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View article: Highly Sensitive Suspension Immunoassay for Multiplex Detection, Differentiation, and Quantification of Eight Staphylococcus aureus Enterotoxins (SEA to SEI)
Highly Sensitive Suspension Immunoassay for Multiplex Detection, Differentiation, and Quantification of Eight Staphylococcus aureus Enterotoxins (SEA to SEI) Open
Staphylococcal enterotoxins (SEs) are major contributors to foodborne intoxications. Reliable detection methods for SEs are essential to maintain food safety and protect public health. Since the heat-stable toxins also exert their toxic ef…
View article: Presence and genetic variability of Staphylococcus aureus subsp. anaerobius isolated from small ruminants in Central Europe
Presence and genetic variability of Staphylococcus aureus subsp. anaerobius isolated from small ruminants in Central Europe Open
Staphylococcus aureus subsp. anaerobius (SAAN) causes abscesses in small ruminants, known as Morel’s Disease. This study describes the presence of SAAN for the first time in Germany and Austria and examines the phylogenetic relationship am…
View article: Elimination of Methicillin-Resistant Staphylococcus aureus from Mammary Glands of Dairy Cows by an Additional Antibiotic Treatment Prior to Dry Cow Treatment
Elimination of Methicillin-Resistant Staphylococcus aureus from Mammary Glands of Dairy Cows by an Additional Antibiotic Treatment Prior to Dry Cow Treatment Open
Methicillin-resistant Staphylococcus aureus (MRSA) have been isolated from quarter milk samples of dairy cows, raising concerns over transmission to consumers of raw milk. This study investigates whether pre-treatment before dry-off can in…
View article: Genomic study of European Clostridioides difficile ribotype 002/sequence type 8
Genomic study of European Clostridioides difficile ribotype 002/sequence type 8 Open
Clostridioides difficile has significant clinical importance as a leading cause of healthcare-associated infections, with symptoms ranging from mild diarrhoea to severe colitis, and possible life-threatening complications. C. difficile rib…
View article: High toxinogenic potential of Staphylococcus aureus from wild ungulates in Brandenburg, Germany with a low level of antibiotic resistance
High toxinogenic potential of Staphylococcus aureus from wild ungulates in Brandenburg, Germany with a low level of antibiotic resistance Open
Introduction Data regarding the occurrence and virulence of Staphylococcus ( S .) aureus in wild living animals is rare. However, S. aureus may carry a multitude of virulence factors and express resistance to several antimicrobial substanc…
View article: MRSA in bulk tank milk of dairy herds in Germany – changes over time
MRSA in bulk tank milk of dairy herds in Germany – changes over time Open
Objective Methicillin-resistant Staphylococcus aureus (MRSA) have repeatedly been isolated from dairy herds. It was the purpose of this study to compare the results of 3 subsequent national scale cross-sectional investigations in dairy her…
View article: D-JRP15-FED-AMR-WP2.1 FINAL REPORT
D-JRP15-FED-AMR-WP2.1 FINAL REPORT Open
OHEJP Project: FED-AMR (Final Report)
View article: Final report JRP15-AMR2.1-FED-AMR
Final report JRP15-AMR2.1-FED-AMR Open
View article: Deliverable D-JRP15–FED-AMR-WP3.2: Overview of genetic overlap between human and non-human Clostridiodes difficile isolates
Deliverable D-JRP15–FED-AMR-WP3.2: Overview of genetic overlap between human and non-human Clostridiodes difficile isolates Open
This deliverable and the associated task aims to contribute to increase knowledge regarding the true impact of C. difficile as a zoonotic agent and its transmission networks, by evaluating the extent of genetic overlap and potential transm…
View article: D-JRP15–FED-AMR-WP3.3 Deliverable 3.3 Classification of pig farm compartments according to their role in the epidemiology of Clostridioides difficile (task 3.4)
