Tahereh Farkhondeh
YOU?
Author Swipe
View article: Investigation of the effect of chitosan-polycaprolactone scaffolds loaded with chrysin-capped silver nanoparticles in the healing of experimental cutaneous wound defects in rat
Investigation of the effect of chitosan-polycaprolactone scaffolds loaded with chrysin-capped silver nanoparticles in the healing of experimental cutaneous wound defects in rat Open
View article: Berberine nanoemulsion attenuates bisphenol A-induced metabolic impairment through NF-κB signaling in the liver of rat
Berberine nanoemulsion attenuates bisphenol A-induced metabolic impairment through NF-κB signaling in the liver of rat Open
View article: Effect of Chrysin and Chrysin Nanocrystals on Chlorpyrifos-Induced Dysfunction of the Hypothalamic-Pituitary-Testicular Axis in Rats
Effect of Chrysin and Chrysin Nanocrystals on Chlorpyrifos-Induced Dysfunction of the Hypothalamic-Pituitary-Testicular Axis in Rats Open
Aims and Background: The escalating global concerns regarding reproductive health underscore the urgency of investigating the impact of environmental pollutants on fertility. This study aims to focus on Chlorpyrifos (CPF), a widely-used or…
View article: Corrigendum to “Oxidative stress and apoptotic index modifications in the hippocampus of rat pups born to mothers exposed to buprenorphine during lactation” [Toxicol. Rep. 2022 Nov 19; 9: 2050–2054. doi: 10.1016/j.toxrep.2022.11.005. PMID: 36518388; PMCID: PMC9742962]
Corrigendum to “Oxidative stress and apoptotic index modifications in the hippocampus of rat pups born to mothers exposed to buprenorphine during lactation” [Toxicol. Rep. 2022 Nov 19; 9: 2050–2054. doi: 10.1016/j.toxrep.2022.11.005. PMID: 36518388; PMCID: PMC9742962] Open
[This corrects the article DOI: 10.1016/j.toxrep.2022.11.005.].
View article: Nrf2 Mediates Effect of Resveratrol in Ischemia-reperfusion Injury
Nrf2 Mediates Effect of Resveratrol in Ischemia-reperfusion Injury Open
: Ischemia-Reperfusion Injury (IRI) is a paradoxical phenomenon where removing the source of injury can cause additional damage. Ischemia reduces ATP production and intracellular pH, reducing oxidative reactions, increasing lactic acid rel…
View article: A Review of the Dual Role of MicroRNA-21 in Cardiovascular Diseases: RiskFactor or a Potential Therapeutic Target
A Review of the Dual Role of MicroRNA-21 in Cardiovascular Diseases: RiskFactor or a Potential Therapeutic Target Open
Cardiovascular diseases [CVD] are the number one reason for morbidity and mortality in the modern world, and their incidence is increasing at an incredible pace. Increasing evidence has shown the significant functions of microRNAs in the c…
View article: Anticancer Properties of Baicalin against Breast Cancer and otherGynecological Cancers: Therapeutic Opportunities based on UnderlyingMechanisms
Anticancer Properties of Baicalin against Breast Cancer and otherGynecological Cancers: Therapeutic Opportunities based on UnderlyingMechanisms Open
Gynecological cancers are serious life-threatening diseases responsible for high morbidity and mortality around the world. Chemotherapy, radiotherapy, and surgery are considered standard therapeutic modalities for these cancers. Since the …
View article: Carbamate compounds induced toxic effects by affecting Nrf2 signaling pathways
Carbamate compounds induced toxic effects by affecting Nrf2 signaling pathways Open
Carbamate (CBs) is a class of insecticides which is being known as an important cause of intentional or accidental poisoning. CBs, cause carbamylation of acetylcholinesterase at neuronal synapses and neuromuscular junction. Exposure to CBs…
View article: Total Joint Arthroplasty in Patients With Parkinson’s Disease: A Review of Recent Literature
Total Joint Arthroplasty in Patients With Parkinson’s Disease: A Review of Recent Literature Open
View article: Anticancer activity of thymoquinone against breast cancer cells: Mechanisms of action and delivery approaches
Anticancer activity of thymoquinone against breast cancer cells: Mechanisms of action and delivery approaches Open
The rising incidence of breast cancer has been a significant source of concern in the medical community. Regarding the adverse effects and consequences of current treatments, cancers' health, and socio-economical aspects have become more c…
View article: Protective Effect of Chrysin against Chlorpyrifos-Induced MetabolicImpairment and Pancreatitis in Male Rats
Protective Effect of Chrysin against Chlorpyrifos-Induced MetabolicImpairment and Pancreatitis in Male Rats Open
Background:: This study was performed to evaluate the protective effects of chrysin (CH) on metabolic impairment and pancreatic injury caused by sub-chronic chlorpyrifos (CPF) intoxication in male rats. METHODS: Forty male Wistar rats were…
View article: Role of miRNAs in mediating organophosphate compounds induced toxicity
Role of miRNAs in mediating organophosphate compounds induced toxicity Open
Organophosphate compounds (OPCs) are a diverse class of chemicals utilized in both industrial and agricultural settings. The exact molecular pathways that OPCs-induced toxicity is caused by are still being investigated, despite the fact th…
View article: Protective effect of Sophora pachycarpa seed extract on carbon tetrachloride-induced toxicity in rats
Protective effect of Sophora pachycarpa seed extract on carbon tetrachloride-induced toxicity in rats Open
The aim of the present study was to investigate the protective effect of the Sophora pachycarpa (S. pachycarpa) seed extract against carbon tetrachloride-induced toxicity on body organs, blood, and biochemical factors. In this investigatio…
View article: The interplay between oxidative stress and autophagy: focus on the development of neurological diseases
The interplay between oxidative stress and autophagy: focus on the development of neurological diseases Open
View article: Oxidative stress and apoptotic index modifications in the hippocampus of rat pups born to mothers exposed to buprenorphine during lactation
Oxidative stress and apoptotic index modifications in the hippocampus of rat pups born to mothers exposed to buprenorphine during lactation Open
View article: Additional file 1 of Protective effect of Sophora pachycarpa seed extract on carbon tetrachloride-induced toxicity in rats
Additional file 1 of Protective effect of Sophora pachycarpa seed extract on carbon tetrachloride-induced toxicity in rats Open
Additional file 1.
