Syed Usman Hamdani
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View article: The green healer: an updated review on the phytochemical profile and therapeutic potential of Aloe vera
The green healer: an updated review on the phytochemical profile and therapeutic potential of Aloe vera Open
Aloe vera has historically been recognized as a versatile medicinal plant, attributable to its extensive array of therapeutic properties. Recent scientific research has shown a diverse variety of bioactive compounds in Aloe vera that contr…
View article: Involving young people with lived experience in advancing mental health science: an exploratory qualitative study from Pakistan and India
Involving young people with lived experience in advancing mental health science: an exploratory qualitative study from Pakistan and India Open
View article: The development of a World Health Organization transdiagnostic chatbot intervention for distressed adolescents and young adults
The development of a World Health Organization transdiagnostic chatbot intervention for distressed adolescents and young adults Open
Background Common mental disorders are prevalent in young people in low- and middle-income countries (LMICs). Digitally delivered interventions have the potential to overcome many structural and psychosocial barriers to mental health care.…
View article: Frequency of Relapse Rate after Treatment of Patients Addicted with Drugs Abuse (Opioids)
Frequency of Relapse Rate after Treatment of Patients Addicted with Drugs Abuse (Opioids) Open
Objectives: frequency of relapse rate after treatment of patients addicted with drugs abuse (Opioids). Methodology: This descriptive study at CMH Lahore included 60 patients aged 18–60 years with a history of opioid addiction. Data on demo…
View article: Effectiveness of a group psychological intervention to reduce psychosocial distress in adolescents in Pakistan: a single-blind, cluster randomised controlled trial
Effectiveness of a group psychological intervention to reduce psychosocial distress in adolescents in Pakistan: a single-blind, cluster randomised controlled trial Open
View article: Tipping the scales for global mental health: A summary of the Presidential Panel at the 39th Annual Meeting of the International Society for Traumatic Stress Studies
Tipping the scales for global mental health: A summary of the Presidential Panel at the 39th Annual Meeting of the International Society for Traumatic Stress Studies Open
In the past decade, there has been an increasing focus within scientific research on how to assist people affected by the negative consequences of trauma and crises around the globe. As many countries struggle with a lack of resources to d…
View article: The effectiveness of Technology-assisted Cascade Training and Supervision of community health workers in delivering the Thinking Healthy Program for perinatal depression in a post-conflict area of Pakistan - study protocol for a randomized controlled trial
The effectiveness of Technology-assisted Cascade Training and Supervision of community health workers in delivering the Thinking Healthy Program for perinatal depression in a post-conflict area of Pakistan - study protocol for a randomized controlled trial Open
Background: Rates of perinatal depression in low and middle income countries are reported to be very high. Perinatal depression not only has profound impact on women's health, disability and functioning, it is associated with poor child he…
View article: PREVIDA- IMPACT OF VORTIOXETINE ON MAJOR DEPRESSIVE DISORDER AND PERCEIVED COGNITIVE DYSFUNCTION: A MULTICENTER STUDY
PREVIDA- IMPACT OF VORTIOXETINE ON MAJOR DEPRESSIVE DISORDER AND PERCEIVED COGNITIVE DYSFUNCTION: A MULTICENTER STUDY Open
Objective: To find out how common cognitive impairment is in people with major depressive disorder (MDD) and assess how well vortioxetine works for treating both cognitive dysfunction and depressive symptoms. Study Design: Multi-centred, C…
View article: Boys don’t cry? Views of young people with lived experience of mental health problems from Pakistan and India: An exploratory qualitative study
Boys don’t cry? Views of young people with lived experience of mental health problems from Pakistan and India: An exploratory qualitative study Open
Background Meaningful involvement of young People with Lived Experience (PWLE) in co-designing youth mental health interventions has been much emphasized globally. However, there is a scarcity of evidence on involving PWLE of mental health…
View article: Effectiveness of a Group Psychological Intervention to Reduce Psychosocial Distress in Adolescents in Pakistan: A Single-Blind, Cluster Randomized Controlled Trial
Effectiveness of a Group Psychological Intervention to Reduce Psychosocial Distress in Adolescents in Pakistan: A Single-Blind, Cluster Randomized Controlled Trial Open
View article: Technology-assisted task-sharing to bridge the treatment gap for childhood developmental disorders in rural Pakistan: an implementation science case study
