Tomokatsu Hori
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View article: Detectability in Scalp EEGs of Epileptic Spikes Emitted from Brain Electrical Sources of Different Sizes and Locations: A Simulation Study Using Realistic Head Models of Elderly Adults
Detectability in Scalp EEGs of Epileptic Spikes Emitted from Brain Electrical Sources of Different Sizes and Locations: A Simulation Study Using Realistic Head Models of Elderly Adults Open
Background. Epilepsy is prevalent in the elderly, whose brain morphologies and skull electrical characteristics differ from those of younger adults. Here, using a multivariate definition of signal-to-noise ratio (SNR), we explored the dete…
View article: Fiber Tractography Analysis Applied to Transcranial MR-guided Focused Ultrasound Surgery (TcMRgFUS)
Fiber Tractography Analysis Applied to Transcranial MR-guided Focused Ultrasound Surgery (TcMRgFUS) Open
Transcranial MR-guided focused ultrasound surgery (TcMRgFUS) is recognized as a minimally invasive treatment method for essential tremor (ET), a condition characterized by involuntary motor disturbances. The target region for treating ET i…
View article: Abolition of seizures following Forel‐H‐tomy for drug‐resistant epilepsy: A case report
Abolition of seizures following Forel‐H‐tomy for drug‐resistant epilepsy: A case report Open
A 62‐year‐old female experienced an extensive cerebral contusion in the left frontotemporal lobe due to an acute subdural hematoma at the age of 44 years. Six months after the injury, the patient developed epileptic seizures. The seizures …
View article: Subtemporal Multiple Hippocampal Transection with/without CA1-Subiculum Disconnection for Medically Intractable Temporal Lobe Epilepsy
Subtemporal Multiple Hippocampal Transection with/without CA1-Subiculum Disconnection for Medically Intractable Temporal Lobe Epilepsy Open
Transsylvian selective amygdalohippocampectomy resulted in postoperative verbal memory decline in patients with mesial temporal lobe epilepsy of the language-dominant side. Mapping whole-brain connectivity changes have been studied recentl…
View article: Variable histopathology features of neuronal dyslamination in the cerebral neocortex adjacent to epilepsy‐associated vascular malformations suggest complex pathogenesis of focal cortical dysplasia ILAE type IIIc
Variable histopathology features of neuronal dyslamination in the cerebral neocortex adjacent to epilepsy‐associated vascular malformations suggest complex pathogenesis of focal cortical dysplasia ILAE type IIIc Open
Focal cortical dysplasia type IIIc (FCD‐IIIc) is histopathologically defined by the International League Against Epilepsy's classification scheme as abnormal cortical organization adjacent to epilepsy‐associated vascular malformations (VM)…
View article: HOP protein expression in the hippocampal dentate gyrus is acutely downregulated in a status epilepticus mouse model
HOP protein expression in the hippocampal dentate gyrus is acutely downregulated in a status epilepticus mouse model Open
Status epilepticus (SE) is a neurological emergency, and delayed management can lead to higher morbidity and mortality. It is thought that prolonged seizures stimulate stem cells in the hippocampus and that epileptogenesis may arise from a…
View article: Comorbid seizure reduction after pallidothalamic tractotomy for movement disorders: Revival of Jinnai’s Forel‐H‐tomy
Comorbid seizure reduction after pallidothalamic tractotomy for movement disorders: Revival of Jinnai’s Forel‐H‐tomy Open
Forel‐H‐tomy for intractable epilepsy was introduced by Dennosuke Jinnai in the 1960s. Recently, Forel‐H‐tomy was renamed to “pallidothalamic tractotomy” and revived for the treatment of Parkinson's disease and dystonia. Two of our patient…
View article: Effects of Ferulic Acid and <i>Angelica archangelica</i> Extract (Feru-guard<sup> ®</sup>) on Mild Cognitive Impairment: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Prospective Trial
