T. Lancefield
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Renal Medullary but Not Cerebral Hypoxia in a Large Animal Model of Heart Failure With Mildly Reduced Ejection Fraction Open
Background Chronic kidney disease and cognitive impairment are common in heart failure, but how changes in microcirculatory perfusion and oxygenation contribute to these complications remains unclear. We investigated how heart failure with…
View article: Promoting resilience to weather‐related and seasonal provocations to health in people with multimorbid heart disease: a prospective pragmatic, randomised trial
Promoting resilience to weather‐related and seasonal provocations to health in people with multimorbid heart disease: a prospective pragmatic, randomised trial Open
Objective To investigate whether a multifaceted intervention for building resilience to external provocations to health reduced the number of all‐cause hospital re‐admissions and deaths of people hospitalised with multimorbid heart disease…
View article: Abdominal aortic calcification on routine preoperative computed tomography—A novel cardiovascular risk prediction tool in liver transplant patients
Abdominal aortic calcification on routine preoperative computed tomography—A novel cardiovascular risk prediction tool in liver transplant patients Open
Cardiovascular (CV) disease is a leading cause of postoperative mortality following liver transplantation (LT). The presence of abdominal aortic calcification (AAC) has been linked to CV events in the general population. We sought to inves…
View article: Blunted cardiac reserve as a marker of cirrhotic cardiomyopathy—Cardiac outcomes following liver transplantation and comparison to the existing guidelines
Blunted cardiac reserve as a marker of cirrhotic cardiomyopathy—Cardiac outcomes following liver transplantation and comparison to the existing guidelines Open
Cirrhotic cardiomyopathy (CCM) is an underrecognized risk factor for cardiac events in patients undergoing liver transplantation (LT). Blunted cardiac reserve (BCR) is an emerging indicator of CCM, although it has not been integrated into …
Renal macro- and microcirculatory perturbations in acute kidney injury and chronic kidney disease associated with heart failure and cardiac surgery Open
Chronic kidney disease (CKD) affects 50% of patients with heart failure. The pathophysiology of CKD in heart failure is proposed to be driven by macrocirculatory hemodynamic changes, including reduced cardiac output and elevated central ve…
View article: Vulnerability to environmental and climatic health provocations among women and men hospitalized with chronic heart disease: insights from the RESILIENCE TRIAL cohort
Vulnerability to environmental and climatic health provocations among women and men hospitalized with chronic heart disease: insights from the RESILIENCE TRIAL cohort Open
Aims We aimed to recruit a representative cohort of women and men with multi-morbid chronic heart disease as part of a trial testing an innovative, nurse-co-ordinated, multi-faceted intervention to lower rehospitalization and death by addr…
Plasma desmosine, a biomarker of elastin degradation, predicts outcomes in coronary artery disease Open
Background Recent evidence from animal studies suggests that elastin degradation accelerates atherosclerosis and increases risk of plaque rupture and subsequent myocardial infarction and stroke. Desmosine is an elastin-specific degradation…
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Issue Information Open
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Good at heart: Developing a tertiary perinatal cardiac service; the first eight years of experience Open
Background Maternal cardiac disease is the most common cause of indirect maternal death, and women with pre‐existing cardiac disease have complex medical, obstetric and anaesthetic requirements. Our hospital commenced a multidisciplinary p…
View article: The Receptor for Advanced Glycation End Products (RAGE) Is Associated with Persistent Atrial Fibrillation
The Receptor for Advanced Glycation End Products (RAGE) Is Associated with Persistent Atrial Fibrillation Open
Soluble RAGE is elevated in Caucasian patients with AF, and both sRAGE and esRAGE predict the presence of persistent AF.