Takehiro Matsumura
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View article: Characteristics of Microaneurysm Size in Residual Edema After Intravitreal Injection of Faricimab for Diabetic Macular Edema
Characteristics of Microaneurysm Size in Residual Edema After Intravitreal Injection of Faricimab for Diabetic Macular Edema Open
Background/Objectives: Microaneurysms (MAs) are important in the pathology of diabetic macular edema (DME) and its response to anti-vascular endothelial growth factor (VEGF) therapy. This study aimed to clarify the morphological characteri…
View article: Flare levels after intravitreal injection of brolucizumab for diabetic macular edema
Flare levels after intravitreal injection of brolucizumab for diabetic macular edema Open
Purpose This study aimed to evaluate anterior flare intensity (AFI) after intravitreal injection of brolucizumab (IVBr) in patients with diabetic macular edema (DME), and to identify the factors associated with the change of AFI after IVBr…
View article: Turnover of Microaneurysms After Intravitreal Injections of Faricimab for Diabetic Macular Edema
Turnover of Microaneurysms After Intravitreal Injections of Faricimab for Diabetic Macular Edema Open
In the process of improving edema in DME with faricimab, MAs shrink and disappear, and formation of MAs are inhibited, resulting in decreased total number of MAs. Intravitreal administration of faricimab suppresses vascular permeability an…
View article: Chronic Antioxidant Capacity Loss in Anterior Chamber Environment After Iridectomy
Chronic Antioxidant Capacity Loss in Anterior Chamber Environment After Iridectomy Open
The animal model possibly predicts the vulnerability focusing on the antioxidant level in the anterior chamber environment after trabeculectomy and iridectomy per se in clinical settings.
View article: Changes in corneal higher-order aberrations during treatment for infectious keratitis
Changes in corneal higher-order aberrations during treatment for infectious keratitis Open
This study aimed to quantify the changes in corneal higher-order aberrations (HOAs) before and after treatment for infectious keratitis and verify the correlation between corneal HOAs and visual acuity. Corneal HOAs were analysed using swe…
View article: Glycemic Control after Initiation of Anti-VEGF Treatment for Diabetic Macular Edema
Glycemic Control after Initiation of Anti-VEGF Treatment for Diabetic Macular Edema Open
Diabetic macular edema (DME) induces visual disturbance, and intravitreal injections of anti-vascular endothelial growth factor (VEGF) drugs are the accepted first-line treatment. We investigate its impact on glycemic control after startin…
View article: Regional Variety of Reduction in Retinal Thickness of Diabetic Macular Edema after Anti-VEGF Treatment
Regional Variety of Reduction in Retinal Thickness of Diabetic Macular Edema after Anti-VEGF Treatment Open
Background and Objectives: The presence of refractory cases resistant to anti-vascular endothelial growth factor (VEGF) therapy for diabetic macular edema (DME) is a problem in clinical practice. This study aimed to explore the less respon…
View article: The Impact of Interval between Recurrence and Reinjection in Anti-VEGF Therapy for Diabetic Macular Edema in Pro Re Nata Regimen
The Impact of Interval between Recurrence and Reinjection in Anti-VEGF Therapy for Diabetic Macular Edema in Pro Re Nata Regimen Open
Background: Pro re nata (PRN) regimen using anti-vascular endothelial growth factor (VEGF) agent is popular for the treatment of diabetic macular edema (DME). We investigated the influence of waiting time (WT) and interval between the date…
View article: Elevated Cytokine Levels in Aqueous Humor Are Associated with Peripheral Anterior Synechiae after Penetrating Keratoplasty
Elevated Cytokine Levels in Aqueous Humor Are Associated with Peripheral Anterior Synechiae after Penetrating Keratoplasty Open
Peripheral anterior synechiae (PAS) after corneal transplantation leads to refractory glaucoma and permanent loss of vision. However, the exact mechanism remains elusive. This study aimed to evaluate the association between cytokine levels…
View article: Aqueous Cytokine Levels Are Associated With Progression of Peripheral Anterior Synechiae After Descemet Stripping Automated Endothelial Keratoplasty
Aqueous Cytokine Levels Are Associated With Progression of Peripheral Anterior Synechiae After Descemet Stripping Automated Endothelial Keratoplasty Open
Our findings indicate that chronic pathological changes in AqH can cause PAS progression and glaucoma after DSAEK.
