Ioan Tiberiu Nanea
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View article: Morphological and clinical aspects of acute postmyocardial remodeling in patients with pre-existing hypertrophy
Morphological and clinical aspects of acute postmyocardial remodeling in patients with pre-existing hypertrophy Open
Introduction: Cardiac remodeling is a relevant and unfavorable evolution of myocardial infarction, which is associated with an increased risk of progression to overt heart failure (HF). It is currently acknowledged as a fundamental therape…
View article: The real-world anti-inflammatory effect of SGLT2i in patients with chronic heart failure
The real-world anti-inflammatory effect of SGLT2i in patients with chronic heart failure Open
Inflammation plays a major role in the etiology of chronic heart failure and in inducing the progression to end-stage heart failure. This chronic inflammation, which accompanies heart failure, is not only local but also systemic and is usu…
View article: DIFFERENCES IN AUTONOMIC NERVOUS IMBALANCE ACROSS THE SPECTRUM OF HEART FAILURE THROUGH ECG HOLTER POWER SPECTRAL ANALYSIS
DIFFERENCES IN AUTONOMIC NERVOUS IMBALANCE ACROSS THE SPECTRUM OF HEART FAILURE THROUGH ECG HOLTER POWER SPECTRAL ANALYSIS Open
Divergences dans le déséquilibre du système nerveux autonome à travers le spectre de l'insuffisance cardiaque par l'analyse spectrale de puissance au Holter ECG Introduction.L'insuffisance cardiaque est un état complexe qui entraîne une ha…
View article: Evaluation of Autonomic Nervous System Through Spectral Analysis in Patients with Ischemic Heart Failure: A Systematic Review
Evaluation of Autonomic Nervous System Through Spectral Analysis in Patients with Ischemic Heart Failure: A Systematic Review Open
Heart failure is one of the most complex pathologies and most prevalent diseases, with around 64 million people affected globally (2% of the total adult population). In the initial phase of heart failure, studies have shown that the autono…
View article: Inflammation in Heart Failure—Future Perspectives
Inflammation in Heart Failure—Future Perspectives Open
Chronic heart failure is a terminal point of a vast majority of cardiac or extracardiac causes affecting around 1–2% of the global population and more than 10% of the people above the age of 65. Inflammation is persistently associated with…
View article: Left Ventricular Non-compaction Cardiomyopathy and Polycystic Kidney Disease Revealed by Inappropriate Polycythemia: A Fortuitous Association? Case Report
Left Ventricular Non-compaction Cardiomyopathy and Polycystic Kidney Disease Revealed by Inappropriate Polycythemia: A Fortuitous Association? Case Report Open
We present the case of a patient with heart failure with reduced left ventricular (LV) ejection fraction, diagnosed in the first instance by echocardiography and further on by more accurate cardiac magnetic resonance imaging with LV non-co…
View article: Androgen Deprivation Therapy, Hypogonadism and Cardiovascular Toxicity in Men with Advanced Prostate Cancer
Androgen Deprivation Therapy, Hypogonadism and Cardiovascular Toxicity in Men with Advanced Prostate Cancer Open
Androgen deprivation therapy (ADT) is successfully used in patients with advanced prostatic cancer, but there are many concerns about its systemic side effects, especially due to advanced age and frequent comorbidities in most patients. In…
View article: Exercise-Induced NT-pro BNP Secretion in Hypertensive Patients Without Heart Failure Can Diagnose the Subclinical Left Ventricle Dysfunction
Exercise-Induced NT-pro BNP Secretion in Hypertensive Patients Without Heart Failure Can Diagnose the Subclinical Left Ventricle Dysfunction Open
Hypertension is one of the main risk factors for developing left ventricle failure. The study was conducted at outpatient Clinic – Medlife, Memorial Hospital. It was an observational study. We analyzed the exercise-induced secretion of NT-…
View article: Subclinical left ventricular dysfunction in men under androgen deprivation therapy for prostate cancer, revealed by speckle‐tracking‐derived parameters, repolarization, and myocardial injury markers
Subclinical left ventricular dysfunction in men under androgen deprivation therapy for prostate cancer, revealed by speckle‐tracking‐derived parameters, repolarization, and myocardial injury markers Open
Objective To analyze global left ventricular longitudinal strain (GLS), mechanical dispersion (MD), electrocardiographic repolarization, and myocardial injury markers changes during androgen deprivation therapy (ADT) and subsequent hypogon…
View article: Speckle-tracking derived parameters of left ventricular function, repolarization and myocardial injury markers during androgen deprivation therapy
Speckle-tracking derived parameters of left ventricular function, repolarization and myocardial injury markers during androgen deprivation therapy Open
Background. Androgen deprivation therapy (ADT) and subsequent hypogonadism in patients with prostate cancer may cause cardiac toxicity. We aimed to analyse left ventricular longitudinal strain, mechanical dispersion, electrocardiographic r…
View article: Ventricular Remodeling in Aortic Sclerosis
Ventricular Remodeling in Aortic Sclerosis Open
Background and aims . Aortic sclerosis associates an increased risk of cardiovascular morbidity and mortality. Recent studies suggest that aortic sclerosis is able to produce ventricular remodeling through inflammatory, non-hemodynamic mec…
View article: Echocardiography in Patients with Atrial Fibrillation - What Should the Internist Doctor Know?
