Hitoshi Maruyama
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View article: Management of acute variceal bleeding: updated APASL guidelines
Management of acute variceal bleeding: updated APASL guidelines Open
View article: Liver disease trends in the Asia-Pacific region for the next 50 years
Liver disease trends in the Asia-Pacific region for the next 50 years Open
Liver disease has emerged as a critical and escalating public health concern worldwide, with the Asia-Pacific region at the forefront of this challenge due to its vast population and diverse socioeconomic landscape. Over the coming five de…
View article: Asian Conference on Tumor Ablation Guidelines for Hepatocellular Carcinoma
Asian Conference on Tumor Ablation Guidelines for Hepatocellular Carcinoma Open
Globally, the incidence and associated mortality of primary liver cancer have been steadily increasing. Currently, 80% of cases are found in Asia. Curative resection is applicable in only 20% of patients; therefore, various nonsurgical tre…
View article: Ablation manual for liver cancer
Ablation manual for liver cancer Open
View article: The relationship between the ratio of the supraspinatus muscle thickness measured by ultrasound imaging and glenohumeral subluxation in stroke patients: a cross-sectional study
The relationship between the ratio of the supraspinatus muscle thickness measured by ultrasound imaging and glenohumeral subluxation in stroke patients: a cross-sectional study Open
Introduction Glenohumeral subluxation (GHS) is a common complication in stroke patients with hemiplegia, occurring in approximately 17–81% of cases. This study aims to evaluate the relationship between shoulder muscle thickness and the deg…
View article: The Past, Future, and Innovation of Physical Therapy
The Past, Future, and Innovation of Physical Therapy Open
In Japan, the qualification of physical therapist was established in 1966. This was followed by the establishment of professional and academic associations for physical therapists, and these associations have been actively contributing to …
View article: Short-term intervention effect analysis of neuromuscular joint facilitation in patients who experienced stroke with shoulder subluxation: a clinical randomized controlled trial
Short-term intervention effect analysis of neuromuscular joint facilitation in patients who experienced stroke with shoulder subluxation: a clinical randomized controlled trial Open
[Purpose] Shoulder subluxation is a common complication of acute stroke that affects clinical rehabilitation training and hinders the recovery of upper limb motor function. This study explored the short-term interventional effects of neuro…
View article: Effect of expiratory muscle training on respiratory muscle fatigue in healthy adults: a randomized controlled trial
Effect of expiratory muscle training on respiratory muscle fatigue in healthy adults: a randomized controlled trial Open
[Purpose] This study examined the effects of expiratory muscle training on fatigue in individual respiratory muscles. [Participants and Methods] Healthy adult males (n=31) were randomly assigned to two groups: expiratory muscle training (n…
View article: Ablation Manual for Liver Cancer
Ablation Manual for Liver Cancer Open
近年のエネルギーデバイス技術の進歩により，アブレーションは飛躍的に普及した．本治療は外科手術に比べて侵襲性が抑えられ術後回復が早いことから，肝，肺，腎，甲状腺，骨軟部腫瘍など幅広い臓器に対して適応されるようになった．病変部に対して治療針を適切に誘導するためには画像による支援が必要であり，高分解能かつリアルタイム性を利点とする超音波は最も頻用されている映像技術である．すなわちアブレーションは，超音波の長所を最大限に生かした治療法と言える．本企画は，肝癌に対するアブレーションに…
View article: Obesity and non-alcoholic steatohepatitis in immunotherapy for hepatocellular carcinoma
Obesity and non-alcoholic steatohepatitis in immunotherapy for hepatocellular carcinoma Open
View article: Use of albumin infusion for cirrhosis-related complications: An international position statement
Use of albumin infusion for cirrhosis-related complications: An international position statement Open
View article: The Impact of Partial Splenic Embolization on Portal Hypertensive Gastropathy in Cirrhotic Patients with Portal Hypertension
The Impact of Partial Splenic Embolization on Portal Hypertensive Gastropathy in Cirrhotic Patients with Portal Hypertension Open
