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View article: Satisfaction in surgically treated patients with degenerative cervical myelopathy: an observational study from the Canadian Spine Outcomes and Research Network
Satisfaction in surgically treated patients with degenerative cervical myelopathy: an observational study from the Canadian Spine Outcomes and Research Network Open
Improvement in Patient Reported Outcomes and MJOA are strongly associated with patient satisfaction after surgery for DCM. The only baseline PRO associated with 12-months satisfaction was SF-12-MCS. No modifiable patient baseline character…
Spinal Cord Injuries Secondary to Mountain Biking Accidents — A Cause for National Alarm Open
While much attention in North America has been placed on hockey and other high impact sports as causes of spinal cord injury (SCI), over the past two decades, our Level 1 trauma center has experienced a much higher number of SCI from off-r…
Pattern of neurological recovery in persons with an acute cervical spinal cord injury over the first 14 days post injury Open
Introduction Following a traumatic spinal cord injury (SCI) it is critical to document the level and severity of injury. Neurological recovery occurs dynamically after injury and a baseline neurological exam offers a snapshot of the patien…
View article: Effectiveness of prophylactic intranasal photodynamic disinfection therapy and chlorhexidine gluconate body wipes for surgical site infection prophylaxis in adult spine surgery
Effectiveness of prophylactic intranasal photodynamic disinfection therapy and chlorhexidine gluconate body wipes for surgical site infection prophylaxis in adult spine surgery Open
Preoperative nPDT-CHG administration is an effective prophylactic strategy for spinal SSIs, with significant cost savings. Given its rapid action, minimal risk of antimicrobial resistance, broad-spectrum activity and high compliance rate, …
Impact of Specialized Versus Non-Specialized Acute Hospital Care on Survival Among Patients With Acute Incomplete Traumatic Spinal Cord Injuries: A Population-Based Observational Study from British Columbia, Canada Open
Given the complexity of care necessitated after an acute traumatic spinal cord injury (SCI), it seems intuitively beneficial for such care to be delivered at hospitals with specialized SCI expertise. Demonstrating these benefits is not str…
F.5 Spinal column and spinal cord injuries secondary to mountain biking accidents: a 15-year review at a provincial spine referral centre Open
Background: Mountain biking (MTB) is an increasingly popular sport that has been associated with serious spinal injuries, which can have devastating effects on patients and significant impacts on healthcare resources. Herein, we characteri…
Degenerative spinal conditions requiring emergency surgery: an evolving crisis in a publicly funded health care system Open
We observed worse perioperative outcomes for patients requiring emergency surgery for degenerative spinal conditions than for patients who were scheduled for surgery. Patients who decompensated while on the surgical waitlist had the worst …
The Role of Frailty and Sarcopenia in Predicting Major Adverse Events, Length of Stay and Reoperation Following <i>En Bloc</i> Resection of Primary Tumours of the Spine Open
Study Design Retrospective observational cohort study. Objective En bloc resection for primary tumours of the spine is associated with a high rate of adverse events (AEs). The objective was to explore the relationship between frailty/sarco…
View article: Association of CSF and Serum Neurofilament Light and Glial Fibrillary Acidic Protein, Injury Severity, and Outcome in Spinal Cord Injury
Association of CSF and Serum Neurofilament Light and Glial Fibrillary Acidic Protein, Injury Severity, and Outcome in Spinal Cord Injury Open
Registered on ClinicalTrials.gov: NCT00135278 (March 2006) and NCT01279811 (January 2012).
View article: Dysfunctional paraspinal muscles in adult spinal deformity patients lead to increased spinal loading
Dysfunctional paraspinal muscles in adult spinal deformity patients lead to increased spinal loading Open
The histopathological observations suggest diverse mechanisms of potential functional impairment. The large variations observed in muscle biomechanical properties can have a dramatic influence on spinal forces. These early findings highlig…
P.225 Factors Contributing to Prolonged Length of Stay in Adults Undergoing Spine Surgery: Results from a Quaternary Spinal Care Center Open
Background: Prolonged length of stay (LOS) is associated with increased resource utilization and worse outcomes. The goal of this study is identifying patient, surgical and systemic factors associated with prolonged LOS overall and per dia…
P.227 Investigating the changes in ITP after CSF drainage in patients with acute traumatic SCI: Results from a Quaternary Spinal Care Center Open
Background: Mean arterial pressure augmentation is one current established practice for management of patients with SCI. We present the first data investigating the effectiveness of Intrathecal Pressure (ITP) reduction through CSF drainage…
Patient-Reported Outcomes Following Surgery for Lumbar Disc Herniation: Comparison of a Universal and Multitier Health Care System Open
Study Design Ambispective cohort study. Objective Canada has a government-funded universal health care system. The United States utilizes a multitier public and private system. The objective is to investigate differences in clinical outcom…
Development of a machine learning algorithm for predicting in-hospital and 1-year mortality after traumatic spinal cord injury Open
The SCIRS can predict in-hospital and 1-year mortality following tSCI more accurately than the ISS. The SCIRS can be used in research to reduce bias in estimating parameters and can help adjust for coefficients during model development. Fu…
View article: Proteomic portraits reveal evolutionarily conserved and divergent responses to spinal cord injury
Proteomic portraits reveal evolutionarily conserved and divergent responses to spinal cord injury Open
Despite the emergence of promising therapeutic approaches in preclinical studies, the failure of large-scale clinical trials leaves clinicians without effective treatments for acute spinal cord injury (SCI). These trials are hindered by th…
View article: Proteomic Portraits Reveal Evolutionarily Conserved and Divergent Responses to Spinal Cord Injury
Proteomic Portraits Reveal Evolutionarily Conserved and Divergent Responses to Spinal Cord Injury Open
Despite the emergence of promising therapeutic approaches in preclinical studies, the failure of large-scale clinical trials leaves clinicians without effective treatments for acute spinal cord injury (SCI). These trials are hindered by th…
Effect of Frailty on Outcome after Traumatic Spinal Cord Injury Open
Frailty negatively affects outcome in elective spine surgery populations. This study sought to determine the effect of frailty on patient outcome after traumatic spinal cord injury (tSCI). Patients with tSCI were identified from our prospe…
Clinical outcomes research in spine surgery: what are appropriate follow-up times? Open
OBJECTIVE There has been a generic dictum in spine and musculoskeletal clinical research that a minimum 2-year follow-up is necessary for patient-reported outcomes (PROs) to adequately assess the therapeutic effect of surgery; however, the…
An assessment of frailty as a tool for risk stratification in adult spinal deformity surgery Open
OBJECTIVE The goal of this study was to analyze the value of an adult spinal deformity frailty index (ASD-FI) in preoperative risk stratification. Preoperative risk assessment is imperative before procedures known to have high complication…
The role of revision surgery and adjuvant therapy following subtotal resection of osteosarcoma of the spine: a systematic review with meta-analysis Open
OBJECTIVE Primary osteosarcoma of the spine is a rare osseous neoplasm. While previously reported retrospective studies have demonstrated that overall patient survival is impacted mostly by en bloc resection and chemotherapy, the continued…