Takako Nakamura
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View article: A comprehensive approach for identifying filaggrin mutations and copy number variants by long-read sequencing
A comprehensive approach for identifying filaggrin mutations and copy number variants by long-read sequencing Open
Filaggrin (FLG) is essential for skin barrier function, but has highly diverse and complex mutations linked to various allergic and dermatological diseases. Current genotyping methods often fail to capture the full range of FLG variants, e…
View article: Gut microbiota of one-and-a-half-year-old food-allergic and healthy children
Gut microbiota of one-and-a-half-year-old food-allergic and healthy children Open
The gut microbiota of food-allergic children has a higher abundance of bacteria involved in intestinal inflammation and a lower abundance of bacteria involved in immune tolerance than that of healthy children. This dysbiosis may also be as…
View article: 中間由紀子・内田和義編著『戦後日本の生活改善普及事業―「考える農民」の育成と農村の民主化―』
中間由紀子・内田和義編著『戦後日本の生活改善普及事業―「考える農民」の育成と農村の民主化―』 Open
View article: Suitable electrochemical deposition conditions to produce Fe-doped Ni hydroxide electrocatalyst for oxygen evolution reactions
Suitable electrochemical deposition conditions to produce Fe-doped Ni hydroxide electrocatalyst for oxygen evolution reactions Open
Massive H2 fuel production by water electrolysis is an essential technology for a future sustainable society. In this study, we report a simple electrochemical deposition (ED) method to produce highly active Fe-doped Ni hydroxide electroca…
View article: A genome-wide association study for allergen component sensitizations identifies allergen component–specific and allergen protein group–specific associations
A genome-wide association study for allergen component sensitizations identifies allergen component–specific and allergen protein group–specific associations Open
Our data provide the first demonstration of genetic risk for allergen component sensitization and show that this genetic risk is related to immune response genes including immunoglobulin heavy-chain variable gene and HLA.
View article: Methylthioacetic acid, a derivative of aroma compounds from <i>Cucumis melo</i> var. <i>conomon</i> dose-dependently triggers differentiation and apoptosis of RCM-1 human colorectal cancer cells
Methylthioacetic acid, a derivative of aroma compounds from <i>Cucumis melo</i> var. <i>conomon</i> dose-dependently triggers differentiation and apoptosis of RCM-1 human colorectal cancer cells Open
Methylthioacetic acid (MTA) is an acid-hydrolyzed derivative of a natural aroma compound, methylthioacetic acid ethyl ester isolated from Cucumis melo var. conomon (Katsura-uri, Japanese Picking Melon), and induces a villiform-like structu…
View article: Surface and Interface Functionalization by Surface Chemical Modification and Nanocoating Technology and Their Application to Joining of Dissimilar Materials
Surface and Interface Functionalization by Surface Chemical Modification and Nanocoating Technology and Their Application to Joining of Dissimilar Materials Open
View article: <scp>Cat‐Ear‐Line</scp>: A Sonographic Sign of Cortical Development?
