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View article: Long Exhalations as Complementary Treatment for Chronic Pain: A Pilot Study
Long Exhalations as Complementary Treatment for Chronic Pain: A Pilot Study Open
Background: Chronic pain (CP) is one of the biggest burdens for health systems across the globe. It frequently presents in conjunction with comorbidities and considerable challenges for the maintenance of homeostasis and well-being. The la…
View article: Social exposome and brain health outcomes of dementia across Latin America
Social exposome and brain health outcomes of dementia across Latin America Open
A multidimensional social exposome (MSE)—the combined lifespan measures of education, food insecurity, financial status, access to healthcare, childhood experiences, and more—may shape dementia risk and brain health over the lifespan, part…
View article: Functional connectivity-targeted high-definition transcranial infraslow grey noise stimulation for chronic low back pain: protocol for a double-blinded, randomised, controlled clinical trial
Functional connectivity-targeted high-definition transcranial infraslow grey noise stimulation for chronic low back pain: protocol for a double-blinded, randomised, controlled clinical trial Open
Introduction Chronic low back pain (CLBP) is a disabling condition worldwide, with unsatisfactory treatment outcomes, warranting newer therapies. Brain imaging demonstrates altered functional connectivity among three pain processing networ…
View article: Inhibition of Cortical Evoked Responses to Sound Pulses by Preceding Silent Gaps
Inhibition of Cortical Evoked Responses to Sound Pulses by Preceding Silent Gaps Open
View article: Empirically Integrating the Evidence for Different Predictive Coding Components Using Auditory False Perception
Empirically Integrating the Evidence for Different Predictive Coding Components Using Auditory False Perception Open
Perception is a probabilistic estimation of the sensory information we receive at any given time and is shaped by an internal model generated by the brain by assimilating information over the life course. This predictive system in the brai…
View article: Transcutaneous electrical stimulation enhances episodic memory encoding via a noradrenaline-attention network, with associated neuroinflammatory changes
Transcutaneous electrical stimulation enhances episodic memory encoding via a noradrenaline-attention network, with associated neuroinflammatory changes Open
40 Hz NITESGON can activate a noradrenaline - dorsal attention network, to facilitate goal-directed attention during encoding stages of a long-term memory task, in association with neuroinflammatory changes.
View article: Neural signatures of online and offline motor learning: An ALE meta-analysis
Neural signatures of online and offline motor learning: An ALE meta-analysis Open
Neural activation patterns underlying motor learning that are captured using functional imaging can only reflect the patterns occurring at a given moment. Motor learning is known to comprise many processes which are variably biologically o…
View article: Auditory illusory models as proxies to investigate bottom-up and top-down neural networks of phantom perception
Auditory illusory models as proxies to investigate bottom-up and top-down neural networks of phantom perception Open
Auditory phantom perception, exemplified by tinnitus, is characterized by a perceptual experience without external stimuli. This study utilized two auditory illusions, the Zwicker Tone (ZT) and Conditioned Hallucinations (CH), as proxies t…
View article: Occipital nerve stimulation selectively modulates top-down inhibitory control
Occipital nerve stimulation selectively modulates top-down inhibitory control Open
View article: Comment on: Frontal HD-tACS enhances behavioral and EEG biomarkers of vigilance in continuous attention task
Comment on: Frontal HD-tACS enhances behavioral and EEG biomarkers of vigilance in continuous attention task Open
View article: An overview of the effects and mechanisms of transcranial stimulation frequency on motor learning
An overview of the effects and mechanisms of transcranial stimulation frequency on motor learning Open
Many studies over the recent decades have attempted the modulation of motor learning using brain stimulation. Alternating currents allow for researchers not only to electrically stimulate the brain, but to further investigate the effects o…
View article: The Locus Coeruleus in Chronic Pain
The Locus Coeruleus in Chronic Pain Open
Pain perception is the consequence of a complex interplay between activation and inhibition. Noradrenergic pain modulation inhibits nociceptive transmission and pain perception. The main source of norepinephrine (NE) in the central nervous…
View article: ENIGMA-Chronic Pain: a worldwide initiative to identify brain correlates of chronic pain
ENIGMA-Chronic Pain: a worldwide initiative to identify brain correlates of chronic pain Open
International audience
View article: Switching tinnitus on or off: An initial investigation into the role of the pregenual and rostral to dorsal anterior cingulate cortices
Switching tinnitus on or off: An initial investigation into the role of the pregenual and rostral to dorsal anterior cingulate cortices Open
Research indicates that hearing loss significantly contributes to tinnitus, but it alone does not fully explain its occurrence, as many people with hearing loss do not experience tinnitus. To identify a secondary factor for tinnitus genera…
View article: Chronic pain – A maladaptive compensation to unbalanced hierarchical predictive processing
Chronic pain – A maladaptive compensation to unbalanced hierarchical predictive processing Open
The ability to perceive pain presents an interesting evolutionary advantage to adapt to an ever-changing environment. However, in the case of chronic pain (CP), pain perception hinders the capacity of the system to adapt to changing sensor…
View article: Investigating sensitivity to multi-domain prediction errors in chronic auditory phantom perception
Investigating sensitivity to multi-domain prediction errors in chronic auditory phantom perception Open
