Explanipedia

Yerba Maté and its impact on glycemic control and metabolic health: a systematic review and meta-analysis Open

Daiping Li, Li-min Yue, Xuchao Peng, Ling Chen, Taiping Lin , et al. · 2025

Purpose Yerba Maté, a traditional South American herbal infusion abundant in bioactive compounds, has been suggested to offer health benefits including lipid regulation and weight management. However, existing evidence remains inconclusive…

The synergy between life’s essential 8 and muscle strength on cardiovascular disease risk Open

Linlong Li, Jianhong Xu, Xiangping Tu, Taiping Lin, Jirong Yue , et al. · 2025

Background While muscle strength is a known CVD risk factor in aging, its influence across the spectrum of Life’s Essential 8 (LE8) scores - the American Heart Association’s (AHA’s) comprehensive metric of cardiovascular health that includ…

Pain trajectories in relation to incident functional limitation among older adults: A prospective cohort study Open

Qiao Xiang, Yuxiao Li, Ziyi Zhong, Wei Huang, Junyi Chu , et al. · 2025

Diagnostic performance of the systemic immune-inflammation index (SII) and sarcopenia index (SI) in sarcopenia and their prognostic value for clinical outcomes in hospitalized older patients Open

Xiangping Tu, Taiping Lin, Li Huang, Tingting Jiang, Qin Zheng , et al. · 2025

The combination of SII with CC and SI with CC demonstrated advantageous diagnostic accuracy in diagnosing sarcopenia compared to SII and SI used independently. SII may serve as a serum indicator for predicting all-cause mortality in hospit…

Development and validation of PRE-FRA (PREdiction of FRAilty risk in community older adults) frailty prediction model Open

Taiping Lin, Xiaotao Huang, Xiang Wang, Miao Dai, Jirong Yue · 2025

Background As the global population ages, identifying older adults at risk of frailty becomes increasingly important for targeted interventions. This study aimed to develop and validate a 1-year frailty onset prediction model for initially…

Sarcopenia and risk of postoperative pneumonia: a systematic review and meta-analysis Open

Xiaoyu Shu, Quhong Song, Xiaoli Huang, Tianjiao Tang, Li Huang , et al. · 2024

Our research findings indicate that preoperative sarcopenia significantly increases the risk of postoperative pneumonia. Future high-quality prospective studies and intervention studies are needed to validate the relationship between sarco…

Creatinine-to-cystatin C ratio and frailty in older adults: a longitudinal cohort study Open

Quhong Song, Taiping Lin, Rui Liang, Yanli Zhao, Ning Ge , et al. · 2024

Higher CCR was associated with a lower frailty risk. CCR may be a simple marker for predicting frailty in older adults.

Exploring the impact of interleukins on sarcopenia development: A systematic review and meta-analysis Open

Yan He, Wenrong Duan, Ping Xu, Taiping Lin, Qiao Xiang , et al. · 2024

CRD42024506656.

Identification of nicotinamide N‐methyltransferase as a promising therapeutic target for sarcopenia Open

Rui Liang, Qiao Xiang, Miao Dai, Taiping Lin, Dongmei Xie , et al. · 2024

Sarcopenia is a significant geriatric syndrome that involves the loss of skeletal muscle mass and strength. Due to its substantial endocrine role, the metabolic microenvironment of skeletal muscle undergoes changes with age. Examining the …

Sarcopenia in systemic sclerosis: prevalence and impact—a systematic review and meta-analysis Open

Xiangping Tu, Taiping Lin, Yuan Ju, Xiaoyu Shu, Tingting Jiang , et al. · 2024

Objective This review aims to provide an estimate of sarcopenia prevalence and its impact on clinical characteristics in patients with systemic sclerosis (SSc). Design Systematic review and meta-analysis. Data sources Embase, Medline, Web …

Corrigendum: Tooth loss, denture use, and all-cause and cause-specific mortality in older adults: a community cohort study Open

Miao Dai, Quhong Song, Taiping Lin, Xiaohong Huang, Yufang Xie , et al. · 2024

[This corrects the article DOI: 10.3389/fpubh.2023.1194054.].

Prevalence and prognostic value of baseline sarcopenia in hematologic malignancies: a systematic review Open

Xiaofeng Zeng, Liying Zhang, Yu Zhang, Shuli Jia, Taiping Lin , et al. · 2023

Background The correlation between sarcopenia and hematological malignancy prognosis is still controversial. Design: A systematic review and meta-analysis. Objectives: To explore sarcopenia’s prevalence and prognostic value in hematologic …

Is waist-calf circumference ratio associated with frailty in older adults? Findings from a cohort study Open

Miao Dai, Quhong Song, Jirong Yue, Taiping Lin, Wei Jie , et al. · 2023

Tooth loss, denture use, and all-cause and cause-specific mortality in older adults: a community cohort study Open

Miao Dai, Quhong Song, Taiping Lin, Xiaohong Huang, Yufang Xie , et al. · 2023

Objectives The available evidence on the connections between tooth loss, denture use, and mortality from all causes or specific causes among older adults is inconclusive. Therefore, we aimed to investigate the association between tooth los…

Combined associations of vitamin D and cognitive function with all-cause mortality among older adults in Chinese longevity areas: A prospective cohort study Open

Miao Dai, Quhong Song, Xiang Wang, Ying Li, Taiping Lin , et al. · 2023

Objectives While both vitamin D deficiency and cognitive impairment have individually been linked to a greater risk of all-cause mortality, the combined effects of these two different conditions have not previously been explored in this co…

Biomass fuel usage for cooking and frailty among older adults in China: a population-based cohort study Open

