Explanipedia

Rare Hematological Disease of Paroxysmal Nocturnal Hemoglobinuria With Profound Implications for a Gastroenterologist: A Case Report and Literature Review Open

Swetha Parvataneni, Tagore Sunkara, Vinaya Gaduputi · 2020

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare type of thrombophilia and hematopoietic stem cell disorder characterized by mutation of the X-linked PIG-A gene. Patients with PNH present either with clinical features of intravascular h…

Acute Esophageal Necrosis: A Rare Case of Upper Gastrointestinal Bleeding from Diabetic Ketoacidosis Open

Dustin Uhlenhopp, Gregory Pagnotta, Tagore Sunkara · 2020

Acute esophageal necrosis, also known as black esophagus or acute necrotizing esophagitis is a rare condition with roughly 154 cases reported in the literature. This condition is classically diagnosed on its endoscopic findings of a circum…

Squamous Cell Papilloma of the Esophagus: A Case Series Highlighting Endoscopic and Histologic Features Open

Dustin Uhlenhopp, Kristin M. Olson, Tagore Sunkara · 2020

Esophageal squamous papillomas are rare epithelial lesions typically discovered incidentally during EGD. Their prevalence is estimated to be less than 0.01% in the general population. We present three cases of esophageal squamous papilloma…

Esophageal Cancer: An Updated Surveillance Epidemiology and End Results Database Analysis Open

Eric O. Then, Michell Lopez, Saad Saleem, Vijay Gayam, Tagore Sunkara , et al. · 2020

The incidence of esophageal adenocarcinoma in the USA is steadily on the rise. Conversely, the incidence of squamous cell carcinoma has been continually declining. While white males had an increased incidence of both types of esophageal ca…

Cirrhosis Is Associated With Worse Outcomes in Ischemic Colitis: A Nationwide Retrospective Study Open

Eric O. Then, C Lund, Dustin Uhlenhopp, Tagore Sunkara, Vinaya Gaduputi · 2020

The presence of cirrhosis is associated with increased odds of in-hospital mortality in those presenting with IC. This compounds the already high rates of mortality in patients that undergo surgery for IC and could reflect lack of reserve …

A Novel Approach for Management of Bleeding Stomal Varices: A Case Report of Ultrasound-Guided Percutaneous Sclerotherapy Open

Dustin Uhlenhopp, Kristin Olson, Tagore Sunkara · 2020

Ileostomy variceal bleeds can be a serious complication in patients with cirrhosis and ileostomy but make up a small portion of total variceal bleeds. Multiple modalities have been described as therapeutic options for stomal variceal bleed…

An Unpleasant Surprise: Abdominal Presentation of Malignant Mesothelioma Open

Dustin Uhlenhopp, Ann Saliares, Vinaya Gaduputi, Tagore Sunkara · 2020

Malignant mesothelioma is an aggressive cancer associated with asbestos exposure with median survival time of 8 to 14 months following diagnosis. Given that mesothelial cells also line the peritoneum and pericardium, malignant mesothelioma…

Eosinophilic gastroenteritis: diagnosis and clinical perspectives Open

Tagore Sunkara, P Rawla, Yarlagadda KS, Vinaya Gaduputi · 2019

Tagore Sunkara,1,2 Prashanth Rawla,3 Krishna Sowjanya Yarlagadda,1,2 Vinaya Gaduputi21Division of Gastroenterology and Hepatology, Mercy Medical Center, Des Moines, IA 50314, USA; 2Division of Gastroenterology, St. Barnabas Hospital Health…

Eosinophilic gastroenteritis: diagnosis and clinical perspectives Open

Tagore Sunkara, Prashanth Rawla, Krishna Sowjanya Yarlagadda, Vinaya Gaduputi · 2019

Eosinophilic gastroenteritis (EGE) is a digestive disorder in children and adults that is characterized by eosinophilic infiltration in the stomach and intestine. The underlying molecular mechanisms predisposing to this disease are unknown…

Herpes Simplex Virus Hepatitis: A Brief Review of an Oft-overlooked Pathology Open

