Takashi Kato
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View article: A randomized controlled trial exploring the effect of placement versus nonplacement of a drainage tube around the cervical anastomosis in McKeown esophagectomy
A randomized controlled trial exploring the effect of placement versus nonplacement of a drainage tube around the cervical anastomosis in McKeown esophagectomy Open
Esophageal cancer has an overall five-year survival rate of < 20%. The McKeown esophagectomy is invasive and carries a high risk of anastomotic leakage. Robust prospective outcome data comparing non-placement versus placement of a cervical…
View article: An end-stage kidney disease patient undergoing dialysis treatment for 50 years with dialysis-related amyloidosis in multiple organs
An end-stage kidney disease patient undergoing dialysis treatment for 50 years with dialysis-related amyloidosis in multiple organs Open
View article: Leptin and inflammatory pathways in the Alzheimer's disease continuum: Implications for glial activation and neuropsychiatric symptoms
Leptin and inflammatory pathways in the Alzheimer's disease continuum: Implications for glial activation and neuropsychiatric symptoms Open
View article: Reversible chemical modifications of graphene oxide for enhanced viral capture and release in water
Reversible chemical modifications of graphene oxide for enhanced viral capture and release in water Open
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View article: Liquid-crystalline nanostructured membranes for CO<sub>2</sub> separation
Liquid-crystalline nanostructured membranes for CO<sub>2</sub> separation Open
Self-organized subnanoporous membranes prepared from ionic liquid-crystalline compounds exhibit CO 2 separation properties in humid conditions.
View article: Nanostructured liquid-crystalline ion conductors based on linear carbonate moieties: effects of oligooxyethylene and alkylene spacers on self-assembled properties and ionic conductivities
Nanostructured liquid-crystalline ion conductors based on linear carbonate moieties: effects of oligooxyethylene and alkylene spacers on self-assembled properties and ionic conductivities Open
Ion-conductive 2D nanostructured liquid crystals containing linear carbonate moieties are developed. The complexes of these materials with lithium salts may have potential as self-assembled electrolytes in lithium-ion batteries.
View article: Development of Seismic Isolation Fail-Safe Structure Against Huge Earthquakes
Development of Seismic Isolation Fail-Safe Structure Against Huge Earthquakes Open
View article: Degradation of a Wholly Aromatic Main-Chain Thermotropic Liquid-Crystalline Polymer Mediated by Superbases
Degradation of a Wholly Aromatic Main-Chain Thermotropic Liquid-Crystalline Polymer Mediated by Superbases Open
Plastic circular economy needs to be established to solve environmental issues related to plastic waste. Superengineering plastics such as liquid-crystalline (LC) polymers exhibit excellent thermal and mechanical properties, resulting in p…
View article: Monodisperse nanosheet mesophases
Monodisperse nanosheet mesophases Open
Self-assemblies of anisotropic colloidal particles into colloidal liquid crystals and well-defined superlattices are of great interest for hierarchical nanofabrications that are applicable for various functional materials. Inorganic nanosh…
View article: A randomized controlled trial exploring the effect of placement versus nonplacement of a drainage tube around the cervical anastomosis in McKeown esophagectomy
A randomized controlled trial exploring the effect of placement versus nonplacement of a drainage tube around the cervical anastomosis in McKeown esophagectomy Open
Purpose Esophageal cancer has an overall five-year survival rate of < 20%. The McKeown esophagectomy is invasive and carries a high risk of anastomotic leakage. Robust prospective outcome data comparing non-placement versus placement of a …
View article: Electrochemical Detection of Selective Anion Transport through Subnanopores in Liquid-Crystalline Water Treatment Membranes
Electrochemical Detection of Selective Anion Transport through Subnanopores in Liquid-Crystalline Water Treatment Membranes Open
The anion-selective transport through subnanoporous liquid-crystalline (LC) water treatment membranes was quantitatively detected by the deposition and electrochemical analysis of the LC membrane on the GaN electrode. The time course of th…
View article: A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages
A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages Open