D-JRP15–FED-AMR-WP3.3 Deliverable 3.3 Classification of pig farm compartments according to their role in the epidemiology of Clostridioides difficile (task 3.4) Open
In order to assess C. difficile/AMR dissemination between humans, animals and the environment, studies were conducted on samples from 4 countries (2 HOALs Portugal, Austria, 1 agricultural facility Estonia, single compartments Ire…
View article: Plasmid-Coded Linezolid Resistance in Methicillin-Resistant Staphylococcus aureus from Food and Livestock in Germany
Plasmid-Coded Linezolid Resistance in Methicillin-Resistant Staphylococcus aureus from Food and Livestock in Germany Open
Resistance of methicillin-resistant Staphylococcus aureus (MRSA) from food and livestock to last resort antibiotics such as linezolid is highly concerning, since treatment options for infections in humans might be diminished. Known mechani…
View article: Metabolic Characteristics of Porcine LA-MRSA CC398 and CC9 Isolates from Germany and China via Biolog Phenotype MicroArrayTM
Metabolic Characteristics of Porcine LA-MRSA CC398 and CC9 Isolates from Germany and China via Biolog Phenotype MicroArrayTM Open
Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) is an important zoonotic pathogen, often multi-resistant to antimicrobial agents. Among swine, LA-MRSA of clonal complex (CC) 398 dominates in Europe, Australia and…
View article: Evaluation of the Occurrence of<i>Staphylococcaceae</i>with Reduced Susceptibility to Cefoxitin in Wild Ungulates in Brandenburg, Germany, Based on Land Use-Related Factors
Evaluation of the Occurrence of<i>Staphylococcaceae</i>with Reduced Susceptibility to Cefoxitin in Wild Ungulates in Brandenburg, Germany, Based on Land Use-Related Factors Open
Intensive research regarding the impact of land use-related factors on the prevalence and distribution of antimicrobial-resistant Staphylococcaceae in game ungulate populations is necessary for adequately determining risks related to inter…
View article: A virulence factor as a therapeutic: the probiotic <i>Enterococcus faecium</i> SF68 arginine deiminase inhibits innate immune signaling pathways
A virulence factor as a therapeutic: the probiotic <i>Enterococcus faecium</i> SF68 arginine deiminase inhibits innate immune signaling pathways Open
The probiotic bacterial strain Enterococcus faecium SF68 has been shown to alleviate symptoms of intestinal inflammation in human clinical trials and animal feed supplementation studies. To identify factors involved in immunomodulatory eff…
View article: Prevalence and diversity of Staphylococcus aureus in the Zambian dairy value chain: A public health concern
Prevalence and diversity of Staphylococcus aureus in the Zambian dairy value chain: A public health concern Open
Staphylococcus aureus is an important opportunistic pathogen of both humans and animals. It can cause several diseases, including mastitis, as well as food poisoning by production of heat-stable enterotoxins in food. The aim of this study …
View article: Mammaliicoccus spp. from German Dairy Farms Exhibit a Wide Range of Antimicrobial Resistance Genes and Non-Wildtype Phenotypes to Several Antibiotic Classes
Mammaliicoccus spp. from German Dairy Farms Exhibit a Wide Range of Antimicrobial Resistance Genes and Non-Wildtype Phenotypes to Several Antibiotic Classes Open
Mammaliicocci might play a major role in antimicrobial resistance (AMR) gene transmission between organisms of the family Staphylococcaceae, such as the potentially pathogenic species Staphylococcus aureus. The interest of this study was t…
View article: Phylogenetic Tracking of LA-MRSA ST398 Intra-Farm Transmission among Animals, Humans and the Environment on German Dairy Farms
Phylogenetic Tracking of LA-MRSA ST398 Intra-Farm Transmission among Animals, Humans and the Environment on German Dairy Farms Open
Methicillin-resistant Staphylococcus aureus (MRSA) are a major threat to human and animal health, causing difficult-to-treat infections. The aim of our study was to evaluate the intra-farm transmission of livestock-associated (LA) MRSA seq…
