Sven Benson
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View article: The association between test anxiety, learning strategies, and open-label placebo effects on academic test performance: a secondary analysis of a randomized controlled trial
The association between test anxiety, learning strategies, and open-label placebo effects on academic test performance: a secondary analysis of a randomized controlled trial Open
Introduction The management of educational stressors and predictors of cognitive performance outcomes, such as test anxiety and learning strategies (LS), pose relevant challenges for students and educators. In a previously published single…
View article: Placebo effects improve sickness symptoms and drug efficacy during systemic inflammation: a randomized controlled trial in human experimental endotoxemia
Placebo effects improve sickness symptoms and drug efficacy during systemic inflammation: a randomized controlled trial in human experimental endotoxemia Open
Background Systemic inflammation triggers a wide range of sickness symptoms, including bodily discomfort and affective symptoms, which are relevant to numerous health conditions. While extensive research in the placebo field demonstrates t…
View article: Living with Chronic Kidney Disease and Kidney Transplantation During COVID-19: A Study of Psychological and Behavioral Impacts
Living with Chronic Kidney Disease and Kidney Transplantation During COVID-19: A Study of Psychological and Behavioral Impacts Open
Background: Psychological impacts of the coronavirus disease 2019 (COVID-19) pandemic on individuals with chronic medical conditions remain understudied. Chronic kidney disease (CKD) is one of the chronic conditions associated with an incr…
View article: Supporting mental health of medical students: Needs and demands concerning an e-mental health application within medical education
Supporting mental health of medical students: Needs and demands concerning an e-mental health application within medical education Open
Background: Digital technologies are increasingly integrated into medical education and healthcare services. Studies have demonstrated the efficacy of e-mental health approaches, offering cost-effective, user-friendly, anonymous, and geogr…
View article: Baseline Pathological Liver Function Tests in Patients With Psoriasis Support the Indication for Systemic Therapy Rather Than Being a Reason Against It: A Real-World Analysis
Baseline Pathological Liver Function Tests in Patients With Psoriasis Support the Indication for Systemic Therapy Rather Than Being a Reason Against It: A Real-World Analysis Open
This study provides real world evidence that systemic therapy with secukinumab, ixekizumab, adalimumab, or apremilast does not present a general risk, but rather an opportunity for patients with psoriasis with elevated LFTs at baseline.
View article: Optimized communication during risk disclosure to reduce nocebo headache after lumbar puncture—a study protocol for a randomized controlled clinical trial
Optimized communication during risk disclosure to reduce nocebo headache after lumbar puncture—a study protocol for a randomized controlled clinical trial Open
Risk communication has been found to be a driver of nocebo effects in medical settings by enhancing negative expectations. In fact, merely disclosing the risk of side effects and complications of treatments or medical procedures increases …
View article: Evidence-informed language: interpretation and impact on intentions to treat – results of an online survey of medical students and specialists in German-speaking countries
Evidence-informed language: interpretation and impact on intentions to treat – results of an online survey of medical students and specialists in German-speaking countries Open
Objectives Currently, there is no generally accepted consensus on how to translate strength of evidence into language. Against this background, we here investigated how widely used verbal descriptors of evidence grades and clinical practic…
View article: Corrigendum: Preoperative Anxiolysis and Treatment Expectation (PATE Trial): open-label placebo treatment to reduce preoperative anxiety in female patients undergoing gynecological laparoscopic surgery – study protocol for a bicentric, prospective, randomized-controlled trial
Corrigendum: Preoperative Anxiolysis and Treatment Expectation (PATE Trial): open-label placebo treatment to reduce preoperative anxiety in female patients undergoing gynecological laparoscopic surgery – study protocol for a bicentric, prospective, randomized-controlled trial Open
[This corrects the article DOI: 10.3389/fpsyt.2024.1396562.].
