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View article: Interaction between benign prostatic hyperplasia/prostate size and incidence of prostate cancer: A scoping review and update for practicing urologists
Interaction between benign prostatic hyperplasia/prostate size and incidence of prostate cancer: A scoping review and update for practicing urologists Open
Numerous clinical studies have demonstrated a negative (invert) association between benign prostatic hyperplasia/prostate size and the incidence of prostate cancer (PCa). This scoping review presents published clinical studies on the assoc…
View article: Post hoc analysis of the finasteride effect on the incidence of prostate cancer stratified by prostate gland volume in the Prostate Cancer Prevention Trials (PCPT)
Post hoc analysis of the finasteride effect on the incidence of prostate cancer stratified by prostate gland volume in the Prostate Cancer Prevention Trials (PCPT) Open
Purpose: Studies have shown that finasteride may decrease the incidence of prostate cancer (PCa) in general but may increase the incidence of high-grade PCa. There have been conflicting hypotheses attempting to explain this phenomenon. Thi…
View article: The author’s reply
The author’s reply Open
View article: Current Clinical Aspects of Androgen Deprivation Therapy for Locally Advanced and Metastatic Prostate Cancer: A Scoping Review for Urologists and Medical Providers
Current Clinical Aspects of Androgen Deprivation Therapy for Locally Advanced and Metastatic Prostate Cancer: A Scoping Review for Urologists and Medical Providers Open
Prostate cancer (PCa) currently stands as the most common malignancy and the second most common cause of death in men worldwide. Dr. C. Huggins revolutionized the field of PCa treatment through his work investigating the therapeutic effect…
View article: Complete Growth Inhibition of Pseudomonas aeruginosa by Organo-Selenium-Incorporated Urinary Catheter Material
Complete Growth Inhibition of Pseudomonas aeruginosa by Organo-Selenium-Incorporated Urinary Catheter Material Open
To further investigate the inhibition of Pseudomonas aeruginosa’s in vitro growth and biofilm formation by an organo-selenium-incorporated polyurethane (PU) catheter material. P. aeruginosa, Staphylococcus aureus, and Candida albicans were…
View article: Computerized metric assessment of glandular tissue volume within the peripheral zone of the prostate using combined magnetic resonance imaging and histopathology: Possible pathophysiological implications on prostate cancer development
Computerized metric assessment of glandular tissue volume within the peripheral zone of the prostate using combined magnetic resonance imaging and histopathology: Possible pathophysiological implications on prostate cancer development Open
The combination of MRI and histopathology offers a novel approach for precise quantification of glandular tissue within the prostatic PZ. This study corroborates the hypothesis of PZ compression via an enlarging transition zone in larger B…
View article: The Origin of BPH and Prostate Cancer in Different Prostate Zones and the Impact on the Incidence of Prostate Cancer: A Systematic Review and Update of the Literature for Urologists and Clinicians
The Origin of BPH and Prostate Cancer in Different Prostate Zones and the Impact on the Incidence of Prostate Cancer: A Systematic Review and Update of the Literature for Urologists and Clinicians Open
Background and objectivesNumerous clinical studies over recent years have reported an inverse relationship between benign prostatic hyperplasia (BPH) size and the incidence of prostate cancer (PCa), leading to the clinical hypothesis that …
View article: Potential Patient Bias by Insurance Coverage on CG-CAHPS Surveys: Impact on Physician Reimbursement
Potential Patient Bias by Insurance Coverage on CG-CAHPS Surveys: Impact on Physician Reimbursement Open
Objectives: Investigate the relationship between payor type and patient experience scores. Design: Cross-sectional retrospective study. Setting: Academic orthopaedic outpatient clinic. Patients: All patients seen in our clinic were given a…
View article: Association Between Prostate Size and MRI Determined Quantitative Prostate Zonal Measurements
Association Between Prostate Size and MRI Determined Quantitative Prostate Zonal Measurements Open
The data revealed that PZT was significantly smaller in the subgroup of patients with higher TPV. This supports the hypothesis of PZ compression and thinning caused by the growing and expanding TZ in BPH prostates. This dynamic growth-rela…
View article: Evolving Hypothesis that Prostate/BPH Size Matters in Protection against Prostate Cancer
Evolving Hypothesis that Prostate/BPH Size Matters in Protection against Prostate Cancer Open
Benign prostatic hyperplasia (BPH) and prostate cancer (PCa) are the two predominant urologic diseases affecting aging men. As a matter of fact, 95–98% of elderly men with prostate as their “primary organ disease” for consulting urologists…
View article: Evolution of Androgen Deprivation Therapy (ADT) and Its New Emerging Modalities in Prostate Cancer: An Update for Practicing Urologists, Clinicians and Medical Providers
Evolution of Androgen Deprivation Therapy (ADT) and Its New Emerging Modalities in Prostate Cancer: An Update for Practicing Urologists, Clinicians and Medical Providers Open
