Swati Basu
YOU?
Author Swipe
View article: Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice
Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice Open
Anthracycline‐induced cardiotoxicity remains a major limitation in cancer therapy, affecting long‐term cardiovascular health in survivors. Dietary nitrate supplementation has shown cardioprotective effects in preclinical models of doxorubi…
View article: Dietary nitrate and nitrite protect against doxorubicin-induced cardiac fibrosis and oxidative protein damage in tumor-bearing mice
Dietary nitrate and nitrite protect against doxorubicin-induced cardiac fibrosis and oxidative protein damage in tumor-bearing mice Open
Anthracycline-induced cardiotoxicity remains a major limitation in cancer therapy, affecting long-term cardiovascular health in survivors. Dietary nitrate supplementation has shown cardioprotective effects in preclinical models of doxorubi…
View article: Rainbow of hemolysis associated with acquired thrombotic thrombocytopenic purpura
Rainbow of hemolysis associated with acquired thrombotic thrombocytopenic purpura Open
Acquired thrombotic thrombocytopenic purpura (TTP) is a rare disease characterized by thrombocytopenia and microangiopathic hemolytic anemia. Autoantibodies directed against the von Willebrand Factor (vWF)-cleaving enzyme, ADAMTS13, result…
View article: Effects of short-term dietary nitrate supplementation on exercise and coronary blood flow responses in patients with peripheral artery disease
Effects of short-term dietary nitrate supplementation on exercise and coronary blood flow responses in patients with peripheral artery disease Open
Background Peripheral arterial disease (PAD) is a prevalent vascular disorder characterized by atherosclerotic occlusion of peripheral arteries, resulting in reduced blood flow to the lower extremities and poor walking ability. Older patie…
View article: Risk Factors of Impediment of the Early Childhood Development in Rural Bengal
Risk Factors of Impediment of the Early Childhood Development in Rural Bengal Open
Background: Early childhood development (ECD) is the foundation of future life starting from conception and depends on biological and environmental factors. Seventy-four percent of these children reside in villages; many are underserved an…
View article: Formation and signaling by an NO-ferroheme complex provides a novel pathway for intravascular and intracellular NO signaling
Formation and signaling by an NO-ferroheme complex provides a novel pathway for intravascular and intracellular NO signaling Open
Nitric oxide (NO) regulates vascular function through the activation of soluble guanylate cyclase in vascular smooth muscle and platelets. NO signaling is mediated by paracrine diffusion from endothelial cells to smooth muscle. Many questi…
View article: Thiol-catalyzed formation of NO-ferroheme regulates intravascular NO signaling
Thiol-catalyzed formation of NO-ferroheme regulates intravascular NO signaling Open
View article: Study Of Changes in Knowledge, Skill and Attitude in Parents with a Community-Based Interactive Program on ECD Promotion in Rural India
Study Of Changes in Knowledge, Skill and Attitude in Parents with a Community-Based Interactive Program on ECD Promotion in Rural India Open
Introduction: Early childhood is the period of most rapid brain development. Early childhood development (ECD) is considered a prime investment for future prosperity in all dimensions, and the nurturing care framework provides a roadmap fo…
View article: Surgical site infection: Clinico- bacteriological Profile and antibiogram in a tertiary care hospital in Kolkata
Surgical site infection: Clinico- bacteriological Profile and antibiogram in a tertiary care hospital in Kolkata Open
Introduction: Surgical site infections (SSIs) are a major health care associated infections and possess a great challenge to clinicians. It increases duration of hospital stay, associated morbidity and mortality and treatment cost. For pro…
View article: Thiol catalyzed formation of NO-ferroheme regulates canonical intravascular NO signaling
Thiol catalyzed formation of NO-ferroheme regulates canonical intravascular NO signaling Open
Nitric oxide (NO) is an endogenously produced physiological signaling molecule that regulates blood flow and platelet activation. However, both the intracellular and intravascular diffusion of NO is severely limited by scavenging reactions…
View article: Efficacy and Variability in Plasma Nitrite Levels during Long-Term Supplementation with Nitrate Containing Beetroot Juice
Efficacy and Variability in Plasma Nitrite Levels during Long-Term Supplementation with Nitrate Containing Beetroot Juice Open
Long-term consumption of beetroot juice on efficacy of converting dietary nitrate to plasma nitrate and nitrite was investigated. Adults were randomized to consume either beetroot juice with 380 mg of nitrate (BR) or a beetroot juice place…
View article: Effect of Vitamin C and Protein Supplementation on Plasma Nitrate and Nitrite Response following Consumption of Beetroot Juice
Effect of Vitamin C and Protein Supplementation on Plasma Nitrate and Nitrite Response following Consumption of Beetroot Juice Open
Beetroot juice is a food high in nitrate and is associated with cardiometabolic health benefits and enhanced exercise performance through the production of nitric oxide in the nitrate–nitrite–nitric oxide pathway. Since various food compon…
View article: Mycobacterium tuberculosis DosS binds H2S through its Fe3+ heme iron to regulate the DosR dormancy regulon
Mycobacterium tuberculosis DosS binds H2S through its Fe3+ heme iron to regulate the DosR dormancy regulon Open
View article: A single dose of dietary nitrate supplementation protects against endothelial ischemia–reperfusion injury in early postmenopausal women
A single dose of dietary nitrate supplementation protects against endothelial ischemia–reperfusion injury in early postmenopausal women Open