<span>Cat‐Ear‐Line</span>: A Sonographic Sign of Cortical Development? Open
Objectives Diagonal echogenic lines outside the lateral ventricle have often been observed in the anterior coronal planes of the normal fetal brain by neurosonography. We have observed abnormal shapes of these echogenic lines in cases of m…
View article: Fabrication of multi-layer graphene by repeated transfer
Fabrication of multi-layer graphene by repeated transfer Open
Multi-layer graphene was formed by repeated transfer onto a silicon oxide substrate, and changes in its doping characteristics were observed. The structure of multi-layer graphene was investigated in comparison with pyrolytic graphite with…
View article: RETRACTED ARTICLE: Nationwide distribution of Kyo-yasai (heirloom vegetables in Kyoto) and the advantages of traditional farming methods with importance of ‘Syun’: a case of mizuna
RETRACTED ARTICLE: Nationwide distribution of Kyo-yasai (heirloom vegetables in Kyoto) and the advantages of traditional farming methods with importance of ‘Syun’: a case of mizuna Open
This study aimed to review the farming activity and the administrative measure to successfully increase the distribution of heirloom vegetable "mizuna" nationwide by examining the paradigm shift in the use of its young less-branched form f…
View article: Behavior and possible function of <i>Arabidopsis</i> BES1/BZR1 homolog 2 in brassinosteroid signaling
Behavior and possible function of <i>Arabidopsis</i> BES1/BZR1 homolog 2 in brassinosteroid signaling Open
Two key transcription factors (TFs) in brassinosteroid (BR) signaling BRASSINOSTEROID INSENSITIVE 1-EMS-SUPPRESSOR 1 (BES1) and BRASSINAZOLE RESISTANT 1 (BZR1), belong to a small family with four BES1/BZR1 homologs (BEH1-4). To date, in co…
View article: Classification of Southeast Asian mints (<i>Mentha</i> spp.) based on simple sequence repeat markers
Classification of Southeast Asian mints (<i>Mentha</i> spp.) based on simple sequence repeat markers Open
Mentha is a complex genus encompassing many species as a consequence of their interspecific hybridization and polyploidy. Southeast Asian mints have been poorly distinguished though they are widely used for culinary and medical purp…
View article: Clinical Validation of Fetal cfDNA Analysis Using Rolling-Circle-Replication and Imaging Technology in Osaka (CRITO Study)
Clinical Validation of Fetal cfDNA Analysis Using Rolling-Circle-Replication and Imaging Technology in Osaka (CRITO Study) Open
Background: Noninvasive prenatal genetic testing (NIPT) has been adopted as the first choice for aneuploidy screening. The purposes of this study were to investigate the accuracy of Vanadis® NIPT (hereafter CRITO-NIPT) in order to gain a d…
View article: Neurosonographic Approach to Malformations of Cortical Development
Neurosonographic Approach to Malformations of Cortical Development Open
View article: We Produce the Exchange of Mind More between Urban and Rural Areas, and Let's Express “Green-Tourism” into Internationalization
We Produce the Exchange of Mind More between Urban and Rural Areas, and Let's Express “Green-Tourism” into Internationalization Open
View article: Development of Next-Generation Communication Components by Photoreaction Process
Development of Next-Generation Communication Components by Photoreaction Process Open
View article: Questionnaire Survey of Pharmacy Students regarding Long-term In-hospital Practical Training: 8 Years of Changes
Questionnaire Survey of Pharmacy Students regarding Long-term In-hospital Practical Training: 8 Years of Changes Open
In 2010, the in-hospital practical training period for pharmacy students was extended from 4 to 11 weeks. We have conducted questionnaire surveys of these students every year with the aim of reviewing the quality of training by conduction …
View article: Evaluation of the Usefulness of Postoperative Analgesic Solution Preparation by Pharmacists in the Surgical Department
Evaluation of the Usefulness of Postoperative Analgesic Solution Preparation by Pharmacists in the Surgical Department Open
Pharmacists began preparing drug solutions intraoperatively for postoperative analgesia in the Department of Surgery at Chiba University Hospital from May 2014. To verify the usefulness of pharmacists preparing these drug solutions, we con…
View article: Usability assessment of drug-linking laboratory data listed on prescriptions for outpatients of chiba university hospital
Usability assessment of drug-linking laboratory data listed on prescriptions for outpatients of chiba university hospital Open
View article: Intentions and Features at the Time of Starting Farmer Inn Business: Comparing Before Deregulation and After the Children & Agricultural Communities Interaction Project
