Tian Xia
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View article: Cost-effectiveness analysis of cabozantinib plus atezolizumab for advanced hepatocellular carcinoma
Cost-effectiveness analysis of cabozantinib plus atezolizumab for advanced hepatocellular carcinoma Open
Background Cabozantinib combined with atezolizumab has been shown to prolong progression-free survival in first-line treatment of advanced hepatocellular carcinoma (HCC). However, the cost-effectiveness of this regimen remains unknown. Thi…
View article: Segmentor-Guided Counterfactual Fine-Tuning for Locally Coherent and Targeted Image Synthesis
Segmentor-Guided Counterfactual Fine-Tuning for Locally Coherent and Targeted Image Synthesis Open
Counterfactual image generation is a powerful tool for augmenting training data, de-biasing datasets, and modeling disease. Current approaches rely on external classifiers or regressors to increase the effectiveness of subject-level interv…
View article: Relationship Between Type 1 Diabetes Mellitus and Dental Caries Status with Related Oral Health Indicators in Children
Relationship Between Type 1 Diabetes Mellitus and Dental Caries Status with Related Oral Health Indicators in Children Open
Type 1 diabetes mellitus may alter saliva composition, while hyperglycemia can cause gingival inflammation and affect periodontal health. These changes may interfere with tooth mineralization, increasing caries risk in children.
View article: Risk factors of early subsidence of 3D-printed artificial vertebral body following single-level anterior cervical corpectomy and fusion (ACCF): retrospective study of 98 patients
Risk factors of early subsidence of 3D-printed artificial vertebral body following single-level anterior cervical corpectomy and fusion (ACCF): retrospective study of 98 patients Open
Increased age, segmental slope, intraoperative retraction height, and a lower implant sagittal size ratio are significant risk factors for AVB subsidence. Surgeons should consider these factors in surgery planning and avoid excessive intra…
View article: Robust image representations with counterfactual contrastive learning
Robust image representations with counterfactual contrastive learning Open
Contrastive pretraining can substantially increase model generalisation and downstream performance. However, the quality of the learned representations is highly dependent on the data augmentation strategy applied to generate positive pair…
View article: Technical success, clinical efficacy, and safety of endoscopic minor papilla interventions for symptomatic pancreatic diseases
Technical success, clinical efficacy, and safety of endoscopic minor papilla interventions for symptomatic pancreatic diseases Open
BACKGROUND Endoscopic minor papilla intervention (EMPI) is an option for diagnosing or treating symptomatic pancreatic diseases in cases with failed pancreatic duct deep cannulation via the major papilla, pancreas divisum with obstruction …
View article: An assisted suspension fixation technique in transperitoneal laparoscopic pyeloplasty for infants and young children with ureteropelvic junction obstruction: a retrospective cohort study
An assisted suspension fixation technique in transperitoneal laparoscopic pyeloplasty for infants and young children with ureteropelvic junction obstruction: a retrospective cohort study Open
The use of assisted suspension fixation in transperitoneal LDP is safe and efficient for infants and young children, helping to reduce operative time, overcome the small laparoscopic operating area, and address the steep learning curve, ma…
View article: Policy research on role of traditional medicine in emergency health system construction based on the PMC index model: evidence from China
Policy research on role of traditional medicine in emergency health system construction based on the PMC index model: evidence from China Open
Background The integration of traditional Chinese medicine (TCM) into emergency health systems in China serves as a model for global policy development and refining the inclusion of traditional medicine in health emergencies. Methods This …
View article: RAPO: An Automated Performance Optimization Tool for Redis Clusters in Distributed Storage Metadata Management
RAPO: An Automated Performance Optimization Tool for Redis Clusters in Distributed Storage Metadata Management Open
Distributed storage systems are well-equipped to address the demands of massive data storage and rapid access in the era of big data. However, as the scale of these systems continues to expand, challenges related to data localization, perf…
View article: Transumbilical single-site double-port laparoscopic appendectomy in children. Report of a single center experience with comparison with three-port laparoscopic appendectomy.
Transumbilical single-site double-port laparoscopic appendectomy in children. Report of a single center experience with comparison with three-port laparoscopic appendectomy. Open
TSSDPLA is a reliable technical technique for the management of acute appendicitis. This approach offers several advantages, including improved cosmetic outcomes, reduced surgical trauma, and lower costs.
