Explanipedia

Medial plica is associated with progression of medial meniscus extrusion in middle-aged persons with Kellgren–Lawrence grade 0: data from the osteoarthritis initiative Open

S. Hada, Haruka Kaneko, Takako Aoki, Shuko Nojiri, Martin Englund , et al. · 2025

Bone marrow lesion coexisted with subchondral bone attrition and/or subchondral bone cyst is associated with knee pain in knee osteoarthritis regardless of cartilage lesion: the Bunkyo health study Open

Jun Tomura, Haruka Kaneko, Arepati Adili, Takako Aoki, Lizu Liu , et al. · 2025

BML coexistent with SBA and/or SBC, but not BML without the coexistence, was associated with knee pain in the elderly with knee OA regardless of the presence or absence of cartilage lesion.

Medial meniscus extrusion is invariably observed and consistent with tibial osteophyte width in elderly populations: The Bunkyo Health Study Open

Yoshifumi Negishi, Haruka Kaneko, Takako Aoki, Lizu Liu, Arepati Adili , et al. · 2023

We reported that the full-length width of medial tibial osteophytes comprising cartilage and bone parts correlates with medial meniscus extrusion (MME) in early-stage knee osteoarthritis (OA). However, no data exist on the prevalence of MM…

Anterior meniscus extrusion is associated with anterior tibial osteophyte width in knee osteoarthritis – The Bunkyo Health Study Open

Arepati Adili, Haruka Kaneko, Takako Aoki, Lizu Liu, Yoshifumi Negishi , et al. · 2023

Variant spectrum of PIEZO1 and KCNN4 in Japanese patients with dehydrated hereditary stomatocytosis Open

Erina Nakahara, Keiko Shimojima Yamamoto, Hiromi Ogura, Takako Aoki, Taiju Utsugisawa , et al. · 2023

Hereditary stomatocytosis (HSt) is a type of congenital hemolytic anemia caused by abnormally increased cation permeability of erythrocyte membranes. Dehydrated HSt (DHSt) is the most common subtype of HSt and is diagnosed based on clinica…

Medial meniscus extrusion is directly correlated with medial tibial osteophyte in patients received reconstruction surgery for anterior cruciate ligament injury: A longitudinal study Open

S. Hada, Haruka Kaneko, Lizu Liu, Takako Aoki, Tomohiro Takamura , et al. · 2022

MME and medial tibial osteophyte were simultaneously increased after surgery. In addition to close correlation between MME and medial tibial osteophyte width, changes of MME and medial tibial osteophyte width before and after surgery were …

Variant spectrum of PIEZO1 and KCNN4 in Japanese patients with dehydrated hereditary stomatocytosis Open

Keiko Shimojima Yamamoto, Erina Nakahara, Hiromi Ogura, Takako Aoki, Taiju Utsugisawa , et al. · 2022

Hereditary stomatocytosis (HSt) is a type of congenital hemolytic anemia caused by abnormally increased cation permeability of erythrocyte membranes. Dehydrated HSt (DHSt) is the most common subtype of HSt and is diagnosed based on clinica…

Medial meniscus extrusion is invariably observed and consistent with tibial osteophyte width in elderly populations: The Bunkyo Health Study Open

Yoshifumi Negishi, Haruka Kaneko, Takako Aoki, Lizu Liu, Arepati Adili , et al. · 2022

We reported that full-length width of medial tibial osteophyte composed of cartilage and bone parts is directly correlated with medial meniscus extrusion (MME) in early-stage knee osteoarthritis (OA). However, no data are available for MME…

Association of autosomal‐recessive‐type distal renal tubular acidosis and Glanzmann thrombasthenia as a consequence of runs of homozygosity Open

Keiko Aso, Takehiko Soutome, Mari Satoh, Takako Aoki, Hiromi Ogura , et al. · 2022

