Taisen Iguchi
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View article: Identification of the estrogen receptor subtypes associated with testis-ova induction in the medaka
Identification of the estrogen receptor subtypes associated with testis-ova induction in the medaka Open
Exposure to estrogenic endocrine disrupting chemicals (EDCs) poses a significant threat to aquatic wildlife. They are known to induce a range of adverse reproductive and developmental disorders that include induction of oocytes in the test…
View article: Local immune response induced by intra-fin antigen injection in Japanese medaka (Oryzias latipes) is a useful model for immunological studies
Local immune response induced by intra-fin antigen injection in Japanese medaka (Oryzias latipes) is a useful model for immunological studies Open
Teleost fishes play a pivotal role in advancing our understanding of immune system evolution because they retain the ancient characteristics of vertebrate immunity, encompassing both innate and adaptive immune systems. Among these, innate …
View article: The Conflict between Regulatory Agencies over the 20,000-Fold Lowering of the Tolerable Daily Intake (TDI) for Bisphenol A (BPA) by the European Food Safety Authority (EFSA)
The Conflict between Regulatory Agencies over the 20,000-Fold Lowering of the Tolerable Daily Intake (TDI) for Bisphenol A (BPA) by the European Food Safety Authority (EFSA) Open
We strongly endorse EFSA's revised TDI for BPA and support the European Commission's (EC) apparent acceptance of this updated BPA risk assessment. We discuss challenges to current chemical risk assessment assumptions about EDCs that need t…
View article: Local Immune Response Induced by Intra-Fin Antigen Injection in Japanese Medaka (Oryzias Latipes) is a Useful Model for Immunological Studies
Local Immune Response Induced by Intra-Fin Antigen Injection in Japanese Medaka (Oryzias Latipes) is a Useful Model for Immunological Studies Open
View article: Issue Information
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View article: Issue Information
Issue Information Open
No abstract is available for this article.
View article: European Medicines Agency Conflicts With the European Food Safety Authority (EFSA) on Bisphenol A Regulation
European Medicines Agency Conflicts With the European Food Safety Authority (EFSA) on Bisphenol A Regulation Open
The European Food Safety Authority (EFSA) has revised their estimate of the toxicity of bisphenol A (BPA) and, as a result, have recommended reducing the tolerable daily intake (TDI) by 20 000-fold. This would essentially ban the use of BP…
View article: The role of mesenchymal estrogen receptor 1 in mouse uterus in response to estrogen
The role of mesenchymal estrogen receptor 1 in mouse uterus in response to estrogen Open
Estrogens play important roles in uterine growth and homeostasis through estrogen receptors (ESR1 and ESR2). To address the role of ESR1-mediated tissue events in the murine uterus, we analyzed mice with a mesenchymal tissue-specific knock…
View article: Comparative analysis of gonadal transcriptomes between turtle and alligator identifies common molecular cues activated during the temperature-sensitive period for sex determination
Comparative analysis of gonadal transcriptomes between turtle and alligator identifies common molecular cues activated during the temperature-sensitive period for sex determination Open
The mode of sex determination in vertebrates can be categorized as genotypic or environmental. In the case of genotypic sex determination (GSD), the sexual fate of an organism is determined by the chromosome composition with some having do…
View article: The role of mesenchymal estrogen receptor 1 in mouse uterus in response to estrogen
The role of mesenchymal estrogen receptor 1 in mouse uterus in response to estrogen Open
Estrogens play important roles in uterine growth and homeostasis through estrogen receptors (ESR1 and ESR2). To address the role of ESR1-mediated tissue events in the murine uterus, we analyzed mice with a mesenchymal tissue-specific knock…
View article: Evolutionary differentiation of androgen receptor is responsible for sexual characteristic development in a teleost fish
Evolutionary differentiation of androgen receptor is responsible for sexual characteristic development in a teleost fish Open
Teleost fishes exhibit complex sexual characteristics in response to androgens, such as fin enlargement and courtship display. However, the molecular mechanisms underlying their evolutionary acquisition remain largely unknown. To address t…
View article: Comparative Analysis of Gonadal Transcriptomes between Turtle and Alligator Identifies Common Molecular Cues Activated During the Temperature-Sensitive Period for Sex Determination
Comparative Analysis of Gonadal Transcriptomes between Turtle and Alligator Identifies Common Molecular Cues Activated During the Temperature-Sensitive Period for Sex Determination Open
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Issue Information Open
No abstract is available for this article.
