Toshihiko Sugiura
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View article: Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension: A Nationwide Prospective Multicenter Registry in Japan (J-BPA)
Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension: A Nationwide Prospective Multicenter Registry in Japan (J-BPA) Open
BACKGROUND: Over the past decade, balloon pulmonary angioplasty (BPA) for chronic thromboembolic pulmonary hypertension has shown improved outcomes with procedural refinement in expert hospitals with high procedural volume. Whether the out…
View article: A Case Report of Pulmonary Arterial Hypertension Associated With Hereditary Hemorrhagic Telangiectasia Successfully Treated With Riociguat
A Case Report of Pulmonary Arterial Hypertension Associated With Hereditary Hemorrhagic Telangiectasia Successfully Treated With Riociguat Open
Hereditary hemorrhagic telangiectasia (HHT) is a rare vascular disorder that is occasionally complicated by pulmonary hypertension (PH). In most cases where PH is associated with HHT, it is typically of a post-capillary type, while pre-cap…
View article: $NJ/\psi$ and $N\eta_c$ interactions from lattice QCD
$NJ/\psi$ and $N\eta_c$ interactions from lattice QCD Open
The interaction between nucleon and charmonia ($J/\psi$ and $\eta_c$) is expected to deepen our understanding of various aspects in nonperturbative QCD ranging from the origin of nucleon mass to $J/\psi$ mass modification in nuclear medium…
View article: Pulmonary arteriovenous malformation diagnosed by recurrent hemothorax – A case report
Pulmonary arteriovenous malformation diagnosed by recurrent hemothorax – A case report Open
A PAVM can cause recurrent hemothorax, and should be considered when evaluating a patient with hemothorax. If the cause of the hemothorax cannot be identified, a PAVM may become apparent after a long period of time.
View article: Unanticipated Hypoxemia in Late Pregnancy Revealing Hereditary Hemorrhagic Telangiectasia
Unanticipated Hypoxemia in Late Pregnancy Revealing Hereditary Hemorrhagic Telangiectasia Open
Hereditary hemorrhagic telangiectasia (HHT) complicates pregnancy due to pulmonary arteriovenous malformations (PAVMs), which risk rupture from hemodynamic changes. A 26-year-old woman at 32 weeks' gestation with refractory cough, dyspnea,…
View article: Significance of Normal Lung Volume on Quantitative CT Imaging Analysis in Group 1 and Group 3 Pulmonary Hypertension
Significance of Normal Lung Volume on Quantitative CT Imaging Analysis in Group 1 and Group 3 Pulmonary Hypertension Open
Background: Patients with concurrent pulmonary hypertension (PH) and parenchymal lung diseases have a high risk of mortality. However, whether their outcomes are related to low normal lung volume (NLV) resulting from parenchymal lung disea…
View article: Artificial intelligence-based model for predicting pulmonary arterial hypertension on chest x-ray images
Artificial intelligence-based model for predicting pulmonary arterial hypertension on chest x-ray images Open
View article: A 65-Year-Old Man with Refractory Hemoptysis Associated with Chronic Progressive Pulmonary Aspergillosis Who Failed to Respond to Combined Endobronchial Occlusion and Bronchial Artery Embolization: A Case Report and Literature Review
A 65-Year-Old Man with Refractory Hemoptysis Associated with Chronic Progressive Pulmonary Aspergillosis Who Failed to Respond to Combined Endobronchial Occlusion and Bronchial Artery Embolization: A Case Report and Literature Review Open
BACKGROUND Hemoptysis due to airway hemorrhage is treated with hemostatic agents, bronchial artery embolization (BAE), or surgical resection. We present the case of a 65-year-old man with refractory hemoptysis associated with chronic progr…
View article: Macitentan Administration for Pulmonary Hypertension Due to β-thalassemia with Multiple Organ Failure
Macitentan Administration for Pulmonary Hypertension Due to β-thalassemia with Multiple Organ Failure Open
A 51-year-old Thai woman diagnosed with β-thalassemia underwent regular blood transfusion and iron-chelating therapy. However, after voluntarily discontinuing treatment, the patient developed progressive dyspnea and was diagnosed with pulm…
View article: Is Ethereum Proof of Stake Sustainable? $-$ Considering from the Perspective of Competition Among Smart Contract Platforms $-$
Is Ethereum Proof of Stake Sustainable? $-$ Considering from the Perspective of Competition Among Smart Contract Platforms $-$ Open
Since the Merge update upon which Ethereum transitioned to Proof of Stake, it has been touted that it resulted in lower power consumption and increased security. However, even if that is the case, can this state be sustained? In this paper…
