Mohammad Taghi Goodarzi
YOU?
Author Swipe
View article: Differential Expression of Galectin‐3, Caspase‐1, and Phosphorylated P53: Diagnostic Biomarkers for Basal Cell Carcinoma: A Case‐Control Study
Differential Expression of Galectin‐3, Caspase‐1, and Phosphorylated P53: Diagnostic Biomarkers for Basal Cell Carcinoma: A Case‐Control Study Open
Background and Aims Basal cell carcinoma (BCC) is a common form of skin cancer. By considering the role of Galectin‐3 (Gal‐3), Caspase‐1, and Phosphorylated p53 (pP53), they might have an essential role in BCC development. This study aimed…
View article: Enhanced immunogenicity of COVID-19 RBD fused to mutant scorpion's phospholipase D for vaccine development
Enhanced immunogenicity of COVID-19 RBD fused to mutant scorpion's phospholipase D for vaccine development Open
View article: Targeted pancreatic cancer therapy using 4-farnesyloxycoumarin conjugated nanocrystalline cellulose and Chitosan nanoparticles
Targeted pancreatic cancer therapy using 4-farnesyloxycoumarin conjugated nanocrystalline cellulose and Chitosan nanoparticles Open
This study investigates the effects of 4-farnesyloxycoumarin (4-FOC)-conjugated NCC/CTAB/CS nanoparticles (NPs) on PANC-1 pancreatic cancer cells, highlighting their cytotoxicity and antioxidant properties. Dynamic light scattering (DLS) a…
View article: Digital papillary adenocarcinoma: A case report of a rare malignant tumour with recommendations on management and follow-up
Digital papillary adenocarcinoma: A case report of a rare malignant tumour with recommendations on management and follow-up Open
Histological and immunohistochemical analysis (including HPV42 detection), SLNB, and radical excision or amputation are optimal for DPAC management. Long-term follow-up, possibly using melanoma criteria, is crucial. Further research is nee…
View article: Investigation of structure, optical, and photothermal properties in MoS2/Fe3O4/CuS nanocomposite for doxorubicin delivery
Investigation of structure, optical, and photothermal properties in MoS2/Fe3O4/CuS nanocomposite for doxorubicin delivery Open
View article: Improvement photothermal property of MoS2/Fe3O4/GNR nanocomposite in cancer treatment
Improvement photothermal property of MoS2/Fe3O4/GNR nanocomposite in cancer treatment Open
The objective of the present study was to develop a novel molybdenum disulfide/iron oxide/gold nanorods (MoS2/Fe3O4/GNR) nanocomposite (MFG) with different concentrations of AgNO3 solution (MFG1,…
View article: The silibinin-loaded Zein-β cyclodextrin nano-carriers (SZBC-NCs) as a novel selective cancer cell drug delivery system in HT-29 cell line
The silibinin-loaded Zein-β cyclodextrin nano-carriers (SZBC-NCs) as a novel selective cancer cell drug delivery system in HT-29 cell line Open
View article: Single-Nucleotide Polymorphism of rs11061971 (+219 A>T) in Adiponectin Receptor 2 (AdipoR2) Gene and its Association with Risk of Type 2 Diabetes among Iranian Population
Single-Nucleotide Polymorphism of rs11061971 (+219 A>T) in Adiponectin Receptor 2 (AdipoR2) Gene and its Association with Risk of Type 2 Diabetes among Iranian Population Open
Single-Nucleotide Polymorphism of rs11061971 (+219 A>T) in Adiponectin Receptor 2 (AdipoR2) Gene and its Association with Risk of Type 2 Diabetes among Iranian Population
View article: Attenuation of Differentiation of Mesenchymal Stem Cells Into Adipocytes by Co-administration of Calcium and All-trans Retinoic Acid
Attenuation of Differentiation of Mesenchymal Stem Cells Into Adipocytes by Co-administration of Calcium and All-trans Retinoic Acid Open
Background: Adipogenesis is affected by multiple factors, among which all-trans retinoic acid (ATRA) and Ca2+are considered important factors. Objectives: This study aimed to evaluate the effect of calcium, ATRA, and their underlying molec…
View article: The Oxidative and Cytotoxic Effects of Resveratrol Compared With Cisplatin in the LNCap Prostate Cancer Cell Line
The Oxidative and Cytotoxic Effects of Resveratrol Compared With Cisplatin in the LNCap Prostate Cancer Cell Line Open
Introduction: Prostate cancer is one of the most common diseases worldwide, and many efforts are made to treat this disease; however, these efforts seem to be futile. Accordingly, this study tends to compare the cytotoxic and oxidative (as…
View article: Effects of curcumin and metformin on oxidative stress and apoptosis in heart tissue of type 1 diabetic rats
Effects of curcumin and metformin on oxidative stress and apoptosis in heart tissue of type 1 diabetic rats Open
