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View article: How Electrical Storms Recur Over Time in Patients With Implantable Cardioverter Defibrillators ― Subanalysis of the Nippon Storm Study ―
How Electrical Storms Recur Over Time in Patients With Implantable Cardioverter Defibrillators ― Subanalysis of the Nippon Storm Study ― Open
E-storm recurrences may have a negative impact on prognosis. Once patients with primary prevention experience an E-storm episode, they face a similar risk of subsequent recurrent E-storms as patients with secondary prevention.
View article: Heparin-induced thrombocytopenia requiring VA-ECMO management during percutaneous coronary intervention for acute coronary syndrome: A case report
Heparin-induced thrombocytopenia requiring VA-ECMO management during percutaneous coronary intervention for acute coronary syndrome: A case report Open
View article: Two-Year Outcomes of Primary Prophylactic Use of Defibrillators for Ischemic and Non-Ischemic Cardiomyopathy ― Propensity Score-Matched Analysis From the Nippon Storm Study ―
Two-Year Outcomes of Primary Prophylactic Use of Defibrillators for Ischemic and Non-Ischemic Cardiomyopathy ― Propensity Score-Matched Analysis From the Nippon Storm Study ― Open
This subanalysis of propensity score-matched patients from the Nippon Storm Study revealed that the risk of appropriate ICD therapy was significantly higher in patients with NICM than in those with ICM.
View article: Two-year outcomes of primary prophylactic use of defibrillators with ischemic and non-ischemic cardiomyopathy: propensity score-matched analysis from NIPPON STORM Study
Two-year outcomes of primary prophylactic use of defibrillators with ischemic and non-ischemic cardiomyopathy: propensity score-matched analysis from NIPPON STORM Study Open
Background In 2016, the DANISH study showed negative results regarding the efficacy of implantable cardioverter defibrillators (ICDs) for patients with non-ischemic cardiomyopathy (NICM) and reduced left ventricular ejection fraction (LVEF…
View article: Effectiveness of Implantable Cardioverter Defibrillator in Patients With Non-Ischemic Heart Failure With Systolic Dysfunction ― Subanalysis of the Nippon Storm Study ―
Effectiveness of Implantable Cardioverter Defibrillator in Patients With Non-Ischemic Heart Failure With Systolic Dysfunction ― Subanalysis of the Nippon Storm Study ― Open
In propensity score-matched Japanese NIHF patients, the incidence of appropriate ICD therapy and ES was significantly higher in SP than PP patients. Impaired renal function in SP patients and anemia in PP patients increased the likelihood …
View article: High platelet reactivity is a predictor of left ventricular remodelling in patients with acute myocardial infarction
High platelet reactivity is a predictor of left ventricular remodelling in patients with acute myocardial infarction Open
Aims Acute myocardial infarction (AMI) is associated with left ventricular remodelling (LVR), which leads to progressive heart failure. Platelets play a pivotal role in promoting systemic and cardiac inflammatory responses during the compl…
View article: JCS/JHRS 2021 guideline focused update on non‐pharmacotherapy of cardiac arrhythmias
JCS/JHRS 2021 guideline focused update on non‐pharmacotherapy of cardiac arrhythmias Open
View article: JCS/JHRS 2021 Guideline Focused Update on Non-Pharmacotherapy of Cardiac Arrhythmias
JCS/JHRS 2021 Guideline Focused Update on Non-Pharmacotherapy of Cardiac Arrhythmias Open
View article: Electrical Storm as an Independent Mortality Risk in Patients with Preserved or Moderately Reduced Left Ventricular Function
Electrical Storm as an Independent Mortality Risk in Patients with Preserved or Moderately Reduced Left Ventricular Function Open
Electrical storm (ES), defined by 3 or more occurrences of ventricular arrhythmias within 24 hours, has been shown to be associated with an increased risk of mortality; however, detailed information remains lacking. We aimed to examine the…
View article: Cardio-ankle vascular index is useful screening method to detect obstructive coronary artery disease in asymptomatic diabetes patients with subclinical atherosclerosis