View article: Artificial intelligence-based model for predicting pulmonary arterial hypertension on chest radiograph
Artificial intelligence-based model for predicting pulmonary arterial hypertension on chest radiograph Open
Background Pulmonary arterial hypertension is a severe condition. Despite advances in targeted treatments for it, diagnostic delays have yet to improve. Early referral to a specialized hospital is important because a longer diagnostic inte…
View article: Role of Fibrin Monomer Complex in Coronavirus Disease 2019 for Venous Thromboembolism and the Prognosis
Role of Fibrin Monomer Complex in Coronavirus Disease 2019 for Venous Thromboembolism and the Prognosis Open
Objective Venous thromboembolism (VTE) is a common complication of severe coronavirus disease 2019 (COVID-19) and is associated with its prognosis. The fibrin monomer complex (FMC), a marker of thrombin generation, is reportedly useful in …
View article: Clinical significance of lung cross‐sectional area measured by computed tomography in chronic thromboembolic pulmonary hypertension: The correlation with pulmonary hemodynamics and the limitations
Clinical significance of lung cross‐sectional area measured by computed tomography in chronic thromboembolic pulmonary hypertension: The correlation with pulmonary hemodynamics and the limitations Open
The percentage cross‐sectional area of the lung under five (%CSA <5 ) is the percentage of pulmonary vessels with <5 mm 2 area relative to the total lung area on computed tomography (CT). The extent that %CSA <5 is related to pulmonary hem…
View article: Impact of residual pulmonary hypertension on long‐term outcomes after pulmonary endarterectomy in the modern era
Impact of residual pulmonary hypertension on long‐term outcomes after pulmonary endarterectomy in the modern era Open
Residual pulmonary hypertension (PH) negatively impacts long‐term results following pulmonary endarterectomy (PEA) for chronic thromboembolic pulmonary hypertension (CTEPH). We sought to reveal whether modern PH therapy with PH‐targeted me…
View article: Is Ethereum Proof of Stake Sustainable? — Considering from the Perspective of Competition Among Smart Contract Platforms
Is Ethereum Proof of Stake Sustainable? — Considering from the Perspective of Competition Among Smart Contract Platforms Open
View article: Pharmacological and Clinical data of oral alpha 4 integrin antagonist, Carotegrast methyl, CAROGRA<sup>®</sup>
Pharmacological and Clinical data of oral alpha 4 integrin antagonist, Carotegrast methyl, CAROGRA<sup>®</sup> Open
Carotegrast-methyl (brand name: CAROGRA® Tablets) is a new chemical entity created by Ajinomoto Pharmaceuticals Co., Ltd. (currently EA Pharma Co., Ltd.) as an α4 integrin inhibitor. In vivo, it exerts an anti-inflammatory effec…
View article: Two cases of pulmonary arterial hypertension with specific vascular Мalformations and unique eosinophilic inflammation in carriers of the RNF213 p. Arg4810Lys variant: Case series
Two cases of pulmonary arterial hypertension with specific vascular Мalformations and unique eosinophilic inflammation in carriers of the RNF213 p. Arg4810Lys variant: Case series Open
RNF213 p.Arg4810Lys is linked to various vascular diseases, including pulmonary arterial hypertension (PAH); however, its pathogenesis remains unclear. Here, we report the unique features of two cases of severe PAH with this variant…
View article: Venous Stent Placement for Malignant Vena Cava Syndrome in a Patient with Liposarcoma
Venous Stent Placement for Malignant Vena Cava Syndrome in a Patient with Liposarcoma Open
BACKGROUND Reports of venous stenting for inferior vena cava (IVC) syndrome (IVCS) due to sarcoma are limited, and the treatment's efficacy and safety are not clear. CASE REPORT A 36-year-old woman with myxoid liposarcoma was admitted to t…
View article: Chronic Expanding Haematoma Causing Stenosis of the Right Ventricular Outflow Tract and Pulmonary Hypertension
Chronic Expanding Haematoma Causing Stenosis of the Right Ventricular Outflow Tract and Pulmonary Hypertension Open
A chronic expanding haematoma (CEH) is an encapsulated mass that gradually increases in size from repeated internal bleeding and neovascularization. We herein report a 69-year-old man who was admitted with dyspnoea on exertion after underg…
View article: Characterization of LCR Parallel-Type Electromagnetic Shunt Damper for Superconducting Magnetic Levitation
Characterization of LCR Parallel-Type Electromagnetic Shunt Damper for Superconducting Magnetic Levitation Open