View article: Aqueous Cytokine Levels are Associated with Progression of Peripheral Anterior Synechiae after Descemet Stripping Automated Endothelial Keratoplasty
Aqueous Cytokine Levels are Associated with Progression of Peripheral Anterior Synechiae after Descemet Stripping Automated Endothelial Keratoplasty Open
Glaucoma is a serious complication after corneal transplantation that can lead to permanent loss of vision. Peripheral anterior synechiae (PAS) leads to severe glaucoma, which is refractory to medications, however, the exact mechanism of P…
View article: Topical bromfenac reduces multiple inflammatory cytokines in the aqueous humour of pseudophakic patients
Topical bromfenac reduces multiple inflammatory cytokines in the aqueous humour of pseudophakic patients Open
Intraocular surgery is associated with increased ocular inflammation. If maintained for a prolonged period after surgery, this inflammation can cause various complications, including subconjunctival fibrosis and bleb scarring. This clinica…
View article: Comparison of the intraocular pressure following an intravitreal triamcinolone acetonide injection for diabetic macula oedema in vitrectomised and non-vitrectomised eyes
Comparison of the intraocular pressure following an intravitreal triamcinolone acetonide injection for diabetic macula oedema in vitrectomised and non-vitrectomised eyes Open
Purpose To compare the intraocular pressure (IOP) after an intravitreal triamcinolone acetonide (IVTA) between vitrectomised and non-vitrectomised eyes in patients with diabetes and diabetic macular oedema (DME). Design Retrospective compa…
View article: Microaneurysm density in residual oedema after anti‐vascular endothelial growth factor therapy for diabetic macular oedema
Microaneurysm density in residual oedema after anti‐vascular endothelial growth factor therapy for diabetic macular oedema Open
Purpose To investigate the relationship between microaneurysm (MA) density and residual oedema after intravitreal injection of an anti‐vascular endothelial growth factor agent for the treatment of diabetic macular oedema (DMO). Methods Pat…
View article: Functional and anatomical changes in diabetic macular edema after hemodialysis initiation: One-year follow-up multicenter study
Functional and anatomical changes in diabetic macular edema after hemodialysis initiation: One-year follow-up multicenter study Open
Diabetic nephropathy and retinopathy (DR) including diabetic macular edema (DME) are representative microvascular complications of diabetes. We conducted a retrospective multicenter study analyzing records from patients with DR (132 eyes i…
View article: Prospective Cohort Study on Refractive Changes after Trabeculectomy
Prospective Cohort Study on Refractive Changes after Trabeculectomy Open
We prospectively evaluated refractive changes in the eyes of 97 patients who underwent trabeculectomy at Fukui University Hospital, Fukui, Japan. The primary outcome measure was the refractive change after trabeculectomy. Secondary outcome…
View article: Randomised Clinical Trial for Postoperative Complications after Ex-PRESS Implantation versus Trabeculectomy with 2-Year Follow-Up
Randomised Clinical Trial for Postoperative Complications after Ex-PRESS Implantation versus Trabeculectomy with 2-Year Follow-Up Open
View article: Posterior subtenon infusion of triamcinolone acetonide as adjunctive treatment to panretinal photocoagulation using pattern scan laser for severe diabetic retinopathy
Posterior subtenon infusion of triamcinolone acetonide as adjunctive treatment to panretinal photocoagulation using pattern scan laser for severe diabetic retinopathy Open
View article: Randomized Clinical Trial for Postoperative Complications of Ex-PRESS Implantation versus Trabeculectomy: Complications Postoperatively of Ex-PRESS versus Trabeculectomy Study (CPETS)
Randomized Clinical Trial for Postoperative Complications of Ex-PRESS Implantation versus Trabeculectomy: Complications Postoperatively of Ex-PRESS versus Trabeculectomy Study (CPETS) Open
View article: Direct photocoagulation guided with merged retinal images for the treatment of focal diabetic macular edema.
