Swati Malik
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View article: Exploring the Therapeutic Impact of Phytoestrogen Bavachin in Rheumatoid Arthritis: Insights from Synovial Fibroblasts and Collagen Induced Arthritis Rat Model
Exploring the Therapeutic Impact of Phytoestrogen Bavachin in Rheumatoid Arthritis: Insights from Synovial Fibroblasts and Collagen Induced Arthritis Rat Model Open
View article: Integrative metabolomic-proteomic analysis uncovers a new therapeutic approach in targeting rheumatoid arthritis
Integrative metabolomic-proteomic analysis uncovers a new therapeutic approach in targeting rheumatoid arthritis Open
View article: Pathogenic Mechanisms of Collagen TypeⅦA1 (COL7A1) and Transporter Protein Transport and Golgi Organization 1 (TANGO1) in Rheumatoid Arthritis: A New Therapeutic Target
Pathogenic Mechanisms of Collagen TypeⅦA1 (COL7A1) and Transporter Protein Transport and Golgi Organization 1 (TANGO1) in Rheumatoid Arthritis: A New Therapeutic Target Open
Rheumatoid arthritis (RA) is an autoimmune disorder causing chronic inflammation primarily due to collagen regulation and transport imbalances. Collagen VII A1(COL7A1), a major component of anchoring fibrils, regulates inflammation via int…
View article: Alpha-Taxilin: A Potential Diagnosis and Therapeutics Target in Rheumatoid Arthritis Which Interacts with Key Glycolytic Enzymes Associated with Metabolic Shifts in Fibroblast-Like Synoviocytes
Alpha-Taxilin: A Potential Diagnosis and Therapeutics Target in Rheumatoid Arthritis Which Interacts with Key Glycolytic Enzymes Associated with Metabolic Shifts in Fibroblast-Like Synoviocytes Open
α-Taxilin has been found to be associated with glycolysis and gluconeogenesis. This may lead to a metabolic shift in synovial cells, ROS generation, and TLR activation. Therefore, α-Taxilin can be targeted for its diagnostic and therapeuti…
View article: Integrative Metabolomic-Proteomic Analysis Uncovers a New Therapeutic Approach in Targeting Rheumatoid Arthritis
Integrative Metabolomic-Proteomic Analysis Uncovers a New Therapeutic Approach in Targeting Rheumatoid Arthritis Open
Objective: Rheumatoid arthritis (RA) is a chronic inflammatory condition that, despite available approaches to manage the disease, lacks an efficient treatment and timely diagnosis. Using the most advanced omics technique, metabolomics and…
View article: Clo-miR-14: a medicinally valued spice-derived miRNA with therapeutic implications in rheumatoid arthritis
Clo-miR-14: a medicinally valued spice-derived miRNA with therapeutic implications in rheumatoid arthritis Open
Plant microRNAs (miRNA) are regularly consumed orally along with diet, gaining attention for their RNA-based drug potential because of their ability to regulate mammalian gene expression specifically at the post-transcriptional level. Medi…
View article: Chronic disease management via modulation of cellular signaling by phytoestrogen Bavachin
Chronic disease management via modulation of cellular signaling by phytoestrogen Bavachin Open
The emergence of chronic diseases, particularly cancers, cardiovascular, and bone disorders, presents a formidable challenge, as currently available synthetic drugs often result in significant side effects and incur higher costs. Phytoestr…
View article: Unveiling the Nexus: Cellular Metabolomics Unravels the Impact of Estrogen on Nicotinamide Metabolism in Mitigating Rheumatoid Arthritis Pathogenesis
Unveiling the Nexus: Cellular Metabolomics Unravels the Impact of Estrogen on Nicotinamide Metabolism in Mitigating Rheumatoid Arthritis Pathogenesis Open
Rheumatoid arthritis (RA) is a metabolic joint disorder influenced by hormonal regulation, notably estrogen, which plays a cytoprotective role against inflammation. While estrogen’s impact on RA pathogenesis has been studied, the altered m…
View article: Functional Significance of miR-4693-5p in Targeting HIF1α and Its Link to Rheumatoid Arthritis Pathogenesis
Functional Significance of miR-4693-5p in Targeting HIF1α and Its Link to Rheumatoid Arthritis Pathogenesis Open
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that causes joint inflammation and destruction with an unknown origin. Our study aims to elucidate the molecular mechanism behind HIF1α overexpression in RA. Dysregulat…
View article: Bibliometric Mapping of Trends, Applications and Challenges of Artificial Intelligence in Smart Cities
Bibliometric Mapping of Trends, Applications and Challenges of Artificial Intelligence in Smart Cities Open
INTRODUCTION: The continued growth of urbanization presents new challenges. This, in turn, will lead to pressure for sustainable environment initiatives, with demands for more and better infrastructure in the diminishing space available an…
View article: Intelligent Load-Balancing Framework for Fog-Enabled Communication in Healthcare
Intelligent Load-Balancing Framework for Fog-Enabled Communication in Healthcare Open
The present technological era significantly makes use of Internet-of-Things (IoT) devices for offering and implementing healthcare services. Post COVID-19, the future of the healthcare system is highly reliant upon the inculcation of Artif…
View article: Smart City: A new phase of sustainable development using fog computing and IoT
Smart City: A new phase of sustainable development using fog computing and IoT Open
Fog computing is a distributed technology which performs computations at the edge of the network. IoT devices are generating large amount of data that too Heterogeneous in nature. In order to handle applications which, require time sensiti…