We report the case of a Filipino girl with autosomal‐recessive‐type distal renal tubular acidosis and Glanzmann thrombasthenia caused by homozygous variants in the genes SLC4A1 and ITGA2B within the long homozygous DNA region on chromosome…

Clinical and genetic diagnosis of thirteen Japanese patients with hereditary spherocytosis Open

Keiko Shimojima Yamamoto, Taiju Utshigisawa, Hiromi Ogura, Takako Aoki, Takahiro Kawakami , et al. · 2022

Hereditary spherocytosis is the most frequent cause of hereditary hemolytic anemia and is classified into five subtypes (SPH1-5) according to OMIM. Because the clinical and laboratory features of patients with SPH1-5 are variable, it is di…

Medial meniscus extrusion is a determinant factor for the gait speed among MRI-detected structural alterations of knee osteoarthritis Open

Hitoshi Arita, Haruka Kaneko, Masayoshi Ishibashi, R. Sadatsuki, Lizu Liu , et al. · 2021

Motility of healthy elderlies with knee pain are impaired in compasiron to that of those without knee pain -the bunkyo health study Open

S. Wakana, Haruka Kaneko, Y. Negishi, L. Liu, Takako Aoki , et al. · 2021

Novel COL4A1 mutations identified in infants with congenital hemolytic anemia in association with brain malformations Open

Hiromi Ogura, Shouichi Ohga, Takako Aoki, Taiju Utsugisawa, Hidehiro Takahashi , et al. · 2020

Genetic causes of undiagnosed hemolytic anemia in nineteen patients were analyzed by whole-exome sequencing, and novel COL4A1 variants were identified in four patients (21%). All patients were complicated with congenital malformations of t…

Molecular Profiles of Breast Cancer in a Single Institution Open

Takako Kamio, Hidenori Kamio, Takako Aoki, Yumiko Ondo, T. Uchiyama , et al. · 2020

As hypermutated breast cancers are more likely to benefit from certain anti-cancer treatment strategies, molecular profiling can be used as a biomarker.

Osteophyte formation is associated with synovitis in osteoarthritis -Thebunkyo health study Open

A. Arepati, Muneaki Ishijima, Hiroba Kanako, Takako Aoki, L. Liu , et al. · 2020

Vitamin D levels are inversely associated with osteophyte formation in elderly women, but not men - a population-based cohort study “The Bunkyo Health Study” Open

L. Liu, Muneaki Ishijima, Haruka Kaneko, Takako Aoki, Y. Negishi , et al. · 2020

Medial meniscus extrusion is a risk factor for knee pain in elderlies who didn’t need clinical care on their knee - the bunkyo healthy study Open

Hui Huang, Muneaki Ishijima, Haruka Kaneko, L. Liu, Takako Aoki , et al. · 2020

Meniscal degeneration in medial meniscus is associated with medial meniscal extrusion in elderly populations -the bunkyo health study Open

Takako Aoki, Muneaki Ishijima, Haruka Kaneko, L. Liu, Y. Negishi , et al. · 2020

PS1202 DIFFERENTIAL DIAGNOSIS OF CONGENITAL HEMOLYTIC ANEMIA OF NEONATES AND INFANTS IN JAPAN Open

H Ogura, Taiju Utsugisawa, Takako Aoki, Aya Kinoshita, Yuruko OKAMOTO , et al. · 2019

Background: As a reference center, we analyze erythrocyte membranes, enzymes, and hemoglobin for congenital hemolytic anemia (CHA) in cases that are not diagnosed using ordinary laboratory examinations, and we introduce genetic testing usi…

PS1205 META‐ANALYSIS USING DATA OF RED BLOOD CELL ENZYME ASSAY AND PROTEOME IN PATIENTS WITH DIAMOND‐BLACKFAN ANEMIA Open

Taiju Utsugisawa, T. Uchiyama, Takako Aoki, A. Kinoshita, Yasuyuki Okamoto , et al. · 2019