The onset of menopause and accompanying changes to ovarian hormones often precedes endothelial dysfunction in women. In particular, accelerated impairments in macrovascular and microvascular function coincide with the loss of estrogen, as …
View article: Inorganic nitrate supplementation and blood flow restricted exercise tolerance in post-menopausal women
Inorganic nitrate supplementation and blood flow restricted exercise tolerance in post-menopausal women Open
View article: Tri-iodide and vanadium chloride based chemiluminescent methods for quantification of nitrogen oxides
Tri-iodide and vanadium chloride based chemiluminescent methods for quantification of nitrogen oxides Open
View article: <i>Mycobacterium tuberculosis</i> DosS binds H<sub>2</sub>S through its Fe<sup>3+</sup> heme iron to regulate the Dos dormancy regulon
<i>Mycobacterium tuberculosis</i> DosS binds H<sub>2</sub>S through its Fe<sup>3+</sup> heme iron to regulate the Dos dormancy regulon Open
Mycobacterium tuberculosis ( Mtb ) senses and responds to host-derived gasotransmitters NO and CO via heme-containing sensor kinases DosS and DosT and the response regulator DosR. Hydrogen sulfide (H 2 S) is an important signaling molecule…
View article: Mechanistic insights into cell-free hemoglobin-induced injury during septic shock
Mechanistic insights into cell-free hemoglobin-induced injury during septic shock Open
Cell-free hemoglobin (CFH) elevations are a known consequence of clinical sepsis. Using a two-by-two factorial design and extensive physiological and biochemical evidence, we found a direct mechanism of injury related to nitric oxide scave…
View article: Comparative Study about Impact of Inadequate Psychomotor Stimulation on Neuro-Development in Pre-School Children in Rural India
Comparative Study about Impact of Inadequate Psychomotor Stimulation on Neuro-Development in Pre-School Children in Rural India Open
Introduction: In a rural, underprivileged community, multiple factors including poverty, non-stimulating home environment and lack of parental awareness about early childhood development and early intervention lead to inadequate ‘nurturing…
View article: Correction: A randomized controlled trial of nitrate supplementation in well-trained middle and older-aged adults
Correction: A randomized controlled trial of nitrate supplementation in well-trained middle and older-aged adults Open
[This corrects the article DOI: 10.1371/journal.pone.0235047.].
View article: A randomized controlled trial of nitrate supplementation in well-trained middle and older-aged adults
A randomized controlled trial of nitrate supplementation in well-trained middle and older-aged adults Open
In middle to older-aged well-trained adults, NO3- supplementation has non-significant, albeit highly variable, effects on exercise tolerance. ClinicalTrials.gov Identifier: NCT03371966.
View article: Cell-Free Hemoglobin Challenge Worsens Lung Injury in Experimental Canine Staphylococcus Aureus Pneumonia Inducing Septic Shock
Cell-Free Hemoglobin Challenge Worsens Lung Injury in Experimental Canine Staphylococcus Aureus Pneumonia Inducing Septic Shock Open
View article: Haptoglobin therapy has differential effects depending on severity of canine septic shock and cell‐free hemoglobin level
Haptoglobin therapy has differential effects depending on severity of canine septic shock and cell‐free hemoglobin level Open
BACKGROUND During sepsis, higher plasma cell‐free hemoglobin (CFH) levels portend worse outcomes. In sepsis models, plasma proteins that bind CFH improve survival. In our canine antibiotic‐treated Staphylococcus aureus pneumonia model, wit…
View article: Development of India’s first integrated expert urban flood forecasting system for Chennai
Development of India’s first integrated expert urban flood forecasting system for Chennai Open
Floods are the most common and recurring natural hazards faced by humans since time immemorial. They pose a severe threat to the population, environment and economy in many places across the world, especially urban areas. Urbanization caus…
View article: Development of Zinc Chelating Resin Polymer Beads for the Removal of Cell-Free Hemoglobin
Development of Zinc Chelating Resin Polymer Beads for the Removal of Cell-Free Hemoglobin Open
View article: Erythrocytic bioactivation of nitrite and its potentiation by far-red light
Erythrocytic bioactivation of nitrite and its potentiation by far-red light Open
BACKGROUND: Nitrite is reduced by heme-proteins and molybdenum-containing enzymes to form the important signaling molecule nitric oxide (NO), mediating NO signaling. Substantial evidence suggests that deoxygenated hemoglobin within red blo…
View article: Impact of different standard red blood cell storage temperatures on human and canine RBC hemolysis and chromium survival
Impact of different standard red blood cell storage temperatures on human and canine RBC hemolysis and chromium survival Open
BACKGROUND Storage temperature is a critical factor for maintaining red‐blood cell (RBC) viability, especially during prolonged cold storage. The target range of 1 to 6°C was established decades ago and may no longer be optimal for current…
View article: Effects of supervised exercise and dietary nitrate in older adults with controlled hypertension and/or heart failure with preserved ejection fraction
Effects of supervised exercise and dietary nitrate in older adults with controlled hypertension and/or heart failure with preserved ejection fraction Open
View article: Potential therapeutic action of nitrite in sickle cell disease
Potential therapeutic action of nitrite in sickle cell disease Open
View article: Beet Root Juice: An Ergogenic Aid for Exercise and the Aging Brain
Beet Root Juice: An Ergogenic Aid for Exercise and the Aging Brain Open
Older adults who exercised and consumed BRJ demonstrated greater consistency within the motor community and fewer secondary connections with the insular cortex compared with those who exercised without BRJ. The exercise + BRJ group had bra…