Fatima Tuz Zahra
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View article: Real-world efficacy outcomes of epcoritamab and glofitamab in Relapsed/Refractory aggressive B-cell lymphoma: A single-center cohort emphasizing trial-ineligible populations
Real-world efficacy outcomes of epcoritamab and glofitamab in Relapsed/Refractory aggressive B-cell lymphoma: A single-center cohort emphasizing trial-ineligible populations Open
Introduction The CD20xCD3 bispecific antibodies (BsAbs), epcoritamab (Epco) and glofitamab (Glofi), have emerged as effective therapies for relapsed/refractory (RR) B-cell non-Hodgkin lymphomas (B-NHL), demonstrating high response rates in…
View article: Clinical features and outcomes of adult T-cell leukemia/lymphoma across world regions: An international retrospective cohort study
Clinical features and outcomes of adult T-cell leukemia/lymphoma across world regions: An international retrospective cohort study Open
Background: Adult T-cell leukemia/lymphoma (ATL) has a dismal prognosis and disproportionately affects regions endemic in Human T-lymphotropic virus-1 (HTLV-1) infection. While treatment approaches vary globally due to differences in drug …
View article: Outcomes of CD20xCD3 bispecific antibody therapy as holding or bridging therapy prior to chimeric antigen receptor T-cell infusion in aggressive B-cell lymphomas
Outcomes of CD20xCD3 bispecific antibody therapy as holding or bridging therapy prior to chimeric antigen receptor T-cell infusion in aggressive B-cell lymphomas Open
Introduction CD19-directed chimeric antigen receptor T-cell (CAR-T) therapy is approved as second-line treatment for aggressive B-cell lymphoma (aBCL), while CD20xCD3 bispecific antibodies (BsAbs) are approved in the third-line setting. Al…
View article: Real-world survival outcomes following allogeneic hematopoietic cell transplantation in peripheral T-cell lymphomas: A Florida multi-institutional cohort study
Real-world survival outcomes following allogeneic hematopoietic cell transplantation in peripheral T-cell lymphomas: A Florida multi-institutional cohort study Open
Introduction: Peripheral T-cell lymphomas (PTCL) are a heterogeneous group of aggressive lymphoid malignancies characterized by high relapse and mortality rates. Allogeneic hematopoietic cell transplantation (allo-HCT) is recommended upfro…
View article: Not so exclusive: Co-mutations in JAK2, MPL and CALR define distinct hematologic and clonal signatures
Not so exclusive: Co-mutations in JAK2, MPL and CALR define distinct hematologic and clonal signatures Open
Background: The canonical driver mutations in JAK2, CALR, and MPL are typically regarded as mutually exclusive in myeloproliferative neoplasms (MPNs). However, co-occurrence is increasingly recognized, raising questions about their clinica…
View article: SURG-06. Treatment Outcomes Of Hydrocephalus Management Strategies In Patients With Cerebellopontine Angle Lesions
SURG-06. Treatment Outcomes Of Hydrocephalus Management Strategies In Patients With Cerebellopontine Angle Lesions Open
INTRODUCTION Approximately 3.7–42% of cerebellopontine angle (CPA) lesions may present with symptomatic or asymptomatic Hydrocephalus (HCP), often due to cerebrospinal fluid blockage at the fourth ventricle. The optimal management strategy…
View article: SUN-266 Neuroendocrine Carcinoma: Survival Analysis and Mortality-to-incidence (MIR) ratio from SEER Database
SUN-266 Neuroendocrine Carcinoma: Survival Analysis and Mortality-to-incidence (MIR) ratio from SEER Database Open
Disclosure: S. Bajwa: None. H. Ali: None. U. Bajwa: None. A. Imran: None. F. Mohsin: None. F. Tuz Zahra: None. J. Santhi: None. R. Thirumaran: None. Background:Neuroendocrine Carcinomas (NC) are rare, high grade poorly differentiated tumor…
View article: Emotional Dysregulation and Autonomic Dysfunction in Takotsubo Cardiomyopathy Patients
Emotional Dysregulation and Autonomic Dysfunction in Takotsubo Cardiomyopathy Patients Open
Emotional dysregulation is strongly associated with autonomic dysfunction in TCM patients, even after adjusting for anxiety, depression, and clinical variables. These findings underscore the importance of integrating psychological assessme…
View article: ARTIFICIAL INTELLIGENCE IN EARLY DETECTION OF TEMPOROMANDIBULAR JOINT DISORDERS-A SYSTEMATIC REVIEW
ARTIFICIAL INTELLIGENCE IN EARLY DETECTION OF TEMPOROMANDIBULAR JOINT DISORDERS-A SYSTEMATIC REVIEW Open
Background: Temporomandibular joint disorders (TMDs) affect a significant portion of the population and are a leading cause of chronic orofacial pain and functional limitation. Early diagnosis is crucial for effective intervention, yet con…
View article: Assessment of diagnostic accuracy of Ziehl-Neelsen microscopy and GeneXpert MTB/ RIF assays from pulmonary and extra pulmonary specimens in a tertiary care hospital setting.
