Tairo Oshima
YOU?
Author Swipe
View article: Caldomycin, a new guanidopolyamine produced by a novel agmatine homocoupling enzyme involved in homospermidine biosynthesis
Caldomycin, a new guanidopolyamine produced by a novel agmatine homocoupling enzyme involved in homospermidine biosynthesis Open
An extreme thermophilic bacterium, Thermus thermophilus produces more than 20 unusual polyamines, but their biosynthetic pathways, including homospermidine, are not yet fully understood. Two types of homospermidine synthases have been iden…
View article: Caldomycin, a new guanidopolyamine produced by a novel agmatine homocoupling enzyme involved in homospermidine biosynthesis
Caldomycin, a new guanidopolyamine produced by a novel agmatine homocoupling enzyme involved in homospermidine biosynthesis Open
An extreme thermophilic bacterium, Thermus thermophilus produces more than 20 unusual polyamines, but their biosynthetic pathways, including homospermidine, are not yet fully understood. Two types of homospermidine synthases have been iden…
View article: Putrescine Biosynthesis from Agmatine by Arginase (TtARG) in <i>Thermus thermophilus</i>
Putrescine Biosynthesis from Agmatine by Arginase (TtARG) in <i>Thermus thermophilus</i> Open
In the three domains of life, three biosynthetic pathways are known for putrescine. The first route is conversion of ornithine to putrescine by ornithine decarboxylase (ODC: SpeC), the second route is the conversion of arginine to agmatine…
View article: ThermusQ: Toward the cell simulation platform for <i>Thermus thermophilus</i>
ThermusQ: Toward the cell simulation platform for <i>Thermus thermophilus</i> Open
ThermusQ is a website (https://www.thermusq.net/) that aims to gather all the molecular information on Thermus thermophilus and to provide a platform to easily access the whole view of the bacterium. ThermusQ comprises the genome sequences…
View article: A new metabolic pathway for <i>sym</i>-homospermidine synthesis in an extreme thermophile, <i>Thermus thermophilus.</i>
A new metabolic pathway for <i>sym</i>-homospermidine synthesis in an extreme thermophile, <i>Thermus thermophilus.</i> Open
In an extreme thermophile, Thermus thermophilus, sym-homospermidine is synthesized by the actions of two enzymes. The first enzyme coded by dhs gene (annotated to be deoxyhypusine synthase gene) catalyzes synthesis of an intermediate, supp…
View article: Verification of Effects on Crops and Surrounding Environment in Agriculture Using Radioactively Contaminated Grass Silage Compost Made by Aerobic Ultrahigh Temperature Fermentation
Verification of Effects on Crops and Surrounding Environment in Agriculture Using Radioactively Contaminated Grass Silage Compost Made by Aerobic Ultrahigh Temperature Fermentation Open
The Fukushima Daiichi Nuclear Power Plant (Tokyo Electric Power Co. Ltd.) accident caused by the Great East Japan Earthquake (11 March 2011) contaminated farmland, grassland, and grass silage in the Tohoku region of Japan with radioactive …
View article: <i>Thermus thermophilus</i> polyploid cells directly imaged by X-ray laser diffraction
<i>Thermus thermophilus</i> polyploid cells directly imaged by X-ray laser diffraction Open
Thermus thermophilus is reportedly polyploid and carries four to five identical genome copies per cell, based on molecular biological experiments. To directly detect polyploidy in this bacterium, we performed live cell imaging by X-ray fre…
View article: Isolation and genomic analysis of a type IV pili-independent <i>Thermus thermophilus</i> phage, φMN1 from a Japanese hot spring
Isolation and genomic analysis of a type IV pili-independent <i>Thermus thermophilus</i> phage, φMN1 from a Japanese hot spring Open
A Thermus thermophilus lytic phage was isolated from a Japanese hot spring using a type IV pili-deficient strain as an indicator host, and designated as φMN1. Electron microscopic (EM) examination revealed that φMN1 had an icosahedral head…
