Explanipedia

Does wearable neurofeedback training improve memory aptitudes in healthy adults? ––A systematic review and meta-analysis Open

Makoto Hagihara, Reiji Ohkuma, Takamitsu Fujimaki, Masako Tamaki, Mitsuaki Takemi , et al. · 2025

Neurofeedback training (NFT) provides individuals with real-time feedback on their brain activity, enabling voluntary modulation. Interest in NFT for memory enhancement has surpassed the cumulative evidence in healthy adults, especially fo…

Enhanced human sensorimotor integration via self-modulation of the somatosensory activity Open

Seitaro Iwama, Takamasa Ueno, Takamitsu Fujimaki, Junichi Ushiba · 2025

EXPERT CONSENSUS ON ACTIVE TRANSPORT REFRIGERATOR OPERATION IN TRANSFUSION MEDICINE Open

Mitsuo Okubo, Hiroshi Fujita, Yoshinobu Seki, Takamitsu Fujimaki, Tomoko Ishihara , et al. · 2025

10085- BT-4 MEDULLOBLASTOMA WITH INTRATUMORAL HEMORRHAGE Open

Yusuke Yamaki, Tomonari Suzuki, Masaya Sato, Masayoshi Fukuoka, Takuro Ehara , et al. · 2024

INTRODUCTION Medulloblastoma, a malignant pediatric brain tumor, is classified into four molecular subtypes: WNT, SHH, Group 3, and Group 4, according to the 2021 WHO classification. Reports indicate that WNT-type medulloblastomas have a h…

GCT-16. LONG-TERM OUTCOMES AND COMPLICATION MANAGEMENT IN CNS GERM CELL TUMORS: INSIGHTS FROM A PHASE II HISTOPATHOLOGY-STRATIFIED TREATMENT TRIAL Open

Hirokazu Takami, Ryo Nishikawa, Tomonari Suzuki, Kazuhiko Takabatake, Takamitsu Fujimaki , et al. · 2024

BACKGROUND This detailed examination merges outcomes from a Phase II clinical trial targeting central nervous system (CNS) germ cell tumors (GCTs) conducted between 1995 and 2003. It evaluates the impact of histopathologically driven treat…

A Case of Unilateral Facial Spasm With Vulnerable Hearing Function Due to a History of Cisplatin Treatment, Resulting in Intraoperative Hearing Loss Open

A Iwasaki, Masahito Kobayashi, Sachiko Hirata, Kazuhiko Takabatake, Masaki Ujihara , et al. · 2024

A 51-year-old man with a history of cisplatin treatment for a right testicular tumor underwent microvascular decompression for hemifacial spasm. At an early stage in the surgical procedure, the intraoperative auditory brainstem response (A…

Gender Balance Survey of Boards of Directors, Councilors, and Committee Members of Nine Academic Societies related to Neurosurgery in Japan Open

S Shimokawa, Yukiko Enomoto, Kazuko Kamiya, Taketoshi Maehara, Tetsuyoshi Horiuchi , et al. · 2024

Neuroprotective Effects of Artificial Cerebrospinal Fluid: Analysis of Brainstem Auditory–Evoked Potential Monitoring During Microvascular Decompression in 117 Consecutive Patients Open

Masahito Kobayashi, S. Hirata, Takamitsu Fujimaki · 2023

BACKGROUND AND OBJECTIVES: To study the efficacy of irrigation with artificial cerebrospinal fluid (aCSF) for protection of cranial nerves during surgery; the time required for recovery of brainstem auditory–evoked potentials (BAEPs) that …

10249-PEDT-8 CURRENT STATUS AND ISSUES OF PEDIATRIC DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) Open

Tomonari Suzuki, Reina Mizuno, Mitsuaki Shirahata, junihci adachi, Ryo Nishikawa , et al. · 2023

that predominantly occurs in childhood, with a median survival of less than one year. Herein we present a recent case of DIPG and discuss the current status and future challenges. The patient was a 7-year-old boy who complained of tinnitus…

CTNI-72. PHASE II TRIAL OF PATHOLOGY-BASED THREE-GROUP TREATMENT STRATIFICATION FOR PATIENTS WITH CNS GERM CELL TUMORS: A LONG-TERM FOLLOW-UP STUDY Open

Hirokazu Takami Fulvio D'Angelo, Tomonari Suzuki, Kazuhiko Takabatake, Takamitsu Fujimaki, Michinari Okamoto , et al. · 2023

BACKGROUND Phase II clinical trial funded by Ministry of Health, Labour and Welfare from 1995 to 2003 evaluated efficacy of pathology-based three-group treatment stratification for CNS germ cell tumors (GCTs). We here present long-term fol…

Regression of Acoustic Tumor After Chemotherapy for Ovarian Cancer in a Patient With a Breast Cancer Susceptibility Gene 1 (BRCA1) Germline Mutation Open

