Sylvia M. Gustin
YOU?
Author Swipe
View article: Cervical atrophy following complete thoracic spinal cord injury: Insights from a multinational cohort
Cervical atrophy following complete thoracic spinal cord injury: Insights from a multinational cohort Open
Background Spinal cord injury (SCI) results in neurodegeneration both at and above the lesion site. While cervical cord atrophy is well characterized in populations of mixed cervical, thoracic and/or lumbar injuries, the remote morphologic…
View article: The cortical mechanisms underlying the analgesic effects of repetitive transcranial magnetic stimulation: protocol for a systematic review and meta-analysis
The cortical mechanisms underlying the analgesic effects of repetitive transcranial magnetic stimulation: protocol for a systematic review and meta-analysis Open
International Prospective Register of Systematic Reviews CRD42024594054.
View article: Chronic pain and differential brain morphology alterations of childhood maltreatment, trauma exposure in adulthood and their cumulative effects in the UK Biobank
Chronic pain and differential brain morphology alterations of childhood maltreatment, trauma exposure in adulthood and their cumulative effects in the UK Biobank Open
Background Chronic pain is associated with heightened prevalence of trauma exposure. Separate studies of chronic pain and trauma report overlapping brain alterations in older adults (age over 60). Despite this close relationship, the inter…
View article: “It’s just crucial to deal with emotions as well as the pain” A qualitative acceptability study of an online emotion regulation skills-focused intervention for people with chronic pain
“It’s just crucial to deal with emotions as well as the pain” A qualitative acceptability study of an online emotion regulation skills-focused intervention for people with chronic pain Open
Findings highlight the need for clinical assessment to gauge client readiness for an emotionally focused approach, assess sensitivity to others' emotions in a group setting, and ensure personalisation of digital components to enhance engag…
View article: Alexithymia moderates brain function during suppression of negative emotions in fibromyalgia
Alexithymia moderates brain function during suppression of negative emotions in fibromyalgia Open
Fibromyalgia is associated with altered brain function and emotion regulation difficulties. Alexithymia is common in fibromyalgia and may further affect emotion regulation in this population. This study examined the interplay of alexithymi…
View article: Convergent structural brain alterations in chronic pain: A multi-metric individual participant data meta-analysis
Convergent structural brain alterations in chronic pain: A multi-metric individual participant data meta-analysis Open
Meta-analyses are a valuable tool in evidence-based research and have contributed to our understanding of structural brain changes in chronic pain. Meta-analyses are also limited by published summary statistics and quality/completeness of …
View article: Ketamine and other NMDA receptor antagonists for chronic pain
Ketamine and other NMDA receptor antagonists for chronic pain Open
Protocol available: doi.org/10.1002/14651858.CD015373.
View article: Cumulative impacts of early life adversity and persistent/recurrent pain in children: A longitudinal normative modelling study from the ABCD Study cohort
Cumulative impacts of early life adversity and persistent/recurrent pain in children: A longitudinal normative modelling study from the ABCD Study cohort Open
Background. Compared to typically developing children, those experiencing persistent/recurrent pain (PRP) often report increased exposure to early life adversity (ELA). Separate studies of children experiencing PRP or exposed to ELA show s…
View article: Stress‐Related Brain Alterations in Chronic Pain
Stress‐Related Brain Alterations in Chronic Pain Open
Background Stress symptoms are commonly experienced by people with chronic pain. Although stress and chronic pain are associated with similar effects on brain morphology, the present study aims to clarify the relationship between stress se…
View article: Online Dialectical Behavioral Therapy for Emotion Dysregulation in People With Chronic Pain
Online Dialectical Behavioral Therapy for Emotion Dysregulation in People With Chronic Pain Open