Direct photocoagulation guided with merged retinal images for the treatment of focal diabetic macular edema. Open
View article: Effect of intravitreal triamcinolone acetonide injection at the end of vitrectomy for vitreous haemorrhage related to proliferative diabetic retinopathy
Effect of intravitreal triamcinolone acetonide injection at the end of vitrectomy for vitreous haemorrhage related to proliferative diabetic retinopathy Open
Background/Aims To investigate whether intravitreal injection of triamcinolone acetonide (IVTA) combined with vitrectomy prevents postoperative inflammation in patients with vitreous haemorrhage (VH) due to proliferative diabetic retinopat…
View article: Direct Photocoagulation Guided by Merged Retinal Images for the Treatment of Focal Diabetic Macular Edema
Direct Photocoagulation Guided by Merged Retinal Images for the Treatment of Focal Diabetic Macular Edema Open
Purpose . To introduce a novel laser photocoagulation (PC) protocol named merged image-guided PC (MIG-PC), which included merging the images of the fundus, optical coherence tomography (OCT) map, and fluorescein angiography (FA). We compar…
View article: Photocoagulation of the Retinal Nonperfusion Area Prevents the Expression of the Vascular Endothelial Growth Factor in an Animal Model
Photocoagulation of the Retinal Nonperfusion Area Prevents the Expression of the Vascular Endothelial Growth Factor in an Animal Model Open
This study is the first using an animal RVO model to demonstrate that laser photocoagulation of the retinal nonperfusion area suppresses VEGF-A expression in the retina.
View article: Panretinal Photocoagulation Using Short-Pulse Laser Induces Less Inflammation and Macular Thickening in Patients with Diabetic Retinopathy
Panretinal Photocoagulation Using Short-Pulse Laser Induces Less Inflammation and Macular Thickening in Patients with Diabetic Retinopathy Open
We compared the effect of panretinal photocoagulation (PRP) using short-pulse laser (SPL) and conventional laser, regardless of the number of spots, in terms of their effect on the progression of diabetic macular edema (DME) and anterior f…
View article: Comparison of the Inverted Internal Limiting Membrane Flap Technique and the Internal Limiting Membrane Peeling for Macular Hole with Retinal Detachment
Comparison of the Inverted Internal Limiting Membrane Flap Technique and the Internal Limiting Membrane Peeling for Macular Hole with Retinal Detachment Open
Higher rates of closed MH and retinal reattachment, and small but significant improvement in BCVA were found in the inverted ILM flap group. Based on our data, the inverted ILM flap technique may be useful in vitrectomy for MH with RD.
View article: Early Postoperative Complications of the Ex-PRESS Implantation versus Trabeculectomy: A Randomized Clinical Trial.
Early Postoperative Complications of the Ex-PRESS Implantation versus Trabeculectomy: A Randomized Clinical Trial. Open
View article: Difference in tear meniscus between conjunctivochalasis eyes and normal eyes using anterior segment optical coherence tomography.
Difference in tear meniscus between conjunctivochalasis eyes and normal eyes using anterior segment optical coherence tomography. Open
View article: Comparison of the inverted inner limiting membrane flap technique and the inner limiting membrane peeling method for macular hole with retinal detachment
Comparison of the inverted inner limiting membrane flap technique and the inner limiting membrane peeling method for macular hole with retinal detachment Open
View article: Randomized Clinical Trial for Early Postoperative Complications of Ex-PRESS Implantation versus Trabeculectomy: Complications Postoperatively of Ex-PRESS versus Trabeculectomy Study (CPETS)
Randomized Clinical Trial for Early Postoperative Complications of Ex-PRESS Implantation versus Trabeculectomy: Complications Postoperatively of Ex-PRESS versus Trabeculectomy Study (CPETS) Open
View article: Changes in Matrix Metalloproteinases in Diabetes Patients' Tears After Vitrectomy and the Relationship With Corneal Epithelial Disorder
Changes in Matrix Metalloproteinases in Diabetes Patients' Tears After Vitrectomy and the Relationship With Corneal Epithelial Disorder Open
The MMP concentration in tears of patients with diabetes was higher than in nondiabetic patients after vitrectomy. High MMP-10 levels were observed in patients with diabetes and corneal epithelial disorders after vitrectomy. Aberrant level…