Takahiro Higashibata
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View article: Family-Integrated Advance Care Planning for Cancer Patients: A Mixed-Methods Feasibility Study
Family-Integrated Advance Care Planning for Cancer Patients: A Mixed-Methods Feasibility Study Open
The SICG-Fam was delivered by physicians and accepted by patients and family members. However, how physicians consider the family perception of the conversation may mitigate potential patient and family member distress. Future studies shou…
View article: Naldemedine for Opioid-Induced Constipation in Patients With Cancer: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial
Naldemedine for Opioid-Induced Constipation in Patients With Cancer: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial Open
PURPOSE Opioid-induced constipation is the most frequent and non–self-limiting adverse effect of opioid analgesia, reducing adherence and interfering with pain relief. This clinical trial aimed to clarify the preventive effect of naldemedi…
View article: Naldemedine and Magnesium Oxide as First-Line Medications for Opioid-Induced Constipation: A Comparative Database Study in Japanese Patients With Cancer Pain
Naldemedine and Magnesium Oxide as First-Line Medications for Opioid-Induced Constipation: A Comparative Database Study in Japanese Patients With Cancer Pain Open
Introduction Naldemedine and magnesium oxide are common first-line early laxative medications used in the real-world scenario in Japan, for patients with cancer pain who receive opioid prescriptions, as per a nationwide hospital claims dat…
View article: A Nationwide Hospital Claims Database Analysis of Real-World Patterns of Laxative Use for Opioid-Induced Constipation in Japanese Patients with Cancer
A Nationwide Hospital Claims Database Analysis of Real-World Patterns of Laxative Use for Opioid-Induced Constipation in Japanese Patients with Cancer Open
View article: Work Environmental Factors Associated with Compassion Satisfaction and End-of-Life Care Quality Among Nurses in General Wards, Palliative Care Units, and Home Care Settings: A Cross-Sectional Survey
Work Environmental Factors Associated with Compassion Satisfaction and End-of-Life Care Quality Among Nurses in General Wards, Palliative Care Units, and Home Care Settings: A Cross-Sectional Survey Open
View article: Rationale and design of a multicenter, double-blinded, randomized, placebo-controlled trial to investigate the effects of naldemedine on opioid-induced constipation for patients with cancer pain: A study protocol
Rationale and design of a multicenter, double-blinded, randomized, placebo-controlled trial to investigate the effects of naldemedine on opioid-induced constipation for patients with cancer pain: A study protocol Open
jRCT identifier: jRCTs031200397. Registered March 5, 2021, https://rctportal.niph.go.jp/en/detail?trial_id=jRCTs031200397.
View article: Association of a home-based nursing service during chemotherapy with the transfer to home care immediately after the last chemotherapy treatment in patients with advanced cancer
Association of a home-based nursing service during chemotherapy with the transfer to home care immediately after the last chemotherapy treatment in patients with advanced cancer Open
Background The appropriate timing of introducing the home-based nursing service to patients with advanced cancer has not been clarified. This study conducted a retrospective cohort study to investigate the associations of the early utiliza…
View article: Effects of artificial nutrition and hydration on survival in patients with head and neck cancer and esophageal cancer admitted to palliative care units
Effects of artificial nutrition and hydration on survival in patients with head and neck cancer and esophageal cancer admitted to palliative care units Open
View article: Tapentadol Safety and Patient Characteristics Associated with Treatment Discontinuation in Cancer Therapy: A Retrospective Multicentre Study in Japan.
Tapentadol Safety and Patient Characteristics Associated with Treatment Discontinuation in Cancer Therapy: A Retrospective Multicentre Study in Japan. Open
View article: The prevalence of artificially administered nutrition and hydration in different age groups among patients with advanced cancer admitted to palliative care units
The prevalence of artificially administered nutrition and hydration in different age groups among patients with advanced cancer admitted to palliative care units Open
Summary: Background & Aims: The prevalence of artificially administered nutrition and hydration (AANH) in different age groups among patients with advanced cancer remains unknown. The present study investigated the current utilization of A…
View article: C-Reactive Protein and Its Relationship with Pain in Patients with Advanced Cancer Cachexia: Secondary Cross-Sectional Analysis of a Multicenter Prospective Cohort Study
C-Reactive Protein and Its Relationship with Pain in Patients with Advanced Cancer Cachexia: Secondary Cross-Sectional Analysis of a Multicenter Prospective Cohort Study Open
Background: Limited information is available on the relationship between C-reactive protein (CRP) levels and pain in advanced cancer. Objectives: To investigate the relationship between serum levels of CRP and subtypes of pain. Design: A s…
View article: Barriers to inpatient palliative care consultation among patients with newly diagnosed cancer after emergency admission
Barriers to inpatient palliative care consultation among patients with newly diagnosed cancer after emergency admission Open
According to this study, short survival time and no disclosure of cancer diagnosis are potential patient-related barriers to inpatient PC consultation among patients with newly diagnosed cancer after EA.
View article: Associations of smoking status with other lifestyle behaviors are modified by sex and occupational category among urban civil servants in Japan
Associations of smoking status with other lifestyle behaviors are modified by sex and occupational category among urban civil servants in Japan Open
The associations of current smoking with other unhealthy behaviors were modified by sex and occupational category. These results are useful for understanding the health risks among smokers according to sex and occupational category.
View article: A case report of intractable nausea due to zoledronic acid-refractory hypercalcemia treated with denosumab
A case report of intractable nausea due to zoledronic acid-refractory hypercalcemia treated with denosumab Open
【はじめに】ゾレドロン酸抵抗性の高カルシウム血症による難治性悪心が,デノスマブ投与により緩和され生活の質が改善した1例を経験した.【事例】54歳女性,腎盂癌,多発転移.血清カルシウム値上昇と悪心を認めた.複数の制吐薬の使用では症状改善困難でゾレドロン酸を投与したところカルシウム値低下と共に悪心もSTAS-J 3から1に改善した.3回目のゾレドロン酸投与後は補正カルシウム値11.8 mg/dlと抵抗性を示し,悪心の改善は認めずデノスマブを投与した.投与15日後にカルシウム値9…