View article: Development, Insults and Predisposing Factors of the Brain’s Predictive Coding System to Chronic Perceptual Disorders—A Life-Course Examination
Development, Insults and Predisposing Factors of the Brain’s Predictive Coding System to Chronic Perceptual Disorders—A Life-Course Examination Open
The predictive coding theory is currently widely accepted as the theoretical basis of perception and chronic perceptual disorders are explained as the maladaptive compensation of the brain to a prediction error. Although this gives us a ge…
View article: Let’s Shape Learning Into Lasting Memories
Let’s Shape Learning Into Lasting Memories Open
Recent experiments in rats and humans have indicated that the effects of non-invasive electrical stimulation are primarily due to transcutaneous stimulation of peripheral nerves, specifically the greater occipital nerve. This stimulation p…
View article: Feasibility of deep learning to predict tinnitus patient outcomes
Feasibility of deep learning to predict tinnitus patient outcomes Open
Advances in machine and deep learning techniques provide a novel approach in understanding complex patterns within large datasets, leading to an implementation of personalized medicine approaches to support clinical decision making. Result…
View article: The brain’s duck test in phantom percepts: multisensory congruence in chronic pain and tinnitus
The brain’s duck test in phantom percepts: multisensory congruence in chronic pain and tinnitus Open
Chronic neuropathic pain and chronic tinnitus have been likened to phantom percepts, in which a complete or partial sensory deafferentation results in a filling in of the missing information derived from memory. 150 participants, 50 with t…
View article: Author Correction: Different bimodal neuromodulation settings reduce tinnitus symptoms in a large randomized trial
Author Correction: Different bimodal neuromodulation settings reduce tinnitus symptoms in a large randomized trial Open
View article: BurstDR spinal cord stimulation rebalances pain input and pain suppression in the brain in chronic neuropathic pain
BurstDR spinal cord stimulation rebalances pain input and pain suppression in the brain in chronic neuropathic pain Open
This study suggests that chronic pain is indeed an imbalance between the ascending and descending pathways in the brain and that burst spinal cord stimulation can normalize this imbalance in the brain.
View article: Promising neurostimulation routes for targeting the hippocampus to improve episodic memory: A review
Promising neurostimulation routes for targeting the hippocampus to improve episodic memory: A review Open
This review aims to highlight modern neurostimulation approaches that are effectively activating the hippocampus and enhancing episodic memory performance. The hippocampus is a brain region known to play an essential role in episodic memor…
View article: Modulating Phonological Working Memory With Anodal High-Definition Transcranial Direct Current Stimulation to the Anterior Portion of the Supplementary Motor Area
Modulating Phonological Working Memory With Anodal High-Definition Transcranial Direct Current Stimulation to the Anterior Portion of the Supplementary Motor Area Open
Background: Phonological working memory is key to vocabulary acquisition, spoken word recognition, real-time language processing, and reading. Transcranial direct current stimulation, when coupled with behavioral training, has been shown t…
View article: Making memories last using the peripheral effect of direct current stimulation
Making memories last using the peripheral effect of direct current stimulation Open
Most memories that are formed are forgotten, while others are retained longer and are subject to memory stabilization. We show that non-invasive transcutaneous electrical stimulation of the greater occipital nerve (NITESGON) using direct c…
View article: The respective contribution of cognitive control and working memory to semantic and subjective organization in aging.
The respective contribution of cognitive control and working memory to semantic and subjective organization in aging. Open
Organizing information is beneficial to episodic memory performance. Among several possible organizational strategies, two consist of organizing the information in semantic clusters (semantic organization) or self-organizing the informatio…
View article: Tinnitus Guidelines and Their Evidence Base
Tinnitus Guidelines and Their Evidence Base Open
Evidence-based medicine (EBM) is generally accepted as the gold standard for high-quality medicine and, thus, for managing patients with tinnitus. EBM integrates the best available scientific information with clinical experience and patien…
View article: Peripheral nerve stimulation: A neuromodulation-based approach
Peripheral nerve stimulation: A neuromodulation-based approach Open
Recent technological improvements have positioned us at the threshold of innovative discoveries that will assist in new perspectives and avenues of research. Increased attention has been directed towards peripheral nerve stimulation, parti…
View article: Modulating motor learning with brain stimulation: Stage-specific perspectives for transcranial and transcutaneous delivery
Modulating motor learning with brain stimulation: Stage-specific perspectives for transcranial and transcutaneous delivery Open
Brain stimulation has been used in motor learning studies with success in improving aspects of task learning, retention, and consolidation. Using a variety of motor tasks and stimulus parameters, researchers have produced an array of liter…
View article: Corrigendum: Case report: Improving verbal retrieval deficits with high definition transcranial direct current stimulation targeting the pre-supplementary motor area in a patient with chronic traumatic brain injury
Corrigendum: Case report: Improving verbal retrieval deficits with high definition transcranial direct current stimulation targeting the pre-supplementary motor area in a patient with chronic traumatic brain injury Open
[This corrects the article DOI: 10.3389/fneur.2021.678518.].