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View article: Properties of bioceramic materials for endodontic use
Properties of bioceramic materials for endodontic use Open
Aim: Review the characteristics of endodontic bioceramics in comparison with other endodontic materials using the currently available literature. Methods: A bibliographical research was carried out using the electronic databases Public Med…
View article: Montrichardia linifera (Arruda) Schott promotes accelerated wound healing in vitro: a promising healing
Montrichardia linifera (Arruda) Schott promotes accelerated wound healing in vitro: a promising healing Open
Introduction Montrichardia linifera (Arruda) Schott ( M. linifera ) is commonly used by Amazonian riverine communities for the treatment of skin ulcers, although its effects as a wound healer have never been evaluated until now. Therefore,…
View article: Antibacterial, antibiofilm and viability analysis in vitro of calcium silicate and epoxy resin-based filling sealers
Antibacterial, antibiofilm and viability analysis in vitro of calcium silicate and epoxy resin-based filling sealers Open
Aim: The aim of this study was to evaluate the antibacterial and antibiofilm capacity against Enterococcus faecalis of endodontic sealers AH Plus Jet and the calcium silicate-based sealers, Bio-C Sealer and Sealer Plus BC. Methods: All exp…
View article: Antibiofilm, regenerative and bone homeostasis potential of the synergistic association of synoeca-MP peptide with chlorhexidine in oral cavity opportunistic infections
Antibiofilm, regenerative and bone homeostasis potential of the synergistic association of synoeca-MP peptide with chlorhexidine in oral cavity opportunistic infections Open
Objective To evaluate in vitro the association between synoeca-MP peptide and chlorhexidine, regarding their antimicrobial and antibiofilm activities, saliva stability, effect on tissue repair, bone resorption processes, and mineralized ma…
View article: Senotherapeutic Peptide 14 Suppresses Th1 and M1 Human T Cell and Monocyte Subsets In Vitro
Senotherapeutic Peptide 14 Suppresses Th1 and M1 Human T Cell and Monocyte Subsets In Vitro Open
Inflammation contributes to the onset and exacerbation of numerous age-related diseases, often manifesting as a chronic condition during aging. Given that cellular senescence fosters local and systemic inflammation, senotherapeutic interve…
View article: IFN‐<i>γ</i>‐Licensed Mesenchymal Stem Cells Are More Susceptible to Death when Exposed to Quorum‐Sensing Signal Molecule OdDHL and Less Effective in Inhibiting the Growth of <i>Pseudomonas aeruginosa</i>
IFN‐<i>γ</i>‐Licensed Mesenchymal Stem Cells Are More Susceptible to Death when Exposed to Quorum‐Sensing Signal Molecule OdDHL and Less Effective in Inhibiting the Growth of <i>Pseudomonas aeruginosa</i> Open
Currently, a series of licensing strategies has been investigated to enhance the functional properties of mesenchymal stem cells (MSCs). Licensing with IFN‐ γ is one of the most investigated strategies for enhancing the immunosuppressive p…
View article: Editorial: Global excellence in dental medicine: South America
Editorial: Global excellence in dental medicine: South America Open
EDITORIAL article Front. Dent. Med, 28 November 2023Sec. Periodontics Volume 4 - 2023 | https://doi.org/10.3389/fdmed.2023.1333268
View article: Association between host defense peptide IDR-1002 and ciprofloxacin: effects on human dental pulp cells
Association between host defense peptide IDR-1002 and ciprofloxacin: effects on human dental pulp cells Open
Aim: to evaluate the effects of the association of host defense peptide IDR-1002 and ciprofloxacin on human dental pulp cells (hDPSCs). Materials and methods: hDPSCs were stimulated in culture with ciprofloxacin and IDR-1002. Cell viabilit…
View article: Host defense peptides combined with MTA extract increase the repair in dental pulp cells: in vitro and ex vivo study
Host defense peptides combined with MTA extract increase the repair in dental pulp cells: in vitro and ex vivo study Open
View article: Triclosan antimicrobial activity against dental-caries-related bacteria
Triclosan antimicrobial activity against dental-caries-related bacteria Open
Triclosan (TCS) is a chlorinated diphenyl ether and a possible active agent against microorganisms. Due to its probability of reducing dental plaque accumulation, TCS can be added as a substance for oral hygiene. Aim: To evaluate the effic…
View article: Evaluation of the biotechnological potential of peptide Cupiennin 1a and analogs
Evaluation of the biotechnological potential of peptide Cupiennin 1a and analogs Open
Antimicrobial peptides (AMPs) are components in the innate immune system of various organisms, and many AMPs can be found in poisons from animals such as spiders, scorpions, and snakes. The peptide Cupiennin-1a is present in the venom of t…
View article: Antibiofilm and immunomodulatory resorbable nanofibrous filing for dental pulp regenerative procedures
Antibiofilm and immunomodulatory resorbable nanofibrous filing for dental pulp regenerative procedures Open
View article: HIPERGLICEMIA CRÔNICA E A PRODUÇÃO DE ÓXIDO NÍTRICO IN VITRO
HIPERGLICEMIA CRÔNICA E A PRODUÇÃO DE ÓXIDO NÍTRICO IN VITRO Open
pela Reflexão Acadêmica Editora, é uma coletânea que une onze capítulos que discorrem sobre temas relacionados com as diversas áreas da saúde.Assim, os trabalhos discutem, avaliação da função vestibular, que visa analisar exames usado para…