View article: Multidrug-resistant Staphylococcus cohnii and Staphylococcus urealyticus isolates from German dairy farms exhibit resistance to beta-lactam antibiotics and divergent penicillin-binding proteins
Multidrug-resistant Staphylococcus cohnii and Staphylococcus urealyticus isolates from German dairy farms exhibit resistance to beta-lactam antibiotics and divergent penicillin-binding proteins Open
Non- aureus staphylococci are commonly found on dairy farms. Two rarely investigated species are Staphylococcus ( S .) cohnii and S . urealyticus . Since multidrug-resistant S. cohnii and S . urealyticus are known, they may serve as an ant…
View article: Genomic Distinctions of LA-MRSA ST398 on Dairy Farms From Different German Federal States With a Low Risk of Severe Human Infections
Genomic Distinctions of LA-MRSA ST398 on Dairy Farms From Different German Federal States With a Low Risk of Severe Human Infections Open
Methicillin-resistant Staphylococcus aureus (MRSA) have been found on German dairy farms and may be the cause of difficult-to-treat bovine mastitis. Considering the one health approach, MRSA might be transmitted from animals to humans rais…
View article: Prevalence and phylogenetic relationship of Clostridioides difficile strains in fresh poultry meat samples processed in different cutting plants
Prevalence and phylogenetic relationship of Clostridioides difficile strains in fresh poultry meat samples processed in different cutting plants Open
Clostridioides difficile is one of the most frequent causes of nosocomial infections in humans leading to (antibiotic-associated) diarrhea and severe pseudomembranous colitis. With an increasing frequency, C. difficile infections (CDI) are…
View article: Antimicrobial Resistance and Virulence of Methicillin-Resistant Staphylococcus aureus from Human, Chicken and Environmental Samples within Live Bird Markets in Three Nigerian Cities
Antimicrobial Resistance and Virulence of Methicillin-Resistant Staphylococcus aureus from Human, Chicken and Environmental Samples within Live Bird Markets in Three Nigerian Cities Open
Background: Methicillin-resistant Staphylococcus aureus (MRSA) has emerged as a major threat to public health. This study investigated the occurrence of MRSA in humans, chickens, chicken meat and environmental samples within poultry farms …
View article: Quality assurance for genotyping and resistance testing of Clostridium (Clostridioides) difficile isolates - Experiences from the first inter-laboratory ring trial in four German speaking countries
Quality assurance for genotyping and resistance testing of Clostridium (Clostridioides) difficile isolates - Experiences from the first inter-laboratory ring trial in four German speaking countries Open
Clostridium (Clostridioides) difficile is a major cause of nosocomial diarrhoea. A first inter-laboratory ring trial was performed in four European countries to evaluate the genotyping and antibiotic susceptibility testing (AST) accuracy. …
View article: Broilers with low serum Mannose-binding Lectin show increased fecal shedding of Salmonella enterica serovar Montevideo
Broilers with low serum Mannose-binding Lectin show increased fecal shedding of Salmonella enterica serovar Montevideo Open
Mannose-binding lectin (MBL) is a key molecule in innate immunity. MBL binds to carbohydrates on the surface of pathogens, initiating the complement system via the lectin-dependent pathway or facilitates opsonophagocytosis. In vivo studies…
View article: Novel Immunomodulatory Flagellin-Like Protein FlaC in Campylobacter jejuni and Other <i>Campylobacterales</i>
Novel Immunomodulatory Flagellin-Like Protein FlaC in Campylobacter jejuni and Other <i>Campylobacterales</i> Open
Flagellins not only are important for bacterial motility but are major bacterial proteins that can modulate host responses via Toll-like receptor 5 (TLR5) or other pattern recognition receptors. Campylobacterales colonizing the intestinal …