Suzanne Nielsen
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View article: Behavioural Effects and Naloxone Effectiveness With New Synthetic Opioids
Behavioural Effects and Naloxone Effectiveness With New Synthetic Opioids Open
Introduction The global drug market has seen an emergence of potent synthetic opioids, including benzimidazole‐derived substances known as nitazenes. These compounds have been implicated in fatal and non‐fatal overdoses. This review aims t…
View article: Complex trauma and perceived barriers to treatment among people accessing a supervised injecting facility
Complex trauma and perceived barriers to treatment among people accessing a supervised injecting facility Open
Introduction: People who inject drugs (PWID) have an elevated risk of trauma exposure, which can adversely affect health outcomes and create barriers to engaging with services. While high rates of post-traumatic stress disorder (PTS…
View article: A multisite pilot type 2 hybrid implementation-effectiveness trial of a community pharmacist-led model of collaborative care for Medication Assisted Treatment for Opioid Dependence: outcomes of the EPIC-MATOD trial
A multisite pilot type 2 hybrid implementation-effectiveness trial of a community pharmacist-led model of collaborative care for Medication Assisted Treatment for Opioid Dependence: outcomes of the EPIC-MATOD trial Open
ACTRN12621000871842.
View article: Creating Safer Injecting Practices Through Community‐Led Harm Reduction: Lessons From People Who Use Steroids for the Alcohol and Other Drug Sector
Creating Safer Injecting Practices Through Community‐Led Harm Reduction: Lessons From People Who Use Steroids for the Alcohol and Other Drug Sector Open
Introduction Research on anabolic–androgenic steroid (AAS) use has addressed health outcomes, social dynamics, service access and risk management strategies. Yet little work has examined how these domains converge in injection practices, w…
View article: Pregabalin dependence, withdrawal, suicidality and psychosis reports: A disproportionality analysis of the Australian adverse events database
Pregabalin dependence, withdrawal, suicidality and psychosis reports: A disproportionality analysis of the Australian adverse events database Open
Aims Globally, Australia has the highest per capita consumption rate of pregabalin, commonly prescribed for neuropathic pain. Emerging evidence suggests pregabalin may be associated with the onset or recurrence of several potentially life‐…
View article: Feasibility of direct induction onto long-acting injectable buprenorphine
Feasibility of direct induction onto long-acting injectable buprenorphine Open
This case series provides evidence that direct induction onto LAIB is feasible with rates of precipitated withdrawal similar to those previously reported for sublingual buprenorphine induction. Given the benefits of direct induction, in su…
View article: Healthcare Practitioner and Other Professionals' Perspectives on Gabapentinoid Misuse and Dependence: A Systematic Review of Qualitative Studies
Healthcare Practitioner and Other Professionals' Perspectives on Gabapentinoid Misuse and Dependence: A Systematic Review of Qualitative Studies Open
Background and Objective The global rise in gabapentinoid prescriptions for chronic pain has been striking. However, this trend has been accompanied by growing concerns about misuse and dependence. This qualitative systematic review aimed …
View article: Lead Astray? The Hidden Contaminants in Australian Anabolic–Androgenic Steroid Market and Their Potential Health Impact
Lead Astray? The Hidden Contaminants in Australian Anabolic–Androgenic Steroid Market and Their Potential Health Impact Open
Introduction Unregulated anabolic–androgenic steroid (AAS) markets are a global phenomenon with significant variability in product composition and purity. This study aimed to determine the chemical composition of AAS sold in Australia. Met…
View article: An evidence-based digital prescription opioid safety toolkit for national dissemination: co-design and user testing
An evidence-based digital prescription opioid safety toolkit for national dissemination: co-design and user testing Open
Introduction Australia has one of the highest rates of opioid prescribing and prescription opioid-related harm in the world. Although effective for pain relief, the use of prescription opioids is a leading cause of preventable morbidity an…
View article: The Digital Library of Health Care Consultations and Simulated Health Care Student Teaching: Protocol for a Repository of Recordings to Support Communication Research
The Digital Library of Health Care Consultations and Simulated Health Care Student Teaching: Protocol for a Repository of Recordings to Support Communication Research Open
Background Miscommunication in health care is a major source of poor health outcomes, complaints about health care professionals, and poor patient satisfaction. Recordings from real-life consultations provide valuable data for communicatio…
View article: Prescription opioid supply‐restricting policies and hospital use by people prescribed opioid medications, Victoria, 2018–22: a controlled interrupted time series analysis
Prescription opioid supply‐restricting policies and hospital use by people prescribed opioid medications, Victoria, 2018–22: a controlled interrupted time series analysis Open
Objectives To investigate the combined effect of two policies for reducing prescription opioid supply in Australia on hospital use by people prescribed opioids in primary care. Study design Retrospective data linkage study; controlled inte…
View article: A Scoping Review of the Emergence of Novel Synthetic Opioids in Australian Drug Markets: What Does This Mean for Harm Reduction Responses?
