Svetlana Rachina
YOU?
Author Swipe
View article: Challenges in Diagnosing Post-COVID Pneumonia in Kazakhstan - The Role of Point-of-Care Testing: A Letter to the Editor.
Challenges in Diagnosing Post-COVID Pneumonia in Kazakhstan - The Role of Point-of-Care Testing: A Letter to the Editor. Open
Community-acquired pneumonia (CAP) remains a major public health challenge worldwide.
View article: Impact of complex interventions on antibacterial therapy and etiological diagnostics in community-acquired pneumonia: a 12-month pre- and post-intervention study
Impact of complex interventions on antibacterial therapy and etiological diagnostics in community-acquired pneumonia: a 12-month pre- and post-intervention study Open
Background Antimicrobial resistance (AMR) is a growing global health concern, with community-acquired pneumonia (CAP) remaining a leading cause of hospitalization and empirical antibiotic use. However, adherence to clinical guidelines in C…
View article: Role of procalcitonin/ferritin ratio in the differential diagnosis of viral and bacterial lung injury
Role of procalcitonin/ferritin ratio in the differential diagnosis of viral and bacterial lung injury Open
Objective. To determine role of ferritin (FT), procalcitonin (PCT) and their ratio (FT/PCT) in the differential diagnosis of viral lung injury and bacterial community-acquired pneumonia (CAP). Materials and Methods. A prospective multicent…
View article: Hypersensitivity pneumonitis: difficulties of diagnosis and occupational pathological aspects
Hypersensitivity pneumonitis: difficulties of diagnosis and occupational pathological aspects Open
Hypersensitivity pneumonitis (HP) is an interstitial lung disease characterized by an immunological reaction of the lung parenchyma in response to certain antigens in a susceptible individual. According to the literature, the prevalence of…
View article: Single-point multicenter survey of using antimicrobial drugs in the ICUs of Russian multidisciplinary hospitals: results of the Global-PPS 2022 project
Single-point multicenter survey of using antimicrobial drugs in the ICUs of Russian multidisciplinary hospitals: results of the Global-PPS 2022 project Open
Introduction. The marked increase in the resistance of infectious disease pathogens to antimicrobial drugs (AMDs), especially in intensive care units (ICUs), poses a threat to healthcare systems worldwide. This leads to adverse consequence…
View article: Antimicrobial Prescribing Patterns in Russian Outpatients in 2024: Results of the Global-PPS Project
Antimicrobial Prescribing Patterns in Russian Outpatients in 2024: Results of the Global-PPS Project Open
The pooled rates of antimicrobial prescribing in outpatient settings was 9.6% with the substantial differences in patterns of consumption overall and among the units of different types. Broad-spectrum antibacterials such as penicillin/beta…
View article: Linezolid-Resistant Coagulase-Negative Staphylococci in a Tertiary Hospital: Molecular Epidemiology, Clinical Characteristics, and Outcomes
Linezolid-Resistant Coagulase-Negative Staphylococci in a Tertiary Hospital: Molecular Epidemiology, Clinical Characteristics, and Outcomes Open
We report linezolid-resistant coagulase-negative Staphylococcus (LRCoNS) bacteremia at a tertiary hospital. LRCoNS with linezolid and tedizolid minimum inhibitory concentrations of >32 and 4-32 mg/L, respectively, were isolated from…
View article: Acute Kidney Injury as the First Manifestation of Sarcoidosis
Acute Kidney Injury as the First Manifestation of Sarcoidosis Open
We describe a case of sarcoidosis in a previously healthy 39-year-old man with the development of an acute kidney injury, requiring renal replacement therapy, as the first manifestation of the disease. The course of the disease was complic…
View article: Interleukin-6 Inhibitor Olokizumab in Hospitalized Adults with Moderate COVID-19: Results of a Single Center Observational Study
Interleukin-6 Inhibitor Olokizumab in Hospitalized Adults with Moderate COVID-19: Results of a Single Center Observational Study Open
A single-center observational study was performed to evaluate the effectiveness and safety of the interleukin-6 inhibitor olokizumab in hospitalized adults with moderate COVID-19. This study enrolled 337 patients aged from 22 to 96 years o…
