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View article: The downside of metabolic diversity: Postingestive rearrangements by specialized insects
The downside of metabolic diversity: Postingestive rearrangements by specialized insects Open
Significance Higher plants produce specialized metabolites to cope with biotic and abiotic challenges faced in natural environments. The diversity and complexity of specialized metabolism is often beneficial, providing functional synergism…
View article: Metabolite Ratios as Quality Indicators for Pre-Analytical Variation in Serum and EDTA Plasma
Metabolite Ratios as Quality Indicators for Pre-Analytical Variation in Serum and EDTA Plasma Open
In clinical diagnostics and research, blood samples are one of the most frequently used materials. Nevertheless, exploring the chemical composition of human plasma and serum is challenging due to the highly dynamic influence of pre-analyti…
View article: Specific decorations of 17-hydroxygeranyllinalool diterpene glycosides solve the autotoxicity problem of chemical defense in <i>Nicotiana attenuata</i>
Specific decorations of 17-hydroxygeranyllinalool diterpene glycosides solve the autotoxicity problem of chemical defense in <i>Nicotiana attenuata</i> Open
The native diploid tobacco Nicotiana attenuata produces abundant, potent anti-herbivore defense metabolites known as 17-hydroxygeranyllinalool diterpene glycosides (HGL-DTGs) whose glycosylation and malonylation biosynthetic steps are regu…
View article: Specific decorations of 17-hydroxygeranyllinalool diterpene glycosides solve the autotoxicity problem of chemical defense in<i>Nicotiana attenuata</i>
Specific decorations of 17-hydroxygeranyllinalool diterpene glycosides solve the autotoxicity problem of chemical defense in<i>Nicotiana attenuata</i> Open
17-hydroxygeranyllinalool diterpene glycosides (HGL-DTGs) are abundant and potent anti-herbivore defense metabolites in Nicotiana attenuata whose glycosylation and malonylation biosynthetic steps are regulated by jasmonate signaling. To ch…
View article: Blumenols as shoot markers of root symbiosis with arbuscular mycorrhizal fungi
Blumenols as shoot markers of root symbiosis with arbuscular mycorrhizal fungi Open
High-through-put (HTP) screening for functional arbuscular mycorrhizal fungi (AMF)-associations is challenging because roots must be excavated and colonization evaluated by transcript analysis or microscopy. Here we show that specific leaf…
View article: Author response: Blumenols as shoot markers of root symbiosis with arbuscular mycorrhizal fungi
Author response: Blumenols as shoot markers of root symbiosis with arbuscular mycorrhizal fungi Open
Article Figures and data Abstract eLife digest Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract High-through-put (HTP) screen…
View article: Illuminating a plant’s tissue-specific metabolic diversity using computational metabolomics and information theory
Illuminating a plant’s tissue-specific metabolic diversity using computational metabolomics and information theory Open
Significance Population geneticists have educated molecular biologists in how to harness the statistical power of variance arising from interindividual natural variation to elucidate gene function in plants. The metabolic differences among…
View article: Using the knowns to discover the unknowns: <scp>MS</scp>‐based dereplication uncovers structural diversity in 17‐hydroxygeranyllinalool diterpene glycoside production in the Solanaceae
Using the knowns to discover the unknowns: <span>MS</span>‐based dereplication uncovers structural diversity in 17‐hydroxygeranyllinalool diterpene glycoside production in the Solanaceae Open
Summary Exploring the diversity of plant secondary metabolism requires efficient methods to obtain sufficient structural insights to discriminate previously known from unknown metabolites. De novo structure elucidation and confirmation of …
View article: Phytochemical Investigation on Euphorbia macrostegia (Persian wood spurge).
Phytochemical Investigation on Euphorbia macrostegia (Persian wood spurge). Open
\nEuphorbia macrostegia or Persian wood spurge is one of the seventeen endemic plants of this genus in Iran. Three triterpenoids, 24-methylenecycloartan-3β-ol (1), butyrospermol (2) and cycloartenol (3) and three diglycerides, 1,2-di-O-α…