View article: Enhanced re‐processability of poly (butylene adipate‐co‐terephthalate) ( <scp>PBAT</scp> ) via chain extension toward a more sustainable end‐of‐life
Enhanced re‐processability of poly (butylene adipate‐co‐terephthalate) ( <span>PBAT</span> ) via chain extension toward a more sustainable end‐of‐life Open
Poly (butylene adipate‐co‐terephthalate) (PBAT) is a biodegradable polymer recognized for its potential to reduce plastic waste due to its biodegradability and compostability. However, conventional end‐of‐life options for PBAT, such as com…
View article: The effectiveness and safety of computed tomography-guided hook-wire localization for secondary video-assisted thoracoscopic surgery: a retrospective study
The effectiveness and safety of computed tomography-guided hook-wire localization for secondary video-assisted thoracoscopic surgery: a retrospective study Open
CT-guided hook-wire localization can effectively complete the localization of isolated nodules on the ipsilateral or contralateral side in patients requiring a second pulmonary resection, with similar safety. In the future, it is more advi…
View article: Linoleic Acid Enhances Renal Tubular Epithelial Cells Autophagy Caused by Calcium Oxalate Monohydrate Crystals
Linoleic Acid Enhances Renal Tubular Epithelial Cells Autophagy Caused by Calcium Oxalate Monohydrate Crystals Open
High intake of dietary linoleic acid may increase the incidence of many diseases. The aim of this research is to examine the impact of linoleic acid on the damage caused by calcium oxalate kidney stones on renal tubular epithelial cells. C…
View article: Latent 3D Brain MRI Counterfactual
Latent 3D Brain MRI Counterfactual Open
The number of samples in structural brain MRI studies is often too small to properly train deep learning models. Generative models show promise in addressing this issue by effectively learning the data distribution and generating high-fide…
View article: From a Word to a World: An Innovative Teaching at a Higher Educational Institution in China
From a Word to a World: An Innovative Teaching at a Higher Educational Institution in China Open
China’s higher educational reform created innovative ways to cultivate talents urgently needed for social development during the late 1970s. This paper investigates an enlightening teaching reform of English major on the basis of Tianshui …
View article: Silencing Exosomal circ102927 Inhibits Foot Melanoma Metastasis via Regulating Invasiveness, Epithelial-Mesenchymal Transition and Apoptosis
Silencing Exosomal circ102927 Inhibits Foot Melanoma Metastasis via Regulating Invasiveness, Epithelial-Mesenchymal Transition and Apoptosis Open
Our investigation suggests that silencing exosomal circRNA102927 may suppress foot melanoma metastasis by inhibiting invasiveness, EMT and promoting apoptosis.
View article: Screening optimal DC-targeting peptide to enhance the immune efficacy of recombinant <i>Lactobacillus</i> expressing RHDV VP60
Screening optimal DC-targeting peptide to enhance the immune efficacy of recombinant <i>Lactobacillus</i> expressing RHDV VP60 Open
Dendritic cells (DCs) present an ideal target for delivering immunogenic cargo due to their potent antigen-presenting capabilities. This targeting approach holds promise in vaccine development by enhancing the efficiency of antigen recogni…
View article: Preparation of Nb5+ Doped Na3V2(PO4)3 Cathode Material for Sodium Ion Batteries
Preparation of Nb5+ Doped Na3V2(PO4)3 Cathode Material for Sodium Ion Batteries Open
Sodium-ion batteries (SIBs) have emerged as a promising alternative to lithium-ion batteries (LIBs) due to the abundance and low cost of sodium resources. Cathode material plays a crucial role in the performance of sodium ion batteries det…
View article: Current Research Status of Primary Closure after Laparoscopic Biliary Exploration
Current Research Status of Primary Closure after Laparoscopic Biliary Exploration Open
Choledocholithiasis is a biliary system disorder that plagues people's health. With the use and development of minimally invasive techniques, laparoscopy, duodenoscopy, and choledochoscopy, the treatment of choledocholithiasis has become m…
View article: Counterfactual contrastive learning: robust representations via causal image synthesis
Counterfactual contrastive learning: robust representations via causal image synthesis Open
Contrastive pretraining is well-known to improve downstream task performance and model generalisation, especially in limited label settings. However, it is sensitive to the choice of augmentation pipeline. Positive pairs should preserve se…
View article: Transumbilical single-site double-port laparoscopic appendectomy versus three-port laparoscopic appendectomy in children: a single center experience
Transumbilical single-site double-port laparoscopic appendectomy versus three-port laparoscopic appendectomy in children: a single center experience Open
Objective ：Transumbilical single-site double-port laparoscopic appendectomy (TSSDPLA) is a new and minimally invasive technique for the treatment of acute appendicitis. This study aimed to explore the clinical outcomes of TSSDPLA versus th…