Gun‐Woo Oh
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View article: Simple Fabrication and Biological Evaluation of Ulva australis-Derived Marine Carbon Dots with Anti-Inflammation, Anti-Oxidation, and Anti-Adipogenesis Features
Simple Fabrication and Biological Evaluation of Ulva australis-Derived Marine Carbon Dots with Anti-Inflammation, Anti-Oxidation, and Anti-Adipogenesis Features Open
The overabundance of Ulva australis (U. australis), a green macroalga widespread along the coastline of Jeju Island, Republic of Korea, presents a growing ecological challenge, as it can cause unpleasant odors and disturb the ecological ba…
View article: Antioxidant, Anti-Melanogenic, and Anti-Aging Activities of the Aqueous–Ethanolic Dry Extract of Rosa lucieae with Phytochemical Profiling
Antioxidant, Anti-Melanogenic, and Anti-Aging Activities of the Aqueous–Ethanolic Dry Extract of Rosa lucieae with Phytochemical Profiling Open
In this study, the cosmeceutical potential of a 70% ethanol extract of Rosa lucieae was investigated as a multifunctional bioactive ingredient. The extract was systematically evaluated for its antioxidant, anti-melanogenic, and anti-aging …
View article: Isolation and Characterization of a New Glycosylated Depside and Other Compounds with Antioxidant Activity from the Flower Buds of <i>Rosa rugosa</i>
Isolation and Characterization of a New Glycosylated Depside and Other Compounds with Antioxidant Activity from the Flower Buds of <i>Rosa rugosa</i> Open
Objectives This study focused on the isolation, structural elucidation, and free radical scavenging activities of compounds from the flower buds of Rosa rugosa . Methods The 30% ethanolic extract of R. rugosa was partitioned with organic s…
View article: Light-enhanced antibacterial carbon dot nanocomposite synthesized using Sargassum horneri and inorganic precursors
Light-enhanced antibacterial carbon dot nanocomposite synthesized using Sargassum horneri and inorganic precursors Open
This study aimed to introduce a novel antibacterial carbon dot-ZnO-TiO2 nanocomposite (CDZT) synthesized from the marine alga Sargassum horneri and two inorganic precursors. CDZT exhibited enhanced antibacterial activity under both ultravi…
View article: <i>Neptunea cumingii</i> Extract Inhibits Adipogenesis and Stimulates Browning of Adipocytes in 3T3‐L1 Preadipocytes
<i>Neptunea cumingii</i> Extract Inhibits Adipogenesis and Stimulates Browning of Adipocytes in 3T3‐L1 Preadipocytes Open
This study investigates the potential antiobesity effects of Neptunea cumingii extract (NCE). Our findings illustrate that NCE effectively reduces lipid accumulation and triglyceride content, while simultaneously increasing free glycerol r…
View article: An undescribed anti-inflammatory meroterpenoid from the brown alga <i>Sargassum macrocarpum</i>
An undescribed anti-inflammatory meroterpenoid from the brown alga <i>Sargassum macrocarpum</i> Open
View article: Phenolic-enriched Rosa rugosa extract ameliorates obesity-associated metabolic disorders and regulates gut microbiota in high-fat diet-fed mice
Phenolic-enriched Rosa rugosa extract ameliorates obesity-associated metabolic disorders and regulates gut microbiota in high-fat diet-fed mice Open
Obesity is a deleterious medical condition that can lead to lipid metabolism dysregulation and various metabolic disorders. The lipid-reducing and hypoglycemic effects of Rosa rugosa have been demonstrated both in vitro and in vivo. Howeve…
View article: Green Medicine: Advancing Antimicrobial Solutions with Diverse Terrestrial and Marine Plant-Derived Compounds
Green Medicine: Advancing Antimicrobial Solutions with Diverse Terrestrial and Marine Plant-Derived Compounds Open
Infectious diseases continue to cause global morbidity and mortality. The rise of drug-resistant pathogens is a major challenge to modern medicine. Plant-based antimicrobials may solve this issue; hence, this review discussed in detail pla…
View article: Characterization of flavonoid and quinic acid derivatives from Calystegia soldanella with antioxidant activities
Characterization of flavonoid and quinic acid derivatives from Calystegia soldanella with antioxidant activities Open
Calystegia soldanella is a species broadly used in an edible source and traditional herb in South Korea and China. It has diverse bioactivities, such as dropsy, antipyretic, and diuretic effect. In this study, we investigated the main comp…
View article: From Sea to Lab: Angiotensin I-Converting Enzyme Inhibition by Marine Peptides—Mechanisms and Applications
From Sea to Lab: Angiotensin I-Converting Enzyme Inhibition by Marine Peptides—Mechanisms and Applications Open
To reveal potent ACE inhibitors, researchers screen various bioactive peptides from several sources, and more attention has been given to aquatic sources. This review summarizes the recent research achievements on marine peptides with ACE-…