Erin Choi, John Buie, Jaime Camacho, Pranav Sharma, Werner TW de Riese Department of Urology, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, USACorrespondence: Werner TW de Riese, Department of Urology, Scho…
View article: Any Correlation Between Prostate Volume and Incidence of Prostate Cancer: A Review of Reported Data for the Last Thirty Years
Any Correlation Between Prostate Volume and Incidence of Prostate Cancer: A Review of Reported Data for the Last Thirty Years Open
To our knowledge, this is the first systematic review on the important clinical question of interaction between prostate size and the incidence of PCa. The results are demonstrating an inverse relationship, and therefore reveal strong evid…
View article: Quantitative measurements of prostatic zones by MRI and their dependence on prostate size: possible clinical implications in prostate cancer
Quantitative measurements of prostatic zones by MRI and their dependence on prostate size: possible clinical implications in prostate cancer Open
Aim: Many studies support an inverse relationship between benign prostate hypertrophy (BPH) size and incidence of prostate cancer (PCa), but the causal link between these conditions is poorly understood. Recent studies suggest that a growi…
View article: Possible clinical implications of prostate capsule thickness and glandular epithelial cell density in benign prostate hyperplasia
Possible clinical implications of prostate capsule thickness and glandular epithelial cell density in benign prostate hyperplasia Open
The results suggest that growth of the transition zone in BPH causes increased fibrosis of the PZ, leading to atrophy and fibrosis of glandular cells. As 80% of PCa originates from the glandular epithelium within the PZ, this observed phen…
View article: <p>New Implantable Tibial Nerve Stimulation Devices: Review of Published Clinical Results in Comparison to Established Neuromodulation Devices</p>
New Implantable Tibial Nerve Stimulation Devices: Review of Published Clinical Results in Comparison to Established Neuromodulation Devices Open
Practicing urologists should be aware of this new treatment option when counseling their patients regarding treatment for OAB.
View article: <p>Histological changes of the peripheral zone in small and large prostates and possible clinical implications</p>
Histological changes of the peripheral zone in small and large prostates and possible clinical implications Open
The results demonstrate that prostate hypertrophy leads to both decreased gland density in the peripheral zone and increased capsule thickness, suggesting that growth-induced expansion of the prostate against its capsule leads to compressi…
View article: Smaller Prostate Volume is Associated with Adverse Pathological Features and Biochemical Recurrence after Radical Prostatectomy
Smaller Prostate Volume is Associated with Adverse Pathological Features and Biochemical Recurrence after Radical Prostatectomy Open
Introduction: The relationship between prostate cancer (PCa) and benign prostatic hyperplasia is unclear. Reduction in androgenicity and lower intraprostatic growth factor concentrations in smaller prostates may serve a more ideal environm…
View article: Occlusion of bilateral dorsal penile arteries resulting in glans necrosis in an obese male truck driver
Occlusion of bilateral dorsal penile arteries resulting in glans necrosis in an obese male truck driver Open
Ischemic penile gangrene is an uncommon urologic condition associated with significant morbidity. Etiology of the disease is due to vasculogenic ischemia of the penile tissue. Presented are a series of images from a case of a 51-year-old m…
View article: PEDF increases the tumoricidal activity of macrophages towards prostate cancer cells in vitro
PEDF increases the tumoricidal activity of macrophages towards prostate cancer cells in vitro Open
These data established that modulating the molecular interactions between macrophages and PCa cells using PEDF may be a promising strategy for PCa treatment.
View article: Rare Occurrence of a Poorly Differentiated Neuroendocrine Tumor of the Bladder
Rare Occurrence of a Poorly Differentiated Neuroendocrine Tumor of the Bladder Open
Neuroendocrine tumors rarely occur in the urinary bladder. They can be carcinomatous, subdivided into small cell and large cell pathology. Small cell carcinoma of the bladder is a rarity that may present at an advanced pathologic stage. No…
View article: Association of prostate volume with incidence and aggressiveness of prostate cancer
Association of prostate volume with incidence and aggressiveness of prostate cancer Open
Shadi Al-Khalil, Christine Ibilibor, James Thomas Cammack, Werner de Riese Department of Urology, Texas Tech University Health Sciences Center, Lubbock, TX, USA Objective: The aim of this study was to investigate the possible correlation b…
View article: The Association between Autosomal Dominant Polycystic Kidney Disease and Renal Cell Carcinoma
The Association between Autosomal Dominant Polycystic Kidney Disease and Renal Cell Carcinoma Open
Objectives: The relationship between autosomal dominant polycystic kidney disease (ADPKD) and renal cell carcinoma (RCC) is investigated to determine a link that would guide management due to elevated RCC risk. Current literature is inconc…