View article: Adverse effects of thyroid-hormone-disrupting chemicals 6-propyl-2-thiouracil and tetrabromobisphenol A on Japanese medaka (Oryzias latipes)
Adverse effects of thyroid-hormone-disrupting chemicals 6-propyl-2-thiouracil and tetrabromobisphenol A on Japanese medaka (Oryzias latipes) Open
View article: Evolutionary differentiation of androgen receptor ohnologs is responsible for the development of androgen-dependent unique sexual characteristics in a teleost fish
Evolutionary differentiation of androgen receptor ohnologs is responsible for the development of androgen-dependent unique sexual characteristics in a teleost fish Open
Teleost fishes exhibit complex unique sexual characteristics, such as fin enlargement and courtship display, in response to androgens. However, the molecular mechanisms underlying their evolutionary acquisition remain largely unknown. To a…
View article: Larval Development of Non-Insect Arthropods: Metamorphosis and Sexual Differentiation
Larval Development of Non-Insect Arthropods: Metamorphosis and Sexual Differentiation Open
In insects, metamorphosis is one of the most important research topics. Their drastic morphological and physiological changes from larvae to pupae, and then to adults, have fascinated many people. These changing life history patterns are t…
View article: Arthropods - New Advances and Perspectives
Arthropods - New Advances and Perspectives Open
This book provides contributions on various topics pertaining to arthropods (insects and non-insects) written by experts in their respective fields. It targets a wide audience of entomologists, biologists, ecologists, zoologists, teachers,…
View article: <i>Gonadal Soma-Derived Factor</i> Expression is a Potential Biomarker for Predicting the Effects of Endocrine-Disrupting Chemicals on Gonadal Differentiation in Japanese Medaka (<i>Oryzias Latipes</i>)
<i>Gonadal Soma-Derived Factor</i> Expression is a Potential Biomarker for Predicting the Effects of Endocrine-Disrupting Chemicals on Gonadal Differentiation in Japanese Medaka (<i>Oryzias Latipes</i>) Open
Chemicals with androgenic or estrogenic activity induce the sex reversal and/or intersex condition in various teleost fish species. Previously, we reported that exposure to 17α-methyltestosterone, bisphenol A, or 4-nonylphenol induces chan…
View article: Summary of 17 chemicals evaluated by OECD TG229 using Japanese Medaka, <i>Oryzias latipes</i> in EXTEND 2016
Summary of 17 chemicals evaluated by OECD TG229 using Japanese Medaka, <i>Oryzias latipes</i> in EXTEND 2016 Open
In June 2016, the Ministry of the Environment of Japan announced a program “EXTEND2016” on the implementation of testing and assessment for endocrine active chemicals, consisting of a two‐tiered strategy. The aim of the Tier 1 screening an…
View article: Sex Determination and Differentiation in Decapod and Cladoceran Crustaceans: An Overview of Endocrine Regulation
Sex Determination and Differentiation in Decapod and Cladoceran Crustaceans: An Overview of Endocrine Regulation Open
Mechanisms underlying sex determination and differentiation in animals are known to encompass a diverse array of molecular clues. Recent innovations in high-throughput sequencing and mass spectrometry technologies have been widely applied …
View article: Summary of reference chemicals evaluated by the fish short‐term reproduction assay, OECD TG229, using Japanese Medaka, <scp><i>Oryzias latipes</i></scp>
Summary of reference chemicals evaluated by the fish short‐term reproduction assay, OECD TG229, using Japanese Medaka, <span><i>Oryzias latipes</i></span> Open
Under the Organisation for Economic Co‐operation and Development (OECD), the Ministry of the Environment of Japan (MOE) added Japanese medaka ( Oryzias latipes ) to the test guideline fish short‐term reproduction assay (FSTRA) developed by…
