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  4. Takashi Ashikaga

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View article: Clinical outcomes of stent-less percutaneous coronary intervention with intravascular lithotripsy and drug-coated balloon for severely calcified de novo coronary lesions
Clinical outcomes of stent-less percutaneous coronary intervention with intravascular lithotripsy and drug-coated balloon for severely calcified de novo coronary lesions Open
Toru Misawa, Tetsumin Lee, Takashi Ashikaga, Toshihiro Nozato, Masakazu Kaneko , et al. · 2025
View article: Dual-Prep registry: atherectomy devices and intravascUlAr lithotripsy for the PREParation of heavily calcified coronary lesions registry
Dual-Prep registry: atherectomy devices and intravascUlAr lithotripsy for the PREParation of heavily calcified coronary lesions registry Open
Masato Nakamura, Nehiro Kuriyama, Yutaka Tanaka, Seiji Yamazaki, Tomohiro Kawasaki , et al. · 2025
Evaluation of calcified lesions by intravascular imaging has revealed that atherectomy devices have only limited impact. However, subsequent use of coronary intravascular lithotripsy (IVL) may increase treatment effectiveness without incre…
View article: Intravascular Lithotripsy Treatment With In-Stent Underexpansion Followed by Angiography, Optical Coherence Tomography, and Coronary Angioscopy
Intravascular Lithotripsy Treatment With In-Stent Underexpansion Followed by Angiography, Optical Coherence Tomography, and Coronary Angioscopy Open
Kazuki Matsuda, Tetsumin Lee, Takashi Ashikaga, Toshihiro Nozato, Yuta Taomoto , et al. · 2025
This case highlights the potential efficacy of IVL for underexpanded ISR lesions with severe calcification.
View article: Case Report: Drug-coated balloon after intravascular lithotripsy for the treatment of severely calcified de novo coronary artery lesion
Case Report: Drug-coated balloon after intravascular lithotripsy for the treatment of severely calcified de novo coronary artery lesion Open
Toru Misawa, Tetsumin Lee, Takashi Ashikaga, Toshihiro Nozato, Taishi Yonetsu , et al. · 2024
In patients undergoing percutaneous coronary intervention (PCI), severely calcified lesions remain a great challenge even in the drug-eluting stent (DES) era. Intravascular lithotripsy (IVL) is effective for modification of severely calcif…
View article: The impact of novel scoring balloon and cutting balloon after orbital atherectomy on severely calcified coronary lesion as assessed by optical coherence tomography
The impact of novel scoring balloon and cutting balloon after orbital atherectomy on severely calcified coronary lesion as assessed by optical coherence tomography Open
Daigo Kachi, Tetsumin Lee, Mao Terui, Masashi Nagase, Toru Misawa , et al. · 2024
Background Debulking devices are often followed by a scoring or cutting balloon in percutaneous coronary intervention (PCI) for severely calcified lesions. However, there are limited data on balloon preparation after orbital atherectomy (O…
View article: A ruptured coronary artery aneurysm treated by covered stent implantation
A ruptured coronary artery aneurysm treated by covered stent implantation Open
Mao Matsuyama Terui, Takashi Ashikaga, Toshihiro Nozato, Ryoichi Miyazaki · 2024
View article: Excimer LASER coronary atherectomy for ST-segment elevation myocardial infarction: a multicenter retrospective cohort analysis
Excimer LASER coronary atherectomy for ST-segment elevation myocardial infarction: a multicenter retrospective cohort analysis Open
Yuji Matsuda, Taishi Yonetsu, Ken Kurihara, Shigeo Shimizu, Akihiko Matsumura , et al. · 2024
BACKGROUND Excimer laser coronary atherectomy (ELCA) is used for thrombotic culprit lesions in ST-segment elevation myocardial infarction (STEMI), but its efficacy is still unclear. The study objective was to investigate the clinical outco…
View article: The efficacy of excimer laser coronary atherectomy in ST-elevation myocardial infarction: a report from the STELA registry
The efficacy of excimer laser coronary atherectomy in ST-elevation myocardial infarction: a report from the STELA registry Open
Yuji Matsuda, Taishi Yonetsu, Ken Kurihara, Tsunekazu Kakuta, Satoshi Shimizu , et al. · 2023
Backgrounds Previous studies have demonstrated potential effect of excimer laser coronary atherectomy (ELCA) to reduce thrombus burden within the vessel, and ELCA has been used during primary PCI for acute coronary syndrome. Especially, th…
View article: Diagnosis and Prognostic Value of the Underlying Cause of Acute Coronary Syndrome in Optical Coherence Tomography–Guided Emergency Percutaneous Coronary Intervention
Diagnosis and Prognostic Value of the Underlying Cause of Acute Coronary Syndrome in Optical Coherence Tomography–Guided Emergency Percutaneous Coronary Intervention Open
Seita Kondo, Takuya Mizukami, Nobuaki Kobayashi, Kohei Wakabayashi, Hiroyoshi Mori , et al. · 2023
Background The prognostic impact of optical coherence tomography–diagnosed culprit lesion morphology in acute coronary syndrome (ACS) has not been systematically examined in real‐world settings. Methods and Results This investigator‐initia…