Introduction: Hyperglycemia enhances oxidative stress and apoptosis and induces damages in heart tissue. Based on antioxidant properties of curcumin and metformin, we hypothesized that these agents may exhibit cardioprotective effects by a…
View article: The effects of metformin monotherapy and combination of metformin and glibenclamide therapy on the expression of RAGE, Sirt1, and Nrf2 genes in peripheral blood mononuclear cells of type 2 diabetic patients
The effects of metformin monotherapy and combination of metformin and glibenclamide therapy on the expression of RAGE, Sirt1, and Nrf2 genes in peripheral blood mononuclear cells of type 2 diabetic patients Open
View article: TLR2 and TLR4 Signaling Pathways and Gastric Cancer: Insights from Transcriptomics and Sample Validation
TLR2 and TLR4 Signaling Pathways and Gastric Cancer: Insights from Transcriptomics and Sample Validation Open
Our findings suggested that molecules involved in inflammation, including TLR4 and its related pro-inflammatory cytokines, may be responsible for the development and progression of GC. Accordingly, the control of H. pylori infection reduce…
View article: Aqueous Garlic Extract Alleviates Oxidative Stress and Inflammation in Retinal Tissue of Rats with Diabetes Type 2
Aqueous Garlic Extract Alleviates Oxidative Stress and Inflammation in Retinal Tissue of Rats with Diabetes Type 2 Open
Aqueous Garlic Extract Alleviates Oxidative Stress and Inflammation in Retinal Tissue of Rats with Diabetes Type 2
View article: Anti-inflammatory and Antioxidant Properties of PLGA Nanoparticles Produced From Kombucha Extract on A2780 Human Ovarian Cancer Cell Line
Anti-inflammatory and Antioxidant Properties of PLGA Nanoparticles Produced From Kombucha Extract on A2780 Human Ovarian Cancer Cell Line Open
Background: Anti-cancer agents encapsulated in nanoparticles (NPs) can result in higher efficiency. Kombucha is a fermented tea beverage, and previous reports support its anti-cancer properties. Objectives: The present study aimed to evalu…
View article: Impacts of garlic extract on testicular oxidative stress and sperm characteristics in type 1 and 2 diabetic rats: An experimental study
Impacts of garlic extract on testicular oxidative stress and sperm characteristics in type 1 and 2 diabetic rats: An experimental study Open
Background: Hyperglycemia damages various tissues such as the testes through oxidative stress and inflammation, which can eventually lead to infertility. Objective: Garlic extract effects on the testicular tissue of diabetic rats were inve…
View article: Favorable effects of Anethum graveolens on liver oxidative stress and cholesterol 7 alpha-hydroxylase levels in non-alcoholic fatty liver disease (NAFLD) rat models
Favorable effects of Anethum graveolens on liver oxidative stress and cholesterol 7 alpha-hydroxylase levels in non-alcoholic fatty liver disease (NAFLD) rat models Open
View article: Quantitative Structure-Activity Relationships and Molecular Docking Simulation of Allicin Compounds as Inhibitors of COVID-19 Protease Enzyme
Quantitative Structure-Activity Relationships and Molecular Docking Simulation of Allicin Compounds as Inhibitors of COVID-19 Protease Enzyme Open
Background: Coronavirus (CoV) is a group of viruses that cause disease in humans and animals. These viruses contain crown-shaped spike glycoproteins on their surface. Objective: We conducted a quantitative structure-activity relationship (…
View article: Single-Nucleotide Polymorphism of rs11061971 (+219 A>T) in Adiponectin Receptor 2 (AdipoR2) Gene and Its Association with Risk of Type 2 Diabetes Among an Iranian Population
Single-Nucleotide Polymorphism of rs11061971 (+219 A>T) in Adiponectin Receptor 2 (AdipoR2) Gene and Its Association with Risk of Type 2 Diabetes Among an Iranian Population Open
Genetic modifications in the adiponectin receptor 2 (AdipoR2) gene can affect phenotypes associated with insulin resistance and diabetes. The purpose of this study was to evaluate the possible role of genetic modifications in the AdipoR2 g…
View article: Changes in serum levels of CEA and CA19-9 tumor markers in different stages of patients with colorectal cancer
Changes in serum levels of CEA and CA19-9 tumor markers in different stages of patients with colorectal cancer Open
Background: Colorectal cancer is one of the most common gastrointestinal cancers worldwide with a high prevalence among middle-aged people. This study aimed to evaluate and compare changes in serum levels of carcinoembryonic antigen (CEA) …