Cardio-ankle vascular index is useful screening method to detect obstructive coronary artery disease in asymptomatic diabetes patients with subclinical atherosclerosis Open
Background Patients with diabetes mellitus are at very high risk for obstructive coronary artery disease; however, invasive coronary angiography is not allowed to apply in all patients. Cardio-ankle vascular index (CAVI), a marker of arter…
View article: CORRIGENDUM: JCS/JHRS 2019 Guideline on Non-Pharmacotherapy of Cardiac Arrhythmias
CORRIGENDUM: JCS/JHRS 2019 Guideline on Non-Pharmacotherapy of Cardiac Arrhythmias Open
View article: Anti‐tachycardia pacing for non‐fast and fast ventricular tachycardias in individual Japanese patients: From Nippon‐storm study
Anti‐tachycardia pacing for non‐fast and fast ventricular tachycardias in individual Japanese patients: From Nippon‐storm study Open
Background Anti‐tachycardia pacing (ATP) delivered from an implantable device is a useful tool to terminate ventricular tachycardia (VT). But its real‐world efficacy for those patients having multiple VTs with varying VT rates has not been…
View article: JCS/JHRS 2019 guideline on non‐pharmacotherapy of cardiac arrhythmias
JCS/JHRS 2019 guideline on non‐pharmacotherapy of cardiac arrhythmias Open
The original guideline for non-pharmacological treatments (cardiac implantable electronic device, catheter ablation, and arrhythmia surgery) of arrhythmias (Japanese Circulation Society [JCS] Guideline on Non-pharmacotherapy of Cardiac Arr…
View article: JCS/JHRS 2019 Guideline on Non-Pharmacotherapy of Cardiac Arrhythmias
JCS/JHRS 2019 Guideline on Non-Pharmacotherapy of Cardiac Arrhythmias Open
1 Current status of non‐pharmacotherapies in Japan
Pacemaker treatment for bradyarrhythmia was first approved for national health insurance coverage in Japan in 1974, and its use rapidly became widespread thereafter. Approximately 40 year…
View article: Risk factors for the first and second inappropriate implantable cardioverter-defibrillator therapy
Risk factors for the first and second inappropriate implantable cardioverter-defibrillator therapy Open
View article: Comparison of 2-year outcomes between primary and secondary prophylactic use of defibrillators in patients with coronary artery disease: A prospective propensity score–matched analysis from the Nippon Storm Study
Comparison of 2-year outcomes between primary and secondary prophylactic use of defibrillators in patients with coronary artery disease: A prospective propensity score–matched analysis from the Nippon Storm Study Open
View article: Comparison of second appropriate defibrillator therapy occurrence in patients implanted for primary prevention and secondary prevention – Sub-analysis of the Nippon Storm Study-
Comparison of second appropriate defibrillator therapy occurrence in patients implanted for primary prevention and secondary prevention – Sub-analysis of the Nippon Storm Study- Open
View article: Systematic Evaluation of <i>KCNQ1</i> Variant Using ACMG/AMP Guidelines and Risk Stratification in Long QT Syndrome Type 1
Systematic Evaluation of <i>KCNQ1</i> Variant Using ACMG/AMP Guidelines and Risk Stratification in Long QT Syndrome Type 1 Open
Background - Mutation/variant-site specific risk stratification in long-QT syndrome type 1 (LQT1) has been well investigated, but it is still challenging to adapt current enormous genomic information to clinical aspects caused by each muta…
View article: Successful Nonsurgical Treatment of Acute Peritonitis Caused by a Large Thrombosis of the Superior Mesenteric Vein in a 25-year-old Woman
Successful Nonsurgical Treatment of Acute Peritonitis Caused by a Large Thrombosis of the Superior Mesenteric Vein in a 25-year-old Woman Open
Superior mesenteric venous thrombosis (SMVT), which results from various etiologies, including coagulation disorders, can be diagnosed early using advanced imaging technology. However, few reports have described the nonsurgical treatment o…
View article: JCS 2016 Guideline on Diagnosis and Treatment of Cardiac Sarcoidosis ― Digest Version ―
JCS 2016 Guideline on Diagnosis and Treatment of Cardiac Sarcoidosis ― Digest Version ― Open
