuscular vaccination strategies have failed to protect against HSV-2 inf…
View article: Supplementary Data 2 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Supplementary Data 2 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
Significant deregulated genes in shENG versus shScramble STS26T cells.
View article: Suppl. Figure 4 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Suppl. Figure 4 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
Anti-ENG therapy is active against MPNST xenografts.
View article: Suppl. Figure 4 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Suppl. Figure 4 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
Anti-ENG therapy is active against MPNST xenografts.
View article: Data from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Data from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
Purpose: Malignant peripheral nerve sheath tumors (MPNSTs) are highly aggressive soft-tissue sarcomas that lack effective treatments, underscoring the urgent need to uncover novel mediators of MPNST pathogenesis that may serve as potential…
View article: Supplementary Data 1 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Supplementary Data 1 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
Taqman probes used for quantitative PCR.
View article: Suppl. Figure 1 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Suppl. Figure 1 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
Analysis of ENG expression and plasma circulating sEVs in human PNSTs.
View article: Suppl. Figure 3 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Suppl. Figure 3 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
ENG knockdown does not affect MPNST cell apoptosis in vivo.
View article: Supplementary Data 2 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Supplementary Data 2 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
Significant deregulated genes in shENG versus shScramble STS26T cells.
View article: Suppl. Figure 6 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Suppl. Figure 6 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
Dual inhibition of ENG and MEK efficiently blocks ENG-Smad1/5 and MAPK/ERK pathway activation in ST88-14 cells.
View article: Supplementary Data 3 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Supplementary Data 3 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
Dual inhibition of ENG and MEK efficiently blocks ENG-Smad1/5 and MAPK/ERK pathway activation in ST88-14 cells.
View article: Supplementary Data 3 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Supplementary Data 3 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
Dual inhibition of ENG and MEK efficiently blocks ENG-Smad1/5 and MAPK/ERK pathway activation in ST88-14 cells.
View article: Suppl. Figure 5 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Suppl. Figure 5 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
Combined anti-ENG/anti-MEK therapy inhibits MPNST growth without toxicity in vivo.
View article: Suppl. Figure 2 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Suppl. Figure 2 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
ENG knockdown leads to downregulation of pro-angiogenic and pro-metastatic gene signatures in MPNST cells.
View article: Suppl. Figure 5 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Suppl. Figure 5 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
Combined anti-ENG/anti-MEK therapy inhibits MPNST growth without toxicity in vivo.
View article: Suppl. Figure 1 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Suppl. Figure 1 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
Analysis of ENG expression and plasma circulating sEVs in human PNSTs.
View article: Supplementary Data 1 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Supplementary Data 1 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
Taqman probes used for quantitative PCR.
View article: Suppl. Figure 6 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Suppl. Figure 6 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
Dual inhibition of ENG and MEK efficiently blocks ENG-Smad1/5 and MAPK/ERK pathway activation in ST88-14 cells.
View article: Suppl. Figure 2 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Suppl. Figure 2 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
ENG knockdown leads to downregulation of pro-angiogenic and pro-metastatic gene signatures in MPNST cells.
View article: Suppl. Figure 3 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
Suppl. Figure 3 from Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis Open
ENG knockdown does not affect MPNST cell apoptosis in vivo.
View article: Identification and validation of extracellular vesicle reference genes for the normalization of RT‐qPCR data
Identification and validation of extracellular vesicle reference genes for the normalization of RT‐qPCR data Open
Extracellular vesicles (EVs) contain a plethora of biomolecules, including nucleic acids, with diverse diagnostic and therapeutic application potential. Although reverse transcription‐quantitative PCR (RT‐qPCR) is the most widely applied l…
View article: Generation of post-surgical minimal residual disease models to investigate metastasis in soft tissue sarcoma patient-derived orthotopic xenografts
Generation of post-surgical minimal residual disease models to investigate metastasis in soft tissue sarcoma patient-derived orthotopic xenografts Open
View article: Compartmentalized ocular lymphatic system mediates eye–brain immunity
Compartmentalized ocular lymphatic system mediates eye–brain immunity Open
The eye, an anatomical extension of the central nervous system (CNS), exhibits many molecular and cellular parallels to the brain. Emerging research demonstrates that changes in the brain are often reflected in the eye, particularly in the…
View article: Jennifer Lisa Koslow, <i>Exhibiting Health: Public Health Displays in the Progressive Era</i> New Brunswick, NJ: Rutgers University Press, 2020. Pp. 160. ISBN 978-1-9788-0326-8. $33.95 (paperback).
Jennifer Lisa Koslow, <i>Exhibiting Health: Public Health Displays in the Progressive Era</i> New Brunswick, NJ: Rutgers University Press, 2020. Pp. 160. ISBN 978-1-9788-0326-8. $33.95 (paperback). Open
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View article: Suppl. Figure 5 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis
Suppl. Figure 5 from Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis Open
Combined anti-ENG/anti-MEK therapy inhibits MPNST growth without toxicity in vivo.