Sylvain Schnée
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View article: Miniaturized high-throughput conversion of fungal strain collections into chemically characterized extract libraries for antimicrobial discovery
Miniaturized high-throughput conversion of fungal strain collections into chemically characterized extract libraries for antimicrobial discovery Open
Natural products remain vital to drug discovery, with fungi representing an underexplored source of bioactive compounds. Despite advances in LC-MS-based metabolomics that facilitate dereplication and chemical profiling of natural extracts,…
View article: <i>Rpv2</i> is part of a cluster of NLRs specific to <i>Vitis rotundifolia</i> and confers extreme resistance to grapevine downy mildew
<i>Rpv2</i> is part of a cluster of NLRs specific to <i>Vitis rotundifolia</i> and confers extreme resistance to grapevine downy mildew Open
Downy mildew caused by the oomycete Plasmopara viticola is one of the most important diseases affecting grapevine. Resistant varieties are an environmentally-friendly tool to control grapevine downy mildew. Efficient breeding for durable r…
View article: Potato Late Blight Control with a Botanical Product and Reduced Copper Applications
Potato Late Blight Control with a Botanical Product and Reduced Copper Applications Open
Potato late blight (PLB), caused by the pathogenic oomycete Phytophthora infestans, can cause extensive economic damage. Copper is used to combat PLB mainly in organic production. However, its reduction or elimination as a fungicide is a p…
View article: Phyllosphere microbiome-based biocontrol solution against the filamentous pathogens <i>Botrytis cinerea</i> and <i>Plasmopara viticola</i> in grapevine
Phyllosphere microbiome-based biocontrol solution against the filamentous pathogens <i>Botrytis cinerea</i> and <i>Plasmopara viticola</i> in grapevine Open
Plants harbor different microbial communities in their different organs. This difference is due to the various conditions to which the different parts of the plant are subjected. As a result, the phyllosphere microbiome may be drastically …
View article: Potato Late Blight Control with a Botanical Product and Reduced Copper Applications
Potato Late Blight Control with a Botanical Product and Reduced Copper Applications Open
Potato late blight (PLB), due to the pathogenic oomycete, Phytophthora infestans , can cause extensive economic damage, particularly in organic potato production. Although copper is used to combat PLB in organic production, it is banned in…
View article: Occurrence of <i>Aspergillus fumigatus</i> azole resistance in soils from Switzerland
Occurrence of <i>Aspergillus fumigatus</i> azole resistance in soils from Switzerland Open
Aspergillus fumigatus is a fungal species causing diverse diseases in humans. The use of azoles for treatments of A. fumigatus diseases has resulted in azole resistance. Azoles are also widely used in the environment for crop protection, w…
View article: New viruses of Cladosporium sp. expand considerably the taxonomic structure of Gammapartitivirus genus
New viruses of Cladosporium sp. expand considerably the taxonomic structure of Gammapartitivirus genus Open
Despite the fact that Cladosporium sp. are ubiquitous fungi, their viromes have been little studied. By analysing a collection of Cladosporium fungi, two new partitiviruses named Cladosporium cladosporioides partitivirus 1 (CcPV1) and Clad…
View article: New viruses of<i>Cladosporium</i>sp. expand considerably the taxonomic structure of<i>Gammapartitivirus</i>genus
New viruses of<i>Cladosporium</i>sp. expand considerably the taxonomic structure of<i>Gammapartitivirus</i>genus Open
Despite the fact that Cladosporium sp. are ubiquitous fungi, their viromes have been little studied. By analysing a collection of Cladosporium fungi, two new partitiviruses named Cladosporium cladosporioides partitivirus 1 (CcPV1) and Clad…
View article: Digital Holography and artificial intelligence for real-time detection and identification of pathogenic airborne spores
Digital Holography and artificial intelligence for real-time detection and identification of pathogenic airborne spores Open
Ever-growing concerns and governmental restrictions related to the use of pesticides in modern agriculture has driven the need for more adept decision-making tools to minimize unnecessary treatments whilst still efficiently preventing a sp…
View article: Physicochemical Space of Synthetic and Natural Pesticides – A Meta-Analysis
Physicochemical Space of Synthetic and Natural Pesticides – A Meta-Analysis Open
The first commercial use of synthetic pesticides for crop protection dates back to the 1940s, followed by a fast spread of their use and the development of a large number of compounds. In contrast to synthetic pesticides that are now desig…
View article: Chiral Separation of Stilbene Dimers Generated by Biotransformation for Absolute Configuration Determination and Antibacterial Evaluation
Chiral Separation of Stilbene Dimers Generated by Biotransformation for Absolute Configuration Determination and Antibacterial Evaluation Open
A series of complex stilbene dimers have been generated through biotransformation of resveratrol, pterostilbene, and the mixture of both using the enzymatic secretome of Botrytis cinerea Pers. The process starts with achiral molecules and …
View article: Development of downy mildew in grape bunches of susceptible and resistant cultivars: infection pathways and limited systemic spread
Development of downy mildew in grape bunches of susceptible and resistant cultivars: infection pathways and limited systemic spread Open
Background and Aims Plasmopara viticola development in bunches of two grapevine cultivars, the resistant Divico and the susceptible Chasselas, was studied by using microscopy and molecular detection to investigate tissue susceptibility and…
View article: Chemoenzymatic Synthesis of Original Stilbene Dimers Possessing Wnt Inhibition Activity in Triple-Negative Breast Cancer Cells Using the Enzymatic Secretome of Botrytis cinerea Pers.