Anna Takeda, Masahito Kobayashi, Kosei Hasegawa, Takamitsu Fujimaki · 2023

We report the case of an adult woman who developed ovarian cancer during a follow-up for vestibular schwannoma. Volume reduction of the schwannoma was observed after chemotherapy for ovarian cancer. After ovarian cancer had been diagnosed,…

Survey on the Attitudes toward Diversity among the Chiefs of Neurosurgery Departments affiliated with the Japanese Neurosurgical Society Open

Yukiko Enomoto, S Shimokawa, Kazuko Kamiya, Taketoshi Maehara, Tetsuyoshi Horiuchi , et al. · 2023

管理的立場にある日本脳神経外科学会所属医師に働き方, 男性の育児休業, 女性医師に対する意識調査を行った. 対象は診療科長863人で13設問を調査し420人から回答を得た (回収率55.2%). 82%の診療科長は仕事を優先し55%はそのバランスに満足していた. 医師の働き方改革への関心は高いが59%が実施後に医療体制は維持できないと考えていた. 44%が男性の育児休業取得は増えると推定したが, 8.3%のみが育休手当の原資を正答できた. また64%が女性医師の増加は実働率…

PEDT-10 PHASE II TRIAL OF PATHOLOGY-BASED THREE-GROUP TREATMENT STRATIFICATION FOR PATIENTS WITH CNS GERM CELL TUMORS: A LONG-TERM FOLLOW-UP STUDY Open

Hirokazu Takami, Tomonari Suzuki, Kazuhiko Takabatake, Takamitsu Fujimaki, Michinari Okamoto , et al. · 2022

Background Phase II clinical trial funded by Ministry of Health, Labour and Welfare from 1995 to 2003 evaluated efficacy of pathology-based three-group treatment stratification for CNS germ cell tumors (GCTs). We here present long-term fol…

Multiple neuroepithelial cysts of the cerebellopontine angle: Case report and review of the literature Open

Masaki Ujihara, Masahito Kobayashi, Atsushi Sasaki, Keisuke Ishizawa, Sachiko Hirata , et al. · 2022

Questionnaire survey regarding working condition of the members belongs to the Japan Society for Neuro-Oncology (JSNO) by the Gender Equality and Diversity Committee of the JSNO 2021 Open

Takamitsu Fujimaki, Kaoru Tamura, Tatsuya Abe, Akiko Higuchi, Mitsutoshi Nakada , et al. · 2022

PEDT-5 Problem for the guideline of CNS germ cell tumors Open

Hideo Nakamura, Takaaki Yanagisawa, Toshinori Soejima, Hideaki Yokoo, Ryo Nishikawa , et al. · 2021

Primary CNS germ cell tumors (GCTs) are rare neoplasms, therefore, a clinical guideline has not been established so far. While better management has been achieved over recent decades by modifying radiation coverage and selecting appropriat…

The Japan Society for Neuro-Oncology guideline on the diagnosis and treatment of central nervous system germ cell tumors Open

Hideo Nakamura, Hirokazu Takami, Takaaki Yanagisawa, Toshihiro Kumabe, Takamitsu Fujimaki , et al. · 2021

Primary CNS germ cell tumors (GCTs) are rare neoplasms predominantly observed in the pediatric and young adult populations. In line with the hypothesis that the primordial germ cell is the cell-of-origin, histopathological examinations for…

Signal and morphological changes in the endolymph of patients with vestibular schwannoma on non-contrast 3D FLAIR at 3 Tesla Open

Iichiro Osawa, Eito Kozawa, Sayuri Tanaka, Akane Kaizu, Kaiji Inoue , et al. · 2021

Background Non-contrast FLAIR revealed increased signal within the inner ear in patients with vestibular schwannoma, which is generally assumed to occur in the perilymph; however, the majority of previous studies did not differentiate betw…

Effectiveness of spinal cord stimulation for improvement of microcirculation and fixed dystonia in complex regional pain syndrome: A case report Open

Noriyuki Yahagi, Masahito Kobayashi, Kenji Wakiya, Sachiko Hirata, Takamitsu Fujimaki · 2021

Complex Regional Pain Syndrome (CRPS) is a form of chronic pain affecting one arm or leg. Spinal cord stimulation (SCS) is one of the few effective treatments for CRPS. However, it is difficult to objectively determine the appropriate cond…

NCOG-61. A CASE OF LONG TERM SURVIVOR OF DISSEMINATED AND RELAPSED GERMINOMA. EIGHTEEN YEARS OF FOLLOW UP Open

Takamitsu Fujimaki, Akira Matsuno · 2020

Germinomas will respond to first-line treatment in general, but prognoses of disseminated and/or relapsed disease are sometimes poor and detailed course of those patients are not well documented. Here we report one of such cases. PATIENT: …

