Takamasa Hiraki
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View article: Effectiveness of defibrotide for the treatment of children with sinusoidal obstruction syndrome after hematopoietic stem cell transplantation
Effectiveness of defibrotide for the treatment of children with sinusoidal obstruction syndrome after hematopoietic stem cell transplantation Open
2019年にdefibrotide(DF)が肝類洞閉塞症候群(sinusoidal obstruction syndrome,SOS)に対する治療薬として本邦で承認されたが,小児の報告は少ない。今回,造血細胞移植を行った際にSOSを発症し,当院でDFを投与した症例の解析を後方視的に行った。症例は4例で疾患の内訳は骨髄異形成症候群(X-linked inhibitor of apoptosis protein,XIAP)欠損症,神経芽腫,急性リンパ性白血病各1例であった。発症…
View article: Application of Genome-Wide DNA Methylation Analysis to Differentiate a Case of Radiation-Induced Glioblastoma From Late-Relapsed Medulloblastoma
Application of Genome-Wide DNA Methylation Analysis to Differentiate a Case of Radiation-Induced Glioblastoma From Late-Relapsed Medulloblastoma Open
Recurrent medulloblastoma can be difficult to diagnose with conventional diagnostic methods because other lesions mimic tumor relapse, particularly at later stages. We report 2 cases of medulloblastoma, both of which seemed to develop late…
View article: PATH-25. GENOME-WIDE METHYLATION ANALYSIS CAN SEGREGATE RADIATION-INDUCED GLIOBLASTOMA FROM LATE RECURRENCE OF MEDULLOBLATOMAS
PATH-25. GENOME-WIDE METHYLATION ANALYSIS CAN SEGREGATE RADIATION-INDUCED GLIOBLASTOMA FROM LATE RECURRENCE OF MEDULLOBLATOMAS Open
It could be difficult to diagnose recurrent medulloblastoma with conventional diagnostic tools because other lesions mimic relapse of the tumor from both a morphological and radiological standpoint, particularly when it happens late. We re…
View article: PEDT-07 RECURRENT MEDULLOBLASTOMA 9 YEARS AFTER THE PRIMARY TUMOR
PEDT-07 RECURRENT MEDULLOBLASTOMA 9 YEARS AFTER THE PRIMARY TUMOR Open
Medulloblastoma is one of the most common malignant brain tumors in children. Despite multi-disciplinary treatment for medulloblastoma, including surgery, chemotherapy, and radiation, which have resulted in significant improvement of the p…