Echocardiography in Patients with Atrial Fibrillation - What Should the Internist Doctor Know? Open
Atrial fibrillation (AF) is the most common cardiac arrhythmia, with an increasing prevalence and an enormous clinical impact due to the high stroke rate, left ventricular dysfunction and excess mortality. The occurrence and maintenance of…
View article: Evolution of Electrocardiographic Repolarization Parameters During Antiandrogen Therapy in Patients with Prostate Cancer and Hypogonadism
Evolution of Electrocardiographic Repolarization Parameters During Antiandrogen Therapy in Patients with Prostate Cancer and Hypogonadism Open
We assessed the effects of antiandrogen therapy on ECG parameters of ventricular repolarization related to arrhythmic risk in 35 patients aged 70.3 ± 7 years with advanced prostate cancer treated with degarelix associated with enzalutamide…
View article: Electrocardiographic parameters of repolarization and heart rate variability in prostate cancer patients with drug induced hypogonadism
Electrocardiographic parameters of repolarization and heart rate variability in prostate cancer patients with drug induced hypogonadism Open
We aimed to assess the electrocardiographic changes related to arrhythmic risk in advanced prostate cancer patients with drug induced hypogonadism. The dataset contains raw clinical and ECG data from 35 patients treated with degarelix plus…
View article: The Significance of Ventricular Interdependence in Patients with Right Ventricular Hypertrophy and Normal Left Ventricular Function
The Significance of Ventricular Interdependence in Patients with Right Ventricular Hypertrophy and Normal Left Ventricular Function Open
The aim of the study is to quantify ventricular interactions by comparing tissue and spectral systolic echocardiographic parameters to allow the early identification of ventricular dysfunction. Clinical, paraclinical, electrocardiographic …
View article: The Significance of Ventricular Interdependence in Patients with Right Ventricular Hypertrophy and Normal Left Ventricular Function
The Significance of Ventricular Interdependence in Patients with Right Ventricular Hypertrophy and Normal Left Ventricular Function Open
The aim of the study is to quantify ventricular interactions by comparing tissue and spectral systolic echocardiographic parameters to allow the early identification of ventricular dysfunction. Clinical, paraclinical, electrocardiographic …
View article: Diagnostic Pitfalls in a Man with Systemic Lupus Erythematous
Diagnostic Pitfalls in a Man with Systemic Lupus Erythematous Open
VDRL positive reaction as a diagnostic tool for syphilis must be confirmed by other tests like TPHA and Western Blot reaction, especially in the absence of a clinical context, taking into account the possibility of false positive results.S…
View article: Transtoracical Ecocardiographic Assessment of Severe Degenerative Aortic Stenosis with Normal Ejection Fraction and Low Transvalvular Gradient
Transtoracical Ecocardiographic Assessment of Severe Degenerative Aortic Stenosis with Normal Ejection Fraction and Low Transvalvular Gradient Open
Purpose of the study: echocardiographic evaluation of the form of degenerative aortic stenosis (DAS) with preserved ejection fraction (EF) and low transvalvular gradient, in order to formulate the indication of valvular prosthesis as early…
View article: Atrial Strain in Atrial Fibrillation Patients: A 2D Speckle Tracking Echocardiography Study
Atrial Strain in Atrial Fibrillation Patients: A 2D Speckle Tracking Echocardiography Study Open
Objectives . In this study we tried to determine the values of the left atrial (LA) strain in patients with atrial fibrillation (AF) and set a parameter that could be a predictor of sinus rhythm (SR) maintenance. Study population. We inclu…
View article: Complex Etiology in a Case of Pulmonary Hypertension
Complex Etiology in a Case of Pulmonary Hypertension Open
Porto-pulmonary hypertension (PPH) is the association between portal hypertension (PoH) due to liver disease or extra hepatic etiology and pulmonary hypertension (PH). It’s prevalence ranges between 2 and 16 % (1,2) and it’s diagnosis requ…
View article: The Influence of Diabetes Mellitus on Sodium Homeostasis in Patients with Preserved Ejection Fraction Heart Failure
The Influence of Diabetes Mellitus on Sodium Homeostasis in Patients with Preserved Ejection Fraction Heart Failure Open
The objective of the study was to analyze the characteristics of the patients with preserved ejection fraction heart failure (HfpEF) who develop hyponatremia, in relationship with the diabetes mellitus (DM). The current study is an observa…
View article: Particular etiology in a case of peripheral tetraparesis
Particular etiology in a case of peripheral tetraparesis Open
Key Clinical Message Lead intoxication is a rare but potentially fatal disease without appropriate intervention. The diagnosis is often difficult because of various organs involvement. We report the case of nonprofessional lead intoxicatio…
View article: Electrocardiographic measures of repolarization dispersion and their relationships with echocardiographic indices of ventricular remodeling and premature ventricular beats in hypertension.
Electrocardiographic measures of repolarization dispersion and their relationships with echocardiographic indices of ventricular remodeling and premature ventricular beats in hypertension. Open
The repolarization parameters Tpe interval and Tpe/QT ratio correlate with LVMI and indices of left ventricular diastolic function and show better predictive values than traditional parameters such as QT interval and QT dispersion. Lead V3…
View article: P1790The relationship between intraplatelet oxidative stress and platelet aggregation in patients with stable coronary artery disease
P1790The relationship between intraplatelet oxidative stress and platelet aggregation in patients with stable coronary artery disease Open
398 Coronary artery disease: from bench to bedside dence of microchannels (80.1% vs. 20.9%,P=0.002), TCFA (76.3% vs. 30.2%,P=0.014) and macrophages (83.6% vs. 60.6%,P=0.037) was significantly higher in the high level group.Conclusions: The…