T Sugiura
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View article: Serum biomarkers during the first cycle of anti-PD-1 antibody therapies in non-small cell lung cancer
Serum biomarkers during the first cycle of anti-PD-1 antibody therapies in non-small cell lung cancer Open
Background: PD-1 blockade by anti-PD-1 antibodies restore the function of exhausted T cells and release perforin, granzyme B and cytokines which induce cytotoxic activity against tumor cells. We examined serum perforin, granzyme B and immu…