View article: Alkaline Stress Causes Changes in Polyamine Biosynthesis in Thermus thermophilus
Alkaline Stress Causes Changes in Polyamine Biosynthesis in Thermus thermophilus Open
An extreme thermophile, Thermus thermophilus, produces 16 different polyamines including long-chain and branched-chain polyamines. The composition and content of polyamines in the thermophile cells change not only with growth temperature b…
View article: Complete Genome Sequences of Thermus thermophilus Strains HB5002 and HB5008, Isolated from Mine Hot Spring in Japan
Complete Genome Sequences of Thermus thermophilus Strains HB5002 and HB5008, Isolated from Mine Hot Spring in Japan Open
We isolated Thermus thermophilus strains HB5002 and HB5008 from Mine Hot Spring in Japan. Whole-genome sequencing revealed that they showed ∼100% average nucleotide identity to each other, ≥98.53% to the T. thermophilus strains originating…
View article: Complete Genome Sequence of Thermus thermophilus Strain HB5018, Isolated from Mine Hot Spring in Japan
Complete Genome Sequence of Thermus thermophilus Strain HB5018, Isolated from Mine Hot Spring in Japan Open
We isolated Thermus thermophilus strain HB5018 from Mine Hot Spring in Japan, where the type strain HB8 was isolated nearly half a century ago. The complete genome sequence of HB5018 showed 99.1% average nucleotide identity with HB8, sugge…
View article: The C‐terminal flexible region of branched‐chain polyamine synthase facilitates substrate specificity and catalysis
The C‐terminal flexible region of branched‐chain polyamine synthase facilitates substrate specificity and catalysis Open
Branched‐chain polyamine synthase (BpsA) catalyzes sequential aminopropyl transfer from the donor, decarboxylated S ‐adenosylmethionine (dc SAM ), to the acceptor, linear‐chain polyamine, resulting in the production of a quaternary‐branche…
View article: A Composting System to Decompose Radiocesium Contaminated Baled Grass Silage
A Composting System to Decompose Radiocesium Contaminated Baled Grass Silage Open
Due to the Fukushima Daiichi nuclear power plant accident, a tremendous amount of organic waste (e.g., baled grass silage) contaminated with radioactivity was generated in Tohoku region, northeastern Japan. To establish a safe and efficien…
View article: Active site geometry of a novel aminopropyltransferase for biosynthesis of hyperthermophile‐specific branched‐chain polyamine
Active site geometry of a novel aminopropyltransferase for biosynthesis of hyperthermophile‐specific branched‐chain polyamine Open
Branched‐chain polyamines are found exclusively in thermophilic bacteria and Euryarchaeota and play essential roles in survival at high temperatures. In the present study, kinetic analyses of a branched‐chain polyamine synthase from the hy…
View article: Long and branched polyamines are required for maintenance of the ribosome, tRNA<sup>His</sup> and tRNA<sup>Tyr</sup> in <i>Thermus thermophilus</i> cells at high temperatures
Long and branched polyamines are required for maintenance of the ribosome, tRNA<sup>His</sup> and tRNA<sup>Tyr</sup> in <i>Thermus thermophilus</i> cells at high temperatures Open
Thermus thermophilus is an extremely thermophilic eubacterium that produces various polyamines. Aminopropylagmatine ureohydrolase (SpeB) and SAM decarboxylase‐like protein 1 (SpeD1) are involved in the biosynthesis of spermidine from argin…
View article: Deciphering the Translation Initiation Factor 5A Modification Pathway in Halophilic Archaea
Deciphering the Translation Initiation Factor 5A Modification Pathway in Halophilic Archaea Open
Translation initiation factor 5A (IF5A) is essential and highly conserved in Eukarya (eIF5A) and Archaea (aIF5A). The activity of IF5A requires hypusine, a posttranslational modification synthesized in Eukarya from the polyamine precursor …