Importance Current therapeutic approaches are inaccessible to many people with chronic pain and frequently fail to address emotion dysregulation as a key factor in psychological comorbidity and pain intensity. An effective and accessible e…
View article: The cortical mechanisms underlying the analgesic effects of repetitive transcranial magnetic stimulation: Protocol for a Systematic Review and Meta-analysis
The cortical mechanisms underlying the analgesic effects of repetitive transcranial magnetic stimulation: Protocol for a Systematic Review and Meta-analysis Open
Introduction: Repetitive transcranial magnetic stimulation (rTMS) is a promising, safe, and non-invasive treatment for pain. However, there is no clear understanding of the cortical mechanisms underlying the analgesic effect of rTMS. One t…
View article: Cerebellar tissue properties alterations in fibromyalgia: a T1w/T2w ratio study
Cerebellar tissue properties alterations in fibromyalgia: a T1w/T2w ratio study Open
Fibromyalgia is associated with elevated levels of comorbid anxiety and depression, together impacting brain morphology possibly reflecting common underlying biological processes. The present study aims to determine the difference in regio…
View article: Why might fears and worries persist after a pain education–grounded multimodal intervention for chronic back pain? A qualitative study
Why might fears and worries persist after a pain education–grounded multimodal intervention for chronic back pain? A qualitative study Open
Introduction: The effect of pain education (PE) on pain intensity and function diminishes after a few months in people with chronic low back pain (CLBP). One possible explanation is the return of underlying fears and worries related to the…
View article: A home-based self-directed EEG neurofeedback intervention for people with chronic neuropathic pain following spinal cord injury (the StoPain Trial): description of the intervention
A home-based self-directed EEG neurofeedback intervention for people with chronic neuropathic pain following spinal cord injury (the StoPain Trial): description of the intervention Open
View article: ENIGMA-Chronic Pain: a worldwide initiative to identify brain correlates of chronic pain
ENIGMA-Chronic Pain: a worldwide initiative to identify brain correlates of chronic pain Open
International audience
View article: Posttraumatic stress symptoms in chronic pain: impacts on brain morphology
Posttraumatic stress symptoms in chronic pain: impacts on brain morphology Open
Background. Posttraumatic stress symptoms (PTSS) are commonly experienced by people with chronic pain. Although PTSS and chronic pain are associated with similar effects on brain morphology, the present study aimed to clarify the relations…
View article: Emotion regulation skills‐focused interventions for chronic pain: A systematic review and meta‐analysis
Emotion regulation skills‐focused interventions for chronic pain: A systematic review and meta‐analysis Open
Objectives To investigate the effect of emotion regulation skills‐focused (ERSF) interventions to reduce pain intensity and improve psychological outcomes for people with chronic pain and to narratively report on safety and intervention co…
View article: Central neuropathic pain
Central neuropathic pain Open
View article: Heart Rate Variability Biofeedback in Adults with a Spinal Cord Injury: A Laboratory Framework and Case Series
Heart Rate Variability Biofeedback in Adults with a Spinal Cord Injury: A Laboratory Framework and Case Series Open
Heart rate variability biofeedback (HRV-F) is a neurocardiac self-regulation therapy that aims to regulate cardiac autonomic nervous system activity and improve cardiac balance. Despite benefits in various clinical populations, no study ha…
View article: Cortical Mechanisms Underlying Immersive Interactive Virtual Walking Treatment for Amelioration of Neuropathic Pain after Spinal Cord Injury: Findings from a Preliminary Investigation of Thalamic Inhibitory Function
Cortical Mechanisms Underlying Immersive Interactive Virtual Walking Treatment for Amelioration of Neuropathic Pain after Spinal Cord Injury: Findings from a Preliminary Investigation of Thalamic Inhibitory Function Open
Background: Neuropathic pain following spinal cord injury (SCI) affects approximately 60% of individuals with SCI. Effective pharmacological and non-pharmacological treatments remain elusive. We recently demonstrated that our immersive vir…