View article: Excimer Laser Coronary Angioplasty and Drug-Coated Balloon Treatment for Very Late Stent Thrombosis Due to Neoatherosclerosis as Assessed by Optical Coherence Tomography
Excimer Laser Coronary Angioplasty and Drug-Coated Balloon Treatment for Very Late Stent Thrombosis Due to Neoatherosclerosis as Assessed by Optical Coherence Tomography Open
Daigo Kachi, Tetsumin Lee, Michihito Naito, Kazuki Matsuda, Kodai Sayama , et al. · 2023
View article: Drug‐coated balloon strategy following orbital atherectomy for calcified coronary artery compared with drug‐eluting stent: One‐year outcomes and optical coherence tomography assessment
Drug‐coated balloon strategy following orbital atherectomy for calcified coronary artery compared with drug‐eluting stent: One‐year outcomes and optical coherence tomography assessment Open
Kentaro Mitsui, Tetsumin Lee, Ryoichi Miyazaki, Nobuhiro Hara, Sho Nagamine , et al. · 2023
Background Percutaneous coronary intervention (PCI) for calcified coronary artery remains challenging in the drug‐eluting stent (DES) era. While recent studies reported the efficacy of orbital atherectomy (OA) combined with DES for calcifi…
View article: Predictors of coronary artery injury after orbital atherectomy as assessed by optical coherence tomography
Predictors of coronary artery injury after orbital atherectomy as assessed by optical coherence tomography Open
Tetsumin Lee, Takashi Ashikaga, Toshihiro Nozato, Masakazu Kaneko, Ryoichi Miyazaki , et al. · 2023
View article: Unique features of a foreign body seen after proximal optimisation technique following jailed balloon technique
Unique features of a foreign body seen after proximal optimisation technique following jailed balloon technique Open
Mao Matsuyama Terui, Takashi Ashikaga, Toshihiro Nozato, Ryoichi Miyazaki, Tatsuhiro Nagamine · 2023
View article: Novel Use of Excimer Laser Coronary Angioplasty for the Preparation of the Reverse Wire Technique
Novel Use of Excimer Laser Coronary Angioplasty for the Preparation of the Reverse Wire Technique Open
Ryoichi Miyazaki, Takashi Ashikaga, Tetsumin Lee, Toshihiro Nozato · 2023
Guidewire insertion into the side branches during percutaneous coronary intervention may be difficult, depending on the angle of the side branch and plaque localization. The reverse wire technique (RWT) is an effective wiring method for ma…
View article: Simple algorithm to narrow down the candidates to receive echocardiography in patients with chronic liver disease for suspected pulmonary hypertension
Simple algorithm to narrow down the candidates to receive echocardiography in patients with chronic liver disease for suspected pulmonary hypertension Open
Koji Yamashita, Masayuki Kurosaki, Hiroyuki Nakanishi, Yuki Tanaka, Shun Ishido , et al. · 2022
Aims Portopulmonary hypertension (PoPH) is a subtype of pulmonary arterial hypertension related to portal hypertension. The definitive diagnosis of PoPH is made by invasive right heart catheterization. Alternatively, pulmonary arterial hyp…
View article: Alcohol Consumption Is Associated With Postablation Recurrence but Not Changes in Atrial Substrate in Patients With Atrial Fibrillation: Insight from a High‐Density Mapping Study
Alcohol Consumption Is Associated With Postablation Recurrence but Not Changes in Atrial Substrate in Patients With Atrial Fibrillation: Insight from a High‐Density Mapping Study Open
Yuichiro Sagawa, Yasutoshi Nagata, Naoyuki Miwa, Takanori Yamaguchi, Keita Watanabe , et al. · 2022
Background The association between alcohol consumption, atrial substrate, and outcomes after atrial fibrillation (AF) ablation remains controversial. This study evaluated the impacts of drinking on left atrial substrate and AF recurrence a…
View article: Case Report: Importance of MRI Examination in the Diagnosis and Evaluation of COVID-19 mRNA Vaccination Induced Myocarditis: Our Experience and Literature Review
Case Report: Importance of MRI Examination in the Diagnosis and Evaluation of COVID-19 mRNA Vaccination Induced Myocarditis: Our Experience and Literature Review Open
Keita Watanabe, Takashi Ashikaga, Yasuhiro Maejima, Susumu Tao, Mao Terui , et al. · 2022
Acute myocarditis is a rare but serious complication associated with mRNA-based coronavirus disease 2019 (COVID-19) vaccination. In this article, four COVID-19 mRNA vaccination induced myocarditis cases managed at our tertiary Medical Cent…
View article: β-Blockers Reduced the Target Lesion Revascularization After Percutaneous Coronary Intervention Using an Everolimus-eluting Stent
β-Blockers Reduced the Target Lesion Revascularization After Percutaneous Coronary Intervention Using an Everolimus-eluting Stent Open
T Fujinami, Takashi Ashikaga, Katsuyuki Hoshina, Taro Sasaoka, Ken Kurihara , et al. · 2021
β-Blocker administration reduced ID-TLR after percutaneous coronary intervention using an EES despite the greater comorbid risks and more severe disease lesions.