Cholera toxin (CT), a bacterial exotoxin composed of one A subunit (CTA) and five B subunits (CTB), functions as an immune adjuvant. CTB can induce production of interleukin-1β (IL-1β), a proinflammatory cytokine, in synergy with a lipopol…
View article: A novel PET probe to selectively image heat shock protein 90α/β isoforms in the brain
A novel PET probe to selectively image heat shock protein 90α/β isoforms in the brain Open
Background Heat shock proteins (HSPs) are present throughout the brain. They function as molecular chaperones, meaning they help with the folding and unfolding of large protein complexes. These chaperones are vital in the development of ne…
View article: ASO Visual Abstract: Impact of Tumor Size on Survival Outcome in Esophageal Squamous Cell Carcinoma After Esophagectomy Following Neoadjuvant Chemotherapy
ASO Visual Abstract: Impact of Tumor Size on Survival Outcome in Esophageal Squamous Cell Carcinoma After Esophagectomy Following Neoadjuvant Chemotherapy Open
View article: Aquatic Functional Liquid Crystals: Design, Functionalization, and Molecular Simulation (Adv. Sci. 8/2024)
Aquatic Functional Liquid Crystals: Design, Functionalization, and Molecular Simulation (Adv. Sci. 8/2024) Open
Aquatic Functional Liquid Crystals In article number 2306529, Takashi Kato, Junya Uchida, Yoshiki Ishii, and Go Watanabe highlight new aspects of aquatic functional liquid‐crystalline (LC) materials, i.e., subnano‐ and nano‐porous membrane…
View article: A Case of Esophageal Cancer Arising within a Killian-Jamieson Diverticulum
A Case of Esophageal Cancer Arising within a Killian-Jamieson Diverticulum Open
症例は65歳の男性で,他院のスクリーニング検査で多発食道癌を指摘され,そのうちの1病変は食道憩室内に認めた.CTでは甲状腺左葉背側に囊胞性腫瘤様の憩室を認め,頸部食道左側に突出していることからKillian-Jamieson憩室(以下,K-J憩室と略記)と診断し,多発食道癌に対し胸腔鏡下食道亜全摘術(二領域郭清),胸骨後経路再建術を施行した.咽頭食道憩室としてはZenker憩室が一般的であるが,本疾患の存在および解剖学的見地に基づくZenker憩室との違いを認識しておく必要…
View article: Association of Plasma Claudin-5 with Age and Alzheimer Disease
Association of Plasma Claudin-5 with Age and Alzheimer Disease Open
The blood–brain barrier (BBB) plays pivotal roles in synaptic and neuronal functioning by sealing the space between adjacent microvascular endothelial cells. BBB breakdown is present in patients with mild cognitive impairment (MCI) or Alzh…
View article: Hydrolyzable and biocompatible aliphatic polycarbonates with ether-functionalized side chains attached via amide linkers
Hydrolyzable and biocompatible aliphatic polycarbonates with ether-functionalized side chains attached via amide linkers Open
Investigating polymer degradation mechanisms enables the establishment of controlled degradation techniques for the development of sustainable and recyclable materials. Hydration can play a crucial role in controlling the hydrolysis of pol…
View article: Hydrogen-Bonded Structures of Water Molecules in Hydroxy-Functionalized Nanochannels of Columnar Liquid Crystalline Nanostructured Membranes Studied by Soft X-ray Emission Spectroscopy
Hydrogen-Bonded Structures of Water Molecules in Hydroxy-Functionalized Nanochannels of Columnar Liquid Crystalline Nanostructured Membranes Studied by Soft X-ray Emission Spectroscopy Open
Here, we report a synchrotron-based high-resolution soft X-ray emission spectroscopy study on hydrogen-bonded structures of water molecules in the self-organized, hydroxy-group-functionalized one-dimensional nanochannels of liquid crystall…
View article: Evaluation of specific binding of [11C]TZ7774 to the receptor-interacting protein kinase 1 (RIPK1) in the brain
Evaluation of specific binding of [11C]TZ7774 to the receptor-interacting protein kinase 1 (RIPK1) in the brain Open
Microglia, a type of immune cells of the central nervous system, play a critical role in the pathophysiology of neurodegenerative disorders including Alzheimer's disease (AD). Recently, efforts for drug discovery have focused on modifying …
View article: Reversible Chemical Modifications of Graphene Oxide for Enhanced Viral Capture and Release in Water
Reversible Chemical Modifications of Graphene Oxide for Enhanced Viral Capture and Release in Water Open
View article: Virus adsorption and elution using cationic polymer brushes: potential applications for passive sampling in wastewater-based epidemiology
Virus adsorption and elution using cationic polymer brushes: potential applications for passive sampling in wastewater-based epidemiology Open
Efficient virus adsorption and selective elution of a nonenveloped virus are demonstrated by using cationic polymer brushes. These materials may have potential for passive sampling in wastewater-based epidemiology.
