Taek-Seon Yun
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View article: Integrating allostasis and emerging technologies to study complex diseases
Integrating allostasis and emerging technologies to study complex diseases Open
The study of complex diseases has traditionally relied on reductionist methods, which, although informative, tend to overlook the dynamic interactions and systemic interconnectivity inherent in biological systems. Allostasis, a framework t…
View article: Environmental cues in different host niches shape the survival fitness of Staphylococcus aureus
Environmental cues in different host niches shape the survival fitness of Staphylococcus aureus Open
The ability of Staphylococcus aureus to adapt and thrive in diverse host niches adds to the challenge in combating this ubiquitous pathogen. While extensive research has been pursued on the adaptive mechanisms of methicillin-resistant S. a…
View article: Increased cellular uptake and proteasome inhibition of carfilzomib through the optimized self-nanoemulsifying drug delivery system
Increased cellular uptake and proteasome inhibition of carfilzomib through the optimized self-nanoemulsifying drug delivery system Open
Carfilzomib (CFZ) is a potent second-generation proteasome inhibitor that blocks the ubiquitin-proteasome pathway, inducing apoptosis in cancer cells. Currently, commercially available CFZ formulations contain large amounts of excipients, …
View article: Heavy metals promote the formation of multidrug-tolerant Staphylococcus aureus and Escherichia coli persisters
Heavy metals promote the formation of multidrug-tolerant Staphylococcus aureus and Escherichia coli persisters Open
Bacterial persisters are dormant phenotypic variants that are tolerant to antibiotics, contributing to treatment failure and the emergence of antimicrobial resistance. Although the formation of persisters has been extensively studied in re…
View article: Residual Characteristics of Trunk-Injected Oxolinic Acid for Control Fire Blight
Residual Characteristics of Trunk-Injected Oxolinic Acid for Control Fire Blight Open
View article: Enhanced Delivery of Sorafenib for Hepatocellular Carcinoma Treatment: Surface Modified PLGA Nanoparticles with Biomimetic Alterations
Enhanced Delivery of Sorafenib for Hepatocellular Carcinoma Treatment: Surface Modified PLGA Nanoparticles with Biomimetic Alterations Open
View article: Optimization Study of Leuprolide Acetate with Increased Permeability Through Hydrophobic Ion Pairing and Self-Nano Emulsifying Drug Delivery System for Oral Delivery
Optimization Study of Leuprolide Acetate with Increased Permeability Through Hydrophobic Ion Pairing and Self-Nano Emulsifying Drug Delivery System for Oral Delivery Open
View article: The Combinative Strategy for Improving the Intestinal Stability and Cellular Absorption of Curcumin by Enteric Coating of the Optimized Nanostructured Lipid Carriers
The Combinative Strategy for Improving the Intestinal Stability and Cellular Absorption of Curcumin by Enteric Coating of the Optimized Nanostructured Lipid Carriers Open