Background: Diamond‐Blackfan anemia (DBA) is a form of congenital bone marrow failure syndrome, which is characterized by RBC aplasia with varied malformation in infants. Elevated enzymatic activity of adenosine deaminase (ADA) is known to…

The degeneration of medial meniscus in meniscal body and posterior horn shows a greater change than that in anterior horn according to the severity of medial meniscus extrusion in early- to primary-stage knee osteoarthritis Open

S. Hada, Muneaki Ishijima, Haruka Kaneko, L. Lizu, H. Arita , et al. · 2019

Association between medial meniscus extrusion (MME) and region of meniscal tear in middle aged and elderly population cohort -a sportology core study2- Open

Takako Aoki, Muneaki Ishijima, Haruka Kaneko, Y. Negishi, L. Liu , et al. · 2019

Association between the osteophyte width, medial meniscus extrusion (mme), and meniscal tear in middle aged and elderly population cohort-a sportology core study2- Open

Y. Negishi, Muneaki Ishijima, Haruka Kaneko, Takako Aoki, L. Liu , et al. · 2019

Osteophytes formation processes in early stage knee osteoarthritis in human Open

Haruka Kaneko, A. Arepati, H. Arita, M. Momoeda, Y. Negishi , et al. · 2019

Medial meniscus extrusion is associated with the gait speed among the MRI-detected pathophysiologies of the knee joint in patients with knee osteoarthritis Open

H. Arita, Muneaki Ishijima, Haruka Kaneko, M. Ishibashi, M. Kinoshita , et al. · 2019

Association between vitamin d status and mineralization disorder of osteophyte in middle aged and elderly population with kellgren-lawrence grade 2 of knee osteoarthritis-a sportology core study 2 Open

M. Momoeda, Haruka Kaneko, L. Liu, S. Hada, H. Arita , et al. · 2019

KLF1 mutation E325K induces cell cycle arrest in erythroid cells differentiated from congenital dyserythropoietic anemia patient-specific induced pluripotent stem cells Open

Hiroshi Kohara, Taiju Utsugisawa, Chika Sakamoto, Lisa Hirose, Yoshie Ogawa , et al. · 2019

Vitamin D status is associated with mineralization of osteophyte in patients with knee osteoarthritis Open

M. Momoeda, Haruka Kaneko, L. Liu, S. Hada, H. Arita , et al. · 2018

SURVEY OF THE STATUS OF INTRAVENOUS IMMUNOGLOBULIN (IVIG) PRODUCTS: TRANSITION IN RECENT YEARS AT TOKYO WOMEN'S MEDICAL UNIVERSITY HOSPITAL Open

Kyoko Nakabayashi, Kazuki Matsuda, Hirohito Kobayashi, Shingo Ono, Takuya Iwasaki , et al. · 2018

血液製剤やアルブミン製剤はガイドラインで適正使用基準が明確に示されているが静注用免疫グロブリン（IVIG）に関しては，未だ明確な使用基準が設定されていない．国内血漿由来のIVIGの総供給量は2010年度から2015年度の6年間で3,800kgから4,600kgと著明な増加が認められた．一方当院におけるIVIG総使用量は2010年から2015年の6年間の平均で24.1kgであった．IVIG使用量の多い上位4診療科は神経内科，泌尿器科，消化器科，血液内科でそれぞれ全使用量の約3…

Mobility and Muscular Power of Lower Limbs in Elderlies with Radiographic Moderate Knee Osteoarthritis (OA) but No Knee Pain was Inferior to That of Those in Elderlies with Radiographic Primary Knee Osteoarthritis (OA) but No Knee Pain - A Population-Based Cohort Study “Sportology Core Study 2” Open

Lizu Liu, Muneaki Ishijima, Haruka Kaneko, Takako Aoki, Yoshifumi Tamura , et al. · 2018

Purpose: Pain is the major reason why individuals seek medical attention from early-through endstage knee OA, and is also a major determinant for the loss of joint function. The prevalence of knee osteoarthritis (OA) in women in eighties i…

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