Svenia Schmid
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View article: Single-cell RNA-sequencing of BK polyomavirus replication in primary human renal proximal tubular epithelial cells identifies specific transcriptome signatures and a novel mitochondrial stress pattern
Single-cell RNA-sequencing of BK polyomavirus replication in primary human renal proximal tubular epithelial cells identifies specific transcriptome signatures and a novel mitochondrial stress pattern Open
BK polyomavirus (BKPyV) contributes to premature renal failure in 10%–20% of kidney transplant recipients. Current treatment relies on reducing immunosuppression to regain BKPyV-specific immune control. Subsequently, declining allograft fu…
View article: Molecular control of endurance training adaptation in male mouse skeletal muscle
Molecular control of endurance training adaptation in male mouse skeletal muscle Open
Skeletal muscle has an enormous plastic potential to adapt to various external and internal perturbations. Although morphological changes in endurance-trained muscles are well described, the molecular underpinnings of training adaptation a…
View article: Molecular control of endurance training adaptation in mouse skeletal muscle
Molecular control of endurance training adaptation in mouse skeletal muscle Open
SUMMARY Skeletal muscle has an enormous plastic potential to adapt to various external and internal perturbations. While morphological changes in endurance-trained muscles are well-described, the molecular underpinnings of training adaptat…
View article: PGC-1β modulates catabolism and fiber atrophy in the fasting-response of specific skeletal muscle beds
PGC-1β modulates catabolism and fiber atrophy in the fasting-response of specific skeletal muscle beds Open