View article: The Effects of High-Protein Diet and Resistance Training on Glucose Control and Inflammatory Profile of Visceral Adipose Tissue in Rats
The Effects of High-Protein Diet and Resistance Training on Glucose Control and Inflammatory Profile of Visceral Adipose Tissue in Rats Open
High-protein diets (HPDs) are widely accepted as a way to stimulate muscle protein synthesis when combined with resistance training (RT). However, the effects of HPDs on adipose tissue plasticity and local inflammation are yet to be determ…
View article: COVID-19 e atenção a pessoas com deficiência e grupos especiais na clínica-escola de Odontologia
COVID-19 e atenção a pessoas com deficiência e grupos especiais na clínica-escola de Odontologia Open
O presente artigo tem como finalidade abordar orientações e sugestões para o atendimento odontológico de pacientes com necessidades especiais (pessoas com deficiência) e idosos nas clínicas de graduação, considerando as implicações da COVI…
View article: Host defense peptides clavanins A and MO reduce in vitro osteoclastogenesis
Host defense peptides clavanins A and MO reduce in vitro osteoclastogenesis Open
Aim: Several systemic diseases, such as periodontitis and apical periodontitis, can cause extensive bone resorption. Host defense peptides may have the potential for the development of novel therapies for the bone resorption process. This …
View article: Systemic conditions of diabetic patients diagnosed with apical periodontitis
Systemic conditions of diabetic patients diagnosed with apical periodontitis Open
Objective: This study aimed to evaluate the association between glycemic control status in type 2 diabetes mellitus (T2DM) patients and apical periodontitis. Methods: Twenty-seven patients were involved in this study. The survey was based …
View article: Mineral trioxide aggregate (MTA) inhibits osteoclastogenesis and osteoclast activation through calcium and aluminum activities
Mineral trioxide aggregate (MTA) inhibits osteoclastogenesis and osteoclast activation through calcium and aluminum activities Open
View article: Physicochemical-guided design of cathelicidin-derived peptides generates membrane active variants with therapeutic potential
Physicochemical-guided design of cathelicidin-derived peptides generates membrane active variants with therapeutic potential Open
View article: Enterococcus faecalis and Staphylococcus aureus stimulate nitric oxide production in macrophages and fibroblasts in vitro
Enterococcus faecalis and Staphylococcus aureus stimulate nitric oxide production in macrophages and fibroblasts in vitro Open
Aim: Nitric oxide (NO) is an important mediator related to damage of the pulp tissue and at the same time to regenerative pulp processes. However, it is not clear how common endodontic microorganisms can regulate this mediator. This study …
View article: Issue Information
Issue Information Open
View article: Scanning Electron Microscopic/Energy-Dispersive X-Ray Analysis in Cases of Apical Periodontitis Refractory to Endodontic Treatment: A Case Series Study.
Scanning Electron Microscopic/Energy-Dispersive X-Ray Analysis in Cases of Apical Periodontitis Refractory to Endodontic Treatment: A Case Series Study. Open
This study aimed to present a case series of refractory endodontic treatment leading to persistent apical periodontitis. All cases were submitted to scanning electron microscopic/energy-dispersive X-ray analysis (SEM/EDS) of the external s…
View article: An acidic model pro-peptide affects the secondary structure, membrane interactions and antimicrobial activity of a crotalicidin fragment
An acidic model pro-peptide affects the secondary structure, membrane interactions and antimicrobial activity of a crotalicidin fragment Open
In order to study how acidic pro-peptides inhibit the antimicrobial activity of antimicrobial peptides, we introduce a simple model system, consisting of a 19 amino-acid long antimicrobial peptide, and an N-terminally attached, 10 amino-ac…
View article: Antimicrobial Peptides and Nanotechnology, Recent Advances and Challenges
Antimicrobial Peptides and Nanotechnology, Recent Advances and Challenges Open
Antimicrobial peptides are sequences of amino acids, which present activity against microorganisms. These peptides were discovered over 70 years ago, and are abundant in nature from soil bacteria, insects, amphibians to mammals and plants.…
View article: An Immunomodulatory Peptide Confers Protection in an Experimental Candidemia Murine Model
An Immunomodulatory Peptide Confers Protection in an Experimental Candidemia Murine Model Open
Fungal Candida species are commensals present in the mammalian skin and mucous membranes. Candida spp. are capable of breaching the epithelial barrier of immunocompromised patients with neutrophil and cell-mediated immune dysfunctions and …
View article: An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities
An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities Open
View article: An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities
An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities Open
View article: Experimental Furcal Perforation Treated with MTA: Analysis of the Cytokine Expression
Experimental Furcal Perforation Treated with MTA: Analysis of the Cytokine Expression Open
The aim of this study was to evaluate mineral trioxide aggregate (MTA)-induced cytokine expression in mice after experimental furcal perforation. BALB/c mice (n=5) were subjected to induced furcal drilling of the maxillary first molar foll…