View article: Medical Students’ Acceptance of Tailored e–Mental Health Apps to Foster Their Mental Health: Cross-Sectional Study
Medical Students’ Acceptance of Tailored e–Mental Health Apps to Foster Their Mental Health: Cross-Sectional Study Open
Background Despite the high prevalence of mental health problems among medical students and physicians, help-seeking remains low. Digital mental health approaches offer beneficial opportunities to increase well-being, for example, via mobi…
View article: “Powerful placebo”: A teaching and learning concept addressing placebo and nocebo effects in competency-based communication training
“Powerful placebo”: A teaching and learning concept addressing placebo and nocebo effects in competency-based communication training Open
Aim: Placebo and nocebo effects are based on expectations that are formed by how doctors communicate and can influence the efficacy of medical treatment. Given the implications for doctor-patient communication and the learning objectives l…
View article: Preoperative Anxiolysis and Treatment Expectation (PATE Trial): open-label placebo treatment to reduce preoperative anxiety in female patients undergoing gynecological laparoscopic surgery – study protocol for a bicentric, prospective, randomized-controlled trial
Preoperative Anxiolysis and Treatment Expectation (PATE Trial): open-label placebo treatment to reduce preoperative anxiety in female patients undergoing gynecological laparoscopic surgery – study protocol for a bicentric, prospective, randomized-controlled trial Open
One of the most common concerns of patients undergoing surgery is preoperative anxiety, with a prevalence of up to 48%. The effects of preoperative anxiety continue beyond the preoperative period and are associated with more severe postope…
View article: How effective is simple mechanical wound debridement in reducing bacterial colonisation? Results of a prospective clinical study
How effective is simple mechanical wound debridement in reducing bacterial colonisation? Results of a prospective clinical study Open
Background and aims: Bacteria in wounds can lead to stagnation of wound healing as well as to local or even systemic wound infections up to potentially lethal sepsis. Consequently, the bacterial load should be reduced as part of wound trea…
View article: Music Therapy as a Topic in Medical Education: Course Concept and Student Evaluation of an Elective Course for Medical Students
Music Therapy as a Topic in Medical Education: Course Concept and Student Evaluation of an Elective Course for Medical Students Open
OBJECTIVES Music therapy has been proven as a safe and well-established intervention in healthcare to relieve symptoms and improve quality of life. While music therapy is already established in several settings to supplement medical care, …
View article: Study protocol: effects of treatment expectation toward repetitive transcranial magnetic stimulation (rTMS) in major depressive disorder—a randomized controlled clinical trial
Study protocol: effects of treatment expectation toward repetitive transcranial magnetic stimulation (rTMS) in major depressive disorder—a randomized controlled clinical trial Open
Background Patients’ expectations toward any given treatment are highly important for the effectiveness of such treatment, as has been demonstrated for several disorders. In particular, in major depressive disorder (MDD), one of the most f…
View article: How familiar are German dermatologists with placebo and nocebo effects and to what extent are these targeted in clinical practice: A survey within the dermatological community
How familiar are German dermatologists with placebo and nocebo effects and to what extent are these targeted in clinical practice: A survey within the dermatological community Open
Background Every medical treatment inevitably comprises not only physiological, but also psychological components, reflected by placebo and nocebo effects, which significantly affect treatment outcome. However, the extent of knowledge on t…
View article: Amplified gut feelings under inflammation and depressed mood: A randomized fMRI trial on interoceptive pain in healthy volunteers
Amplified gut feelings under inflammation and depressed mood: A randomized fMRI trial on interoceptive pain in healthy volunteers Open
Results support an interplay of inflammation and sad mood on striatal and hippocampal circuitry engaged during visceral pain anticipation as well as on pain experience. This may reflect a nocebo mechanism, which may contribute to altered p…
View article: Continuous Glucose Monitoring of Steroid-Induced Hyperglycemia in Patients With Dermatologic Diseases
Continuous Glucose Monitoring of Steroid-Induced Hyperglycemia in Patients With Dermatologic Diseases Open
Background and Objectives: Systemic administration of glucocorticoids is a mainstay therapy for various inflammatory diseases and may lead to hyperglycemia, which carries the risk of worsening preexisting diabetes and triggering steroid-in…
View article: Supplementary Material for: Endotoxin-induced physiological and psychological sickness responses in healthy humans: insights into the post-acute phase
Supplementary Material for: Endotoxin-induced physiological and psychological sickness responses in healthy humans: insights into the post-acute phase Open