Technology-assisted task-sharing to bridge the treatment gap for childhood developmental disorders in rural Pakistan: an implementation science case study Open
View article: Improving psychosocial distress for young adolescents in rural schools of Pakistan: study protocol of a cluster randomised controlled trial
Improving psychosocial distress for young adolescents in rural schools of Pakistan: study protocol of a cluster randomised controlled trial Open
Introduction Emotional problems are leading contributors to health burden among adolescents worldwide. There is an urgent need for evidence-based psychological interventions for young people. This study aims to evaluate the effectiveness o…
View article: Effectiveness of relaxation techniques ‘as an active ingredient of psychological interventions’ to reduce distress, anxiety and depression in adolescents: a systematic review and meta-analysis
Effectiveness of relaxation techniques ‘as an active ingredient of psychological interventions’ to reduce distress, anxiety and depression in adolescents: a systematic review and meta-analysis Open
View article: Feasibility and acceptability of a multicomponent, group psychological intervention for adolescents with psychosocial distress in public schools of Pakistan: a feasibility cluster randomized controlled trial (cRCT)
Feasibility and acceptability of a multicomponent, group psychological intervention for adolescents with psychosocial distress in public schools of Pakistan: a feasibility cluster randomized controlled trial (cRCT) Open
View article: Psychometric performance of the Mental Health Implementation Science Tools (mhIST) across six low- and middle-income countries
Psychometric performance of the Mental Health Implementation Science Tools (mhIST) across six low- and middle-income countries Open
View article: Feasibility and acceptability of a multicomponent, group psychological intervention for adolescents with psychosocial distress in public schools of Pakistan: A feasibility cluster randomized controlled trial (cRCT)
Feasibility and acceptability of a multicomponent, group psychological intervention for adolescents with psychosocial distress in public schools of Pakistan: A feasibility cluster randomized controlled trial (cRCT) Open
Background Child and adolescent mental health problems are a global public mental health priority. However, there is a lack of evidence-based scalable psychological interventions for adolescents living in low resource settings. This trial …
View article: Technology Assisted Task-sharing to Bridge the Treatment Gap for Childhood Developmental Disorders in Rural Pakistan: an Implementation Science Case Study
Technology Assisted Task-sharing to Bridge the Treatment Gap for Childhood Developmental Disorders in Rural Pakistan: an Implementation Science Case Study Open
Background: As in many low-income countries, the treatment gap for developmental disorders in Pakistan is near 100%. The World Health Organization (WHO) has developed the mental Health Gap Intervention guide (mhGAP-IG) to train non-special…
View article: Effectiveness of Relaxation Techniques ‘as an Active Ingredient of Psychological Interventions’ to Reduce Distress, Anxiety and Depression in Adolescents: A Systematic Review and Meta-Analysis
Effectiveness of Relaxation Techniques ‘as an Active Ingredient of Psychological Interventions’ to Reduce Distress, Anxiety and Depression in Adolescents: A Systematic Review and Meta-Analysis Open
Background Adolescent depression and anxiety are the leading contributors to health burden worldwide. ‘Relaxation Techniques (RTs)’ are a “set of strategies to improve physiological response to stress” and are frequently cited as an active…
View article: Psychometric performance of the Mental Health Implementation Science Tools (mhIST) across six low- and middle-income countries
Psychometric performance of the Mental Health Implementation Science Tools (mhIST) across six low- and middle-income countries Open
Background Existing implementation measures developed in high-income countries may have limited appropriateness for use within low- and middle-income countries (LMIC). In response, researchers at Johns Hopkins University began developing t…
View article: Sustainable Technology for Adolescents and youth to Reduce Stress (<scp>STARS</scp>): a <scp>WHO</scp> transdiagnostic chatbot for distressed youth
Sustainable Technology for Adolescents and youth to Reduce Stress (<span>STARS</span>): a <span>WHO</span> transdiagnostic chatbot for distressed youth Open
View article: A comparison of real-world effectiveness of vortioxetine along the treatment algorithm for major depressive disorder
A comparison of real-world effectiveness of vortioxetine along the treatment algorithm for major depressive disorder Open
To evaluate the effectiveness of vortioxetine in major depressive disorder (MDD) when used as a first-line versus second-line treatment or later. This was a post-hoc analysis of three 3-month non-interventional, prospective studies of vort…
View article: Psychometric Performance of the Mental Health Implementation Science Tools (mhIST) Across Six Low- and Middle-income Countries