Effects of Ferulic Acid and <i>Angelica archangelica</i> Extract (Feru-guard<sup> ®</sup>) on Mild Cognitive Impairment: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Prospective Trial Open
We conducted a multicenter, randomized, double-blind, placebo-controlled prospective trial examining a supplement containing ferulic acid and Angelica archangelica extract (Feru-guard ® ) for mild cognitive impairment (MCI). In the intenti…
View article: Magnetic resonance-guided focused ultrasound for mesial temporal lobe epilepsy: a case report
Magnetic resonance-guided focused ultrasound for mesial temporal lobe epilepsy: a case report Open
Background We report the first case of transcranial magnetic resonance-guided focused ultrasound (MRgFUS) for mesial temporal lobe epilepsy (MTLE). Case presentation The target was located 20 mm lateral from the midline and 15 mm above the…
View article: Analysis of proliferating neuronal progenitors and immature neurons in the human hippocampus surgically removed from control and epileptic patients
Analysis of proliferating neuronal progenitors and immature neurons in the human hippocampus surgically removed from control and epileptic patients Open
Adult neurogenesis in the mammalian hippocampus is a well-known phenomenon. However, it remains controversial as to what extent adult neurogenesis actually occurs in the adult human hippocampus, and how brain diseases, such as epilepsy, af…
View article: Placental alkaline phosphatase levels in cerebrospinal fluid can have a decisive role in the differential diagnosis of intracranial germ cell tumors
Placental alkaline phosphatase levels in cerebrospinal fluid can have a decisive role in the differential diagnosis of intracranial germ cell tumors Open
OBJECTIVE Placental alkaline phosphatase (PLAP) in CSF can provide a very high diagnostic value in cases of intracranial germ cell tumors (GCTs), especially in pure germinomas, to the level of not requiring histological confirmation. Unlik…
View article: Surgical Resection of Hemangioma Secondary to CyberKnife Treatment for Arteriovenous Malformation
Surgical Resection of Hemangioma Secondary to CyberKnife Treatment for Arteriovenous Malformation Open
High-grade cerebral arteriovenous malformations (AVMs) are too complex to be treated
View article: Extracranial Facial Nerve Schwannoma Treated by Hypo-fractionated CyberKnife Radiosurgery
Extracranial Facial Nerve Schwannoma Treated by Hypo-fractionated CyberKnife Radiosurgery Open
Facial nerve schwannoma is a rare intracranial tumor. Treatment for this benign tumor has been controversial. Here, we report a case of extracranial facial nerve schwannoma treated successfully by hypo-fractionated CyberKnife (Accuray, Sun…
View article: Utility of crankshaft clips for middle cerebral artery aneurysms: A single-center experience of 150 cases
Utility of crankshaft clips for middle cerebral artery aneurysms: A single-center experience of 150 cases Open
Crankshaft clips are useful and safe for clipping of complicated MCA aneurysms.
View article: Risk of rupture of unruptured cerebral aneurysms in elderly patients
Risk of rupture of unruptured cerebral aneurysms in elderly patients Open
In our pooled analysis of prospective cohorts in Japan, patient age and aneurysm size and location were significant risk factors for UCA rupture in elderly patients.
View article: Stent treatment for cerebral venous sinus thrombosis with internal jugular vein stenosis: A case report
Stent treatment for cerebral venous sinus thrombosis with internal jugular vein stenosis: A case report Open
要旨：症例はくも膜下出血を発症した49 歳男性．右中大脳動脈瘤クリッピング術の後，内外減圧術を行い，いったん脳浮腫は軽快した．第17 日病日ごろより，両側後頭側頭頭頂葉を中心に脳浮腫が再度悪化し，鉤ヘルニアを来した．MR 静脈撮影より左S 状静脈洞血栓症と診断し未分画ヘパリンによる抗凝固療法を施行するも，症状がさらに悪化したため，第28 病日に血管内治療を行った．バルーンによる血管形成術を施行しても左内頸静脈に高度狭窄が残存し良好な順行性血流が得られなかったため，狭窄部に頸…