Introduction: Experimental endotoxemia is a translational model of systemic inflammation that has contributed significantly to our current understanding of sickness behavior and inflammation-associated depression. Previous studies using th…
View article: Endotoxin-Induced Physiological and Psychological Sickness Responses in Healthy Humans: Insights into the Post-Acute Phase
Endotoxin-Induced Physiological and Psychological Sickness Responses in Healthy Humans: Insights into the Post-Acute Phase Open
Introduction: Experimental endotoxemia is a translational model of systemic inflammation that has contributed significantly to our current understanding of sickness behavior and inflammation-associated depression. Previous studies using th…
View article: How Can Experimental Endotoxemia Contribute to Our Understanding of Pain? A Narrative Review
How Can Experimental Endotoxemia Contribute to Our Understanding of Pain? A Narrative Review Open
The immune system and the central nervous system exchange information continuously. This communication is a prerequisite for adaptive responses to physiological and psychological stressors. While the implicate relationship between inflamma…
View article: Supplementary Material for: Endotoxin-induced physiological and psychological sickness responses in healthy humans: insights into the post-acute phase
Supplementary Material for: Endotoxin-induced physiological and psychological sickness responses in healthy humans: insights into the post-acute phase Open
Introduction: Experimental endotoxemia is a translational model of systemic inflammation that has contributed significantly to our current understanding of sickness behavior and inflammation-associated depression. Previous studies using th…
View article: Implications of an HbA1c-based Diabetes Screening on Prevalence and Effect of Dysglycemia in Patients With COVID-19
Implications of an HbA1c-based Diabetes Screening on Prevalence and Effect of Dysglycemia in Patients With COVID-19 Open
Context In patients with severe acute respiratory syndrome coronavirus type 2 infection, diabetes is associated with poor COVID-19 prognosis. However, case detection strategy is divergent and reported prevalence varies from 5% to 35%. Obje…
View article: Experience with an OSCE anamnesis station via Zoom: Feasibility, acceptance and challenges from the perspective of students, simulated patients and examiners during the COVID-19 pandemic
Experience with an OSCE anamnesis station via Zoom: Feasibility, acceptance and challenges from the perspective of students, simulated patients and examiners during the COVID-19 pandemic Open
Aim: Assessments of practical clinical competencies pose a challenge during the COVID-19 pandemic. Reports about OSCE stations administered online show that, despite technical feasibility and acceptance, there is a lingering desire for in-…
View article: Circulating Pro-inflammatory Cytokines Do Not Explain Interindividual Variability in Visceral Sensitivity in Healthy Individuals
Circulating Pro-inflammatory Cytokines Do Not Explain Interindividual Variability in Visceral Sensitivity in Healthy Individuals Open
A role of the immune system in the pathophysiology of pain and hyperalgesia has received growing attention, especially in the context of visceral pain and the gut-brain axis. While acute experimental inflammation can induce visceral hypera…
View article: Can positive expectations help to improve the learning of risk literacy? A cluster-randomized study in undergraduate medical students
Can positive expectations help to improve the learning of risk literacy? A cluster-randomized study in undergraduate medical students Open
Background Risk literacy, i.e., the ability to calculate and apply risk parameters, represents a key competence for risk communication and medical decision making. However, risk literacy is reportedly low in medical students. The successfu…
View article: Positive Treatment Expectations Shape Perceived Medication Efficacy in a Translational Placebo Paradigm for the Gut-Brain Axis
Positive Treatment Expectations Shape Perceived Medication Efficacy in a Translational Placebo Paradigm for the Gut-Brain Axis Open
Placebo research has established the pivotal role of treatment expectations in shaping symptom experience and patient-reported treatment outcomes. Perceived treatment efficacy constitutes a relevant yet understudied aspect, especially in t…
View article: A brief screening tool for depression in psoriasis patients: The Two Questions Test in clinical practice
A brief screening tool for depression in psoriasis patients: The Two Questions Test in clinical practice Open
Patients suffering from chronic inflammatory diseases such as psoriasis are prone to develop depressive symptoms. However, within the time constraints of dermatological clinics, depressive symptoms in psoriasis patients are often overlooke…
View article: Assessment of Childbirth-Related PTSD: Psychometric Properties of the German Version of the City Birth Trauma Scale
Assessment of Childbirth-Related PTSD: Psychometric Properties of the German Version of the City Birth Trauma Scale Open
Background: About 3–4% of women in community samples suffer from childbirth-related posttraumatic stress disorder (PTSD). Surprisingly, the recently developed City Birth Trauma Scale (City BiTS) was the first diagnostic tool for childbirth…