A Scoping Review of the Emergence of Novel Synthetic Opioids in Australian Drug Markets: What Does This Mean for Harm Reduction Responses? Open
Issues Rising synthetic opioid deaths in North America, and the emergence of nitazene harms has driven concern about novel synthetic opioids (NSO) in Australia. This scoping review aimed to map what is known about NSOs in Australia. Approa…
View article: Identifying key risk factors for intentional self‐harm, including suicide, among a cohort of people prescribed opioid agonist treatment: A predictive modelling study
Identifying key risk factors for intentional self‐harm, including suicide, among a cohort of people prescribed opioid agonist treatment: A predictive modelling study Open
Background and aims People with opioid use disorder are at increased risk of intentional self‐harm and suicide. Although risk factors are well known, most tools for identifying individuals at highest risk of these behaviours have limited c…
View article: Prevalence and risk factors for opioid overdose among women: A systematic review and meta-analysis
Prevalence and risk factors for opioid overdose among women: A systematic review and meta-analysis Open
The prevalence of opioid overdoses varies greatly among women by subpopulation and opioid type. Overdose is generally less common among women compared to men, yet where intentional self-harm or repeated overdose occurs, and among community…
View article: Use of Medicare-subsidised treatment services among people prescribed opioids for chronic non-cancer pain
Use of Medicare-subsidised treatment services among people prescribed opioids for chronic non-cancer pain Open
Objectives Australians receive healthcare services subsidised by the Medicare national health insurance scheme, including through the Chronic Disease Management Initiative supporting primary care management of chronic conditions. The use o…
View article: Understanding the first prescription: clinical and demographic drivers of strong opioid use in primary care
Understanding the first prescription: clinical and demographic drivers of strong opioid use in primary care Open
Aim To evaluate the demographic and clinical factors that influence the initiation of weak versus strong opioids among opioid-naïve patients in Australian primary care settings. Methods This retrospective cohort study focused on opioid-naï…
View article: Early High-Risk Opioid Prescribing and Persistent Opioid Use in Australian Workers with Workers’ Compensation Claims for Back and Neck Musculoskeletal Disorders or Injuries: A Retrospective Cohort Study
Early High-Risk Opioid Prescribing and Persistent Opioid Use in Australian Workers with Workers’ Compensation Claims for Back and Neck Musculoskeletal Disorders or Injuries: A Retrospective Cohort Study Open
View article: Protocol for the ‘Beyond 50’ prospective observational cohort study: Investigating the impact of physical and psychosocial factors on healthy ageing
Protocol for the ‘Beyond 50’ prospective observational cohort study: Investigating the impact of physical and psychosocial factors on healthy ageing Open
Background Older adults exhibit unique risks for depression and anxiety, and the current generation of 50–70-year-olds are more likely to engage in risky drinking patterns or use illicit substances than previous generations. Changing metab…
View article: National consensus statement on opioid agonist treatment in custodial settings
National consensus statement on opioid agonist treatment in custodial settings Open
Introduction Opioid use and dependence are prevalent among incarcerated people, contributing to elevated rates of overdose and other harms in this population. Opioid agonist treatment (OAT) has been shown to be an effective intervention to…
View article: Longitudinal patterns of opioid dispensing dosages for compensated Australian workers with low back pain: a 3.5-year follow-up study
Longitudinal patterns of opioid dispensing dosages for compensated Australian workers with low back pain: a 3.5-year follow-up study Open
Objective To identify longitudinal patterns in opioid dispensing dosages for workers with low back pain within a workers’ compensation setting and to explore the risk factors associated with high-dose and persistent opioid use. Method We i…