Intentions and Features at the Time of Starting Farmer Inn Business: Comparing Before Deregulation and After the Children & Agricultural Communities Interaction Project Open
Recently, farmer inns have been increasing in many rural areas in Japan. We hypothesize that this could be due to their deregulation in 2003, and the Children & Agricultural Communities Interaction Project (CACIP) in 2008. This study analy…
View article: Analysis of patients’ request to switch from a generic drug to the original drug in external prescriptions
Analysis of patients’ request to switch from a generic drug to the original drug in external prescriptions Open
View article: Neoantigen prediction in human breast cancer using RNA sequencing data
Neoantigen prediction in human breast cancer using RNA sequencing data Open
Neoantigens have attracted attention as biomarkers or therapeutic targets. However, accurate prediction of neoantigens is still challenging, especially in terms of its accuracy and cost. Variant detection using RNA sequencing (RNA‐seq) dat…
View article: Chemical and molecular bases of dome formation in human colorectal cancer cells mediated by sulphur compounds from <i>Cucumis melo</i> var. <i>conomon</i>
Chemical and molecular bases of dome formation in human colorectal cancer cells mediated by sulphur compounds from <i>Cucumis melo</i> var. <i>conomon</i> Open
Colorectal cancer was the third most commonly diagnosed malignant tumor and the fourth leading cause of cancer deaths worldwide in 2012. A human colorectal cancer cell line, RCM‐1, was established from a colon cancer tissue diagnosed as a …
View article: Contribution of <i>Katsura-uri</i> (Japan’s Heirloom Pickling Melon, <i>Cucumis melo</i> var. <i>conomon</i>) at the Completely Ripe Stage to Diabetes Control
Contribution of <i>Katsura-uri</i> (Japan’s Heirloom Pickling Melon, <i>Cucumis melo</i> var. <i>conomon</i>) at the Completely Ripe Stage to Diabetes Control Open
The fruit of Katsura-uri (Japan's heirloom pickling melon, Cucumis melo var. conomon) possesses a fruity aroma and moderate sweetness. The fruit juice has potential to minimize human postprandial blood glucose levels. This study provides i…
View article: Association between the NOS2 pentanucleotide repeat polymorphism and risk of postoperative recurrence of chronic rhinosinusitis with nasal polyps in a Japanese population
Association between the NOS2 pentanucleotide repeat polymorphism and risk of postoperative recurrence of chronic rhinosinusitis with nasal polyps in a Japanese population Open
View article: Early Sonographic Findings for Suspecting de novo Single-gene Mutation
Early Sonographic Findings for Suspecting de novo Single-gene Mutation Open
Introduction: Currently, many obstetrics departments widely use prenatal genetic screening tests in the first trimester, including noninvasive prenatal genetic tests (NIPT), sonographic examination, and combined tests.However, many cases w…
View article: Expression profiles of four <i>BES1</i>/<i>BZR1</i> homologous genes encoding bHLH transcription factors in <i>Arabidopsis</i>
Expression profiles of four <i>BES1</i>/<i>BZR1</i> homologous genes encoding bHLH transcription factors in <i>Arabidopsis</i> Open
Arabidopsis bHLH-type transcription factors-BRASSINOSTEROID INSENSITIVE 1-EMS-SUPPRESSOR 1 (BES1) and BRASSINAZOLE RESISTANT 1 (BZR1)-play key roles in brassinosteroid (BR) signaling. By contrast, the functions of the other four BES…
View article: High-Yield Production of the Major Birch Pollen Allergen Bet v 1 With Allergen Immunogenicity in Nicotiana benthamiana
High-Yield Production of the Major Birch Pollen Allergen Bet v 1 With Allergen Immunogenicity in Nicotiana benthamiana Open
Type I allergy is an immunological disorder triggered by allergens and causes significant health problems. The major allergen of birch pollen is Bet v 1, which belongs to the pathogen-related protein 10 (PR-10) family. Here, we established…
View article: Reconsideration of Regional Agricultural and Forestry Economics toward the Next Generation: New Approaches to Understand Real Activities in the field of Regional Agriculture and Forestry
Reconsideration of Regional Agricultural and Forestry Economics toward the Next Generation: New Approaches to Understand Real Activities in the field of Regional Agriculture and Forestry Open
View article: Additional file 3 of Analysis of patients’ request to switch from a generic drug to the original drug in external prescriptions
Additional file 3 of Analysis of patients’ request to switch from a generic drug to the original drug in external prescriptions Open
Additional file 3: Table S2. Data set of the manuscript