Eric O. Then, Vijay Gayam, Vijay S. Are, Tagore Sunkara, Vinaya Gaduputi · 2019

Herpes simplex virus (HSV) is a rarely reported cause of viral hepatitis. Aggressive in nature, most cases of HSV hepatitis rapidly progress to fulminant hepatic failure. Present day, its pathogenesis is yet to be elucidated, but its compl…

EUS-guided thrombin injection of cystic artery pseudoaneurysm leading to Mirizzi’s syndrome and hemobilia Open

Malay Sharma, Piyush Somani, Rahul Talele, Vikas Kohli, Tagore Sunkara · 2019

A 52-year-old man presented with a history of right upper-abdominal pain for 7 days and melena for 3 days. General examination revealed tachycardia, pallor, and icterus. Abdominal examination showed normal results. Laboratory investigation…

New onset Heyde’s syndrome presenting after total aortic valve replacement Open

Eric O. Then, Carmine Catalano, Tagore Sunkara, Vinaya Gaduputi · 2019

Heyde's syndrome is a well-documented entity in the medical literature that can result in life-threatening gastrointestinal (GI) bleeding. It is a syndrome that is characterized by the combination of GI angioectasias and aortic stenosis. I…

Burkitt’s Lymphoma of the Gastrohepatic Omentum: A Malignant Presentation of Pseudoachalasia Open

Eric O. Then, Andrew Ofosu, Prashanth Rawla, Tagore Sunkara, Sriharsha Dadana , et al. · 2019

Achalasia is an intrinsic disorder of the esophagus that results from loss of ganglion cells in the lower esophageal sphincter. Clinically it is manifested by dysphagia to solids and liquids, weight loss, regurgitation, and chest pain. Pse…

Epidemiology of gallbladder cancer Open

Prashanth Rawla, Tagore Sunkara, Krishna Chaitanya Thandra, Adam Barsouk · 2019

According to GLOBOCAN 2018 data, gallbladder cancer (GBC) accounts for 1.2% of all global cancer diagnoses, but 1.7% of all cancer deaths. Only 1 in 5 GBC cases in the United States is diagnosed at an early stage, and median survival for a…

Epidemiology of Pancreatic Cancer: Global Trends, Etiology and Risk Factors Open

Prashanth Rawla, Tagore Sunkara, Vinaya Gaduputi · 2019

Pancreatic cancer is the seventh leading cause of cancer-related deaths worldwide. However, its toll is higher in more developed countries. Reasons for vast differences in mortality rates of pancreatic cancer are not completely clear yet, …

Epidemiology of colorectal cancer: incidence, mortality, survival, and risk factors Open

Prashanth Rawla, Tagore Sunkara, Adam Barsouk · 2019

According to GLOBOCAN 2018 data, colorectal cancer (CRC) is the third most deadly and fourth most commonly diagnosed cancer in the world. Nearly 2 million new cases and about 1 million deaths are expected in 2018. CRC incidence has been st…

An updated review of cystic hepatic lesions Open

Prashanth Rawla, Tagore Sunkara, Pradhyumna Muralidharan, Jeffrey Pradeep Raj · 2019

Cystic hepatic lesions are commonly encountered in daily practice. The diagnosis of these lesions ranges from benign lesions of no clinical significance to malignant and potentially lethal conditions. The prevalence of hepatic cyst (HC) ha…

Achalasia Cardia Resulting in Bronchial Obstruction: A Case Series and Literature Review Open

Eric O. Then, Tagore Sunkara, Febin John, Kishore Kumar Dewnani, Andrea Culliford , et al. · 2019

Achalasia is a motility disorder of the esophagus that is characterized by loss of ganglionic neurons within the myenteric plexus of the lower esophageal sphincter (LES) resulting in failure of the LES to relax. Clinically this disorder pr…

Potassium-competitive acid blockers - are they the next generation of proton pump inhibitors? Open

Prashanth Rawla, Tagore Sunkara, Andrew Ofosu, Vinaya Gaduputi · 2018

The modern lifestyle caters to an increase in the incidence of peptic ulcer disease, gastroesophageal reflux disease and several other acid-related conditions of the gut. The drugs to prevent these conditions work either through H2 recepto…

Endoscopic ultrasound-guided coil embolization and thrombin injection of a bleeding gastroduodenal artery pseudoaneurysm Open