View article: Association of Genetic and Clinical Aspects of Congenital Long QT Syndrome With Life-Threatening Arrhythmias in Japanese Patients
Association of Genetic and Clinical Aspects of Congenital Long QT Syndrome With Life-Threatening Arrhythmias in Japanese Patients Open
In this retrospective analysis, pathogenic variants in the pore areas of the channels were associated with higher risk of arrhythmic events than were other variants in each genotype, while sex-associated differences were observed in patien…
View article: Association between changes in platelet reactivity during elective percutaneous coronary intervention and periprocedural myocardial infarction: A pilot study
Association between changes in platelet reactivity during elective percutaneous coronary intervention and periprocedural myocardial infarction: A pilot study Open
View article: Genotype-Phenotype Correlation of <i>SCN5A</i> Mutation for the Clinical and Electrocardiographic Characteristics of Probands With Brugada Syndrome
Genotype-Phenotype Correlation of <i>SCN5A</i> Mutation for the Clinical and Electrocardiographic Characteristics of Probands With Brugada Syndrome Open
Background: The genotype-phenotype correlation of SCN5A mutations as a predictor of cardiac events in Brugada syndrome remains controversial. We aimed to establish a registry limited to probands, with a long follow-up period, so that the g…
View article: Local Left Ventricular Epicardial J Waves and Late Potentials in Brugada Syndrome Patients with Inferolateral Early Repolarization Pattern
Local Left Ventricular Epicardial J Waves and Late Potentials in Brugada Syndrome Patients with Inferolateral Early Repolarization Pattern Open
Background: Brugada syndrome (BrS) is characterized by J-point or ST-segment elevation on electrocardiograms (ECGs) and increased risk of ventricular fibrillation (VF). In BrS, epicardial depolarization abnormality with delayed pote…
View article: Guidelines for Therapeutic Drug Monitoring of Cardiovascular Drugs Clinical Use of Blood Drug Concentration Monitoring (JCS 2015) ― Digest Version ―
Guidelines for Therapeutic Drug Monitoring of Cardiovascular Drugs Clinical Use of Blood Drug Concentration Monitoring (JCS 2015) ― Digest Version ― Open
CQ2 Does blood drug concentration monitoring of antiarrhythmic drugs help reduce ADRs in patients with arrhythmia who are receiving antiarrhythmic drugs?.............. 588 CQ3 Can we shorten the time to achieve an optimal dosage regimen by…
View article: HotBalloon Ablation of the Pulmonary Veins for Paroxysmal AF
HotBalloon Ablation of the Pulmonary Veins for Paroxysmal AF Open
This study demonstrates the superiority of HBA compared with ADT for treatment of patients with PAF, and a favorable safety profile.
View article: Activation Pattern of the Polymorphic Ventricular Tachycardia and Ventricular Fibrillation on Body Surface Mapping in Patients With Brugada Syndrome
Activation Pattern of the Polymorphic Ventricular Tachycardia and Ventricular Fibrillation on Body Surface Mapping in Patients With Brugada Syndrome Open
Clinical and experimental studies have shown the existence of an arrhythmogenic substrate in the right ventricular outflow tract (RVOT) in patients with Brugada syndrome (BrS). To evaluate the importance of the RVOT, we evaluated the activ…
View article: Enhancement of Spontaneous Activity by HCN4 Overexpression in Mouse Embryonic Stem Cell-Derived Cardiomyocytes - A Possible Biological Pacemaker
Enhancement of Spontaneous Activity by HCN4 Overexpression in Mouse Embryonic Stem Cell-Derived Cardiomyocytes - A Possible Biological Pacemaker Open
We generated HCN4-overexpresssing mESC-CMs expressing genes required for impulse conduction, showing rapid spontaneous beating, responding to an If inhibitor and beta-adrenergic receptor agonist, and having pacing ability in an in vitro co…
View article: Incidence and Clinical Significance of Brugada Syndrome Masked by Complete Right Bundle-Branch Block
Incidence and Clinical Significance of Brugada Syndrome Masked by Complete Right Bundle-Branch Block Open
In a small BrS population, CRBBB can completely mask typical BrS-type ECG. BrS masked by CRBBB is associated with the same risk of fatal ventricular tachyarrhythmia as other BrS.