View article: Self-supervised cross-modal visual retrieval from brain activities
Self-supervised cross-modal visual retrieval from brain activities Open
We study the problem of restoring visual stimuli from electroencephalography (EEG) signals. Using a supervised classification-then-generation framework, the reconstruction-based approaches learn the mapping between distributions of two mod…
View article: Internet-Delivered Dialectical Behavioral Therapy Skills Training for Chronic Pain: Protocol for a Randomized Controlled Trial
Internet-Delivered Dialectical Behavioral Therapy Skills Training for Chronic Pain: Protocol for a Randomized Controlled Trial Open
Background Emotion dysregulation is key to the development and maintenance of chronic pain, feeding into a cycle of worsening pain and disability. Dialectical behavioral therapy (DBT), an evidence-based treatment for complex transdiagnosti…
View article: Depressive symptoms moderate functional connectivity within the emotional brain in chronic pain
Depressive symptoms moderate functional connectivity within the emotional brain in chronic pain Open
Background Depressive symptoms are often comorbid with chronic pain. These conditions share aberrant emotion processing and regulation, as well as having common brain networks. However, the relationship between depressive symptoms and chro…
View article: Comparative effectiveness and safety of analgesic medicines for adults with acute non-specific low back pain: systematic review and network meta-analysis
Comparative effectiveness and safety of analgesic medicines for adults with acute non-specific low back pain: systematic review and network meta-analysis Open
Objective To evaluate the comparative effectiveness and safety of analgesic medicines for acute non-specific low back pain. Design Systematic review and network meta-analysis. Data sources Medline, PubMed, Embase, CINAHL, CENTRAL, Clinical…
View article: Ketamine and other NMDA receptor antagonists for chronic pain
Ketamine and other NMDA receptor antagonists for chronic pain Open
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To evaluate the benefits and harms of ketamine and other NDMA receptor antagonists compared to placebo, usual care, or other medicines for adults with …
View article: “My Back is Fit for Movement”: A Qualitative Study Alongside a Randomized Controlled Trial for Chronic Low Back Pain
“My Back is Fit for Movement”: A Qualitative Study Alongside a Randomized Controlled Trial for Chronic Low Back Pain Open
View article: Evaluation of emotion-centric psychological interventions for chronic pain: protocol for a systematic review and meta-analysis
Evaluation of emotion-centric psychological interventions for chronic pain: protocol for a systematic review and meta-analysis Open
Introduction Chronic pain, defined as pain persisting longer than 3 months, is more than an unpleasant sensory experience. Persistent negative emotions and emotional comorbidities, such as depression and anxiety, plague people with chronic…
View article: Internet-Delivered Dialectical Behavioral Therapy Skills Training for Chronic Pain: Protocol for a Randomized Controlled Trial (Preprint)
Internet-Delivered Dialectical Behavioral Therapy Skills Training for Chronic Pain: Protocol for a Randomized Controlled Trial (Preprint) Open
BACKGROUND Emotion dysregulation is key to the development and maintenance of chronic pain, feeding into a cycle of worsening pain and disability. Dialectical behavioral therapy (DBT), an evidence-based treatment for complex transdiagnost…
View article: Corrigendum: Reduced Glutamate in the Medial Prefrontal Cortex Is Associated With Emotional and Cognitive Dysregulation in People With Chronic Pain
Corrigendum: Reduced Glutamate in the Medial Prefrontal Cortex Is Associated With Emotional and Cognitive Dysregulation in People With Chronic Pain Open
[This corrects the article DOI: 10.3389/fneur.2019.01110.].
View article: Trans-Spinal Electrical Stimulation Therapy for Functional Rehabilitation after Spinal Cord Injury: Review
Trans-Spinal Electrical Stimulation Therapy for Functional Rehabilitation after Spinal Cord Injury: Review Open
Spinal cord injury (SCI) is one of the most debilitating injuries in the world. Complications after SCI, such as respiratory issues, bowel/bladder incontinency, pressure ulcers, autonomic dysreflexia, spasticity, pain, etc., lead to immens…