Takahito Fujimori
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View article: Classification accuracy of pain intensity induced by leg blood flow restriction during walking using machine learning based on electroencephalography
Classification accuracy of pain intensity induced by leg blood flow restriction during walking using machine learning based on electroencephalography Open
Pain assessment in clinical practice largely relies on patient-reported subjectivity. Although previous studies using fMRI and EEG have attempted objective pain evaluation, their focus has been limited to resting conditions. This study aim…
View article: Comparing the osteogenic effects of sputtered titanium- and strontium titanate (STO)-modified polyetheretherketone
Comparing the osteogenic effects of sputtered titanium- and strontium titanate (STO)-modified polyetheretherketone Open
Polyetheretherketone (PEEK) is widely used as an interbody cage due to its elastic modulus closely resembles that of human bone. However, its biological inertness is considered a major weakness, as it cannot directly bond with bone (lack o…
View article: rhBMP-2-loaded hydroxyapatite/beta-tricalcium phosphate microsphere/hydrogel composite promotes bone regeneration in a novel rat femoral nonunion model
rhBMP-2-loaded hydroxyapatite/beta-tricalcium phosphate microsphere/hydrogel composite promotes bone regeneration in a novel rat femoral nonunion model Open
Background Nonunion following fracture treatment remains a significant clinical challenge, adversely affecting the patient’s quality of life and imposing a substantial economic burden. The emergence of bone morphogenetic protein 2 (BMP-2) …
View article: Additional Cover
Additional Cover Open
Cover legend: The cover image is based on the Article Cellular senescence by loss of Men1 in osteoblasts is critical for age‐related osteoporosis by Yuichiro Ukon et al., https://doi.org/10.1111/acel.14254 [Image: see text]
View article: Cellular senescence by loss of <i>Men1</i> in osteoblasts is critical for age‐related osteoporosis
Cellular senescence by loss of <i>Men1</i> in osteoblasts is critical for age‐related osteoporosis Open
Recent evidence suggests an association between age‐related osteoporosis and cellular senescence in the bone; however, the specific bone cells that play a critical role in age‐related osteoporosis and the mechanism remain unknown. Results …
View article: Appropriate pelvic obliquity measurement method in Lenke type 5C adolescent idiopathic scoliosis: a preliminary study
Appropriate pelvic obliquity measurement method in Lenke type 5C adolescent idiopathic scoliosis: a preliminary study Open
Given the asymmetric sacral morphology, SO is more appropriate pelvic parameter than IO to represent the sacral tilt of Lenke 5C AIS, especially when measured using CT images to overcome the poor visibility on PA whole-spine radiographs.
View article: Identification of unapproved orthopedic regenerative medicine: Usefulness of the Act on Safety of Regenerative Medicine
Identification of unapproved orthopedic regenerative medicine: Usefulness of the Act on Safety of Regenerative Medicine Open
View article: A Comparison Between GPT-3.5, GPT-4, and GPT-4V: Can the Large Language Model (ChatGPT) Pass the Japanese Board of Orthopaedic Surgery Examination?
A Comparison Between GPT-3.5, GPT-4, and GPT-4V: Can the Large Language Model (ChatGPT) Pass the Japanese Board of Orthopaedic Surgery Examination? Open
View article: Development of patient-reported outcome for adult spinal deformity: validation study
Development of patient-reported outcome for adult spinal deformity: validation study Open
Adult spinal deformity (ASD) is a complex condition that combines scoliosis, kyphosis, pain, and postoperative range of motion limitation. The lack of a scale that can successfully capture this complex condition is a clinical challenge. We…
View article: Mortality and morbidity among dialysis-dependent patients undergoing spine surgery: Insights from a prospective surgeon-maintained database
Mortality and morbidity among dialysis-dependent patients undergoing spine surgery: Insights from a prospective surgeon-maintained database Open
View article: Bimodal artificial intelligence using TabNet for differentiating spinal cord tumors—Integration of patient background information and images
Bimodal artificial intelligence using TabNet for differentiating spinal cord tumors—Integration of patient background information and images Open
We proposed a bimodal artificial intelligence that integrates patient information with images to diagnose spinal cord tumors. Our model combines TabNet, a state-of-the-art deep learning model for tabular data for patient information, and a…
View article: Cellular senescence by loss of Men1 in osteoblasts is critical for age-related osteoporosis
Cellular senescence by loss of Men1 in osteoblasts is critical for age-related osteoporosis Open
Recent evidence suggests an association between age-related osteoporosis and cellular senescence in the bone; however, the specific bone cells that play a critical role in age-related osteoporosis and the mechanism remain unknown. Results …
View article: Review of Basic Research about Ossification of the Spinal Ligaments Focusing on Animal Models
Review of Basic Research about Ossification of the Spinal Ligaments Focusing on Animal Models Open
Ossification of the posterior longitudinal ligament (OPLL) is a heterotopic ossification that may cause spinal cord compression. With the recent development of computed tomography (CT) imaging, it is known that patients with OPLL often hav…
View article: Comparison of anterior spinal fusion and posterior cervical foraminotomy for cervical spondylotic radiculopathy in terms of postoperative recovery of upper extremity motor deficits
Comparison of anterior spinal fusion and posterior cervical foraminotomy for cervical spondylotic radiculopathy in terms of postoperative recovery of upper extremity motor deficits Open
View article: Primary thoracic spine surgery for degenerative diseases: Exploring risk factors for surgery-related complications and patient characteristics in those also undergoing cervical and/or lumbar spine surgery