Malay Sharma, Piyush Somani, Tagore Sunkara, Ritesh Prajapati, Rahul Talele · 2018

A 50-year-old man had an episode of alcohol-induced acute pancreatitis 1 month before presenting with melena, which required six units of transfused blood for hemodynamic stabilization. After hemodynamic resuscitation, the patient underwen…

Splenic hematoma may present as large bowel obstruction: A case report Open

Christine Kolwitz, Christopher Esposito, Caitlin Gauvin, Vinaya Gaduputi, Brian Chiong , et al. · 2018

Stepwise evaluation of liver sectors and liver segments by endoscopic ultrasound Open

Malay Sharma, Piyush Somani, C.S. Ramesh Babu, Tagore Sunkara, Praveer Rai · 2018

The liver has eight segments, which are referred to by numbers or by names. The numbering of the segments is done in a counterclockwise manner with the liver being viewed from the inferior surface, starting from Segment I (the caudate lobe…

Efficacy and Safety of Budesonide in the Treatment of Eosinophilic Esophagitis: Updated Systematic Review and Meta-Analysis of Randomized and Non-Randomized Studies Open

Prashanth Rawla, Tagore Sunkara, Krishna Chaitanya Thandra, Vinaya Gaduputi · 2018

Trichuris trichiura—An Unwelcome Surprise during Colonoscopy Open

Tagore Sunkara, Santosh Raj Sharma, Andrew Ofosu · 2018

Fecal microbiota transplant – a new frontier in inflammatory bowel disease Open

Tagore Sunkara, Prashanth Rawla, Andrew Ofosu, Vinaya Gaduputi · 2018

Inflammatory bowel disease (IBD) is a chronic multifactorial disease that affects the gastrointestinal tract and results from an aberrant immune response toward luminal antigens in genetically susceptible people. Most of the current therap…

Fecal microbiota transplant – a new frontier in inflammatory bowel disease Open

Tagore Sunkara, P Rawla, Andrew Ofosu, Vinaya Gaduputi · 2018

Tagore Sunkara,1 Prashanth Rawla,2 Andrew Ofosu,1 Vinaya Gaduputi3 1Division of Gastroenterology and Hepatology, The Brooklyn Hospital Center, Mount Sinai Health System, New York, NY, USA; 2Department of Internal Medicine, Sovah Health, Ma…

Mo1098 A META-ANALYSIS ON THE ROLE OF OVER THE SCOPE CLIPS AS A PRIMARY AND RESCUE THERAPY FOR NON-VARICEAL GI BLEEDING Open

Andrew Ofosu, Febin John, Douglas G. Adler, Santosh Sharma, Tagore Sunkara , et al. · 2018

Mo1112 SLICING VERSUS LOOPING-EFFICACY AND SAFETY OF ENDOSCOPIC SUBMUCOSAL DISSECTION(ESD) VERSUS ENDOSCOPIC MUCOSAL RESECTION(EMR) IN PATIENTS WITH NON-PEDUNCULATED POLYPS LARGER THAN 20MM Open

Andrew Ofosu, Daryl Ramai, Tagore Sunkara, Emmanuel Kwaku Ofori, Paul J. Fields , et al. · 2018

Gastric mucosal prolapse: A case of proton‐pump inhibitor nonresponsive dyspepsia Open

Tagore Sunkara, Emmanuel Kwaku Ofori, Krishna Sowjanya Yarlagadda, Vinaya Gaduputi · 2018

Key Clinical Message Gastric mucosal prolapse (GMP) is a rare clinical syndrome that in patients with hiatal hernias and gastroesophageal reflux disease ( GERD ) may present with typical findings of abdominal pain and reflux symptoms but p…

Endoscopic ultrasound-guided management of bleeding periampullary tumor Open

Malay Sharma, Piyush Somani, Tagore Sunkara, Ritesh Prajapati · 2018

A 72-year-old man presented with melena and a drop in hemoglobin from 10 g/dL to 5 g/dL. He required three units of blood for hemodynamic stabilization. He had undergone endoscopic retrograde cholangiopancreatography (ERCP) with biliary pl…

Tagore Sunkara YOU? Author Swipe