Explanipedia

Stool shed cell transcriptomics mirrors tumor biology and enables colorectal cancer diagnosis Open

Keren Bahar Halpern, Ilan Kent, Oran Yakubovsky, Shani Ben‐Moshe, Tal Barkai , et al. · 2025

Screening and molecular characterization of human intestinal pathologies such as colorectal cancer (CRC) currently depends on colonoscopy, an invasive procedure associated with risks and poor adherence. A non-invasive method that captures …

Transcriptomic profiling of shed cells enables spatial mapping of cellular turnover in human organs Open

Tal Barkai, Oran Yakubovsky, Yael Korem Kohanim, Keren Bahar Halpern, Sapir Shir , et al. · 2025

Single-cell atlases provide valuable insights into gene expression states but lack information on cellular dynamics. Understanding cell turnover rates—the time between a cell’s birth and death—can shed light on stemness potential and susce…

Unilateral Increase of Gustatory Thresholds in Acute Otitis Media: A Pilot Study Open

Linor Klein, Tal Barkai, Narin N. Carmel Neiderman, Mickey Scheinowitz, Amir Dagan , et al. · 2023

BACKGROUND: To evaluate chorda tympani nerve function as measured by unilateral increases of gustatory thresholds in the presence of ipsilateral acute otitis media. METHODS: Prospective clinical study comparing electrogustometric measureme…

Late diagnosis of chronic granulomatous disease Open

Tal Barkai, Raz Somech, Arnon Broides, Ronit Gavrieli, Baruch Wolach , et al. · 2020

Summary Modern era advancements in medical care, with improved treatment of infections, can result in delayed diagnosis of congenital immunodeficiencies. In this study we present a retrospective cohort of 16 patients diagnosed with Chronic…

Voltage-Gated Sodium Channels in Neocortical Pyramidal Neurons Display Cole-Moore Activation Kinetics Open

Mara Almog, Tal Barkai, Angelika Lampert, Alon Korngreen · 2018

Exploring the properties of action potentials is a crucial step toward a better understanding of the computational properties of single neurons and neural networks. The voltage-gated sodium channel is a key player in action potential gener…

Voltage-gated sodium channels in neocortical pyramidal neurons display Cole-Moore activation kinetics Open

Mara Almog, Tal Barkai, Angelika Lampert, Alon Korngreen · 2017

Exploring the properties of action potentials is a crucial step towards a better understanding of the computational properties of single neurons and neural networks. The voltage-gated sodium channel is a key player in action potential gene…

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