View article: Effects of exposure in utero to buprenorphine on oxidative stress and apoptosis in the hippocampus of rat pups
Effects of exposure in utero to buprenorphine on oxidative stress and apoptosis in the hippocampus of rat pups Open
The study investigated the effect of buprenorphine (BUP) on oxidative indices and gene expression of apoptotic molecules in the hippocampus of neonates during the fetal stage. BUP (1 or 0.5 mg/kg) was subcutaneously administrated to pregna…
View article: Anti-inflammatory action of astaxanthin and its use in the treatment of various diseases
Anti-inflammatory action of astaxanthin and its use in the treatment of various diseases Open
Astaxanthin (AST) is a red pigmented carotenoid with significant antioxidant, anti-inflammatory, anti-proliferative, and anti-apoptotic properties. In this study, we summarize the available literature on the anti-inflammatory efficacy of A…
View article: Resveratrol mediates its anti-cancer effects by Nrf2 signaling pathway activation
Resveratrol mediates its anti-cancer effects by Nrf2 signaling pathway activation Open
Aim and background Cancer represents a major health problem with an exceedingly high toll on the patients, their families, and the economy. Cancers are also associated with high mortality rates. Existing therapies for cancer are generally …
View article: STAT3 pathway as a molecular target for resveratrol in breast cancer treatment
STAT3 pathway as a molecular target for resveratrol in breast cancer treatment Open
View article: An Overview of NO Signaling Pathways in Aging
An Overview of NO Signaling Pathways in Aging Open
Nitric Oxide (NO) is a potent signaling molecule involved in the regulation of various cellular mechanisms and pathways under normal and pathological conditions. NO production, its effects, and its efficacy, are extremely sensitive to agin…
View article: An updated review on the versatile role of chrysin in neurological diseases: Chemistry, pharmacology, and drug delivery approaches
An updated review on the versatile role of chrysin in neurological diseases: Chemistry, pharmacology, and drug delivery approaches Open
Neurological diseases are responsible for a large number of morbidities and mortalities in the world. Flavonoids are phytochemicals that possess various health-promoting impacts. Chrysin, a natural flavonoid isolated from diverse fruits, v…
View article: Molecular and cellular pathways contributing to brain aging
Molecular and cellular pathways contributing to brain aging Open
View article: Molecular targets for the management of gastrointestinal cancer using melatonin, a natural endogenous body hormone
Molecular targets for the management of gastrointestinal cancer using melatonin, a natural endogenous body hormone Open
View article: Roles of Nrf2 in Gastric Cancer: Targeting for Therapeutic Strategies
Roles of Nrf2 in Gastric Cancer: Targeting for Therapeutic Strategies Open
Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) is a specific transcription factor with potent effects on the regulation of antioxidant gene expression that modulates cell hemostasis under various conditions in tissues. However, the eff…
View article: Emerging cellular and molecular mechanisms underlying anticancer indications of chrysin
Emerging cellular and molecular mechanisms underlying anticancer indications of chrysin Open
View article: Impact of Metformin on Cancer Biomarkers in Non-Diabetic Cancer Patients: A Systematic Review and Meta-Analysis of Clinical Trials
Impact of Metformin on Cancer Biomarkers in Non-Diabetic Cancer Patients: A Systematic Review and Meta-Analysis of Clinical Trials Open
Introduction: Our aim was to investigate and evaluate the influence of metformin on cancer-related biomarkers in clinical trials. Methods: This systematic study was conducted according to Preferred Reporting Items for Systematic Reviews an…
View article: Anti-inflammatory effects of thymoquinone and its protective effects against several diseases
Anti-inflammatory effects of thymoquinone and its protective effects against several diseases Open
View article: Therapeutic Potential of Saffron (Crocus sativus L.) in Ischemia Stroke
Therapeutic Potential of Saffron (Crocus sativus L.) in Ischemia Stroke Open
Stroke is the second leading cause of death and a main cause of disability worldwide. The majority (approximately 80%) of strokes are ischemic. Saffron (Crocus sativus L.) has been considered for medicinal purposes since ancient times. Pha…
View article: Nrf2 a molecular therapeutic target for Astaxanthin
Nrf2 a molecular therapeutic target for Astaxanthin Open
Astaxanthin (ATX) is a red pigment carotenoid present in shrimp, salmon, crab, and asteroidean. Several studies have corroborated the anti-oxidant efficacy of ATX. In addition, ATX has anti-inflammatory, anti-apoptotic and anti-proliferati…