View article: Comprehensive evaluation of the respiratory system, cardiovascular system, and psychoemotional disorders in post-COVID-19 adult patients
Comprehensive evaluation of the respiratory system, cardiovascular system, and psychoemotional disorders in post-COVID-19 adult patients Open
The aim was to study changes in the respiratory system, cardiovascular system, functional and psychoemotional status of adult patients after inpatient treatment for COVID-19 ( COronaVIrus Disease 2019). Methods. This cohort prospective obs…
View article: A fulminant case of <i>Streptococcus pyogenes</i> bacteremic pneumonia
A fulminant case of <i>Streptococcus pyogenes</i> bacteremic pneumonia Open
View article: Combat injuries of the lungs and pleura: an analysis of clinical cases
Combat injuries of the lungs and pleura: an analysis of clinical cases Open
Aim. To analyze the clinical cases of patients with various combat chest injuries. Materials and methods. A cross-sectional observational study enrolled 80 patients who had chest wounds in the period from 4 to 67 days (mean 23.8±12.6 days)…
View article: Features of the covid-19 epidemic and characteristics of patients during the spread of the delta SARS-COV-2 in Russia
Features of the covid-19 epidemic and characteristics of patients during the spread of the delta SARS-COV-2 in Russia Open
Aim: To study the manifestations of the COVID-19 epidemic and the clinical and epidemiological characteristics of adult patients with a new coronavirus infection during the dominance of the Delta SARS-COV-2 in the Russian Federation. Mater…
View article: Epidemiological Features of the COVID-19 and Characteristics of Patients during the Spread of the Omicron SARS-COV-2 in Russia
Epidemiological Features of the COVID-19 and Characteristics of Patients during the Spread of the Omicron SARS-COV-2 in Russia Open
Aim. To analyze dynamic of incidence and mortality of COVID-19 and clinical and epidemiological characteristics of adult patients with a new coronavirus infection during the early period of the Omicron SARS-COV-2 distribution in Russia. Ma…
View article: Community-acquired pneumonia in adults
Community-acquired pneumonia in adults Open
View article: Nosocomial pneumonia
Nosocomial pneumonia Open
View article: Hyperglycemia in patients with combat injuries
Hyperglycemia in patients with combat injuries Open
Aim. To investigate the prevalence and some aspects of the carbohydrate metabolism pathology in patients with combat limb injuries. Materials and methods. 210 patients who suffered from combat injuries of the lower and/or upper extremities…
View article: Manifestation of epidemic process, clinical and epidemiological characteristics of adult patients in the early period of the COVID-19 epidemic in Russia
Manifestation of epidemic process, clinical and epidemiological characteristics of adult patients in the early period of the COVID-19 epidemic in Russia Open
BACKGROUND: The COVID-19 pandemic became a challenge and caused significant social and economic damage to most countries. For the most objective assessment of the epidemiological and clinical features of COVID-19 during different periods o…
View article: The significance of monitoring respiratory sample cultures and polymerase chain reaction tests for detecting bacterial pathogens in severely and critically ill patients with COVID-19
The significance of monitoring respiratory sample cultures and polymerase chain reaction tests for detecting bacterial pathogens in severely and critically ill patients with COVID-19 Open
Background. Bacterial superinfection is one of the most common and potentially lethal complications in severely and critically ill patients with COVID-19. Objectives. To determine the colonisation time frame and the spectrum of potential b…
View article: The antibiotic knowledge, attitudes and behaviours of patients purchasing antibiotics with prescription in Russia: a qualitative, comparative analysis
The antibiotic knowledge, attitudes and behaviours of patients purchasing antibiotics with prescription in Russia: a qualitative, comparative analysis Open
Objectives The study aimed to investigate behaviour, knowledge and practices towards antibiotic (AB) use among patients who purchased ABs with a prescription across Russia. Methods Semi-structured interviews conducted in all eight Federal …