View article: Peer Review #1 of "Steroid hormones and chondrichthyan reproduction: physiological functions, scientific research, and implications for conservation (v0.1)"
Peer Review #1 of "Steroid hormones and chondrichthyan reproduction: physiological functions, scientific research, and implications for conservation (v0.1)" Open
The study of the reproductive aspects of chondrichthyans through the analysis of steroid hormones has been carried out for more than five decades in several species around the world.This scientific knowledge constitutes the basis of the re…
View article: Expression dynamics of genes in the hypothalamic-pituitary-thyroid (HPT) cascade and their responses to 3,3′,5-triiodo-l-thyronine (T3) highlights potential vulnerability to thyroid-disrupting chemicals in zebrafish (Danio rerio) embryo-larvae
Expression dynamics of genes in the hypothalamic-pituitary-thyroid (HPT) cascade and their responses to 3,3′,5-triiodo-l-thyronine (T3) highlights potential vulnerability to thyroid-disrupting chemicals in zebrafish (Danio rerio) embryo-larvae Open
View article: ERGO: Breaking Down the Wall between Human Health and Environmental Testing of Endocrine Disrupters
ERGO: Breaking Down the Wall between Human Health and Environmental Testing of Endocrine Disrupters Open
ERGO (EndocRine Guideline Optimization) is the acronym of a European Union-funded research and innovation action, that aims to break down the wall between mammalian and non-mammalian vertebrate regulatory testing of endocrine disruptors (E…
View article: A newly developed genetic sex marker and its application to understanding chemically induced feminisation in roach (<i>Rutilus rutilus</i>)
A newly developed genetic sex marker and its application to understanding chemically induced feminisation in roach (<i>Rutilus rutilus</i>) Open
Oestrogenic wastewater treatment works (WwTW) effluents discharged into UK rivers have been shown to affect sexual development, including inducing intersex, in wild roach ( Rutilus rutilus ). This can result in a reduced breeding capabilit…
View article: Estrogen Receptor β2 Oversees Germ Cell Maintenance and Gonadal Sex Differentiation in Medaka, Oryzias latipes
Estrogen Receptor β2 Oversees Germ Cell Maintenance and Gonadal Sex Differentiation in Medaka, Oryzias latipes Open
In vertebrates, estrogen receptors are essential for estrogen-associated early gonadal sex development. Our previous studies revealed sexual dimorphic expression of estrogen receptor β2 (ERβ2) during embryogenesis of medaka, and here we in…
View article: Molecular mechanisms and tissue targets of brominated flame retardants, BDE-47 and TBBPA, in embryo-larval life stages of zebrafish (Danio rerio)
Molecular mechanisms and tissue targets of brominated flame retardants, BDE-47 and TBBPA, in embryo-larval life stages of zebrafish (Danio rerio) Open
View article: The Role of Fgf Signaling on Epithelial Cell Differentiation in Mouse Vagina
The Role of Fgf Signaling on Epithelial Cell Differentiation in Mouse Vagina Open
FGF-ERK/MAPK pathway may be a main inducer of terminal differentiation in the mouse vaginal epithelium.
View article: Diethylstilbestrol Alters the Expression of Activins in the Neonatal Mouse Ovary <i>In Vitro</i>
Diethylstilbestrol Alters the Expression of Activins in the Neonatal Mouse Ovary <i>In Vitro</i> Open
Alterations in activin signaling are involved in the polyovular follicle induction by DES.
View article: Functional distinctions associated with the diversity of sex steroid hormone receptors ESR and AR
Functional distinctions associated with the diversity of sex steroid hormone receptors ESR and AR Open