View article: Association of ADIPOQ rs266729 and rs1501299 gene polymorphisms and circulating adiponectin level with the risk of type 2 diabetes in a population of Iran: a case-control study
Association of ADIPOQ rs266729 and rs1501299 gene polymorphisms and circulating adiponectin level with the risk of type 2 diabetes in a population of Iran: a case-control study Open
View article: Clinicopathological, Immunohistochemical, and <i>PMS2 </i>Gene Expression Profiling of Patients with Sporadic Colorectal Cancer
Clinicopathological, Immunohistochemical, and <i>PMS2 </i>Gene Expression Profiling of Patients with Sporadic Colorectal Cancer Open
Background: The DNA mismatch repair (MMR) system is one of the molecular pathways involved in colorectal cancer (CRC) carcinogenesis that consists of several genes, including MLH1 (MutL homolog 1), MSH6 (MutS homolog 6), MSH2 (MutS homolog…
View article: Ameliorative Effect Of Trigonella Foenum Graecum L. On Lipid Profile, Liver Histology and Ldl-Receptor Gene Expression in High Cholesterol-Fed Hamsters
Ameliorative Effect Of Trigonella Foenum Graecum L. On Lipid Profile, Liver Histology and Ldl-Receptor Gene Expression in High Cholesterol-Fed Hamsters Open
A significant reduction was observed in serum triglyceride (p<0.01), total cholesterol, low and very low density cholesterol, aspartate and alanine transaminases in HCD+FG8 group (p<0.05) compared with HCD group, while serum level of HDL-c…
View article: Garlic extract attenuates retinal oxidative stress and IL-1 expression in STZ-induced diabetic rats
Garlic extract attenuates retinal oxidative stress and IL-1 expression in STZ-induced diabetic rats Open
Retinopathy is one of the most common complications of diabetes. Hyperglycemia damages to the tissues through induction of oxidative stress and inflammation. In this study, the effects of garlic extract on the oxidative stress status and i…
View article: Association between breast milk adipokines with growth in breast feeding infants, a systematic review and meta-analysis
Association between breast milk adipokines with growth in breast feeding infants, a systematic review and meta-analysis Open
Objectives Breast milk adipokines are associated with growth, body mass index (BMI) and weight gain in infants. In this study, the effect of breastmilk adipokines (leptin and adiponectin) on the BMI and weight gain of breast-fed infants wa…
View article: Evaluating the effect of arachidonic acid and eicosapentaenoic acid on induction of adipogenesis in human adipose-derived stem cells.
Evaluating the effect of arachidonic acid and eicosapentaenoic acid on induction of adipogenesis in human adipose-derived stem cells. Open
The result indicates a positive effect of omega-6 versus omega-3 in stimulating the pathways of adipogenesis.
View article: Anethum graveolens L. Alleviates Sperm Damage by Limiting Oxidative Stress and Insulin Resistance in Diabetic Rats
Anethum graveolens L. Alleviates Sperm Damage by Limiting Oxidative Stress and Insulin Resistance in Diabetic Rats Open
Background: It has been reported that diabetes is associated with sperm damage and infertility. Objective: The purpose of this experiment was to survey the effect of Anethum graveolens L . ( Dill ) powder on sperm profiles, oxidative stre…
View article: Relationship Between Breast Milk Ghrelin and Infants’ Serum Ghrelin and Growth in Breastfeeding Infants: A Systematic Review and Meta-Analysis
Relationship Between Breast Milk Ghrelin and Infants’ Serum Ghrelin and Growth in Breastfeeding Infants: A Systematic Review and Meta-Analysis Open
Relationship Between Breast Milk Ghrelin and Infants’ Serum Ghrelin and Growth in Breastfeeding Infants: A Systematic Review and Meta-Analysis
View article: The Possible Protective Effect of Resveratrol on DiazinonInduced Oxidative Stress and Hepatic Injury
The Possible Protective Effect of Resveratrol on DiazinonInduced Oxidative Stress and Hepatic Injury Open
Diazinon, one of the most known organophosphate pesticides (OPs), has harmful effects on human organs. Acetylcholinesterase inhibition, oxidative stress, and inflammation are the major mechanisms of diazinon toxicity. Diazinon has several …
View article: Comparison of Salivary Peroxidase in HIV Positive Patients and Healthy Controls: A Case-Control Study
Comparison of Salivary Peroxidase in HIV Positive Patients and Healthy Controls: A Case-Control Study Open
Comparison of Salivary Peroxidase in HIV Positive Patients and Healthy Controls: A Case-Control Study