Assessment of diagnostic accuracy of Ziehl-Neelsen microscopy and GeneXpert MTB/ RIF assays from pulmonary and extra pulmonary specimens in a tertiary care hospital setting. Open
Objective: To compare the diagnostic accuracy of GeneXpert over ZN microscopy in pulmonary and extra pulmonary suspected tuberculosis samples. Study Design: Retrospective Cross-sectional study. Setting: Tertiary Care Hospital, Rawalpindi. …
View article: Study of Feto-Maternal Outcome in Premature Rupture of Membranes at Term Pregnancy in a Tertiary Care Institute
Study of Feto-Maternal Outcome in Premature Rupture of Membranes at Term Pregnancy in a Tertiary Care Institute Open
Background: The Term “Preterm Rupture of Membranes” (PROM) complicates approximately 8-10% of all pregnancies and is associated with increased maternal as well as neonatal morbidity. This study aimed to assess Feto-maternal outcomes follow…
View article: EVALUATING THE ROLE OF IMMATURE PLATELET FRACTION IN PLATELET ENGRAFTMENT IN HEMATOPOIETIC STEM CELL TRANSPLANTATION
EVALUATING THE ROLE OF IMMATURE PLATELET FRACTION IN PLATELET ENGRAFTMENT IN HEMATOPOIETIC STEM CELL TRANSPLANTATION Open
Background: Hematopoietic stem cell transplantation (HSCT) is a bone marrow condition in which platelet engraftment is a vital indicator of the condition. The immature platelet fraction (IPF) refers to the percentage composition of the rec…
View article: ARTIFICIAL INTELLIGENCE IN AUTOMATED INTERPRETATION OF DENTAL RADIOGRAPHS: A SYSTEMATIC REVIEW
ARTIFICIAL INTELLIGENCE IN AUTOMATED INTERPRETATION OF DENTAL RADIOGRAPHS: A SYSTEMATIC REVIEW Open
Background: Artificial intelligence (AI) is increasingly being integrated into dental diagnostics, particularly in the interpretation of radiographic images. Despite promising developments, current evidence on the diagnostic performance, e…
View article: Applying the Discovery Learning Approach to Enhance Students' Reading Skills at State Islamic Senior High School 1 West Aceh (An Experimental Study)
Applying the Discovery Learning Approach to Enhance Students' Reading Skills at State Islamic Senior High School 1 West Aceh (An Experimental Study) Open
This study investigates the application of the discovery learning method to enhance students’ reading skills at State Islamic Senior High School 1, Western Aceh. The research was prompted by classroom observations indicating that Arabic la…
View article: Association Between Diabetic Peripheral Neuropathy and Risk of Falls in Adults with Type 2 Diabetes: A Narrative Review
Association Between Diabetic Peripheral Neuropathy and Risk of Falls in Adults with Type 2 Diabetes: A Narrative Review Open
Background: Diabetic peripheral neuropathy (DPN) is a prevalent and debilitating complication of type 2 diabetes mellitus (T2DM), characterized by progressive sensory and motor deficits. These impairments significantly increase the risk of…
View article: EXPLORING TRANSLATION DYNAMICS: SEMANTIC ANALYSIS OF MOHSIN HAMID’S THE LAST WHITE MAN
EXPLORING TRANSLATION DYNAMICS: SEMANTIC ANALYSIS OF MOHSIN HAMID’S THE LAST WHITE MAN Open
Current research is based on the application of Peter Newmark’s translation theory on Mohsin Hamid’s novel The Last White Man. The study seeks to examine the linguistic strategies employed in the translated text and the extent to which sem…
View article: Addressing the Needs of Breast Cancer Survivors
Addressing the Needs of Breast Cancer Survivors Open
Introduction Breast cancer survivors experience unique treatment-related side effects that have long-standing and life-altering implications. These remain a challenging aspect both in terms of diagnosis and management for these patients. O…
View article: COMPARISON OF WOUND INFECTION AFTER PILONIDAL SINUS EXCISION WITH PRIMARY REPAIR VERSUS FLAP COVERAGE: A RANDOMIZED CONTROLLED TRIAL
COMPARISON OF WOUND INFECTION AFTER PILONIDAL SINUS EXCISION WITH PRIMARY REPAIR VERSUS FLAP COVERAGE: A RANDOMIZED CONTROLLED TRIAL Open
Background: Pilonidal sinus disease (PSD) is a chronic inflammatory condition affecting the sacrococcygeal region, often seen in young adults. Its management poses a surgical dilemma due to varied treatment options and recurrence risks. Pr…
View article: Foundational concepts of circular intuitionistic fuzzy soft sets applied to sustainable decision-making for cement plant site selection
