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View article: Establishment and characterization of persistent <i>Pseudomonas aeruginosa</i> infections in air–liquid interface cultures of human airway epithelial cells
Establishment and characterization of persistent <i>Pseudomonas aeruginosa</i> infections in air–liquid interface cultures of human airway epithelial cells Open
Bacteria exhibit distinct behaviors in laboratory settings compared to infection environments. The presence of host cells induces changes in bacterial activity, while pathogens trigger immune responses that shape the microenvironment. Stud…
View article: Tetramerization is essential for the enzymatic function of the <i>Pseudomonas aeruginosa</i> virulence factor UDP-glucose pyrophosphorylase
Tetramerization is essential for the enzymatic function of the <i>Pseudomonas aeruginosa</i> virulence factor UDP-glucose pyrophosphorylase Open
Multidrug-resistant bacteria such as the opportunistic pathogen Pseudomonas aeruginosa , which causes life-threatening infections especially in immunocompromised individuals and cystic fibrosis patients, pose an increasing threat to public…
View article: Epithelial Dual Oxidase 2 Shapes the Mucosal Microbiome and Contributes to Inflammatory Susceptibility
Epithelial Dual Oxidase 2 Shapes the Mucosal Microbiome and Contributes to Inflammatory Susceptibility Open
Reactive oxygen species (ROS) are highly reactive molecules formed from diatomic oxygen. They act as cellular signals, exert antibiotic activity towards invading microorganisms, but can also damage host cells. Dual oxidase 2 (DUOX2) is the…