2022-01-24
Dissection and Reconstitution Provide Insights into Electron Transport in the Membrane-Bound Aldehyde Dehydrogenase Complex of Gluconacetobacter diazotrophicus
2022-01-24 • Roni Miah, Shun Nina, Takeru Murate, Naoya Kataoka, Minenosuke Matsutani, Yoshitaka Ano, Kazunobu Matsushita, Toshiharu Yakushi
Two membrane-bound enzymes of acetic acid bacteria, pyrroloquinoline quinone-dependent alcohol dehydrogenase and molybdopterin-dependent aldehyde dehydrogenase (ALDH), are responsible for vinegar production. Upon the oxidation of acetaldehyde, ALDH reduces ubiquinone in the cytoplasmic membrane.