Syed Shahzaib Raza
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View article: Human CD33 deficiency is associated with mild alteration of circulating white blood cell counts
Human CD33 deficiency is associated with mild alteration of circulating white blood cell counts Open
The single pass transmembrane protein CD33 is enriched in phagocytic and hematopoietic cell types, such as monocytes. CD33 is thought to be associated with immune cell function, susceptibility to Alzheimer’s disease, and rare leukemias. An…
View article: Identification and characterization of human GDF15 knockouts
Identification and characterization of human GDF15 knockouts Open
Growth differentiation factor 15 (GDF15) is a secreted protein that regulates food intake, body weight, and stress responses in pre-clinical models 1 . The physiological function of GDF15 in humans remains unclear. Pharmacologically, GDF15…