This study investigated the impact of partial splenic embolization (PSE) on portal hypertensive gastropathy (PHG). We retrospectively analyzed endoscopic findings and the portal venous system of 31 cirrhotic patients with PHG. The improved…
View article: Contrast-enhanced ultrasonography for the management of portal hypertension in cirrhosis
Contrast-enhanced ultrasonography for the management of portal hypertension in cirrhosis Open
Portal hypertension is a major pathophysiological condition in patients with cirrhosis. This accounts for the occurrence and severity of the various manifestations. The degree is determined by the portal pressure or hepatic venous pressure…
View article: Ablation for Benign Liver Tumors: Current Concepts and Limitations
Ablation for Benign Liver Tumors: Current Concepts and Limitations Open
Percutaneous ablation under imaging guidance is a curative treatment that can induce complete tumor necrosis with advantages of minimal invasiveness and a low risk of complications. Thermal ablation, which includes radiofrequency ablation …
View article: The RNA-Binding Protein ELAVL1 Regulates Hepatitis B Virus Replication and Growth of Hepatocellular Carcinoma Cells
The RNA-Binding Protein ELAVL1 Regulates Hepatitis B Virus Replication and Growth of Hepatocellular Carcinoma Cells Open
Previous RNA immunoprecipitation followed by proteomic approaches successfully demonstrated that Embryonic Lethal, Abnormal Vision, Drosophila-Like 1 (ELAVL1) interacts with hepatitis B virus (HBV)-derived RNAs. Although ELAVL family prote…
View article: Artisanry and ultrasound: a salty humor
Artisanry and ultrasound: a salty humor Open
View article: Hepatic venous pressure gradient (HVPG) measurement: Tips and pitfalls of hepatic venous catheterization
Hepatic venous pressure gradient (HVPG) measurement: Tips and pitfalls of hepatic venous catheterization Open
Portal hypertension is the main pathophysiology of chronic liver disease. The severity of portal hypertension depends on portal venous pressure, which is associated with various manifestations such as gastroesophageal varices, portal hyper…
View article: The Efficacy of Expiratory Muscle Training during Inspiratory Load in Healthy Adult Males: A Randomized Controlled Trial
The Efficacy of Expiratory Muscle Training during Inspiratory Load in Healthy Adult Males: A Randomized Controlled Trial Open
This study aimed to evaluate the effects of expiratory muscle training (EMT) on respiratory muscle strength and respiratory distress during inspiratory load. Thirty-one healthy adult males were randomly divided into an EMT group who underw…
View article: Body Fat Percentage and Normal-Weight Obesity in the Chinese Population: Development of a Simple Evaluation Indicator Using Anthropometric Measurements
Body Fat Percentage and Normal-Weight Obesity in the Chinese Population: Development of a Simple Evaluation Indicator Using Anthropometric Measurements Open
Few studies explore the associations between body fat percentage (BFP) prediction and evaluation indicators for Chinese with normal-weight obesity. We aimed to explore convenient and cost-free BFP evaluation indicators to routinely monitor…
View article: Effect of hip adduction/abduction contraction on pelvic floor in young healthy women
Effect of hip adduction/abduction contraction on pelvic floor in young healthy women Open
Pelvic floor muscle training has been reported to be effective in preventing and improving urinary incontinence. Patients must learn to perform pelvic floor muscle contractions without pushing down the pelvic floor by contracting other mus…
View article: Effect of Atezolizumab plus Bevacizumab in Patients with Hepatocellular Carcinoma Harboring <i>CTNNB1</i> Mutation in Early Clinical Experience
Effect of Atezolizumab plus Bevacizumab in Patients with Hepatocellular Carcinoma Harboring <i>CTNNB1</i> Mutation in Early Clinical Experience Open
Atezolizumab plus bevacizumab (ATZ/BV) treatment is a combined immunotherapy consisting of immune checkpoint inhibitor (ICI) and anti-vascular endothelial growth factor monoclonal antibody, which has brought a major paradigm shift in the t…