This study investigated the effect of electromagnetic shunt dampers on the resonance amplitude reduction in a superconducting magnetic levitation system. There are two types of electromagnetic shunt dampers, series type and parallel type, …
View article: Pulmonary Veno-occlusive Disease that Developed Following Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia
Pulmonary Veno-occlusive Disease that Developed Following Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia Open
We herein report a case of pulmonary veno-occlusive disease (PVOD) induced by allo-hematopoietic stem cell transplantation (HSCT) in a 48-year-old man who was diagnosed with acute myeloid leukemia. Five months after transplantation, he dev…
View article: Development of venous thromboembolism in an elderly man with plaque psoriasis and antiphospholipid syndrome: A case report
Development of venous thromboembolism in an elderly man with plaque psoriasis and antiphospholipid syndrome: A case report Open
Antiphospholipid syndrome (APS) is a systemic autoimmune disease associated with arterial and venous thromboembolism (VTE) or recurrent fetal loss in individuals carrying antiphospholipid antibodies (aPL). We report a case of a 76-year-old…
View article: Altered gut microbiota and its association with inflammation in patients with chronic thromboembolic pulmonary hypertension: a single-center observational study in Japan
Altered gut microbiota and its association with inflammation in patients with chronic thromboembolic pulmonary hypertension: a single-center observational study in Japan Open
View article: Tolerability of prone positioning in non‐intubated patients with hypoxaemia due to <scp>COVID</scp>‐19‐related pneumonia
Tolerability of prone positioning in non‐intubated patients with hypoxaemia due to <span>COVID</span>‐19‐related pneumonia Open
Coronavirus disease 2019 (COVID-19) may result in acute respiratory distress syndrome.1 Prone positioning (PP) has been reported to improve the clinical condition of patients with COVID-19,2-4 and has often been performed on non-intubated …
View article: A Case of Primary Racemose Hemangioma with Endobronchial Lesions Demonstrating Recurrent Hemoptysis Initially Treated with Bronchial Arterial Embolization
A Case of Primary Racemose Hemangioma with Endobronchial Lesions Demonstrating Recurrent Hemoptysis Initially Treated with Bronchial Arterial Embolization Open
View article: A case of primary racemose hemangioma with endobronchial lesions demonstrating recurrent hemoptysis initially treated with bronchial arterial embolization
A case of primary racemose hemangioma with endobronchial lesions demonstrating recurrent hemoptysis initially treated with bronchial arterial embolization Open
View article: Vascular involvement in chronic thromboembolic pulmonary hypertension is associated with spirometry obstructive impairment
Vascular involvement in chronic thromboembolic pulmonary hypertension is associated with spirometry obstructive impairment Open
Background Chronic thromboembolic pulmonary hypertension (CTEPH) is a type of pulmonary hypertension caused by persistent thromboembolism of the pulmonary arteries. In clinical practice, CTEPH patients often show obstructive ventilatory im…
View article: Interventricular septal curvature as an additional echocardiographic parameter for evaluating chronic thromboembolic pulmonary hypertension: a single-center retrospective study
Interventricular septal curvature as an additional echocardiographic parameter for evaluating chronic thromboembolic pulmonary hypertension: a single-center retrospective study Open
View article: A case of pulmonary arterial hypertension with V/Q <scp>SPECT</scp>/<scp>CT</scp> that showed localized uptake of <scp>99mTc</scp> just below the pleura and a unique distribution
A case of pulmonary arterial hypertension with V/Q <span>SPECT</span>/<span>CT</span> that showed localized uptake of <span>99mTc</span> just below the pleura and a unique distribution Open
Pulmonary hypertension (PH) is a life‐threatening disorder, which originates from various aetiologies. Ventilation–perfusion (V/Q) scanning is commonly used to evaluate the differential diagnosis of PH. Meanwhile, previous studies have sho…
View article: Successful treatment of bilateral multiple pulmonary arteriovenous malformations in a patient with brain abscess and severe hypoxemia using a combination of transcatheter embolotherapy and surgical resection: a case report
Successful treatment of bilateral multiple pulmonary arteriovenous malformations in a patient with brain abscess and severe hypoxemia using a combination of transcatheter embolotherapy and surgical resection: a case report Open