View article: Development of a model for the differential diagnosis of community-acquired bacterial pneumonia and viral lung injury in hospitalized adult patients
Development of a model for the differential diagnosis of community-acquired bacterial pneumonia and viral lung injury in hospitalized adult patients Open
Relevance. During and after the COVID-19 pandemic, viruses have become a more common cause of pulmonary infections in adults; therefore, the distinction between viral lung injury and community-acquired bacterial pneumonia is of increasing …
View article: Heart rhythm disturbances and blood pressure profile in patients with combat injuries
Heart rhythm disturbances and blood pressure profile in patients with combat injuries Open
Aim. To investigate possible rhythm and conduction disturbances, as well as the blood pressure (BP) profile in young and middle-aged patients with combat wounds. Materials and methods. The cross-sectional study enrolled 102 patients who su…
View article: A Case of Acute Neurologic Deficit and Hypoglycemia in the Setting of Thyroid Storm and Diabetic Ketoacidosis: A New Clinical Scenario
A Case of Acute Neurologic Deficit and Hypoglycemia in the Setting of Thyroid Storm and Diabetic Ketoacidosis: A New Clinical Scenario Open
The simultaneous development of diabetic ketoacidosis (DKA) and thyroid storm (TS) is a rare but potentially lifethreatening condition that requires immediate and targeted treatment. However, their combined diagnosis poses a serious challe…
View article: Difficulties in choosing antibacterial therapy regimen for nosocomial pneumonia in intensive care units: clinical observations
Difficulties in choosing antibacterial therapy regimen for nosocomial pneumonia in intensive care units: clinical observations Open
Nosocomial pneumonia is one of the most common healthcare-associated infections and the most frequent in intensive care unit (ICU) patients. The clinical and economic consequences of nosocomial pneumonia are very significant, especially fo…
View article: Microbial landscape of wounds in patients with combat trauma of extremities
Microbial landscape of wounds in patients with combat trauma of extremities Open
Objective. To analyze the profile of bacterial pathogens in patients with extremities wounds resulting from mine-blast injuries, and their susceptibility to antibacterial drugs. Materials and methods. The prospective observational study en…
View article: Ceftobiprole medocaril: clinical and pharmacological characteristics and possibilities of clinical use
Ceftobiprole medocaril: clinical and pharmacological characteristics and possibilities of clinical use Open
Ceftobiprole medocaril is a fifth-generation cephalosporin (anti-MRSA cephem) with a broad spectrum of antibacterial activity. Ceftobiprole is active against gram-positive bacteria, including strains resistant to other beta-lactams, such a…
View article: Etiology of community-acquired pneumonia in adults in Russian hospitals after the COVID-19 pandemic: results of a multicenter prospective study
Etiology of community-acquired pneumonia in adults in Russian hospitals after the COVID-19 pandemic: results of a multicenter prospective study Open
Objective. To study the etiology of community-acquired pneumonia (CAP) in adult hospitalized patients after the COVID-19 pandemic. Materials and Methods. The prospective multicenter study included patients 18 years and older with confirmed…
View article: A Rare Case of Secondary Systemic Amyloidosis in a Young Patient with Crohn's Disease: A Case Report
A Rare Case of Secondary Systemic Amyloidosis in a Young Patient with Crohn's Disease: A Case Report Open
View article: A rare case of cardiac and ophthalmic manifestations of meningococcal septicemia
A rare case of cardiac and ophthalmic manifestations of meningococcal septicemia Open
View article: Diagnosis and antibiotic therapy of nosocomial pneumonia in adults: from recommendations to real practice. A review
Diagnosis and antibiotic therapy of nosocomial pneumonia in adults: from recommendations to real practice. A review Open
Nosocomial pneumonia is a healthcare-associated infection with significant consequences for the patient and the healthcare system. The efficacy of treatment significantly depends on the timeliness and adequacy of the antibiotic therapy reg…