Quhong Song, Miao Dai, Taiping Lin, Yanli Zhao, Xuchao Peng , et al. · 2023

Background Although outdoor air pollution is reported to have a negative effect on frailty, evidence involving household air pollution is sparse. Methods A cohort study on older participants aged ≥65 years from the Chinese Longitudinal Hea…

Perivascular spaces visible on magnetic resonance imaging predict subsequent delirium in older patients Open

Quhong Song, Yanli Zhao, Taiping Lin, Jirong Yue · 2022

Background It remains unknown whether perivascular spaces (PVS) are associated with delirium in older hospitalized patients. We aimed to determine the association between magnetic resonance imaging (MRI)-visible PVS and the risk of deliriu…

Reliability and validity of two hand dynamometers when used by community-dwelling adults aged over 50 years Open

Li Huang, Yadong Liu, Taiping Lin, Lisha Hou, Quhong Song , et al. · 2022

The Impact of Vitamin D and Cognitive Function on All-Cause Mortality Among Older Chinese Adults: A Population-based Longitudinal Study Open

Miao Dai, Quhong Song, Xiang Wang, Taiping Lin, Rui Liang , et al. · 2022

Background While both vitamin D deficiency and cognitive impairment have individually been linked to a greater risk of all-cause mortality, the combined effects of these two different conditions have not previously been explored in this co…

Prevalence and prognostic value of preexisting sarcopenia in patients with mechanical ventilation: a systematic review and meta-analysis Open

Tingting Jiang, Taiping Lin, Xiaoyu Shu, Quhong Song, Miao Dai , et al. · 2022

Combined Vision and Hearing Impairment is Associated with Frailty in Older Adults: Results from the West China Health and Aging Trend Study Open

Yanli Zhao, Qunfang Ding, Taiping Lin, Xiaoyu Shu, Dongmei Xie , et al. · 2022

Older adults with dual sensory impairment are more likely to be frail than those with no impairment, suggesting that interventions to improve sensory function may potentially help reduce the risk of frailty in older adults.

Association between stress hyperglycemia ratio and delirium in older hospitalized patients: a cohort study Open

Quhong Song, Miao Dai, Yanli Zhao, Taiping Lin, Huang Li , et al. · 2022

Background It remains unclear whether stress hyperglycemia is associated with delirium. We performed this cohort study to determine the association between stress hyperglycemia and delirium. Methods We consecutively enrolled patients aged …

Barriers to prescribing oral anticoagulants to inpatients aged 80 years and older with nonvalvular atrial fibrillation: a cross-sectional study Open

Xin Xia, Lishuang Wang, Taiping Lin, Jirong Yue, Zhonghua Yang , et al. · 2022

Background To investigate the temporal trend of the prevalence of underprescription of anticoagulation treatment and explore the factors associated with underprescription of oral anticoagulants (OACs) among inpatients aged ≥ 80 years with …

Barriers to Prescribing Oral Anticoagulants To Inpatients Aged 80 Years and Older With Nonvalvular Atrial Fibrillation: A Cross-Sectional Study Open

Xin Xia, Lishuang Wang, Taiping Lin, Jirong Yue, Zhonghua Yang , et al. · 2022

Background: To investigate the temporal trend of prevalence of anticoagulation treatment and explore the factors associated with under prescription of oral anti-coagulants (OACs) among inpatients aged ≥80 years with nonvalvular atrial fibr…

[Research of relationship between frailty and gut microbiota on middle-aged and the aged patients with diabetes]. Open

Xuchao Peng, Yanli Zhao, Taiping Lin, Xiaoyu Shu, Lisha Hou , et al. · 2021

Gut microbiota plays an important role in development of diabetes with frailty. Therefore, it is of great significance to study the structural and functional characteristics of gut microbiota in Chinese with frailty. Totally 30 middle-aged…

Effects of Circulating 25(OH)D Status in Advanced Colorectal Cancer Patients Undergoing Chemotherapy: A Systematic Review Open

Xiaofeng Zeng, Liying Zhang, Shuli Jia, Taiping Lin, Gongxiang Liu , et al. · 2021

High circulating 25(OH)D content is beneficial for improving prognosis of advanced CRC receiving chemotherapy.

Risk Factors for Delirium in the Palliative Care Population: A Systematic Review and Meta-Analysis Open

Duan Guo, Taiping Lin, Chuanyao Deng, Yuxia Zheng, Langli Gao , et al. · 2021

Objective: Delirium is common and highly distressing for the palliative care population. Until now, no study has systematically reviewed the risk factors of delirium in the palliative care population. Therefore, we performed a systematic r…

Signatures and Clinical Significance of Amino Acid Flux in Sarcopenia: A Systematic Review and Meta-Analysis Open

Miao Dai, Taiping Lin, Jirong Yue, Lunzhi Dai · 2021

Background Dysregulation of amino acids is closely linked to the initiation and progression of sarcopenia. We summarized recent advancements in the studies of amino acid profiles in sarcopenia and systematically presented the clinical sign…

Association Between Geriatric Nutritional Risk Index and Frailty in Older Hospitalized Patients Open

Yanli Zhao, Taiping Lin, Lisha Hou, Meng Zhang, Xuchao Peng , et al. · 2021

Nutrition-related risk screened by the GNRI was independently associated with frailty. The GNRI could be used as a simple tool in detecting nutritional risk and frailty status of older patients.

Neutrophil-lymphocyte ratio as a predictor of delirium in older internal medicine patients: a prospective cohort study Open

Yanli Zhao, Jirong Yue, Peng Lei, Taiping Lin, Xuchao Peng , et al. · 2021

Backgrounds Delirium is a common neuropsychiatric syndrome in older hospitalized patients. Previous studies have suggested that inflammation and oxidative stress contribute to the pathophysiology of delirium. However, it remains unclear wh…

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