Psychometric Performance of the Mental Health Implementation Science Tools (mhIST) Across Six Low- and Middle-income Countries Open
Background Existing implementation measures developed in high-income countries may have limited appropriateness for use within low- and middle-income countries (LMIC). In response, researchers at Johns Hopkins University began developing t…
View article: Residual posttraumatic stress disorder symptoms after provision of brief behavioral intervention in low‐ and middle‐income countries: An individual‐patient data meta‐analysis
Residual posttraumatic stress disorder symptoms after provision of brief behavioral intervention in low‐ and middle‐income countries: An individual‐patient data meta‐analysis Open
PM+ led to greater reduction in symptoms relating to re-experiencing and avoidance. The evidence indicates that strategies focusing on hyperarousal symptoms including sleep, concentration, and anger difficulties, could be strengthened in t…
View article: SUICIDAL IDEATION IN DEPRESSED PATIENTS AND THERAPEUTIC ROLE OF VORTIOXETINE: SECONDARY ANALYSIS OF A LARGE PROSPECTIVE STUDY
SUICIDAL IDEATION IN DEPRESSED PATIENTS AND THERAPEUTIC ROLE OF VORTIOXETINE: SECONDARY ANALYSIS OF A LARGE PROSPECTIVE STUDY Open
OBJECTIVES To explore the association of different variables with suicidal ideation and the role of vortioxetine in managing suicidal ideation in depressed patients in Pakistan. STUDY DESIGN This is a secondary analysis of a large, multi-c…
View article: Evaluating the impact of a common elements-based intervention to improve maternal psychological well-being and mother–infant interaction in rural Pakistan: study protocol for a randomised controlled trial
Evaluating the impact of a common elements-based intervention to improve maternal psychological well-being and mother–infant interaction in rural Pakistan: study protocol for a randomised controlled trial Open
Introduction Millions of children in low resource settings are at high risk of poor development due to factors such as under nutrition, inadequate stimulation and maternal depression. Evidence-based interventions to address these risk fact…
View article: Prevalence of psychosocial distress in school going adolescents in rural Pakistan: findings from a cross-sectional epidemiological survey
Prevalence of psychosocial distress in school going adolescents in rural Pakistan: findings from a cross-sectional epidemiological survey Open
Aims Early interventions are recommended in adolescents to prevent long-term psychiatric morbidity. However, in Low and Middle Income Countries (LMICs), where there are no child and adolescent mental health services, early identification o…
View article: Effectiveness of a technology-assisted, family volunteers delivered, brief, multicomponent parents’ skills training intervention for children with developmental disorders in rural Pakistan: a cluster randomized controlled trial
Effectiveness of a technology-assisted, family volunteers delivered, brief, multicomponent parents’ skills training intervention for children with developmental disorders in rural Pakistan: a cluster randomized controlled trial Open
Background Globally, there is a large documented gap between needs of families and children with developmental disorders and available services. We adapted the World Health Organization’s mental health Gap-Intervention Guidelines (mhGAP-IG…
View article: Annual Research Review: Achieving universal health coverage for young children with autism spectrum disorder in low‐ and middle‐income countries: a review of reviews
Annual Research Review: Achieving universal health coverage for young children with autism spectrum disorder in low‐ and middle‐income countries: a review of reviews Open
Background Autism presents with similar prevalence and core impairments in diverse populations. We conducted a scoping review of reviews to determine key barriers and innovative strategies which can contribute to attaining universal health…
View article: Impact of Vortioxetine on severity, cognitive dysfunctions, and functionality in patients with major depression: a real world experience from Pakistan
Impact of Vortioxetine on severity, cognitive dysfunctions, and functionality in patients with major depression: a real world experience from Pakistan Open
PREVIDA stands for Pakistani study on Real world Evidence with Vortioxetine in major Depression in Asia. Anywhere in the world, a clinician’s and a patient’s real-world experience with antidepressant treatment is expected to take place min…
View article: Debate: Child and adolescent mental health services in Pakistan; Do we need in‐patient mental health facilities for children and young people?
Debate: Child and adolescent mental health services in Pakistan; Do we need in‐patient mental health facilities for children and young people? Open
Depression and anxiety are leading causes of morbidity in children and adolescents worldwide. In Pakistan, young people are exposed to many chronic adversities including violence, social and economic inequalities, and are at greater risk o…