View article: Impact of the sinus node recovery time after termination of atrial fibrillation during catheter ablation on clinical outcomes in patients with persistent atrial fibrillation
Impact of the sinus node recovery time after termination of atrial fibrillation during catheter ablation on clinical outcomes in patients with persistent atrial fibrillation Open
Keita Watanabe, Yasutoshi Nagata, Giichi Nitta, Shinichiro Okata, Masashi Nagase , et al. · 2021
Background Although long sinus arrest is occasionally observed during atrial fibrillation (AF) catheter ablation when the fibrillation was terminated, its meaning and prognosis have not yet been clearly elucidated. We hypothesized that sin…
View article: Effectiveness and Safety of Direct Oral Anticoagulants vs. Warfarin and Recurrence After Discontinuation in Patients With Acute Venous Thromboembolism in the Real World
Effectiveness and Safety of Direct Oral Anticoagulants vs. Warfarin and Recurrence After Discontinuation in Patients With Acute Venous Thromboembolism in the Real World Open
Nobuhiro Hara, Tetsumin Lee, Toshihiro Nozato, Mao Terui Matsuyama, Shinichiro Okata , et al. · 2021
DOACs may decrease bleeding incidence in patients continuing to receive cancer treatment. In patients with bleeding-related discontinuation of anticoagulation therapy, VTE recurrence may increase. Discontinuation of anticoagulant therapy m…
View article: Direct comparison of bioabsorbable and biodurable polymer everolimus-eluting stent in neointimal stent coverage and in-stent thrombus using high-resolution angioscope
Direct comparison of bioabsorbable and biodurable polymer everolimus-eluting stent in neointimal stent coverage and in-stent thrombus using high-resolution angioscope Open
Yuhei Nojima, Toshiaki Mano, Masami Nishino, Kenichi Fuji, Shigeru Nakamura , et al. · 2021
Background/Introduction Although second-generation drug eluting stent (DES) employing biodurable polymer drastically shortened the duration of dual antiplatelet therapy (DAPT), previous reports raised concerns that switching from DAPT to s…
View article: Long-term prognostic factors of coronary artery disease patients after out-of-hospital cardiac arrest
Long-term prognostic factors of coronary artery disease patients after out-of-hospital cardiac arrest Open
Giichi Nitta, Junji Matsuda, T Lee, Shingo Kato, Y Hada , et al. · 2021
Background The long-term prognosis of survival in patients with out-of-hospital cardiac arrest (OHCA) with coronary artery disease (CAD) remains poor. Methods There were 2391 out-of-hospital cardiac arrest (OHCA) patients transferred to 2 …
View article: Drug-coated balloon versus drug-eluting stent following orbital atherectomy for calcified coronary artery: one-year outcomes of a retrospective cohort study
Drug-coated balloon versus drug-eluting stent following orbital atherectomy for calcified coronary artery: one-year outcomes of a retrospective cohort study Open
Kentaro Mitsui, T Lee, Ryoichi Miyazaki, Nobuhiro Hara, Sho Nagamine , et al. · 2021
Background Percutaneous coronary intervention (PCI) for calcified coronary artery remains challenging in the drug-eluting stent (DES) era. The effectiveness of drug-coated balloons (DCBs) and orbital atherectomy system (OAS) is unknown. Me…
View article: Neurological outcome at 30-day as an estimator of 1-year functional status after out-of-hospital cardiac arrest with post-encephalopathy
Neurological outcome at 30-day as an estimator of 1-year functional status after out-of-hospital cardiac arrest with post-encephalopathy Open
Giichi Nitta, Junji Matsuda, Shingo Kato, Y Hada, Osamu Inaba , et al. · 2021
Background Implantation of implantable cardioverter-defibrillators (ICD) for secondary prevention is fully recommended for those with an estimated survival over 1-year with a good functional status. However, we often face the difficulty to…
