Swati Arya
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View article: Properties of the major Zn<sup>2+</sup>-binding site of human alpha-fetoprotein, a potential foetal plasma zinc carrier
Properties of the major Zn<sup>2+</sup>-binding site of human alpha-fetoprotein, a potential foetal plasma zinc carrier Open
The foetal plasma protein alpha-fetoprotein harbours a strong Zn 2+ binding site ( K D = 1.9 × 10 −8 M), supporting the hypothesis of a role in foetal zinc homeostasis.
View article: Optimised plasma sample preparation and LC‐MS analysis to support large‐scale proteomic analysis of clinical trial specimens: Application to the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) trial
Optimised plasma sample preparation and LC‐MS analysis to support large‐scale proteomic analysis of clinical trial specimens: Application to the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) trial Open
Purpose Robust, affordable plasma proteomic biomarker workflows are needed for large‐scale clinical studies. We evaluated aspects of sample preparation to allow liquid chromatography‐mass spectrometry (LC‐MS) analysis of more than 1500 sam…
View article: A critical analysis of Madanpal Nighantu – An ancient lexicon of Ayurvedic literature
A critical analysis of Madanpal Nighantu – An ancient lexicon of Ayurvedic literature Open
Since ancient times, there is a tradition of composition of lexicons in Ayurveda, which are called Nighantu. The Ayurvedic physicians who do not know the names of drugs, they become suspicious and do not recognize the medicine even after s…
View article: Structural and biochemical characterisation of Co<sup>2+</sup>-binding sites on serum albumins and their interplay with fatty acids
Structural and biochemical characterisation of Co<sup>2+</sup>-binding sites on serum albumins and their interplay with fatty acids Open
Serum albumin–Co 2+ interactions are of clinical importance.
View article: Identification of plasma proteins associated with oesophageal cancer chemotherapeutic treatment outcomes using SWATH-MS
Identification of plasma proteins associated with oesophageal cancer chemotherapeutic treatment outcomes using SWATH-MS Open
Oesophageal adenocarcinoma (OAC) is an aggressive cancer with a five-year survival of <15%. Current chemotherapeutic strategies only benefit a minority (20-30%) of patients and there are no methods available to differentiate between respon…
View article: Fatty acids may influence insulin dynamics through modulation of albumin‐Zn<sup>2+</sup> interactions
Fatty acids may influence insulin dynamics through modulation of albumin‐Zn<sup>2+</sup> interactions Open
Insulin is stored within the pancreas in an inactive Zn 2+ ‐bound hexameric form prior to release. Similarly, clinical insulins contain Zn 2+ and form multimeric complexes. Upon release from the pancreas or upon injection, insulin only bec…
View article: Leptin and Obesity: Role and Clinical Implication
Leptin and Obesity: Role and Clinical Implication Open
The peptide hormone leptin regulates food intake, body mass, and reproductive function and plays a role in fetal growth, proinflammatory immune responses, angiogenesis and lipolysis. Leptin is a product of the obese ( ob ) gene and, follow…
View article: Pulse Dipolar EPR Reveals Double-Histidine Motif Cu <sup>II</sup> –NTA Spin-Labeling Robustness against Competitor Ions
Pulse Dipolar EPR Reveals Double-Histidine Motif Cu <sup>II</sup> –NTA Spin-Labeling Robustness against Competitor Ions Open
Pulse-dipolar EPR is an appealing strategy for structural characterization of complex systems in solution that complements other biophysical techniques. Significantly, the emergence of genetically encoded self-assembling spin labels exploi…
View article: Pulse Dipolar EPR Reveals Double-Histidine Motif Spin-labelling is Robust Against Competitor Ions
Pulse Dipolar EPR Reveals Double-Histidine Motif Spin-labelling is Robust Against Competitor Ions Open
Pulse-dipolar EPR is an appealing strategy for structural characterization of complex systems in solution that complements other biophysical techniques. Significantly, the emergence of genetically encoded self-assembling spin labels exploi…
View article: Pulse Dipolar EPR Reveals Double-Histidine Motif Spin-labelling is Robust Against Competitor Ions
Pulse Dipolar EPR Reveals Double-Histidine Motif Spin-labelling is Robust Against Competitor Ions Open
Pulse-dipolar EPR is an appealing strategy for structural characterization of complex systems in solution that complements other biophysical techniques. Significantly, the emergence of genetically encoded self-assembling spin labels exploi…
View article: Accidental injection of lignocaine with adrenaline in subarachnoid space: a case report
Accidental injection of lignocaine with adrenaline in subarachnoid space: a case report Open
Drug errors are very common in medical field especially in anaesthesia where it’s the game of drugs. Here, we are presenting a case in which accidentally we injected lignocaine with adrenaline in place of heavy bupivacaine. Patient was of …
View article: Accidental extubation during parotid surgery: An unusual but dreaded complication
Accidental extubation during parotid surgery: An unusual but dreaded complication Open
Sir, Accidental extubation is one of the important complications of airway management during general anaesthesia especially during head and neck surgery that requires urgent intervention to secure the airway. We witnessed a case of acciden…
View article: Why Map the MAPCAs? : Heart to heart with a cardiac surgeon’
Why Map the MAPCAs? : Heart to heart with a cardiac surgeon’ Open
Poster: ECR 2018 / C-0936 / Why Map the MAPCAs? : Heart to heart with a cardiac surgeon’ by: P. Narang 1, S. Arya2, A. K. Verma3, N. Goyal 4, D. S. Agarawal4; 1DELHI, DELHI/IN, 2Delhi/IN, 3New Delhi, Delhi/IN, 4New Delhi/IN
View article: Epistaxis as the initial presentation in a case of rheumatic heart disease
Epistaxis as the initial presentation in a case of rheumatic heart disease Open
Rheumatic heart disease (RHD) remains prevalent in developing nations and shows varied presentations, causing diagnostic challenge. Here, we report a case of RHD in a 13-year-old boy who presented with recurrent epistaxis as the initial sy…
View article: Identifying the hydroxyapatite interactome: Involvement of serum proteins in the formation of sub-RPE deposits
Identifying the hydroxyapatite interactome: Involvement of serum proteins in the formation of sub-RPE deposits Open
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.
View article: Cardiovascular health in women: The role of diet
Cardiovascular health in women: The role of diet Open
The prevalence of cardiovascular diseases (CVDs) has been increasing over the years and is one of the leading causes of deaths in the Indian population. While women may have a lower risk of CVD, as compared to men, during the early phases …