Tabish Chawla
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View article: TP53 c.730G > A pathogenic variant as a plausible candidate biomarker in pancreatic ductal adenocarcinoma patients from Karachi, pakistan: a retrospective cohort study
TP53 c.730G > A pathogenic variant as a plausible candidate biomarker in pancreatic ductal adenocarcinoma patients from Karachi, pakistan: a retrospective cohort study Open
Background Pancreatic cancers is known to stand among the most aggressive cancers with low survival rate. Research indicates that investigating target biomarkers can provide scientific grounds for tailored treatments in cancers. However, b…
View article: Proteomic biomarkers profiling in Pakistani pancreatic ductal adenocarcinoma population: a retrospective cohort study
Proteomic biomarkers profiling in Pakistani pancreatic ductal adenocarcinoma population: a retrospective cohort study Open
Aim: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers. Research in various cancers suggests that investigating target biomarkers may provide directions to precision medicine. However, expression of biomarkers v…
View article: The frequency and associated factors of typhoid carriage in patients undergoing cholecystectomy for gallbladder disease in Pakistan: A cross-sectional study
The frequency and associated factors of typhoid carriage in patients undergoing cholecystectomy for gallbladder disease in Pakistan: A cross-sectional study Open
Background Enteric fever is caused by Salmonella enterica serovars Typhi ( S . Typhi) and Paratyphi A, B, and C. It continues to be a significant cause of morbidity and mortality worldwide. In highly endemic areas, children are disproporti…
View article: Significant Association of PD‐L1 With CD44 Expression and Patient Survival: Avenues for Immunotherapy and Cancer Stem Cells Downregulation in Pancreatic Cancers
Significant Association of PD‐L1 With CD44 Expression and Patient Survival: Avenues for Immunotherapy and Cancer Stem Cells Downregulation in Pancreatic Cancers Open
Background: Pancreatic cancers are known for their aggressive nature. This aggressiveness may be attributed to the presence of cancer stem cells (CSCs), which promote relapse, metastasis, and resistance to chemotherapy. Targeting CSCs is e…
View article: The frequency of typhoid carriage in patients undergoing cholecystectomy for gallbladder disease in Pakistan: A cross-sectional study
The frequency of typhoid carriage in patients undergoing cholecystectomy for gallbladder disease in Pakistan: A cross-sectional study Open
Background Enteric fever is caused by Salmonella enterica serovars Typhi ( S . Typhi) and Paratyphi A, B, and C. It continues to be a significant cause of morbidity and mortality worldwide. In highly endemic areas, children are disproporti…
View article: Acute presentation of cocoon abdomen as septic peritonitis mimicking with strangulated internal herniation: a case report
Acute presentation of cocoon abdomen as septic peritonitis mimicking with strangulated internal herniation: a case report Open
Background Abdominal cocoon syndrome is a rare cause of intestinal obstruction in which loops of small bowel get entrapped inside a fibro-collagenous membrane. Condition is also known in the literature as sclerosing peritonitis and in the …
View article: Post-operative pain after laparoscopic ventral hernia repair, the impact of mesh soakage with bupivacaine solution versus normal saline solution: A randomised controlled trial (HAPPIEST Trial)
Post-operative pain after laparoscopic ventral hernia repair, the impact of mesh soakage with bupivacaine solution versus normal saline solution: A randomised controlled trial (HAPPIEST Trial) Open
Trial was registered with clinicaltrials. gov (NCT03035617)URL: https://clinicaltrials. gov.
View article: Congenital Morgagni hernia presenting as complete small bowel obstruction in the adult - A case report
Congenital Morgagni hernia presenting as complete small bowel obstruction in the adult - A case report Open
CDH of Morgagni type can present uncommonly in adults with symptoms. A good history and clinical examination along with aid of chest x-ray and CT scan should establish the diagnosis. Early surgical intervention is key to prevent ischemia a…
View article: Risk Factors of Pancreatic Fistula in Distal Pancreatectomy Patients
Risk Factors of Pancreatic Fistula in Distal Pancreatectomy Patients Open
Introduction. Benign and malignant lesions of the pancreas located at the body and tail of the pancreas are managed by the standard procedure of distal pancreatectomy (DP). The mortality associated with this procedure is reported as less t…
View article: Perioperative hypothermia in colorectal surgeries: are we doing enough to prevent it?
Perioperative hypothermia in colorectal surgeries: are we doing enough to prevent it? Open
Perioperative incidence of hypothermia was found to be quite high despite appropriate measures. Factors responsible need to be explored and rectified.
View article: Thyroid dysfunction in pregnancy - a tertiary care centre experience
Thyroid dysfunction in pregnancy - a tertiary care centre experience Open
Introduction: Thyroid dysfunction has profound effect on both the mother and the fetus. This study was conducted in order to evaluate the thyroid function in pregnancy and its association with adverse maternal and fetal outcome. Method: …
View article: Male Breast Cancer: a 24 Year Experience of a Tertiary Care Hospital in Pakistan
Male Breast Cancer: a 24 Year Experience of a Tertiary Care Hospital in Pakistan Open
Male breast cancer may be on a slow rise but is still an uncommon disease. Tumor stage and lymph node status are important prognostic markers. Public awareness and screening may help in detecting the disease at an earlier stage. Prospectiv…