Prospective, Multicenter Clinical Study of Microvascular Decompression for Hemifacial Spasm Open

Yoshifumi Mizobuchi, Shinji Nagahiro, Akinori Kondo, Kazunori Arita, Isao Date , et al. · 2020

ML-08 THE ROLE OF MAINTENANCE HIGH-DOSE METHOTREXATE CHEMOTHERAPY IN ELDERLY PRIMARY CNS LYMPHOMA PATIENTS Open

Kazuhiko Mishima, Mitsuaki Shirahata, Jun-ichi Adachi, Tomonari Suzuki, Takamitsu Fujimaki , et al. · 2019

BACKGROUND The addition of high-dose methotrexate (HD-MTX)-based chemotherapy to whole brain irradiation (WBRT) has improved the prognosis of primary central nervous system lymphoma (PCNSL). However, the high neurotoxicity rates observed, …

GEN-06 CLINICAL COURSE AFTER TUMOR RECURRENCE OF MGMT HYPERMETHYLATED GLIOBLASTOMA Open

Jun-ichi Adachi, Mitsuaki Shirahata, Tomonari Suzuki, Kazuhiko Mishima, Takamitsu Fujimaki , et al. · 2019

MGMT methylation in glioblastoma is a biomarker for determining treatment responsiveness and predicting prognosis. We analyzed whether there were differences in the prognosis between glioblastoma with MGMT hypermethylation and other gliobl…

PEDT-06 THERAPEUTIC STRATEGY FOR DISSEMINATED PILOCYTIC ASTROCYTOMAS Open

Tomonari Suzuki, Rena Mizuno, Eita Uchida, Mitsuaki Shirahata, Jun-ichi Adachi , et al. · 2019

BACKGROUND Pilocytic astrocytoma is one of the common tumors found during childhood. However, the clinical course of disseminated pilocytic astrocytoma is not clearly known. Here, we present two cases with disseminated pilocytic astrocytom…

SURG-21. STEREOTACTIC BIOPSY FOR DEEP SEATED BRAIN LESIONS USING THE LEKSELL STEREOTACTIC FRAME SYSTEM Open

Takamitsu Fujimaki, Sachiko Hirata, Naruhiko Terano, Kenji Wakiya, Jun-ichi Adachi , et al. · 2019

PURPOSE To evaluate the results of stereotactic biopsies. PATIENTS AND METHODS Fifty-two patients with intraaxial lesions suspected of brain tumor. The locations of lesions includes, 19 deep cerebral white matter, 9 basal ganglia, 10 thala…

A Large Mass Mimicking Calcified Hematoma of the Skull Showing Involvement of Myeloma Cells and a Good Response to Irradiation Open

Takamitsu Fujimaki, Sachiko Hirata, Naruhiko Terano, Kenji Wakiya, Masahito Kobayashi · 2019

Patients with multiple myeloma often show skull bone involvement, although in most cases this is manifested as skull erosion and large masses develop only rarely. Here we report a patient who presented with a large cranial mass mimicking a…

A randomized, double-blind, phase III trial of personalized peptide vaccination for recurrent glioblastoma Open

Yoshitaka Narita, Yoshiki Arakawa, Fumiyuki Yamasaki, Ryo Nishikawa, Tomokazu Aoki , et al. · 2018

This phase III trial met neither the primary nor secondary endpoints.

GERM-20. NEUROENDOSCOPIC BIOPSY OF INTRACRANIAL GERM CELL TUMORS: ACCURACY AND COMPLICATIONS Open

Tomonari Suzuki, Jun-ichi Adachi, Kazuhiko Mishima, Takamitsu Fujimaki, Takaaki Yanagisawa , et al. · 2018

OBJECTIVE: Intracranial germ cell tumors (GCTs) are a heterogeneous group of lesions. It is important to obtain the accurate histological diagnosis since the treatment outcomes can depend on histology. Neuroendoscopic biopsy is a minimally…

GERM-18. RELAPSE PATTERN AND TREATMENT OUTCOME OF RECURRENT CENTRAL NERVOUS SYSTEM GERM CELL TUMORS Open

Takaaki Yanagisawa, Tomonari Suzuki, Kohei Fukuoka, Jun-ichi Adachi, Kazuhiko Mishima , et al. · 2018

BACKGROUND: Central nervous system germ cell tumors (CNS-GCT) are a heterogeneous group of diseases. The management of CNS-GCT remains controversial. Objective: To clarify the relapse pattern and outcome of patients with recurrent CNS-GCT …

Ectopic cerebellar tissue in the occipital bone: a case report Open

Mariko Kawashima, Masahito Kobayashi, Keisuke Ishizawa, Takamitsu Fujimaki · 2017

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