Primary thoracic spine surgery for degenerative diseases: Exploring risk factors for surgery-related complications and patient characteristics in those also undergoing cervical and/or lumbar spine surgery Open
View article: Development of artificial intelligence for automated measurement of cervical lordosis on lateral radiographs
Development of artificial intelligence for automated measurement of cervical lordosis on lateral radiographs Open
View article: Prostaglandin EP4 Selective Agonist AKDS001 Enhances New Bone Formation by Minimodeling in a Rat Heterotopic Xenograft Model of Human Bone
Prostaglandin EP4 Selective Agonist AKDS001 Enhances New Bone Formation by Minimodeling in a Rat Heterotopic Xenograft Model of Human Bone Open
To enhance bone regeneration, the use of bone morphogenetic protein (BMP)-2 is an attractive option. Unfortunately, the dose-dependent side effects prevent its widespread use. Therefore, a novel osteogenic agent using a different mechanism…
View article: Measurement Accuracy of Artificial Intelligence in the Form of Convolutional Neural Networks for Cervical Lordosis on Lateral Radiographs
Measurement Accuracy of Artificial Intelligence in the Form of Convolutional Neural Networks for Cervical Lordosis on Lateral Radiographs Open
Although cervical alignment is important for evaluating spine disorders, manual measurement is time-consuming and burdensome. We aimed to validate the usefulness of artificial intelligence (AI) in the form of convolutional neural networks …
View article: Epidemiology of symptomatic ossification of the posterior longitudinal ligament: a nationwide registry survey
Epidemiology of symptomatic ossification of the posterior longitudinal ligament: a nationwide registry survey Open
According to registry data, the prevalence of symptomatic OPLL was less than one-hundredth of that of radiographically detected OPLL. This indicates that most cases of radiographically detectable OPLL may be asymptomatic.
View article: Retrospective Cohort Study Showing Clinical Equivalence of Microendoscopic Laminotomy to Open Fenestration for Patients with Lumbar Spinal Stenosis
Retrospective Cohort Study Showing Clinical Equivalence of Microendoscopic Laminotomy to Open Fenestration for Patients with Lumbar Spinal Stenosis Open
Objective Despite the popularity of microendoscopic disectomy, there is currently insufficient studies about microendoscopic laminotomy (MEL) for lumbar spinal stenosis. The purpose of this study was to compare the clinical and radiographi…
View article: Does Atherosclerosis Have Negative Impacts on Early Adjacent Segment Degeneration After Posterior Lumbar Interbody Fusion?
Does Atherosclerosis Have Negative Impacts on Early Adjacent Segment Degeneration After Posterior Lumbar Interbody Fusion? Open
Study Design: Retrospective study. Objective: To examine whether atherosclerosis has negative impacts on early adjacent segment degeneration (ASD) after posterior lumbar interbody fusion using traditional trajectory pedicle screw fixation …
View article: Abdominal Aortic Calcification Is a Significant Poor Prognostic Factor for Clinical Outcomes After Decompressive Laminotomy for Lumbar Spinal Canal Stenosis
Abdominal Aortic Calcification Is a Significant Poor Prognostic Factor for Clinical Outcomes After Decompressive Laminotomy for Lumbar Spinal Canal Stenosis Open
Study Design: Retrospective study. Objective: To examine whether the presence of chronic kidney disease (CKD) or advanced abdominal aortic calcification (AAC) negatively affects clinical outcomes after decompression surgery for lumbar spin…
View article: Severe cervical flexion myelopathy with long tract signs: a case report and a review of literature
Severe cervical flexion myelopathy with long tract signs: a case report and a review of literature Open
View article: Factors associated with patient satisfaction for PLIF: Patient satisfaction analysis
Factors associated with patient satisfaction for PLIF: Patient satisfaction analysis Open
High satisfaction rate to PLIF and significant correlation between patient- and surgeon-based surgical outcomes were detected. Postoperative permanent motor loss and multiple revision surgery were the major factors related to a negative re…
View article: Does Transforaminal Lumbar Interbody Fusion Have Advantages over Posterolateral Lumbar Fusion for Degenerative Spondylolisthesis?
Does Transforaminal Lumbar Interbody Fusion Have Advantages over Posterolateral Lumbar Fusion for Degenerative Spondylolisthesis? Open
The author regrets an error in the Conclusion of the above article, published in the Global Spine Journal, Volume 5, Number 2, 2015 (DOI: 10.1055/s-0034-1396432). The word “reduction” was inadvertently omitted. The corrected Conclusion app…
View article: Sacroiliac joint motion in patients with degenerative lumbar spine disorders
Sacroiliac joint motion in patients with degenerative lumbar spine disorders Open
OBJECT Usually additional anchors into the ilium are necessary in long fusion to the sacrum for degenerative lumbar spine disorders (DLSDs), especially for adult spine deformity. Although the use of anchors is becoming quite common, surgeo…
View article: The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung
The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung Open
View article: Comparison of the Japanese Orthopaedic Association Score and the Japanese Orthopaedic Association Cervical Myelopathy Evaluation Questionnaire Scores: Time-Dependent Changes in Patients with Cervical Spondylotic Myelopathy and Posterior Longitudinal Ligament
Comparison of the Japanese Orthopaedic Association Score and the Japanese Orthopaedic Association Cervical Myelopathy Evaluation Questionnaire Scores: Time-Dependent Changes in Patients with Cervical Spondylotic Myelopathy and Posterior Longitudinal Ligament Open
Scores for upper- and lower-extremity function on the JOACMEQ correlated well with JOA scores. Because the JOACMEQ can also assess cervical spine function and quality of life, factors that cannot be assessed by the JOA score alone, the JOA…