View article: Aquatic Functional Liquid Crystals: Design, Functionalization, and Molecular Simulation
Aquatic Functional Liquid Crystals: Design, Functionalization, and Molecular Simulation Open
Aquatic functional liquid crystals, which are ordered molecular assemblies that work in water environment, are described in this review. Aquatic functional liquid crystals are liquid‐crystalline (LC) materials interacting water molecules o…
View article: A novel PET probe to selectively image heat shock protein 90α/β isoforms in the brain
A novel PET probe to selectively image heat shock protein 90α/β isoforms in the brain Open
Background Heat shock proteins (HSPs), ubiquitously found proteins called molecular chaperones in the brain, play important functional roles in the neuropathological processes of Alzheimer’s disease and Lewy body disease. Of many HSP subty…
View article: Nanostructure Control in Zinc Oxide Films and Microfibers through Bioinspired Synthesis of Liquid‐Crystalline Zinc Hydroxide Carbonate; Formation of Free‐Standing Materials in Centimeter‐Level Lengths
Nanostructure Control in Zinc Oxide Films and Microfibers through Bioinspired Synthesis of Liquid‐Crystalline Zinc Hydroxide Carbonate; Formation of Free‐Standing Materials in Centimeter‐Level Lengths Open
Free‐standing zinc oxide in the forms of films and fibrous materials are expected to be used as functional devices such as piezoelectric devices and catalyst filters without being limited by the growth substrate. Herein, a synthetic morpho…
View article: Self-Assembly of Peptide-Conjugated Forklike Mesogens at Aqueous/Liquid Crystalline Interfaces: Molecular Design for Ordering Transition Induced by Specific Binding of Biomolecules
Self-Assembly of Peptide-Conjugated Forklike Mesogens at Aqueous/Liquid Crystalline Interfaces: Molecular Design for Ordering Transition Induced by Specific Binding of Biomolecules Open
Self-assembly of functional liquid crystals provides a powerful approach to the development of stimuli-responsive materials and interfaces. Here, we have designed and synthesized bioconjugated amphiphilic dendritic mesogens containing argi…
View article: A stress sensor IRE1α is required for bacterial exotoxin-induced inflammasome activation in tissue-resident macrophages
A stress sensor IRE1α is required for bacterial exotoxin-induced inflammasome activation in tissue-resident macrophages Open
Cholera toxin (CT), a bacterial exotoxin composed of one A subunit (CTA) and five B subunits (CTB), functions as an immune adjuvant. CTB can induce production of interleukin-1β (IL-1β), a proinflammatory cytokine, in synergy with a lipopol…
View article: Single-Crystal Growth of a Cubic Laves-Phase Ferromagnet HoAl2 by a Laser Floating-Zone Method
Single-Crystal Growth of a Cubic Laves-Phase Ferromagnet HoAl2 by a Laser Floating-Zone Method Open
The successful growth of single crystals of a cubic Laves-phase material HoAl2 with the space group Fd-3m is reported in this study. The crystals were grown by a floating-zone method with five laser diodes as a heat source. Al-rich feed ro…
View article: Drug interactions between ALK inhibitors and warfarin with concurrent use of bucolome: a case report
Drug interactions between ALK inhibitors and warfarin with concurrent use of bucolome: a case report Open
Background Alectinib, crizotinib, and ceritinib, are anaplastic lymphoma kinase-tyrosine kinase inhibitors (ALK-TKIs) that exhibit high protein binding, and their metabolism is associated with the cytochrome P450 (CYP) isoenzymes 2C9 or 3A…
View article: Reentrant 2D Nanostructured Liquid Crystals by Competition between Molecular Packing and Conformation: Potential Design for Multistep Switching of Ionic Conductivity
Reentrant 2D Nanostructured Liquid Crystals by Competition between Molecular Packing and Conformation: Potential Design for Multistep Switching of Ionic Conductivity Open
The front cover artwork is provided by Takashi Kato at the University of Tokyo. The image shows three assembled structures of smectic liquid crystals that show reentrant behavior. Read the full text of the Research Article at 10.1002/cphc.…