View article: Therapeutic Effect of Decellularized Extracellular Matrix from Fish Skin for Accelerating Skin Regeneration
Therapeutic Effect of Decellularized Extracellular Matrix from Fish Skin for Accelerating Skin Regeneration Open
A cellular matrix derived from natural tissue functions as a highly biocompatible and versatile material for wound healing application. It provides a complex and highly organized environment with biological molecules and physical stimuli. …
View article: <i>Strongylocentrotus intermedius</i> Extract Suppresses Adiposity by Inhibiting Adipogenesis and Promoting Adipocyte Browning via AMPK Activation in 3T3-L1 Cells
<i>Strongylocentrotus intermedius</i> Extract Suppresses Adiposity by Inhibiting Adipogenesis and Promoting Adipocyte Browning via AMPK Activation in 3T3-L1 Cells Open
The current study aimed to determine whether Strongylocentrotus intermedius (S. intermedius) extract (SIE) exerts anti-obesity potentials employing 3T3-L1 cells as in vitro model. Herein we reported that treatment of SIE for …
View article: Biocompatibility and sub-chronic toxicity studies of phlorotannin/polycaprolactone coated trachea tube for advancing medical device applications
Biocompatibility and sub-chronic toxicity studies of phlorotannin/polycaprolactone coated trachea tube for advancing medical device applications Open
View article: Brown Algae Dictyopteris divaricata Attenuates Adipogenesis by Modulating Adipocyte Differentiation and Promoting Lipolysis through Heme Oxygenase-1 Activation in 3T3-L1 Cells
Brown Algae Dictyopteris divaricata Attenuates Adipogenesis by Modulating Adipocyte Differentiation and Promoting Lipolysis through Heme Oxygenase-1 Activation in 3T3-L1 Cells Open
The present study aims to explore the probable anti-adipogenesis effect of Dictyopteris divaricata (D. divaricata) in 3T3-L1 preadipocytes by regulating heme oxygenase-1 (HO-1). The extract of D. divaricata retarded lipid accretion and dec…
View article: Strongylocentrotus Intermedius Extract Suppresses Adiposity by Inhibiting Adipogenesis and Promoting Adipocyte Browning Via Ampk Activation in 3t3-L1 Cells
Strongylocentrotus Intermedius Extract Suppresses Adiposity by Inhibiting Adipogenesis and Promoting Adipocyte Browning Via Ampk Activation in 3t3-L1 Cells Open
View article: Two New Meroterpenoid Derivatives From <i>Sargassum macrocarpum</i> With Their Anti-Oxidant Activities
Two New Meroterpenoid Derivatives From <i>Sargassum macrocarpum</i> With Their Anti-Oxidant Activities Open
Objective: The purpose of this study was to search for novel secondary metabolites present in the marine brown alga, Sargassum macrocarpum C. Agardh. Methods: The methanolic extract of S. macrocarpum was partitioned and fractionated using …
View article: Angiotensin I-Converting Enzyme (ACE) Inhibition and Molecular Docking Study of Meroterpenoids Isolated from Brown Alga, Sargassum macrocarpum
Angiotensin I-Converting Enzyme (ACE) Inhibition and Molecular Docking Study of Meroterpenoids Isolated from Brown Alga, Sargassum macrocarpum Open
Angiotensin I-converting enzyme (ACE) is an important blood pressure regulator. In this study, we aimed to investigate the ACE-inhibitory effects of meroterpenoids isolated from the brown alga, Sargassum macrocarpum, and the molecular mech…
View article: Tyrosinase inhibitory and antioxidant potential of eckmaxol isolated from the brown seaweed Ecklonia maxima
Tyrosinase inhibitory and antioxidant potential of eckmaxol isolated from the brown seaweed Ecklonia maxima Open
Eckmaxol is a natural compound isolated from the brown alga Ecklonia maxima and has been proposed to inhibit tyrosinase. The aim of the present study was to investigate the antioxidant and tyrosinase inhibitory activities of eckmaxol isola…
View article: Sargassumin C, a Novel Butenolide from <i>Sargassum micracanthum</i>
Sargassumin C, a Novel Butenolide from <i>Sargassum micracanthum</i> Open
Objective: In our ongoing effort to search for the novel secondary metabolites from the marine algae, chemical investigation of a methanolic extract of Sargassum micracanthum led to the isolation of a novel butenolide (1) and a known compo…
View article: Antioxidant, anti-inflammatory, and antibacterial activities of a 70% ethanol-Symphyocladia linearis extract
Antioxidant, anti-inflammatory, and antibacterial activities of a 70% ethanol-Symphyocladia linearis extract Open
Research on the potential biological activity of red alga Symphyocladia spp. has been limited to Symphyocladia latiuscula, which is widely used as a food ingredient in Korea. Here, we examined the biological activity of another species, Sy…
View article: Isolation and Characterization of Efficient Active Compounds Using High-Performance Centrifugal Partition Chromatography (CPC) from Anti-Inflammatory Activity Fraction of Ecklonia maxima in South Africa