View article: Anticoagulant Therapy for Cancer-Associated Venous Thromboembolism after Cancer Remission
Anticoagulant Therapy for Cancer-Associated Venous Thromboembolism after Cancer Remission Open
Nobuhiro Hara, Tetsumin Lee, Kentaro Mitsui, Masashi Nagase, Shinichiro Okata , et al. · 2021
Objectives: To examine the outcomes of anticoagulant therapy for patients with venous thromboembolism (VTE) with active cancer and the outcomes after cancer remission with and without anticoagulant therapy. Materials and Methods:…
View article: Acute Ischemic Mitral Regurgitation Treated by Percutaneous Coronary Intervention after an Accurate Diagnosis on Transesophageal Echocardiography
Acute Ischemic Mitral Regurgitation Treated by Percutaneous Coronary Intervention after an Accurate Diagnosis on Transesophageal Echocardiography Open
Ryoichi Miyazaki, Keita Watanabe, Masakazu Kaneko, Sho Nagamine, Nobuhiro Hara , et al. · 2020
An 80-year-old woman with acute posterolateralmyocardial infarction, cardiogenic shock, and acute heart failure was admitted to our hospital. Transthoracic echocardiography (TTE) showed dysfunction of the left ventricular inferolateral wal…
View article: Prediction of premature ventricular complex origins using artificial intelligence–enabled algorithms
Prediction of premature ventricular complex origins using artificial intelligence–enabled algorithms Open
Tomofumi Nakamura, Yasutoshi Nagata, Giichi Nitta, Shinichiro Okata, Masashi Nagase , et al. · 2020
Artificial intelligence-enabled algorithms that predict the origin of PVCs achieved superior accuracy compared to the electrophysiologists and comparable accuracy to the existing algorithm.
View article: Effect of Endovascular Treatment on Systemic Vascular Resistance in Patients with Lower-Limb Peripheral Artery Disease
Effect of Endovascular Treatment on Systemic Vascular Resistance in Patients with Lower-Limb Peripheral Artery Disease Open
Hidetsugu Nomoto, Toshihiro Nozato, Shu Yamashita, Masahito Suzuki, Tomoyo Sugiyama , et al. · 2020
Objective: Endovascular treatment (EVT) for lower-limb peripheral artery disease patients reduces blood pressure (BP) and improves prognosis. This study retrospectively examined hemodynamics during EVT to clarify the mechanism. M…
View article: Administration of Direct Oral Anticoagulant Immediately after Unfractionated Heparin Bolus for the Treatment of Intermediate–High-Risk Pulmonary Thromboembolism
Administration of Direct Oral Anticoagulant Immediately after Unfractionated Heparin Bolus for the Treatment of Intermediate–High-Risk Pulmonary Thromboembolism Open
Nobuhiro Hara, Keita Watanabe, Ryoichi Miyazaki, Tomofumi Nakamura, Tetsumin Lee , et al. · 2020
Objective: This study aims to evaluate the efficacy and safety of direct oral anticoagulants (DOACs) after unfractionated heparin (UFH) bolus for the treatment of intermediate-high-risk pulmonary embolism. Materials and Methods
View article: Comparison of Neointimal Response between Durable-Polymer Everolimus-Eluting Stent and Bioabsorbable-Polymer Everolimus-Eluting Stent for Severely Calcified Lesions Requiring Rotational Atherectomy
Comparison of Neointimal Response between Durable-Polymer Everolimus-Eluting Stent and Bioabsorbable-Polymer Everolimus-Eluting Stent for Severely Calcified Lesions Requiring Rotational Atherectomy Open
Yuji Matsuda, Takashi Ashikaga, Taro Sasaoka, Yu Hatano, Tomoyuki Umemoto , et al. · 2020
Clinical outcomes after percutaneous coronary intervention (PCI) for severely calcified lesions remain poor. The purpose of this study was to investigate the neointimal response after everolimus-eluting stents (EES) for severely calcified …




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