View article: Clinical and mental health characteristics among patients receiving medications for opioid use disorder treatment versus patients receiving low- and high-dose opioids when referred for pain management
Clinical and mental health characteristics among patients receiving medications for opioid use disorder treatment versus patients receiving low- and high-dose opioids when referred for pain management Open
Objective To examine the demographic and clinical characteristics of patients attending pain management services who were receiving opioid agonist treatment (ie, methadone or buprenorphine for the treatment of opioid use disorder) in compa…
View article: What influences Australian pharmacists' decisions to supply opioids? Results from a survey and randomised controlled factorial experiment
What influences Australian pharmacists' decisions to supply opioids? Results from a survey and randomised controlled factorial experiment Open
Introduction Prescription drug monitoring programs (PDMP) identify medication‐related risks to support clinical decision‐making. This study aims to report prescription medication refusal rates based on PDMP alerts and determine how PDMP al…
View article: How Can We Make Information on Equity in Clinical Guidelines More Usable for Clinicians? A Case Study Methodology of General Practitioners
How Can We Make Information on Equity in Clinical Guidelines More Usable for Clinicians? A Case Study Methodology of General Practitioners Open
Background Clinical practice guidelines (CPGs) are moving toward greater consideration of population‐level differences, like health inequities, when creating management recommendations. CPGs have the potential to reduce or perpetuate healt…
View article: Australian Community Pharmacists' Preparedness to Offer and Discuss Hepatitis C Testing and Treatment With Pharmacy Clients: A Representative Cross‐Sectional Survey
Australian Community Pharmacists' Preparedness to Offer and Discuss Hepatitis C Testing and Treatment With Pharmacy Clients: A Representative Cross‐Sectional Survey Open
The World Health Organisation (WHO) has set goals to eliminate hepatitis C (HCV) as a global health threat by 2030. To meet this goal, Australia must increase testing and diagnosis, including expanding access to care through community phar…
View article: An Evidence-Based Digital Prescription Opioid Safety Toolkit for National Dissemination: Co-design and User Testing (Preprint)
An Evidence-Based Digital Prescription Opioid Safety Toolkit for National Dissemination: Co-design and User Testing (Preprint) Open
BACKGROUND Australia has one of the highest rates of opioid prescribing and prescription opioid-related harm in the world. Although effective for acute pain relief, the use of prescription opioids is a leading cause of preventable morbidi…
View article: Revisiting the Oxycontin Reformulation: The Role of Licit Substitutes
Revisiting the Oxycontin Reformulation: The Role of Licit Substitutes Open
View article: Feasiblity of Direct Induction Onto Long-Acting Injectable Buprenorphine
Feasiblity of Direct Induction Onto Long-Acting Injectable Buprenorphine Open
View article: Australian community pharmacists’ experiences of prescription drug monitoring programs: Comparisons between mandated and nonmandated states
Australian community pharmacists’ experiences of prescription drug monitoring programs: Comparisons between mandated and nonmandated states Open
There were significant differences in pharmacists' PDMP experiences between mandated and nonmandated states, which may have policy implications given Australia's recent investment into national prescription monitoring.
View article: Initiation of buprenorphine in the emergency department or emergency out-of-hospital setting: A mixed-methods systematic review
Initiation of buprenorphine in the emergency department or emergency out-of-hospital setting: A mixed-methods systematic review Open
The initiation of buprenorphine in the ED setting is associated with higher odds of short and medium-term treatment engagement. Further research is required into EMS-initiated buprenorphine, as well as patient perspectives of ED- and EMS-i…
View article: Global perspectives on opioid use: shifting the conversation from deprescribing to quality use of medicines
Global perspectives on opioid use: shifting the conversation from deprescribing to quality use of medicines Open