Tommy Nyberg
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Doubly robust integration of nonprobability and probability survey data Open
Doubly robust estimators combine an inverse probability weighting estimator and a mass imputation estimator. Several doubly robust estimators for estimating the population mean (or prevalence) of an outcome have been proposed for integrati…
View article: A standardised protocol for relative SARS-CoV-2 variant severity assessment, applied to Omicron BA.1 and Delta in six European countries, October 2021 to February 2022
A standardised protocol for relative SARS-CoV-2 variant severity assessment, applied to Omicron BA.1 and Delta in six European countries, October 2021 to February 2022 Open
Several SARS-CoV-2 variants that evolved during the COVID-19 pandemic have appeared to differ in severity, based on analyses of single-country datasets. With decreased testing and sequencing, international collaborative studies will become…
Directions of change in intrinsic case severity across successive SARS-CoV-2 variant waves have been inconsistent Open
The direction of change in intrinsic severity between successively emerging SARS-CoV-2 variants was inconsistent, reminding us that the intrinsic severity of future SARS-CoV-2 variants remains uncertain.
View article: A standardised protocol for assessment of relative SARS-CoV-2 variant severity, with application to severity risk for COVID-19 cases infected with Omicron BA.1 compared to Delta variants in six European countries
A standardised protocol for assessment of relative SARS-CoV-2 variant severity, with application to severity risk for COVID-19 cases infected with Omicron BA.1 compared to Delta variants in six European countries Open
Several SARS-CoV-2 variants that evolved during the COVID-19 pandemic have appeared to differ in severity, based on analyses of single-country datasets. With decreased SARS-CoV-2 testing and sequencing, international collaborative studies …
View article: CanRisk-Prostate: A Comprehensive, Externally Validated Risk Model for the Prediction of Future Prostate Cancer
CanRisk-Prostate: A Comprehensive, Externally Validated Risk Model for the Prediction of Future Prostate Cancer Open
PURPOSE Prostate cancer (PCa) is highly heritable. No validated PCa risk model currently exists. We therefore sought to develop a genetic risk model that can provide personalized predicted PCa risks on the basis of known moderate- to high-…
View article: Adjusting for time of infection or positive test when estimating the risk of a post-infection outcome in an epidemic
Adjusting for time of infection or positive test when estimating the risk of a post-infection outcome in an epidemic Open
When comparing the risk of a post-infection binary outcome, for example, hospitalisation, for two variants of an infectious pathogen, it is important to adjust for calendar time of infection. Typically, the infection time is unknown and po…
View article: Inconsistent directions of change in case severity across successive SARS-CoV-2 variant waves suggests an unpredictable future
Inconsistent directions of change in case severity across successive SARS-CoV-2 variant waves suggests an unpredictable future Open
Objective To determine how the severity of successively dominant SARS-CoV-2 variants changed over the course of the COVID-19 pandemic. Design Retrospective cohort analysis. Setting Community- and hospital-sequenced COVID-19 cases in the NH…
Hospitalization and Mortality Risk for COVID-19 Cases With SARS-CoV-2 AY.4.2 (VUI-21OCT-01) Compared to Non-AY.4.2 Delta Variant Sublineages Open
To investigate if the AY.4.2 sublineage of the SARS-CoV-2 delta variant is associated with hospitalization and mortality risks that differ from non-AY.4.2 delta risks, we performed a retrospective cohort study of sequencing-confirmed COVID…
View article: Adjusting for time of infection or positive test when estimating the risk of a post-infection outcome in an epidemic
Adjusting for time of infection or positive test when estimating the risk of a post-infection outcome in an epidemic Open
When comparing the risk of a post-infection binary outcome, e.g. hospitalisation, for two variants of an infectious pathogen, it is important to adjust for calendar time of infection to avoid the confounding that would occur if the relativ…
Risk of hospital admission for patients with SARS-CoV-2 variant B.1.1.7: cohort analysis Open
Objective: To evaluate the relation between diagnosis of covid-19 with SARS-CoV-2 variant B.1.1.7 (also known as variant of concern 202012/01) and the risk of hospital admission compared with diagnosis with wild-type SARS-CoV-2 variants. D…
Acute and long-term grief reactions and experiences in parentally cancer-bereaved teenagers Open
Background Previous research shows that many cancer-bereaved youths report unresolved grief several years after the death of a parent. Grief work hypothesis suggests that, in order to heal, the bereaved needs to process the pain of grief i…
Acute and long-term grief reactions and experiences in parentally cancer-bereaved teenagers Open
Background Previous research shows that many cancer-bereaved youths report unresolved grief several years after the death of a parent. Grief work hypothesis suggests that, in order to heal, the bereaved needs to process the pain of grief i…
A Comprehensive Genetic Risk Model for the Prediction of Future Prostate Cancer Open
The only established prostate cancer (PCa) risk factors are age, ethnic ancestry and family history. Several PCa genetic susceptibility variants have been identified, including rare moderate-to-high risk pathogenic variants (PVs) and commo…
Prostate Cancer Risk by BRCA2 Genomic Regions Open
A BRCA2 prostate cancer cluster region (PCCR) was recently proposed (c.7914 to 3') wherein pathogenic variants (PVs) are associated with higher prostate cancer (PCa) risk than PVs elsewhere in the BRCA2 gene. Using a prospective cohort stu…
View article: Prostate Cancer Risks for Male BRCA1 and BRCA2 Mutation Carriers: A Prospective Cohort Study
Prostate Cancer Risks for Male BRCA1 and BRCA2 Mutation Carriers: A Prospective Cohort Study Open
BACKGROUND: BRCA1 and BRCA2 mutations have been associated with prostate cancer (PCa) risk but a wide range of risk estimates have been reported that are based on retrospective studies. OBJECTIVE: To estimate relative and absolute PCa risk…
Losing a parent to cancer as a teenager: Family cohesion in childhood, teenage, and young adulthood as perceived by bereaved and non‐bereaved youths Open
Objective The aim of this study was to investigate levels of perceived family cohesion during childhood, teenage years, and young adulthood in cancer‐bereaved youths compared with non‐bereaved peers. Methods In this nationwide, population‐…
View article: Bladder health in patients treated with BCG instillations for T1G2-G3 bladder cancer – a follow-up five years after the start of treatment
Bladder health in patients treated with BCG instillations for T1G2-G3 bladder cancer – a follow-up five years after the start of treatment Open
Patients with bladder cancer T1G2-G3 had disease-specific symptoms present already before the start of the BCG. The burden of symptoms was reduced over time and showed that the bladder might recover. BCG instillations had side-effects that…
Quality of Life after Radical Prostatectomy or Watchful Waiting with or without Androgen Deprivation Therapy: The Scandinavian Prostate Cancer Group-4 Randomized Trial Open
Background: Men with prostate cancer experience adjuvant androgen deprivation therapy (ADT) differently. Objective: To evaluate ADT effect on quality of life, the experience of clinical check-ups, and differences in cancer information as e…
Accuracy in local staging of prostate cancer by adding a three-dimensional T2-weighted sequence with radial reconstructions in magnetic resonance imaging Open
Background The evidence supporting the use of magnetic resonance imaging (MRI) in prostate cancer detection has been established, but its accuracy in local staging is questioned. Purpose To investigate the additional value of multi-planar …