View article: Evaluation of supraspinatus muscle changes in the shoulder joint of stroke patients with hemiplegic and shoulder subluxation using ultrasonography: comparison between affected and unaffected sides
Evaluation of supraspinatus muscle changes in the shoulder joint of stroke patients with hemiplegic and shoulder subluxation using ultrasonography: comparison between affected and unaffected sides Open
[Purpose] The shoulder joint has a very unstable structure yet a significantly wide range of motion. Weakness of the muscles around the shoulder joint may cause shoulder joint subluxation. This study aimed to determine changes in supraspin…
View article: Immediate effects of neuromuscular joint-facilitation bridging exercises on walking ability and balance function in stroke patients
Immediate effects of neuromuscular joint-facilitation bridging exercises on walking ability and balance function in stroke patients Open
[Purpose] This study aimed to examine the immediate effects of a pelvic neuromuscular joint-facilitation intervention on the walking and balance ability of patients with hemiplegia caused by cerebrovascular accidents. [Participants and Met…
View article: The reliability and effectiveness of shoulder joint evaluation by ultrasonography in stroke patients: deltoid muscle thickness, acromion-humeral distance, acromion-lesser tuberosity distance
The reliability and effectiveness of shoulder joint evaluation by ultrasonography in stroke patients: deltoid muscle thickness, acromion-humeral distance, acromion-lesser tuberosity distance Open
[Purpose] This study aimed to evaluate the reliability of the intraclass correlation coefficient (ICC) in measuring deltoid muscle thickness (DMT) at different angles, acromion-humeral distance (AHD), and acromion nodule tuberosity (ALT) d…
View article: Verification of the Reliability and Validity of the Clinical Management Competencies Scale for Physical Therapists (CMCS-PT)
Verification of the Reliability and Validity of the Clinical Management Competencies Scale for Physical Therapists (CMCS-PT) Open
[Purpose] The purpose of this study was to clarify the competency factors of physical therapists involved in management work and to verify the reliability and validity of the Clinical Management Competencies Scale for physical therapists (…
View article: Evolution of Survival Impact of Molecular Target Agents in Patients with Advanced Hepatocellular Carcinoma
Evolution of Survival Impact of Molecular Target Agents in Patients with Advanced Hepatocellular Carcinoma Open
Background and Aims: The prognosis of patients with advanced hepatocellular carcinoma (HCC) is expected to improve as multiple molecular target agents (MTAs) are now available. However, the impact of the availability of seque…
View article: EZH1/2 inhibition augments the anti-tumor effects of sorafenib in hepatocellular carcinoma
EZH1/2 inhibition augments the anti-tumor effects of sorafenib in hepatocellular carcinoma Open
View article: Laparoscopic bypass surgery as palliative treatment for duodenal obstruction due to lymph node metastasis invasion of hepatocellular carcinoma
Laparoscopic bypass surgery as palliative treatment for duodenal obstruction due to lymph node metastasis invasion of hepatocellular carcinoma Open
症例は70歳男性．X－12年に肝細胞癌（HCC）を合併し，局所治療と再発を繰り返していた．X－1年に腹部リンパ節転移および肺転移が出現したため，ソラフェニブによる全身化学療法を開始した．しかしその後も病勢は進行し，リンパ節転移巣からの浸潤による高度な十二指腸狭窄を来し，経口摂取不能となった．消化器外科医との緊密な協議と患者に対する十分なインフォームドコンセントを行った上で，腹腔鏡下に胃・小腸バイパス術を施行した．術後経過は良好で，経口摂取が可能となり，自宅退院となった．その…
View article: Connection between HPS and ACLF: a solution of chaos?
Connection between HPS and ACLF: a solution of chaos? Open
View article: The RNA-Binding Protein ELAVL1 Regulates Hepatitis B Virus Replication And Growth of Hepatocellular Carcinoma Cells
The RNA-Binding Protein ELAVL1 Regulates Hepatitis B Virus Replication And Growth of Hepatocellular Carcinoma Cells Open
Previous RNA immunoprecipitation followed by proteomic approaches successfully demonstrated that Embryonic Lethal, Abnormal Vision, Drosophila-Like 1 (ELAVL1) interacts with hepatitis B virus (HBV)-derived RNAs. Although ELAVL family prote…