Isolation and Characterization of Efficient Active Compounds Using High-Performance Centrifugal Partition Chromatography (CPC) from Anti-Inflammatory Activity Fraction of Ecklonia maxima in South Africa Open
Ecklonia maxima is a brown seaweed, which is abundantly distributed in South Africa. This study investigated an efficient approach using high-performance centrifugal partition chromatography (HPCPC), which has been successfully developed f…
View article: Antihypertensive Effects of IGTGIPGIW Peptide Purified from Hippocampus abdominalis: p-eNOS and p-AKT Stimulation in EA.hy926 Cells and Lowering of Blood Pressure in SHR Model
Antihypertensive Effects of IGTGIPGIW Peptide Purified from Hippocampus abdominalis: p-eNOS and p-AKT Stimulation in EA.hy926 Cells and Lowering of Blood Pressure in SHR Model Open
The aim of this study was to assess the potential hypertensive effects of the IGTGIPGIW peptide purified from Hippocampus abdominalis alcalase hydrolysate (HA) for application in the functional food industry. We investigated the antihypert…
View article: A 3D-Printed Polycaprolactone/Marine Collagen Scaffold Reinforced with Carbonated Hydroxyapatite from Fish Bones for Bone Regeneration
A 3D-Printed Polycaprolactone/Marine Collagen Scaffold Reinforced with Carbonated Hydroxyapatite from Fish Bones for Bone Regeneration Open
In bone tissue regeneration, extracellular matrix (ECM) and bioceramics are important factors, because of their osteogenic potential and cell–matrix interactions. Surface modifications with hydrophilic material including proteins show sign…
View article: Fucoidan Isolated from Sargassum confusum Suppresses Inflammatory Responses and Oxidative Stress in TNF-α/IFN-γ- Stimulated HaCaT Keratinocytes by Activating Nrf2/HO-1 Signaling Pathway
Fucoidan Isolated from Sargassum confusum Suppresses Inflammatory Responses and Oxidative Stress in TNF-α/IFN-γ- Stimulated HaCaT Keratinocytes by Activating Nrf2/HO-1 Signaling Pathway Open
Recent studies have revealed that marine brown seaweeds contain numerous bioactive compounds which exhibit various bioactivities. The present study investigated the effect of low molecular weight fucoidan (SCF) isolated from Sargassum conf…
View article: Anti-Allergic Effect of Low Molecular Weight Digest from Abalone Viscera on Atopic Dermatitis-Induced NC/Nga
Anti-Allergic Effect of Low Molecular Weight Digest from Abalone Viscera on Atopic Dermatitis-Induced NC/Nga Open
Abalone viscera (AV) is one of the byproducts of the seafood processing industry. The low molecular weight (<5 kDa) peptides (LMW-AV) obtained from gastrointestinal digestion of AV could suppress allergenic responses on activated HMC-1 hum…
View article: Applications of Marine Organism-Derived Polydeoxyribonucleotide: Its Potential in Biomedical Engineering
Applications of Marine Organism-Derived Polydeoxyribonucleotide: Its Potential in Biomedical Engineering Open
Polydeoxyribonucleotides (PDRNs) are a family of DNA-derived drugs with a molecular weight ranging from 50 to 1500 kDa, which are mainly extracted from the sperm cells of salmon trout or chum salmon. Many pre-clinical and clinical studies …
View article: A Review of Marine Algae-derived Therapeutic Agents for Respiratory Disease Asthma
A Review of Marine Algae-derived Therapeutic Agents for Respiratory Disease Asthma Open
View article: A Study on the Analysis of Safety Standard and Evaluation of Safety Performance for the 5 Nm3/hr Class Alkaline Water Electrolysis System
A Study on the Analysis of Safety Standard and Evaluation of Safety Performance for the 5 Nm3/hr Class Alkaline Water Electrolysis System Open
View article: Biological activities and biomedical potential of sea cucumber (Stichopus japonicus): a review
Biological activities and biomedical potential of sea cucumber (Stichopus japonicus): a review Open
Members of the phylum Echinodermata, commonly known as echinoderms, are exclusively marine invertebrates. Among the Echinodermata, sea cucumber belongs to the family Holothuroidea. The sea cucumber Stichopus (Apostichous) japonicus (Selenk…
View article: A heptameric peptide purified from Spirulina sp. gastrointestinal hydrolysate inhibits angiotensin I-converting enzyme- and angiotensin II-induced vascular dysfunction in human endothelial cells
A heptameric peptide purified from Spirulina sp. gastrointestinal hydrolysate inhibits angiotensin I-converting enzyme- and angiotensin II-induced vascular dysfunction in human endothelial cells Open
In this study, a marine microalga Spirulina sp.-derived protein was hydrolyzed using gastrointestinal enzymes to produce an angiotensin I (Ang I)-converting enzyme (ACE) inhibitory peptide. Following consecutive purification, the potent AC…