Foundational concepts of circular intuitionistic fuzzy soft sets applied to sustainable decision-making for cement plant site selection Open
The optimal selection of a site for cement plant development is a multifaceted decision-making process that demands careful consideration of environmental, economic, and social dimensions. This research delves into the utilization of Circu…
View article: Developing Climate-Resilient and Sustainable Housing in Pakistan: Challenges and Opportunities
Developing Climate-Resilient and Sustainable Housing in Pakistan: Challenges and Opportunities Open
The housing sector has been globally affected by climate change. To mitigate the impacts, there is an urgent need to revise housing strategies to combat these challenges and increase the overall resilience of the built environment. Houses …
View article: To Study the Impact of Sociodemographic Factors on Glycemic Control of Children with Type I Diabetes Mellitus
To Study the Impact of Sociodemographic Factors on Glycemic Control of Children with Type I Diabetes Mellitus Open
Type 1 Diabetes Mellitus (T1DM) is a chronic autoimmune condition characterized by the destruction of insulin-producing beta cells in the pancreas, leading to lifelong dependence on insulin therapy. Objective: This study aims to identify t…
View article: Overview of menstrual hygiene management and other risk factors concerning bacterial vaginosis
Overview of menstrual hygiene management and other risk factors concerning bacterial vaginosis Open
Background Bangladesh is a developing nation where, for a variety of reasons, adequate female reproductive health is not maintained. A variety of health issues, including but not limited to bacterial vaginosis, pelvic inflammatory disease,…
View article: Overview of Menstrual Hygiene Management and Other Risk Factors concerning Bacterial Vaginosis
Overview of Menstrual Hygiene Management and Other Risk Factors concerning Bacterial Vaginosis Open
Background Bangladesh is a developing nation where, for a variety of reasons, adequate female reproductive health is not maintained. Bangladeshi women are plagued by a variety of nations and a variety assortment of reproductive tract disor…
View article: Phase 1/1b Dose Escalation and Expansion of CPX-351 in Combination with Gemtuzumab Ozogamicin in Newly Diagnosed Acute Myeloid Leukemia
Phase 1/1b Dose Escalation and Expansion of CPX-351 in Combination with Gemtuzumab Ozogamicin in Newly Diagnosed Acute Myeloid Leukemia Open
Introduction: Initial response to intensive chemotherapy in acute myeloid leukemia (AML) is about 50-60% and relapses are common. CPX-351, a dual-drug liposomal formulation of daunorubicin and cytarabine at the synergistic 1:5 molar ratio,…
View article: Trends and Disparities in Autoimmune Hemolytic Anemia-Related Mortality in the United States from 1999 to 2020: Insights from the CDC Wonder Database
Trends and Disparities in Autoimmune Hemolytic Anemia-Related Mortality in the United States from 1999 to 2020: Insights from the CDC Wonder Database Open
Introduction: Autoimmune hemolytic anemia (AIHA) is an acquired condition characterized by hemolysis due to autoantibodies against red blood cell antigens. AIHA can be categorized as primary, when the underlying cause has not been demonstr…
View article: Challenges, merits and demerits of curriculum co-creation in a private sector dental college: An interventional phenomenological study from Pakistan
Challenges, merits and demerits of curriculum co-creation in a private sector dental college: An interventional phenomenological study from Pakistan Open
This study explores co-creation practices in a Pakistani dental college to foster quality learner-teacher relationships and promote student empowerment. Co-creation as a model emphasizes shared decision-making and aims to create a more inc…
View article: Unstable Bilingualism between Hindko and Pashto in Hazar
Unstable Bilingualism between Hindko and Pashto in Hazar Open
Hindko and Pashto languages belong to the Indo-European language family, belonging to subgroups Indo-Aryan and Indo-Iranian respectively. In North West Frontier Region Pashto and Hindko co-exist side by side, gaining numbers of bilingual s…