Chemoenzymatic Synthesis of Original Stilbene Dimers Possessing Wnt Inhibition Activity in Triple-Negative Breast Cancer Cells Using the Enzymatic Secretome of Botrytis cinerea Pers. Open
The Wnt signaling pathway controls multiple events during embryonic development of multicellular animals and is carcinogenic when aberrantly activated in adults. Breast cancer and triple-negative breast cancer (TNBC) in particular depend u…
View article: Chemoenzymatic Synthesis of Complex Phenylpropanoid Derivatives by the Botrytis cinerea Secretome and Evaluation of Their Wnt Inhibition Activity
Chemoenzymatic Synthesis of Complex Phenylpropanoid Derivatives by the Botrytis cinerea Secretome and Evaluation of Their Wnt Inhibition Activity Open
In this study, a series of complex phenylpropanoid derivatives were obtained by chemoenzymatic biotransformation of ferulic acid, caffeic acid, and a mixture of both acids using the enzymatic secretome of Botrytis cinerea. These substrates…
View article: Influence of abiotic factors, inoculum source, and cultivar susceptibility on the potato tuber blemish diseases black dot ( <i>Colletotrichum coccodes</i> ) and silver scurf ( <i>Helminthosporium solani</i> )
Influence of abiotic factors, inoculum source, and cultivar susceptibility on the potato tuber blemish diseases black dot ( <i>Colletotrichum coccodes</i> ) and silver scurf ( <i>Helminthosporium solani</i> ) Open
Black dot and silver scurf are potato blemish diseases whose economic impact has increased in recent years. Because their symptomatology on tubers is visually similar, disease assessment does not usually differentiate between the two patho…
View article: Isothiocyanate Derivatives of Glucosinolates as Efficient Natural Fungicides
Isothiocyanate Derivatives of Glucosinolates as Efficient Natural Fungicides Open
Fungal pathogens on crops account for losses that exceed US$200 billion annually. At present, chemical fungicides are widely used in the agricultural industry. Many of these products have a detrimental effect on human and animal health and…
View article: Insights on the Structural and Metabolic Resistance of Potato (Solanum tuberosum) Cultivars to Tuber Black Dot (Colletotrichum coccodes)
Insights on the Structural and Metabolic Resistance of Potato (Solanum tuberosum) Cultivars to Tuber Black Dot (Colletotrichum coccodes) Open
Black dot is a blemish disease of potato tubers caused by the phytopathogenic fungus Colletotrichum coccodes. Qualitative resistance (monogenic) that leads to the hypersensitive response has not been reported against black dot, but commerc…
View article: The unbearable lightness of sequenced-based identification
The unbearable lightness of sequenced-based identification Open
International audience
View article: Pathogenicity Traits Correlate With the Susceptible Vitis vinifera Leaf Physiology Transition in the Biotroph Fungus Erysiphe necator: An Adaptation to Plant Ontogenic Resistance
Pathogenicity Traits Correlate With the Susceptible Vitis vinifera Leaf Physiology Transition in the Biotroph Fungus Erysiphe necator: An Adaptation to Plant Ontogenic Resistance Open
How and when the pathogen cycle is disrupted during plant development is crucial for harnessing ontogenic resistance in sustainable agriculture. Ontogenic resistance against powdery mildew (Erysiphe necator) was quantified on Vitis vinifer…
View article: Polyphenolic profile and stilbene content of Albanian “Kallmet” monovarietal wine
Polyphenolic profile and stilbene content of Albanian “Kallmet” monovarietal wine Open
Aim: The aim of this work was to characterize the phenolic content of wines from the most promising autochthonous red grape variety in Albania, the Kallmet.Methods and results: To make this first survey, 16 commercial monovarietal Kallmet …